Trevor A Graham (Trevor Graham)

ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 83

Top Venues

Nature genetics

Nature communications

Research square

The Journal of pathology

Queen Mary University of London

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Queen Mary University of London Jan 09 2013

United Kingdom

Professor :: Barts Cancer Institute

Publications

Hamzeh Kayhanian, William Cross, Suzanne E M van der Horst, Panagiotis Barmpoutis, Eszter Lakatos, Giulio Caravagna, Luis Zapata, Arne Van Hoeck, Sjors Middelkamp, Kevin Litchfield, Christopher Steele, William Waddingham, Dominic Patel, Salvatore Milite, Chen Jin, Ann-Marie C Baker, Daniel C Alexander, Khurum Khan, Daniel Hochhauser, Marco Novelli, Benjamin Werner, Ruben van Boxtel, Joris H Hageman, Julian R Buissant des Amorie, Josep Linares, Marjolijn J L Ligtenberg, Iris D Nagtegaal, Miangela M Laclé, Leon M G Moons, Lodewijk A A Brosens, Nischalan Pillay, Andrea Sottoriva, Trevor A Graham, Manuel Rodriguez, Kai-Keen Shiu, Hugo J G Snippert, Marnix Jansen
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer. Nature genetics 56 (7) (2024)
Ibrahim Al Bakir, Kit Curtius, George D Cresswell, Heather E Grant, Nadia Nasreddin, Kane Smith, Salpie Nowinski, Qingli Guo, Hayley L Belnoue-Davis, Jennifer Fisher, Theo Clarke, Christopher Kimberley, Maximilian Mossner, Philip D Dunne, Maurice B Loughrey, Ally Speight, James E East, Nicholas A Wright, Manuel Rodriguez-Justo, Marnix Jansen, Morgan Moorghen, Ann-Marie Baker, Simon J Leedham, Ailsa L Hart, Trevor A Graham
Low coverage whole genome sequencing of low-grade dysplasia strongly predicts colorectal cancer risk in ulcerative colitis. medRxiv : the preprint server for health sciences (2024)
Alex J Cornish, Andreas J Gruber, Ben Kinnersley, Daniel Chubb, Anna Frangou, Giulio Caravagna, Boris Noyvert, Eszter Lakatos, Henry M Wood, Steve Thorn, Richard Culliford, Claudia Arnedo-Pac, Jacob Househam, William Cross, Amit Sud, Philip J Law, Maire Ni Leathlobhair, Aliah Hawari, Connor Woolley, Kitty Sherwood, Nathalie Feeley, Güler Gül, Juan Fernandez-Tajes, Luis Zapata, Ludmil B Alexandrov, Nirupa Murugaesu, Alona Sosinsky, Jonathan Mitchell, Núria López-Bigas, Philip Quirke, David N Church, Ian P M Tomlinson, Andrea Sottoriva, Trevor A Graham, David C Wedge, Richard S Houlston
The genomic landscape of 2,023 colorectal cancers. Nature (2024)
Alex J Cornish, Andreas J Gruber, Ben Kinnersley, Daniel Chubb, Anna Frangou, Giulio Caravagna, Boris Noyvert, Eszter Lakatos, Henry M Wood, Steve Thorn, Richard Culliford, Claudia Arnedo-Pac, Jacob Househam, William Cross, Amit Sud, Philip J Law, Maire Ni Leathlobhair, Aliah Hawari, Connor Woolley, Kitty Sherwood, Nathalie Feeley, Güler Gül, Juan Fernandez-Tajes, Luis Zapata, Ludmil B Alexandrov, Nirupa Murugaesu, Alona Sosinsky, Jonathan Mitchell, Núria López-Bigas, Philip Quirke, David N Church, Ian P M Tomlinson, Andrea Sottoriva, Trevor A Graham, David C Wedge, Richard S Houlston
The genomic landscape of 2,023 colorectal cancers. Nature (2024)
Eszter Lakatos, Vinaya Gunasri, Luis Zapata, Jacob Househam, Timon Heide, Nicholas Trahearn, Ottilie Swinyard, Luis H Cisneros, Claire Lynn, Maximilian Mossner, Christopher Kimberley, Inmaculada Spiteri, George D Cresswell, Gerard Llibre-Palomar, Miriam Mitchison, Carlo C Maley, Marnix Jansen, Manuel Rodriguez, John A Bridgewater, Ann-Marie C Baker, Andrea Sottoriva, Trevor A Graham
Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer. bioRxiv : the preprint server for biology (2024)
Ann-Marie C Baker, Gayathri Nageswaran, Pablo Nenclares, Tahel Ronel, Kane Smith, Christopher Kimberley, Miangela M Laclé, Shreerang A Bhide, Kevin J Harrington, Alan A Melcher, Manuel Rodriguez, Benjamin M Chain, Trevor A Graham
FUME-TCRseq Enables Sensitive and Accurate Sequencing of the T-cell Receptor from Limited Input of Degraded RNA. Cancer research 84 (10) (2024)
Eszter Lakatos, Vinaya Gunasri, Luis Zapata, Jacob Househam, Timon Heide, Nicholas Trahearn, Ottilie Swinyard, Luis H Cisneros, Claire Lynn, Maximilian Mossner, Christopher Kimberley, Inmaculada Spiteri, George D Cresswell, Gerard Llibre-Palomar, Miriam Mitchison, Carlo C Maley, Marnix Jansen, Manuel Rodriguez, John A Bridgewater, Ann-Marie C Baker, Andrea Sottoriva, Trevor A Graham
Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer. bioRxiv : the preprint server for biology (2024)
Hamzeh Kayhanian, William Cross, Suzanne E M van der Horst, Panagiotis Barmpoutis, Eszter Lakatos, Giulio Caravagna, Luis Zapata, Arne Van Hoeck, Sjors Middelkamp, Kevin Litchfield, Christopher Steele, William Waddingham, Dominic Patel, Salvatore Milite, Chen Jin, Ann-Marie C Baker, Daniel C Alexander, Khurum Khan, Daniel Hochhauser, Marco Novelli, Benjamin Werner, Ruben van Boxtel, Joris H Hageman, Julian R Buissant des Amorie, Josep Linares, Marjolijn J L Ligtenberg, Iris D Nagtegaal, Miangela M Laclé, Leon M G Moons, Lodewijk A A Brosens, Nischalan Pillay, Andrea Sottoriva, Trevor A Graham, Manuel Rodriguez, Kai-Keen Shiu, Hugo J G Snippert, Marnix Jansen
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer. Nature genetics (2024)
Eszter Lakatos, Vinaya Gunasri, Luis Zapata, Jacob Househam, Timon Heide, Nicholas Trahearn, Ottilie Swinyard, Luis H Cisneros, Claire Lynn, Maximilian Mossner, Christopher Kimberley, Inmaculada Spiteri, George D Cresswell, Gerard Llibre-Palomar, Miriam Mitchison, Carlo C Maley, Marnix Jansen, Manuel Rodriguez, John A Bridgewater, Ann-Marie C Baker, Andrea Sottoriva, Trevor A Graham
Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer. bioRxiv : the preprint server for biology (2024)
Hamzeh Kayhanian, William Cross, Suzanne E M van der Horst, Panagiotis Barmpoutis, Eszter Lakatos, Giulio Caravagna, Luis Zapata, Arne Van Hoeck, Sjors Middelkamp, Kevin Litchfield, Christopher Steele, William Waddingham, Dominic Patel, Salvatore Milite, Chen Jin, Ann-Marie C Baker, Daniel C Alexander, Khurum Khan, Daniel Hochhauser, Marco Novelli, Benjamin Werner, Ruben van Boxtel, Joris H Hageman, Julian R Buissant des Amorie, Josep Linares, Marjolijn J L Ligtenberg, Iris D Nagtegaal, Miangela M Laclé, Leon M G Moons, Lodewijk A A Brosens, Nischalan Pillay, Andrea Sottoriva, Trevor A Graham, Manuel Rodriguez, Kai-Keen Shiu, Hugo J G Snippert, Marnix Jansen
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer. Nature genetics 56 (7) (2024)
Hamzeh Kayhanian, William Cross, Suzanne E M van der Horst, Panagiotis Barmpoutis, Eszter Lakatos, Giulio Caravagna, Luis Zapata, Arne Van Hoeck, Sjors Middelkamp, Kevin Litchfield, Christopher Steele, William Waddingham, Dominic Patel, Salvatore Milite, Chen Jin, Ann-Marie C Baker, Daniel C Alexander, Khurum Khan, Daniel Hochhauser, Marco Novelli, Benjamin Werner, Ruben van Boxtel, Joris H Hageman, Julian R Buissant des Amorie, Josep Linares, Marjolijn J L Ligtenberg, Iris D Nagtegaal, Miangela M Laclé, Leon M G Moons, Lodewijk A A Brosens, Nischalan Pillay, Andrea Sottoriva, Trevor A Graham, Manuel Rodriguez, Kai-Keen Shiu, Hugo J G Snippert, Marnix Jansen
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer. Nature genetics 56 (7) (2024)
Ibrahim Al Bakir, Kit Curtius, George D Cresswell, Heather E Grant, Nadia Nasreddin, Kane Smith, Salpie Nowinski, Qingli Guo, Hayley L Belnoue-Davis, Jennifer Fisher, Theo Clarke, Christopher Kimberley, Maximilian Mossner, Philip D Dunne, Maurice B Loughrey, Ally Speight, James E East, Nicholas A Wright, Manuel Rodriguez-Justo, Marnix Jansen, Morgan Moorghen, Ann-Marie Baker, Simon J Leedham, Ailsa L Hart, Trevor A Graham
Low coverage whole genome sequencing of low-grade dysplasia strongly predicts colorectal cancer risk in ulcerative colitis. medRxiv : the preprint server for health sciences (2024)
Ann-Marie C Baker, Gayathri Nageswaran, Pablo Nenclares, Tahel Ronel, Kane Smith, Christopher Kimberley, Miangela M Laclé, Shreerang A Bhide, Kevin J Harrington, Alan A Melcher, Manuel Rodriguez, Benjamin M Chain, Trevor A Graham
FUME-TCRseq Enables Sensitive and Accurate Sequencing of the T-cell Receptor from Limited Input of Degraded RNA. Cancer research 84 (10) (2024)
