Myricetin: A comprehensive review on its biological potentials.
Muhammad ImranFarhan SaeedGhulam HussainAli ImranZaffar MehmoodTanweer Aslam GondalAhmed El-GhorabIshtiaque AhmadRaffaele PezzaniMuhammad Umair ArshadUmar BachaMohammad Ali ShariartiAbdur RaufNaveed MuhammadZafar Ali ShahGokhan ZenginSaiful IslamPublished in: Food science & nutrition (2021)
Myricetin is a critical nutritive component of diet providing immunological protection and beneficial for maintaining good health. It is found in fruits, vegetables, tea, and wine. The families Myricaceae, Polygonaceae, Primulaceae, Pinaceae, and Anacardiaceae are the richest sources of myricetin. Different researchers explored the therapeutic potential of this valuable constituent such as anticancer, antidiabetic, antiobesity, cardiovascular protection, osteoporosis protection, anti-inflammatory, and hepatoprotective. In addition to these, the compound has been tested for cancer and diabetic mellitus during clinical trials. Health benefits of myricetin are related to its impact on different cell processes, such as apoptosis, glycolysis, cell cycle, energy balance, lipid level, serum protein concentrations, and osteoclastogenesis. This review explored the potential health benefits of myricetin with a specific emphasis on its mechanism of action, considering the most updated and novel findings in the field.
Keyphrases
- cell cycle
- public health
- healthcare
- clinical trial
- mental health
- human health
- health information
- anti inflammatory
- cell proliferation
- health promotion
- single cell
- cell death
- squamous cell carcinoma
- endoplasmic reticulum stress
- randomized controlled trial
- cell therapy
- fatty acid
- drinking water
- climate change
- bone mineral density
- mesenchymal stem cells
- heavy metals
- social media
- squamous cell
- inflammatory response
- amino acid
- phase ii
- phase iii
- protein protein