A Questionnaire-based Study Exploring Participant Perspectives in a Perinatal Human Challenge Trial.
James H J BevanAnastasia A TheodosiouJames CornerRobert B DoreyRobert Charles ReadChristine Elizabeth JonesPublished in: The Pediatric infectious disease journal (2023)
The successful completion of the Lactamica 9 study demonstrates that human challenge research in healthy pregnant women can be acceptable and feasible. Participants' initial concerns of potential discomfort were outweighed by predominantly altruistic motivations and perception of the intervention as "natural."