Ibrahim Al Bakir, Kit Curtius, George D Cresswell, Heather E Grant, Nadia Nasreddin, Kane Smith, Salpie Nowinski, Qingli Guo, Hayley L Belnoue-Davis, Jennifer Fisher, Theo Clarke, Christopher Kimberley, Maximilian Mossner, Philip D Dunne, Maurice B Loughrey, Ally Speight, James E East, Nicholas A Wright, Manuel Rodriguez-Justo, Marnix Jansen, Morgan Moorghen, Ann-Marie Baker, Simon J Leedham, Ailsa L Hart, Trevor A Graham
Low coverage whole genome sequencing of low-grade dysplasia strongly predicts colorectal cancer risk in ulcerative colitis. medRxiv : the preprint server for health sciences (2024)
Hamzeh Kayhanian, William Cross, Suzanne E M van der Horst, Panagiotis Barmpoutis, Eszter Lakatos, Giulio Caravagna, Luis Zapata, Arne Van Hoeck, Sjors Middelkamp, Kevin Litchfield, Christopher Steele, William Waddingham, Dominic Patel, Salvatore Milite, Chen Jin, Ann-Marie C Baker, Daniel C Alexander, Khurum Khan, Daniel Hochhauser, Marco Novelli, Benjamin Werner, Ruben van Boxtel, Joris H Hageman, Julian R Buissant des Amorie, Josep Linares, Marjolijn J L Ligtenberg, Iris D Nagtegaal, Miangela M Laclé, Leon M G Moons, Lodewijk A A Brosens, Nischalan Pillay, Andrea Sottoriva, Trevor A Graham, Manuel Rodriguez, Kai-Keen Shiu, Hugo J G Snippert, Marnix Jansen
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer. Nature genetics 56 (7) (2024)
Ann-Marie C Baker, Gayathri Nageswaran, Pablo Nenclares, Tahel Ronel, Kane Smith, Christopher Kimberley, Miangela M Laclé, Shreerang A Bhide, Kevin J Harrington, Alan A Melcher, Manuel Rodriguez, Benjamin M Chain, Trevor A Graham
FUME-TCRseq enables sensitive and accurate sequencing of the T-cell receptor from limited input of degraded RNA. Cancer research (2024)
Ann-Marie C Baker, Gayathri Nageswaran, Pablo Nenclares, Tahel Ronel, Kane Smith, Christopher Kimberley, Miangela M Laclé, Shreerang A Bhide, Kevin J Harrington, Alan A Melcher, Manuel Rodriguez, Benjamin M Chain, Trevor A Graham
FUME-TCRseq Enables Sensitive and Accurate Sequencing of the T-cell Receptor from Limited Input of Degraded RNA. Cancer research 84 (10) (2024)
Luis Zapata, Giulio Caravagna, Marc J Williams, Eszter Lakatos, Khalid AbdulJabbar, Benjamin Werner, Diego Chowell, Chela James, Lucie Gourmet, Salvatore Milite, Ahmet Acar, Nadeem Riaz, Timothy A Chan, Trevor A Graham, Andrea Sottoriva
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors. Nature genetics (2023)
Bingjie Chen, Daniele Ramazzotti, Timon Heide, Inmaculada Spiteri, Javier Fernández-Mateos, Chela James, Luca Magnani, Trevor A Graham, Andrea Sottoriva
Contribution of pks + E. coli mutations to colorectal carcinogenesis. Nature communications 14 (1) (2023)
Luis Zapata, Giulio Caravagna, Marc J Williams, Eszter Lakatos, Khalid AbdulJabbar, Benjamin Werner, Diego Chowell, Chela James, Lucie Gourmet, Salvatore Milite, Ahmet Acar, Nadeem Riaz, Timothy A Chan, Trevor A Graham, Andrea Sottoriva
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors. Nature genetics 55 (3) (2023)
Luis Zapata, Giulio Caravagna, Marc J Williams, Eszter Lakatos, Khalid AbdulJabbar, Benjamin Werner, Diego Chowell, Chela James, Lucie Gourmet, Salvatore Milite, Ahmet Acar, Nadeem Riaz, Timothy A Chan, Trevor A Graham, Andrea Sottoriva
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors. Nature genetics 55 (3) (2023)
Zachary Compton, Valerie Harris, Walker Mellon, Shawn Rupp, Diego Mallo, Stefania Kapsetaki, Mallory Wilmot, Ryan Kennington, Kathleen Noble, Cristina Baciu, Lucia Ramirez, Ashley Peraza, Brian Martins, Sushil Sudhakar, Selin Aksoy, Gabriela Furukawa, Orsolya Vincze, Mathieu Giraudeau, Elizabeth Duke, Simon Spiro, Edmund J Flach, Hannah Davidson, Ashley Zehnder, Trevor A Graham, Brigid Troan, Tara M Harrison, Marc Tollis, Joshua D Schiffman, Athena Aktipis, Lisa M Abegglen, Carlo C Maley, Amy Boddy
Cancer Prevalence Across Vertebrates. Research square (2023)
Magnus J Haughey, Aleix Bassolas, Sandro Sousa, Ann-Marie C Baker, Trevor A Graham, Vincenzo Nicosia, Weini Huang
First passage time analysis of spatial mutation patterns reveals sub-clonal evolutionary dynamics in colorectal cancer. PLoS computational biology 19 (3) (2023)
