Tactile sensitivity and motor coordination in infancy: Effect of age, prior surgery, anaesthesia & critical illness.
Laura CornelissenEllen UnderwoodLaurel J Gabard-DurnamMelissa SotoAlice J TaoKimberly LoboTakao K HenschCharles B BerdePublished in: PloS one (2022)
This brief sensory testing protocol may reliably measure tactile and nociceptive reactivity in human infants. Age predicts nociceptive threshold which likely reflects ongoing maturation of spinal and supraspinal circuits. Prior hospital experience has a negligible global effect on sensory processing demonstrating the resilience of the CNS in adverse environments.
Keyphrases
- neuropathic pain
- endothelial cells
- minimally invasive
- spinal cord
- healthcare
- randomized controlled trial
- adverse drug
- coronary artery bypass
- climate change
- blood brain barrier
- induced pluripotent stem cells
- social support
- pluripotent stem cells
- weight gain
- acute coronary syndrome
- acute care
- surgical site infection
- depressive symptoms
- weight loss
- electronic health record