Multicentre derivation and validation of a colitis-associated colorectal cancer risk prediction web tool.

Kit Curtius Misha KabirIbrahim Al BakirChang Ho Ryan ChoiJuanda L HartonoMichael JohnsonJames E Eastnull nullJames O LindsayRoser VegaSiwan Thomas-GibsonJanindra WarusavitarneAna WilsonTrevor A GrahamAilsa Hart

Published in: Gut (2021)

Multicohort validation confirms that patients with large, unresected, multifocal LGD and recent moderate/severe inflammation are at highest risk of developing AN. Personalised risk prediction provided via the Ulcerative Colitis-Cancer Risk Estimator (www.UC-CaRE.uk) can support treatment decision-making.

Keyphrases

ulcerative colitis
decision making
healthcare
oxidative stress
clinical trial
palliative care
cross sectional
quality improvement
study protocol
randomized controlled trial
early onset
drug induced
double blind
replacement therapy