Yuqing Eugene Chen (Y Eugene Chen)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 37

Top Topics

Aortic Aneurysm

Top Venues

Science translational medicine

Arteriosclerosis, thrombosis, and vascular biology

Nature communications

Signal transduction and targeted therapy

This page only lists publications with an associated author ORCID identifier.

Publications

Ying Yang, Hao Feng, Ying Tang, Zhenguo Wang, Ping Qiu, Xihua Huang, Lin Chang, Jifeng Zhang, Yuqing Eugene Chen, Y Eugene Chen, Bo Yang
Bioengineered vascular grafts with a pathogenic TGFBR1 variant model aneurysm formation in vivo and reveal underlying collagen defects. Science translational medicine 16 (746) (2024)
Lu Fang, Changjie Liu, Zong-Zhe Jiang, Mengxiao Wang, Kang Geng, Yangkai Xu, Yujie Zhu, Yiwen Fu, Jing Xue, Wenxin Shan, Qi Zhang, Jie Chen, Jiahong Chen, Mingming Zhao, Yuxuan Guo, K W Michael Siu, Yuqing Eugene Chen, Yong Xu, Donghui Liu, Lemin Zheng
Annexin A1 binds PDZ and LIM domain 7 to inhibit adipogenesis and prevent obesity. Signal transduction and targeted therapy 9 (1) (2024)
Linkang Zhou, Xiaoxue Qiu, Ziyi Meng, Tongyu Liu, Zhimin Chen, Peng Zhang, Henry Kuang, Tong Pan, You Lu, Ling Qi, David P Olson, X Z Shawn Xu, Yuqing Eugene Chen, Siming Li, Jiandie D Lin
Hepatic danger signaling triggers TREM2 + macrophage induction and drives steatohepatitis via MS4A7-dependent inflammasome activation. Science translational medicine 16 (738) (2024)
Ying Yang, Hao Feng, Ying Tang, Zhenguo Wang, Ping Qiu, Xihua Huang, Lin Chang, Jifeng Zhang, Yuqing Eugene Chen, Y Eugene Chen, Bo Yang
Bioengineered vascular grafts with a pathogenic TGFBR1 variant model aneurysm formation in vivo and reveal underlying collagen defects. Science translational medicine 16 (746) (2024)
Ying Yang, Hao Feng, Ying Tang, Zhenguo Wang, Ping Qiu, Xihua Huang, Lin Chang, Jifeng Zhang, Yuqing Eugene Chen, Y Eugene Chen, Bo Yang
Bioengineered vascular grafts with a pathogenic TGFBR1 variant model aneurysm formation in vivo and reveal underlying collagen defects. Science translational medicine 16 (746) (2024)
Ying Yang, Hao Feng, Ying Tang, Zhenguo Wang, Ping Qiu, Xihua Huang, Lin Chang, Jifeng Zhang, Yuqing Eugene Chen, Y Eugene Chen, Bo Yang
Bioengineered vascular grafts with a pathogenic TGFBR1 variant model aneurysm formation in vivo and reveal underlying collagen defects. Science translational medicine 16 (746) (2024)
Linkang Zhou, Xiaoxue Qiu, Ziyi Meng, Tongyu Liu, Zhimin Chen, Peng Zhang, Henry Kuang, Tong Pan, You Lu, Ling Qi, David P Olson, X Z Shawn Xu, Yuqing Eugene Chen, Siming Li, Jiandie D Lin
Hepatic danger signaling triggers TREM2 + macrophage induction and drives steatohepatitis via MS4A7-dependent inflammasome activation. Science translational medicine 16 (738) (2024)
Lu Fang, Changjie Liu, Zong-Zhe Jiang, Mengxiao Wang, Kang Geng, Yangkai Xu, Yujie Zhu, Yiwen Fu, Jing Xue, Wenxin Shan, Qi Zhang, Jie Chen, Jiahong Chen, Mingming Zhao, Yuxuan Guo, K W Michael Siu, Yuqing Eugene Chen, Yong Xu, Donghui Liu, Lemin Zheng