Khalid AbdulJabbar, Simon P Castillo, Katherine Hughes, Hannah Davidson, Amy Μ Boddy, Lisa M Abegglen, Lucia Minoli, Selina Iussich, Elizabeth P Murchison, Trevor A Graham, Simon Spiro, Carlo C Maley, Luca Aresu, Chiara Palmieri, Yinyin Yuan
Bridging clinic and wildlife care with AI-powered pan-species computational pathology. Nature communications 14 (1) (2023)
Khalid AbdulJabbar, Simon P Castillo, Katherine Hughes, Hannah Davidson, Amy Μ Boddy, Lisa M Abegglen, Lucia Minoli, Selina Iussich, Elizabeth P Murchison, Trevor A Graham, Simon Spiro, Carlo C Maley, Luca Aresu, Chiara Palmieri, Yinyin Yuan
Bridging clinic and wildlife care with AI-powered pan-species computational pathology. Nature communications 14 (1) (2023)
Melissa Barroux, Jacob Househam, Eszter Lakatos, Tahel Ronel, Ann-Marie C Baker, Henrike Sali, Max Mossner, Kane Smith, Chris Kimberley, Salpie Nowinski, Alison Berner, Vinaya Gunasri, Marnix Jansen, Giulio Caravagna, Katja Steiger, Julia Slotta-Huspenina, Wilko Weichert, Markus Alberstmeier, Benjamin M Chain, Helmut Friess, Bertram Bengsch, Roland Schmid, Jens Thomas Siveke, Michael Quante, Trevor A Graham
Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of oesophagael adenocarcinoma. Research square (2023)
Magnus J Haughey, Aleix Bassolas, Sandro Sousa, Ann-Marie C Baker, Trevor A Graham, Vincenzo Nicosia, Weini Huang
First passage time analysis of spatial mutation patterns reveals sub-clonal evolutionary dynamics in colorectal cancer. PLoS computational biology 19 (3) (2023)
Chandler D Gatenbee, Ann-Marie C Baker, Sandhya Prabhakaran, Ottilie Swinyard, Robbert J C Slebos, Gunjan Mandal, Eoghan Mulholland, Noemi Andor, Andriy Marusyk, Simon Leedham, José R Conejo-Garcia, Christine H Chung, Mark Robertson-Tessi, Trevor A Graham, Alexander A R A Anderson
Virtual alignment of pathology image series for multi-gigapixel whole slide images. Nature communications 14 (1) (2023)
Luis Zapata, Giulio Caravagna, Marc J Williams, Eszter Lakatos, Khalid AbdulJabbar, Benjamin Werner, Diego Chowell, Chela James, Lucie Gourmet, Salvatore Milite, Ahmet Acar, Nadeem Riaz, Timothy A Chan, Trevor A Graham, Andrea Sottoriva
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors. Nature genetics 55 (3) (2023)
Melissa Barroux, Jacob Househam, Eszter Lakatos, Tahel Ronel, Ann-Marie C Baker, Henrike Sali, Max Mossner, Kane Smith, Chris Kimberley, Salpie Nowinski, Alison Berner, Vinaya Gunasri, Marnix Jansen, Giulio Caravagna, Katja Steiger, Julia Slotta-Huspenina, Wilko Weichert, Markus Alberstmeier, Benjamin M Chain, Helmut Friess, Bertram Bengsch, Roland Schmid, Jens Thomas Siveke, Michael Quante, Trevor A Graham
Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of oesophagael adenocarcinoma. Research square (2023)
Melissa Barroux, Jacob Househam, Eszter Lakatos, Tahel Ronel, Ann-Marie C Baker, Henrike Sali, Max Mossner, Kane Smith, Chris Kimberley, Salpie Nowinski, Alison Berner, Vinaya Gunasri, Marnix Jansen, Giulio Caravagna, Katja Steiger, Julia Slotta-Huspenina, Wilko Weichert, Markus Alberstmeier, Benjamin M Chain, Helmut Friess, Bertram Bengsch, Roland Schmid, Jens Thomas Siveke, Michael Quante, Trevor A Graham
Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of oesophagael adenocarcinoma. Research square (2023)
Melissa Barroux, Jacob Househam, Eszter Lakatos, Tahel Ronel, Ann-Marie C Baker, Henrike Sali, Max Mossner, Kane Smith, Chris Kimberley, Salpie Nowinski, Alison Berner, Vinaya Gunasri, Marnix Jansen, Giulio Caravagna, Katja Steiger, Julia Slotta-Huspenina, Wilko Weichert, Markus Alberstmeier, Benjamin M Chain, Helmut Friess, Bertram Bengsch, Roland Schmid, Jens Thomas Siveke, Michael Quante, Trevor A Graham
Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of oesophagael adenocarcinoma. Research square (2023)
Khalid AbdulJabbar, Simon P Castillo, Katherine Hughes, Hannah Davidson, Amy Μ Boddy, Lisa M Abegglen, Lucia Minoli, Selina Iussich, Elizabeth P Murchison, Trevor A Graham, Simon Spiro, Carlo C Maley, Luca Aresu, Chiara Palmieri, Yinyin Yuan
Bridging clinic and wildlife care with AI-powered pan-species computational pathology. Nature communications 14 (1) (2023)
