Lifestyle intervention in individuals with impaired glucose regulation affects Caveolin-1 expression and DNA methylation.
Helene Aparecida FachimKirk SiddalsNagaraj MalipatilRachelle P DonnGabriela Yc MorenoCaroline F DaltonSafwaan AdamHandrean SoranJ Martin GibsonAdrian H HealdPublished in: Adipocyte (2021)
Our findings suggest a role for CAV1 in modulating adipocyte function as a consequence of lifestyle changes, as exercises and diet. These results may provide insights into new therapeutic targets for diabetes prevention.
Keyphrases
- weight loss
- physical activity
- dna methylation
- cardiovascular disease
- metabolic syndrome
- poor prognosis
- glycemic control
- type diabetes
- randomized controlled trial
- adipose tissue
- insulin resistance
- gene expression
- genome wide
- blood glucose
- signaling pathway
- fatty acid
- resistance training
- long non coding rna
- binding protein
- body composition
- blood pressure