Annexin A1 binds PDZ and LIM domain 7 to inhibit adipogenesis and prevent obesity. Signal transduction and targeted therapy 9 (1) (2024)
Linkang Zhou, Xiaoxue Qiu, Ziyi Meng, Tongyu Liu, Zhimin Chen, Peng Zhang, Henry Kuang, Tong Pan, You Lu, Ling Qi, David P Olson, X Z Shawn Xu, Yuqing Eugene Chen, Siming Li, Jiandie D Lin
Hepatic danger signaling triggers TREM2 + macrophage induction and drives steatohepatitis via MS4A7-dependent inflammasome activation. Science translational medicine 16 (738) (2024)
Lu Fang, Changjie Liu, Zong-Zhe Jiang, Mengxiao Wang, Kang Geng, Yangkai Xu, Yujie Zhu, Yiwen Fu, Jing Xue, Wenxin Shan, Qi Zhang, Jie Chen, Jiahong Chen, Mingming Zhao, Yuxuan Guo, K W Michael Siu, Yuqing Eugene Chen, Yong Xu, Donghui Liu, Lemin Zheng
Annexin A1 binds PDZ and LIM domain 7 to inhibit adipogenesis and prevent obesity. Signal transduction and targeted therapy 9 (1) (2024)
Y Eugene Chen, Yang Zhao, Hao Feng, Jane Macaulay, Ying Tang, Zain Sultan, Guizhen Zhao, Yanhong Guo, Jifeng Zhang, Bo Yang, Yuqing Eugene Chen
Single-Molecule Spatial Transcriptomics of Human Thoracic Aortic Aneurysms Uncovers Calcification-Related CARTPT -Expressing Smooth Muscle Cells. Arteriosclerosis, thrombosis, and vascular biology (2023)
Kemao Xiu, Jifeng Zhang, Jie Xu, Yuqing Eugene Chen, Peter X Ma
Recent progress in polymeric gene vectors: Delivery mechanisms, molecular designs, and applications. Biophysics reviews 4 (1) (2023)
Ienglam Lei, Wei Huang, Pierre Emmanuel Noly, Suyash Naik, Miriyam Ghali, Liu Liu, Francis D Pagani, Ashraf Abou El Ela, Jordan S Pober, Bertram Pitt, Jeffrey L Platt, Marilia Cascalho, Zhong Wang, Yuqing Eugene Chen, Richard M Mortensen, Paul C Tang
Metabolic reprogramming by immune-responsive gene 1 up-regulation improves donor heart preservation and function. Science translational medicine 15 (682) (2023)
Ienglam Lei, Wei Huang, Pierre Emmanuel Noly, Suyash Naik, Miriyam Ghali, Liu Liu, Francis D Pagani, Ashraf Abou El Ela, Jordan S Pober, Bertram Pitt, Jeffrey L Platt, Marilia Cascalho, Zhong Wang, Yuqing Eugene Chen, Richard M Mortensen, Paul C Tang
Metabolic reprogramming by immune-responsive gene 1 up-regulation improves donor heart preservation and function. Science translational medicine 15 (682) (2023)
Ienglam Lei, Wei Huang, Pierre Emmanuel Noly, Suyash Naik, Miriyam Ghali, Liu Liu, Francis D Pagani, Ashraf Abou El Ela, Jordan S Pober, Bertram Pitt, Jeffrey L Platt, Marilia Cascalho, Zhong Wang, Yuqing Eugene Chen, Richard M Mortensen, Paul C Tang
Metabolic reprogramming by immune-responsive gene 1 up-regulation improves donor heart preservation and function. Science translational medicine 15 (682) (2023)
Ienglam Lei, Wei Huang, Pierre Emmanuel Noly, Suyash Naik, Miriyam Ghali, Liu Liu, Francis D Pagani, Ashraf Abou El Ela, Jordan S Pober, Bertram Pitt, Jeffrey L Platt, Marilia Cascalho, Zhong Wang, Yuqing Eugene Chen, Richard M Mortensen, Paul C Tang