Luis Zapata, Giulio Caravagna, Marc J Williams, Eszter Lakatos, Khalid AbdulJabbar, Benjamin Werner, Diego Chowell, Chela James, Lucie Gourmet, Salvatore Milite, Ahmet Acar, Nadeem Riaz, Timothy A Chan, Trevor A Graham, Andrea Sottoriva
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors. Nature genetics 55 (3) (2023)
Khalid AbdulJabbar, Simon P Castillo, Katherine Hughes, Hannah Davidson, Amy Μ Boddy, Lisa M Abegglen, Lucia Minoli, Selina Iussich, Elizabeth P Murchison, Trevor A Graham, Simon Spiro, Carlo C Maley, Luca Aresu, Chiara Palmieri, Yinyin Yuan
Bridging clinic and wildlife care with AI-powered pan-species computational pathology. Nature communications 14 (1) (2023)
Magnus J Haughey, Aleix Bassolas, Sandro Sousa, Ann-Marie C Baker, Trevor A Graham, Vincenzo Nicosia, Weini Huang
First passage time analysis of spatial mutation patterns reveals sub-clonal evolutionary dynamics in colorectal cancer. PLoS computational biology 19 (3) (2023)
Helen Hockings, Eszter Lakatos, Weini Huang, Maximilian Mossner, Mohammed Ateeb Khan, Stephen Metcalf, Francesco Nicolini, Kane Smith, Ann-Marie C Baker, Trevor A Graham, Michelle Lockley
Adaptive therapy achieves long-term control of chemotherapy resistance in high grade ovarian cancer. bioRxiv : the preprint server for biology (2023)
Qingli Guo, Eszter Lakatos, Ibrahim Al Bakir, Kit Curtius, Trevor A Graham, Ville Mustonen
The mutational signatures of formalin fixation on the human genome. Nature communications 13 (1) (2022)
Timon Heide, Jacob Househam, George D Cresswell, Inmaculada Spiteri, Claire Lynn, Maximilian Mossner, Chris Kimberley, Javier Fernandez-Mateos, Bingjie Chen, Luis Zapata, Chela James, Iros Barozzi, Ketevan Chkhaidze, Daniel Nichol, Vinaya Gunasri, Alison May Berner, Melissa Schmidt, Eszter Lakatos, Ann-Marie C Baker, Helena Costa, Miriam Mitchinson, Rocco Giovanni Piazza, Marnix Jansen, Giulio Caravagna, Daniele Ramazzotti, Darryl Shibata, John A Bridgewater, Manuel Rodriguez, Luca Magnani, Trevor A Graham, Andrea Sottoriva
The co-evolution of the genome and epigenome in colorectal cancer. Nature 611 (7937) (2022)
Calum Gabbutt, Nicholas A Wright, Ann-Marie C Baker, Darryl Shibata, Trevor A Graham
Lineage tracing in human tissues. The Journal of pathology 257 (4) (2022)
Calum Gabbutt, Ryan O Schenck, Daniel J Weisenberger, Christopher Kimberley, Alison Berner, Jacob Househam, Eszter Lakatos, Mark Robertson-Tessi, Isabel Martin, Roshani Patel, Susan K Clark, Andrew Latchford, Christopher P Barnes, Simon J Leedham, Alexander A R A Anderson, Trevor A Graham, Darryl Shibata
Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues. Nature biotechnology 40 (5) (2022)
Jacob Househam, Timon Heide, George D Cresswell, Inmaculada Spiteri, Chris Kimberley, Luis Zapata, Claire Lynn, Chela James, Maximilian Mossner, Javier Fernandez-Mateos, Alessandro Vinceti, Ann-Marie C Baker, Calum Gabbutt, Alison Berner, Melissa Schmidt, Bingjie Chen, Eszter Lakatos, Vinaya Gunasri, Daniel Nichol, Helena Costa, Miriam Mitchinson, Daniele Ramazzotti, Benjamin Werner, Francesco Iorio, Marnix Jansen, Giulio Caravagna, Christopher P Barnes, Darryl Shibata, John A Bridgewater, Manuel Rodriguez, Luca Magnani, Andrea Sottoriva, Trevor A Graham
Phenotypic plasticity and genetic control in colorectal cancer evolution. Nature 611 (7937) (2022)
Chandler D Gatenbee, Ann-Marie C Baker, Ryan O Schenck, Maximilian A R Strobl, Jeffrey West, Margarida P Neves, Sara Yakub Hasan, Eszter Lakatos, Pierre Martinez, William C H Cross, Marnix Jansen, Manuel Rodriguez, Christopher J Whelan, Andrea Sottoriva, Simon Leedham, Mark Robertson-Tessi, Trevor A Graham, Alexander A R A Anderson
Immunosuppressive niche engineering at the onset of human colorectal cancer. Nature communications 13 (1) (2022)
Esha Madan, António M Palma, Vignesh Vudatha, Jose G Trevino, Kedar Nath Natrajan, Robert A Winn, Kyoung Jae Won, Trevor A Graham, Ronny Drapkin, Stuart A C McDonald, Paul B Fisher, Rajan Gogna
Cell competition in carcinogenesis. Cancer research (2022)
Melissa Schmidt, Richard J Hackett, Ann-Marie C Baker, Stuart A C McDonald, Michael Quante, Trevor A Graham
