Characterization of diet-dependent temporal changes in circulating short-chain fatty acid concentrations: A randomized crossover dietary trial.
Jerusa BrignardelloSofia FountanaJoram Matthias PosmaEdward S ChambersJeremy K NicholsonJulien WistGary S FrostIsabel Garcia-PerezElaine HolmesPublished in: The American journal of clinical nutrition (2022)
The GC-MS method allowed robust mapping of diurnal patterns in SCFA concentrations, which were affected by diet, and highlighted the importance of standardizing the timing of SCFA measurements in dietary studies. This trial was registered on the NIHR UK clinical trial gateway and with ISRCTN as ISRCTN43087333.