Metabolic reprogramming by immune-responsive gene 1 up-regulation improves donor heart preservation and function. Science translational medicine 15 (682) (2023)
Jiahuan Chen, Huanyu Zhang, Linquan Li, Xinwei Zhang, Dazhong Zhao, Lingyu Wang, Jiaqi Wang, Ping Yang, Huan Sun, Kun Liu, Weiwei Chen, Lin Li, Feng Lin, Zhanjun Li, Yuqing Eugene Chen, Jifeng Zhang, Daxin Pang, Hongsheng Ouyang, Yuquan He, Jianglin Fan, Xiaochun Tang
Lp-PLA 2 (Lipoprotein-Associated Phospholipase A 2 ) Deficiency Lowers Cholesterol Levels and Protects Against Atherosclerosis in Rabbits. Arteriosclerosis, thrombosis, and vascular biology (2022)
Tingting Huang, Jiaxi Cheng, Hao Feng, Wei Zhou, Ping Qiu, Dong Zhou, Dongshan Yang, Jifeng Zhang, Cristen J Willer, Yuqing Eugene Chen, Y Eugene Chen, Bo Yang
Bicuspid Aortic Valve-Associated Regulatory Regions Reveal GATA4 Regulation and Function During Human-Induced Pluripotent Stem Cell-Based Endothelial-Mesenchymal Transition-Brief Report. Arteriosclerosis, thrombosis, and vascular biology 43 (2) (2022)
Tingting Huang, Jiaxi Cheng, Hao Feng, Wei Zhou, Ping Qiu, Dong Zhou, Dongshan Yang, Jifeng Zhang, Cristen J Willer, Yuqing Eugene Chen, Y Eugene Chen, Bo Yang
Bicuspid Aortic Valve-Associated Regulatory Regions Reveal GATA4 Regulation and Function During Human-Induced Pluripotent Stem Cell-Based Endothelial-Mesenchymal Transition-Brief Report. Arteriosclerosis, thrombosis, and vascular biology 43 (2) (2022)
Tingting Huang, Jiaxi Cheng, Hao Feng, Wei Zhou, Ping Qiu, Dong Zhou, Dongshan Yang, Jifeng Zhang, Cristen J Willer, Yuqing Eugene Chen, Y Eugene Chen, Bo Yang
Bicuspid Aortic Valve-Associated Regulatory Regions Reveal GATA4 Regulation and Function During Human-Induced Pluripotent Stem Cell-Based Endothelial-Mesenchymal Transition-Brief Report. Arteriosclerosis, thrombosis, and vascular biology 43 (2) (2022)
Tingting Huang, Jiaxi Cheng, Hao Feng, Wei Zhou, Ping Qiu, Dong Zhou, Dongshan Yang, Jifeng Zhang, Cristen J Willer, Yuqing Eugene Chen, Y Eugene Chen, Bo Yang
Bicuspid Aortic Valve-Associated Regulatory Regions Reveal GATA4 Regulation and Function During Human-Induced Pluripotent Stem Cell-Based Endothelial-Mesenchymal Transition. Arteriosclerosis, thrombosis, and vascular biology (2022)
Tingting Huang, Jiaxi Cheng, Hao Feng, Wei Zhou, Ping Qiu, Dong Zhou, Dongshan Yang, Jifeng Zhang, Cristen J Willer, Yuqing Eugene Chen, Y Eugene Chen, Bo Yang
Bicuspid Aortic Valve-Associated Regulatory Regions Reveal GATA4 Regulation and Function During Human-Induced Pluripotent Stem Cell-Based Endothelial-Mesenchymal Transition-Brief Report. Arteriosclerosis, thrombosis, and vascular biology 43 (2) (2022)
Tingting Huang, Jiaxi Cheng, Hao Feng, Wei Zhou, Ping Qiu, Dong Zhou, Dongshan Yang, Jifeng Zhang, Cristen J Willer, Yuqing Eugene Chen, Y Eugene Chen, Bo Yang