Evolutionary dynamics in Barrett oesophagus: implications for surveillance, risk stratification and therapy. Nature reviews. Gastroenterology & hepatology (2021)
Yannik Bollen, Ellen Stelloo, Petra van Leenen, Myrna van den Bos, Bas Ponsioen, Bingxin Lu, Markus J van Roosmalen, Ana C F Bolhaqueiro, Christopher Kimberley, Maximilian Mossner, William C H Cross, Nicolle J M Besselink, Bastiaan R Van der Roest, Sander Boymans, Koen C Oost, Sippe G de Vries, Holger Rehmann, Edwin Cuppen, Susanne M A Lens, Geert J P L Kops, Wigard P Kloosterman, Leon W M M Terstappen, Christopher P Barnes, Andrea Sottoriva, Trevor A Graham, Hugo J G Snippert
Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns. Nature genetics 53 (8) (2021)
Maximilian Mossner, Ann-Marie C Baker, Trevor A Graham
The role of single-cell sequencing in studying tumour evolution. Faculty reviews 10 (2021)
Mehmet Yalchin, Ann-Marie C Baker, Trevor A Graham, Ailsa Hart
Predicting Colorectal Cancer Occurrence in IBD. Cancers 13 (12) (2021)
Kit Curtius, Misha Kabir, Ibrahim Al Bakir, Chang Ho Ryan Choi, Juanda L Hartono, Michael Johnson, James E East, null null, James O Lindsay, Roser Vega, Siwan Thomas-Gibson, Janindra Warusavitarne, Ana Wilson, Trevor A Graham, Ailsa Hart
Multicentre derivation and validation of a colitis-associated colorectal cancer risk prediction web tool. Gut (2021)
Barbara Lupo, Francesco Sassi, Marika Pinnelli, Francesco Galimi, Eugenia R Zanella, Valentina Vurchio, Giorgia Migliardi, Paolo Armando Gagliardi, Alberto Puliafito, Daria Manganaro, Paolo Luraghi, Michael Kragh, Mikkel W Pedersen, Ivan D Horak, Carla Boccaccio, Enzo Medico, Luca Primo, Daniel Nichol, Inmaculada Spiteri, Timon Heide, Alexandra Vatsiou, Trevor A Graham, Elena Élez, Guillem Argiles, Paolo G Nuciforo, Andrea Sottoriva, Rodrigo Dienstmann, Diego Pasini, Elena Grassi, Claudio Isella, Andrea Bertotti, Livio Trusolino
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype. Science translational medicine 12 (555) (2021)
Trevor A Graham, Darryl Shibata
Navigating the path to distant metastasis. Nature genetics 52 (7) (2020)
Marc J Williams, Luis Zapata, Benjamin Werner, Christopher P Barnes, Andrea Sottoriva, Trevor A Graham
Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios. eLife 9 (2020)
Eszter Lakatos, Marc J Williams, Ryan O Schenck, William C H Cross, Jacob Househam, Luis Zapata, Benjamin Werner, Chandler Gatenbee, Mark Robertson-Tessi, Christopher P Barnes, Alexander A R A Anderson, Andrea Sottoriva, Trevor A Graham
Evolutionary dynamics of neoantigens in growing tumors. Nature genetics 52 (10) (2020)
Inês Sequeira, Mamunur Rashid, Inês M Tomás, Marc J Williams, Trevor A Graham, David J Adams, Alessandra Vigilante, Fiona M Watt
Genomic landscape and clonal architecture of mouse oral squamous cell carcinomas dictate tumour ecology. Nature communications 11 (1) (2020)
Fevzi Demircioglu, Jun Wang, Juliana Candido, Ana S H Costa, Pedro Casado, Beatriz de Luxan Delgado, Louise E Reynolds, Jesus Gomez-Escudero, Emma Newport, Vinothini Rajeeve, Ann-Marie C Baker, Marina Roy-Luzarraga, Trevor A Graham, Julie Foster, Yu Wang, James J Campbell, Rajinder Singh, Penglie Zhang, Thomas J Schall, Frances R Balkwill, Jane Sosabowski, Pedro Rodriguez Cutillas, Christian Frezza, Patricia Sancho, Kairbaan Hodivala-Dilke
Cancer associated fibroblast FAK regulates malignant cell metabolism. Nature communications 11 (1) (2020)
Daniel Temko, Ian P M Tomlinson, Simone Severini, Benjamin Schuster-Boeckler, Trevor A Graham
Author Correction: The effects of mutational processes and selection on driver mutations across cancer types. Nature communications 11 (1) (2020)
Benjamin Werner, Jack Case, Marc J Williams, Ketevan Chkhaidze, Daniel Temko, Javier Fernández-Mateos, George D Cresswell, Daniel Nichol, William Cross, Inmaculada Spiteri, Weini Huang, Ian P M Tomlinson, Christopher P Barnes, Trevor A Graham, Andrea Sottoriva
Measuring single cell divisions in human tissues from multi-region sequencing data. Nature communications 11 (1) (2020)
Giulio Caravagna, Timon Heide, Marc J Williams, Luis Zapata, Daniel Nichol, Ketevan Chkhaidze, William Cross, George D Cresswell, Benjamin Werner, Ahmet Acar, Louis Chesler, Christopher P Barnes, Guido Sanguinetti, Trevor A Graham, Andrea Sottoriva
