Combined Transcriptome and Circulating Tumor DNA Longitudinal Biomarker Analysis Associates With Clinical Outcomes in Advanced Solid Tumors Treated With Pembrolizumab.
Alberto Hernando-CalvoS Y Cindy YangMaria Vila-CasadesúsMing HanZhihui Amy LiuA Hal K BermanAnna SpreaficoAlbiruni Abdul RazakStéphanie LheureuxAaron Richard HansenDeborah Lo GiaccoFarnoosh Abbas-AghababazadehJudith MatitoBenjamin Haibe-KainsTrevor J PughScott V BratmanMeenakshi MalhotraRoger BercheOmar SaavedraElena GarraldaSawako ElstonLillian L SiuPamela S OhashiAna VivancosPhilippe L BedardPublished in: JCO precision oncology (2024)
Our data indicate that the addition of ΔctDNA to baseline VIGex may refine prediction for IO.