Bicuspid Aortic Valve-Associated Regulatory Regions Reveal GATA4 Regulation and Function During Human-Induced Pluripotent Stem Cell-Based Endothelial-Mesenchymal Transition-Brief Report. Arteriosclerosis, thrombosis, and vascular biology 43 (2) (2022)
Dandan Wang, Bilian Yu, Qingrun Li, Yanhong Guo, Tomonari Koike, Yui Koike, Qingqing Wu, Jifeng Zhang, Ling Mao, Xiaoyu Tang, Liang Sun, Xu Lin, Jiarui Wu, Yuqing Eugene Chen, Daoquan Peng, Rong Zeng
HDL quality features revealed by proteome‒lipidome connectivity are associated with atherosclerotic disease. Journal of molecular cell biology 14 (3) (2022)
Karl A Nath, Raman Deep Singh, Anthony J Croatt, Allan W Ackerman, Joseph P Grande, Khasayarsha Khazaie, Yuqing Eugene Chen, Jifeng Zhang
KLF11 Is a Novel Endogenous Protectant against Renal Ischemia-Reperfusion Injury. Kidney360 3 (8) (2022)
Xiangfeng Lu, Zhongying Liu, Qingmei Cui, Fangchao Liu, Jianxin Li, Xiaoge Niu, Chong Shen, Dongsheng Hu, Keyong Huang, Jichun Chen, Xiaolong Xing, Yingxin Zhao, Fanghong Lu, Xiaoqing Liu, Jie Cao, Shufeng Chen, HongXia Ma, Ling Yu, Xianping Wu, Xigui Wu, Ying Li, Huan Zhang, Xingbo Mo, Liancheng Zhao, Jianfeng Huang, Laiyuan Wang, Wanqing Wen, Christina E Bailey, Fumihiko Takeuchi, Woon Puay Koh, E Shyong Tai, Ching-Yu Cheng, Tien-Yin Wong, Xuling Chang, Mark Yan-Yee Chan, Wei Gao, Hong Zheng, Kexin Chen, Jing Chen, Jiang He, Clara Sze Man Tang, Karen Siu-Ling Lam, Hung Fat Tse, Chloe Yu Yan Cheung, Atsushi Takahashi, Michiaki Kubo, Norihiro Kato, Chikashi C Terao, Yoichiro Kamatani, Pak Chung Sham, Chew-Kiat Heng, Zhibin Hu, Yuqing Eugene Chen, Tangchun Wu, Hongbing Shen, Cristen J Willer, Dongfeng Gu
A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study. European heart journal 43 (18) (2022)
Mingming Zhao, Haoran Wei, Chenze Li, Rui Zhan, Changjie Liu, Jianing Gao, Yaodong Yi, Xiao Cui, Wenxin Shan, Liang Ji, Bing Pan, Si Cheng, Moshi Song, Haipeng Sun, Huidi Jiang, Jun Cai, Minerva T Garcia-Barrio, Yuqing Eugene Chen, Xiangbao Meng, Erdan Dong, Dao-Wen Wang, Lemin Zheng
Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy. Nature communications 13 (1) (2022)
Haocheng Lu, Wa Du, Lu Ren, Milton H Hamblin, Richard C Becker, Yuqing Eugene Chen, Yanbo Fan
Vascular Smooth Muscle Cells in Aortic Aneurysm: From Genetics to Mechanisms. Journal of the American Heart Association (2021)
Yonghong Luo, Haocheng Lu, Daoquan Peng, Xiangbo Ruan, Yuqing Eugene Chen, Yanhong Guo
Liver-humanized mice: A translational strategy to study metabolic disorders. Journal of cellular physiology (2021)
Jun Zhou, Zhuoying Ren, Jie Xu, Jifeng Zhang, Yuqing Eugene Chen
Gene editing therapy ready for cardiovascular diseases: opportunities, challenges, and perspectives. Medical review (Berlin, Germany) 1 (1) (2021)
Haocheng Lu, Jifeng Zhang, Yuqing Eugene Chen, Minerva T Garcia-Barrio
Integration of Transformative Platforms for the Discovery of Causative Genes in Cardiovascular Diseases. Cardiovascular drugs and therapy 35 (3) (2021)