Subclonal reconstruction of tumors by using machine learning and population genetics. Nature genetics 52 (9) (2020)
Benjamin Werner, Marc J Williams, Christopher P Barnes, Trevor A Graham, Andrea Sottoriva
Reply to 'Currently available bulk sequencing data do not necessarily support a model of neutral tumor evolution'. Nature genetics 50 (12) (2019)
Samra Turajlic, Andrea Sottoriva, Trevor A Graham, Charles Swanton
Resolving genetic heterogeneity in cancer. Nature reviews. Genetics 20 (7) (2019)
Ketevan Chkhaidze, Timon Heide, Benjamin Werner, Marc J Williams, Weini Huang, Giulio Caravagna, Trevor A Graham, Andrea Sottoriva
Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data. PLoS computational biology 15 (7) (2019)
Ann-Marie Baker, Calum Gabbutt, Marc J Williams, Biancastella Cereser, Noor Jawad, Manuel Rodriguez-Justo, Marnix Jansen, Christopher P Barnes, Benjamin D Simons, Stuart Ac McDonald, Trevor A Graham, Nicholas A Wright
Crypt fusion as a homeostatic mechanism in the human colon. Gut 68 (11) (2019)
Marc J Williams, Benjamin Werner, Timon Heide, Christopher P Barnes, Trevor A Graham, Andrea Sottoriva
Reply to 'Revisiting signatures of neutral tumor evolution in the light of complexity of cancer genomic data'. Nature genetics 50 (12) (2019)
Marc J Williams, Benjamin Werner, Chris P Barnes, Trevor A Graham, Andrea Sottoriva
Reply: Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures. Nature genetics 49 (9) (2019)
Daniel E Foxler, Katherine S Bridge, John G Foster, Paul Grevitt, Sean Curry, Kunal M Shah, Kathryn M Davidson, Ai Nagano, Emanuala Gadaleta, Hefin I Rhys, Paul T Kennedy, Miguel A Hermida, Ting-Yu Chang, Peter E Shaw, Louise E Reynolds, Tristan R McKay, Hsei-Wei Wang, Paulo S Ribeiro, Michael J Plevin, Dimitris Lagos, Nicholas R Lemoine, Prabhakar Rajan, Trevor A Graham, Claude Chelala, Kairbaan M Hodivala-Dilke, Ian Spendlove, Tyson V Sharp
A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia. EMBO molecular medicine 10 (8) (2019)
Timon Heide, Angela Maurer, Monika Eipel, Katrin Knoll, Mirja Geelvink, Juergen Veeck, Ruth Knuechel, Julius van Essen, Robert Stoehr, Arndt Hartmann, Janine Altmueller, Trevor A Graham, Nadine Therese Gaisa
Multiregion human bladder cancer sequencing reveals tumour evolution, bladder cancer phenotypes and implications for targeted therapy. The Journal of pathology 248 (2) (2019)
Daniel Temko, Inge C Van Gool, Emily Rayner, Mark Glaire, Seiko Makino, Matthew Brown, Laura Chegwidden, Claire Palles, Jeroen Depreeuw, Andrew D Beggs, Chaido Stathopoulou, John Mason, Ann-Marie Baker, Marc Williams, Vincenzo Cerundolo, Margarida Rei, Jenny C Taylor, Anna Schuh, Ahmed Ahmed, Frédéric Amant, Diether Lambrechts, Vincent Thbm Smit, Tjalling Bosse, Trevor A Graham, David N Church, Ian Tomlinson
Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response. The Journal of pathology 245 (3) (2018)
Pierre Martinez, Diego Mallo, Thomas G Paulson, Xiaohong Li, Carissa A Sanchez, Brian J Reid, Trevor A Graham, Mary K Kuhner, Carlo C Maley
Evolution of Barrett's esophagus through space and time at single-crypt and whole-biopsy levels. Nature communications 9 (1) (2018)
Ann-Marie Baker, William Cross, Kit Curtius, Ibrahim Al Bakir, Chang-Ho Ryan Choi, Hayley Louise Davis, Daniel Temko, Sujata Biswas, Pierre Martinez, Marc J Williams, James O Lindsay, Roger Feakins, Roser Vega, Stephen J Hayes, Ian P M Tomlinson, Stuart A C McDonald, Morgan Moorghen, Andrew Silver, James E East, Nicholas A Wright, Lai Mun Wang, Manuel Rodriguez-Justo, Marnix Jansen, Ailsa L Hart, Simon J Leedham, Trevor A Graham
Evolutionary history of human colitis-associated colorectal cancer. Gut 68 (6) (2018)
Shamzah Araf, Jun Wang, Koorosh Korfi, Celine Pangault, Eleni Kotsiou, Ana Rio-Machin, Tahrima Rahim, James Heward, Andrew James Clear, Sameena Iqbal, Jeff K Davies, Peter Johnson, Maria Calaminici, Silvia Montoto, Rebecca Auer, Claude Chelala, John G Gribben, Trevor A Graham, Thierry Fest, Jude Fitzgibbon, Jessica Okosun
Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma. Leukemia 32 (5) (2018)
William Cross, Michal Kovac, Ville Mustonen, Daniel Temko, Hayley Davis, Ann-Marie Baker, Sujata Biswas, Roland Arnold, Laura Chegwidden, Chandler Gatenbee, Alexander A R A Anderson, Viktor Hendrik Koelzer, Pierre Martinez, Xiaowei Jiang, Enric Domingo, Dan J Woodcock, Yun Feng, Monika Kovacova, Tim Maughan, null null, Marnix Jansen, Manuel Rodriguez-Justo, Shazad Ashraf, Richard Guy, Christopher Cunningham, James E East, David C Wedge, Lai Mun Wang, Claire Palles, Karl Heinimann, Andrea Sottoriva, Simon J Leedham, Trevor A Graham, Ian P M Tomlinson
The evolutionary landscape of colorectal tumorigenesis. Nature ecology & evolution 2 (10) (2018)
Marc J Williams, Benjamin Werner, Timon Heide, Christina Curtis, Christopher P Barnes, Andrea Sottoriva, Trevor A Graham
Quantification of subclonal selection in cancer from bulk sequencing data. Nature genetics 50 (6) (2018)
Giulio Caravagna, Ylenia Giarratano, Daniele Ramazzotti, Ian P M Tomlinson, Trevor A Graham, Guido Sanguinetti, Andrea Sottoriva
Detecting repeated cancer evolution from multi-region tumor sequencing data. Nature methods 15 (9) (2018)
Daniel Temko, Ian P M Tomlinson, Simone Severini, Benjamin Schuster-Boeckler, Trevor A Graham
The effects of mutational processes and selection on driver mutations across cancer types. Nature communications 9 (1) (2018)
Pierre Martinez, Christopher Kimberley, Nicolai J BirkBak, Andrea Marion Marquard, Zoltan Szallasi, Trevor A Graham
Quantification of within-sample genetic heterogeneity from SNP-array data. Scientific reports 7 (1) (2017)
Ruping Sun, Zheng Hu, Andrea Sottoriva, Trevor A Graham, Arbel Harpak, Zhicheng Ma, Jared M Fischer, Darryl Shibata, Christina Curtis
Between-region genetic divergence reflects the mode and tempo of tumor evolution. Nature genetics 49 (7) (2017)
Ann-Marie Baker, Weini Huang, Xiao-Ming Mindy Wang, Marnix Jansen, Xiao-Jun Ma, Jeffrey Kim, Courtney M Anderson, Xingyong Wu, Liuliu Pan, Nan Su, Yuling Luo, Enric Domingo, Timon Heide, Andrea Sottoriva, Annabelle Lewis, Andrew D Beggs, Nicholas A Wright, Manuel Rodriguez-Justo, Emily Park, Ian P M Tomlinson, Trevor A Graham
Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution. Nature communications 8 (1) (2017)
William Ch Cross, Trevor A Graham, Nicholas A Wright
New paradigms in clonal evolution: punctuated equilibrium in cancer. The Journal of pathology 240 (2) (2016)
Pierre Martinez, Margriet R Timmer, Chiu T Lau, Silvia Calpe, Maria Del Carmen Sancho-Serra, Danielle Straub, Ann-Marie Baker, Sybren L Meijer, Fiebo J W Ten Kate, Rosalie C Mallant-Hent, Anton H J Naber, Arnoud H A M van Oijen, Lubbertus C Baak, Pieter Scholten, Clarisse J M Böhmer, Paul Fockens, Jacques J G H M Bergman, Carlo C Maley, Trevor A Graham, Kausilia K Krishnadath
Dynamic clonal equilibrium and predetermined cancer risk in Barrett's oesophagus. Nature communications 7 (2016)
Trevor A Graham, Andrea Sottoriva
Measuring cancer evolution from the genome. The Journal of pathology 241 (2) (2016)
John M Findlay, Francesc Castro Giner, Seiko Makino, Emily Rayner, Christiana Kartsonaki, William Cross, Michal Kovac, Danny Ulahannan, Claire Palles, Richard S Gillies, Thomas P MacGregor, David Church, Nicholas D Maynard, Francesca M Buffa, Jean-Baptiste Cazier, Trevor A Graham, Lai-Mun Wang, Ricky A Sharma, Mark Middleton, Ian P M Tomlinson
Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy. Nature communications 7 (2016)
Noemi Andor, Trevor A Graham, Marnix Jansen, Li Charlie Xia, C Athena Aktipis, Claudia Petritsch, Hanlee P Ji, Carlo C Maley
Pan-cancer analysis of the extent and consequences of intratumor heterogeneity. Nature medicine 22 (1) (2015)
Andrea Sottoriva, Haeyoun Kang, Zhicheng Ma, Trevor A Graham, Matthew P Salomon, Junsong Zhao, Paul Marjoram, Kimberly Siegmund, Michael F Press, Darryl Shibata, Christina Curtis
A Big Bang model of human colorectal tumor growth. Nature genetics 47 (3) (2015)

Trevor A Graham.css-eqlu8i{font-size:small;padding-left:4px;} (Trevor Graham)

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Trevor A Graham (Trevor Graham)