Bicuspid Aortic Valve-Associated Regulatory Regions Reveal GATA4 Regulation and Function During Human-Induced Pluripotent Stem Cell-Based Endothelial-Mesenchymal Transition-Brief Report.
Tingting HuangJiaxi ChengHao FengWei ZhouPing QiuDong ZhouDongshan YangJifeng ZhangCristen J WillerYuqing Eugene ChenY Eugene ChenBo YangPublished in: Arteriosclerosis, thrombosis, and vascular biology (2022)
expression during hiPSC-based EndoMT, which in turn promotes EndoMT progression, implicating its contribution to heart valve development.
Keyphrases
- aortic valve
- stem cells
- aortic stenosis
- endothelial cells
- high glucose
- transcatheter aortic valve replacement
- aortic valve replacement
- transcatheter aortic valve implantation
- transcription factor
- poor prognosis
- diabetic rats
- heart failure
- bone marrow
- genome wide
- induced pluripotent stem cells
- sensitive detection
- pluripotent stem cells
- single cell
- ejection fraction
- living cells
- cell therapy
- oxidative stress
- mesenchymal stem cells
- fluorescent probe
- gene expression
- drug induced
- mitral valve