Effect of a Probiotic Preparation on Ventilator-Associated Pneumonia in Critically Ill Patients Admitted to the Intensive Care Unit: A Prospective Double-Blind Randomized Controlled Trial.

Ata MahmoodpoorHadi HamishehkarRoghaieh AsghariRamin AbriKamran ShadvarSarvin Sanaie

Published in: Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition (2018)

The results of probiotic administration for the prevention of VAP remain inconclusive in this trial. However, such an approach can decrease the length of ICU and hospital stay. Well-designed multicenter clinical studies with defined combinations of probiotics and definite end points are necessary in this field.

Keyphrases

study protocol
double blind
randomized controlled trial
phase iii
clinical trial
placebo controlled
phase ii
bacillus subtilis
intensive care unit
lactic acid
open label
healthcare
mechanical ventilation
adverse drug
cross sectional
molecularly imprinted
high resolution
emergency department
respiratory failure