Oren Rom, Yuhao Liu, Zhipeng Liu, Ying Zhao, Jianfeng Wu, Alia Ghrayeb, Luis Villacorta, Yanbo Fan, Lin Chang, Lu Wang, Cai Liu, Dongshan Yang, Jun Song, Jason C Rech, Yanhong Guo, Huilun Wang, Guizhen Zhao, Wenying Liang, Ying Yu, Haocheng Lu, Tomonari Koike, Tony Hayek, Subramaniam Pennathur, Chuanwu Xi, Bo Wen, Duxin Sun, Minerva T Garcia-Barrio, Michael Aviram, Eyal Gottlieb, Inbal Mor, Wanqing Liu, Jifeng Zhang, Yuqing Eugene Chen
Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome. Science translational medicine 12 (572) (2021)
Pengfei Sun, Nitin Kumar, Adrienne Tin, Jing Zhao, Michael R Brown, Zesen Lin, Min-Lee Yang, Qiwen Zheng, Jia Jia, Lawrence F Bielak, Bing Yu, Eric Boerwinkle, Kristina L Hunker, Josef Coresh, Yuqing Eugene Chen, Yong Huo, Sharon L R Kardia, Rami Khoriaty, Xiang Zhou, Alanna C Morrison, Yan Zhang, Santhi K Ganesh
Epidemiologic and Genetic Associations of Erythropoietin With Blood Pressure, Hypertension, and Coronary Artery Disease. Hypertension (Dallas, Tex. : 1979) 78 (5) (2021)
Yajie Chen, Ahmed Bilal Waqar, Kazutoshi Nishijima, Bo Ning, Shuji Kitajima, Fumikazu Matsuhisa, Lu Chen, Enqi Liu, Tomonari Koike, Ying Yu, Jifeng Zhang, Yuqing Eugene Chen, Huijun Sun, Jingyan Liang, Jianglin Fan
Macrophage-derived MMP-9 enhances the progression of atherosclerotic lesions and vascular calcification in transgenic rabbits. Journal of cellular and molecular medicine 24 (7) (2020)
Jonas Bille Nielsen, Oren Rom, Ida Surakka, Sarah E Graham, Wei Zhou, Tanmoy Roychowdhury, Lars G Fritsche, Sarah A Gagliano Taliun, Carlo Sidore, Yuhao Liu, Maiken E Gabrielsen, Anne Heidi Skogholt, Brooke N Wolford, William Overton, Ying Zhao, Jin Chen, He Zhang, Whitney E Hornsby, Akua Acheampong, Austen Grooms, Amanda Schaefer, Gregory J M Zajac, Luis Villacorta, Jifeng Zhang, Ben Michael Brumpton, Mari Løset, Vivek Rai, Pia Rengtved Lundegaard, Morten Salling Olesen, Kent D Taylor, Nicholette D D Allred, Yii-Der Chen, Seung H Choi, Steven A Lubitz, Patrick T Ellinor, Kathleen C Barnes, Michelle Daya, Nicholas Rafaels, Scott T Weiss, Jessica Lasky-Su, Russell P Tracy, Ramachandran S Vasan, L Adrienne Cupples, Rasika A Mathias, Lisa R Yanek, Lewis C Becker, Patricia A Peyser, Lawrence F Bielak, Jennifer A Smith, Stella Aslibekyan, Bertha A Hidalgo, Donna K Arnett, Marguerite R Irvin, James G Wilson, Solomon K Musani, Adolfo Correa, Stephen S Rich, Xiuqing Guo, Jerome I Rotter, Barbara A Konkle, Jill M Johnsen, Allison Elizabeth Ashley-Koch, Marilyn J Telen, Vivien A Sheehan, John E Blangero, Joanne E Curran, Juan M Peralta, Courtney Montgomery, Wayne H-H Sheu, Ren-Hua Chung, Karen Schwander, Seyed M Nouraie, Victor R Gordeuk, Yingze Zhang, Charles Kooperberg, Alexander P Reiner, Rebecca D Jackson, Eugene R Bleecker, Deborah A Meyers, Xingnan Li, Sayantan Das, Ketian Yu, Jonathon LeFaive, Albert Vernon Smith, Tom Blackwell, Daniel Taliun, Sebastian Zollner, Lukas Forer, Sebastian Schoenherr, Christian Fuchsberger, Anita Pandit, