The Relationship between Fatty Acids and the Development, Course and Treatment of Rheumatoid Arthritis.
Wojciech TańskiNatalia ŚwiątoniowskaMateusz TabinBeata Jankowska-PolańskaPublished in: Nutrients (2022)
For this systematic review, a search of the relevant literature was conducted in the EMBASE and PubMed databases. We used the following terms: 'rheumatoid arthritis' in conjunction with 'fatty acid'. The following inclusion criteria had to be satisfied for the studies to be included in the analysis: an RCT/observational/cohort study published in English. A total of seventy-one studies were analysed. The presented systematic review of the available data indicates that increased consumption of omega-3 fatty acids (FAs) may have a beneficial effect on human health by decreasing pain and disease activity in patients with RA. The beneficial effect of unsaturated FA on the clinical parameters of RA was demonstrated in all 71 studies analysed. The content of omega-3 FAs in the diet and the consumption of fish, which are their main source, may contribute to a reduced incidence of RA. FAs are an essential component in the synthesis of eicosanoids that exhibit anti-inflammatory properties. Due to the documented positive influence of unsaturated FAs on treatment outcomes, the use of a diet rich in long-chain unsaturated FAs should be the standard of care, along with pharmacotherapy, in the treatment of RA patients. An important element in the control of the treatment process should be the routine assessment of the quality of life of RA patients.
Keyphrases
- rheumatoid arthritis
- disease activity
- systematic review
- fatty acid
- ankylosing spondylitis
- systemic lupus erythematosus
- end stage renal disease
- rheumatoid arthritis patients
- human health
- newly diagnosed
- ejection fraction
- chronic kidney disease
- meta analyses
- risk assessment
- interstitial lung disease
- chronic pain
- peritoneal dialysis
- juvenile idiopathic arthritis
- randomized controlled trial
- anti inflammatory
- palliative care
- pain management
- climate change
- spinal cord
- neuropathic pain
- spinal cord injury
- artificial intelligence