Liver Metastatic Breast Cancer: Epidemiology, Dietary Interventions, and Related Metabolism.
Qian-Ying ZuoNicole Hwajin ParkJenna Kathryn LeeZeynep Madak ErdoganPublished in: Nutrients (2022)
The median overall survival of patients with metastatic breast cancer is only 2-3 years, and for patients with untreated liver metastasis, it is as short as 4-8 months. Improving the survival of women with breast cancer requires more effective anti-cancer strategies, especially for metastatic disease. Nutrients can influence tumor microenvironments, and cancer metabolism can be manipulated via a dietary modification to enhance anti-cancer strategies. Yet, there are no standard evidence-based recommendations for diet therapies before or during cancer treatment, and few studies provide definitive data that certain diets can mediate tumor progression or therapeutic effectiveness in human cancer. This review focuses on metastatic breast cancer, in particular liver metastatic forms, and recent studies on the impact of diets on disease progression and treatment.
Keyphrases
- metastatic breast cancer
- papillary thyroid
- weight loss
- squamous cell carcinoma
- small cell lung cancer
- physical activity
- squamous cell
- endothelial cells
- systematic review
- randomized controlled trial
- poor prognosis
- free survival
- case control
- electronic health record
- risk factors
- heavy metals
- induced pluripotent stem cells
- big data
- locally advanced
- combination therapy
- data analysis
- smoking cessation
- pluripotent stem cells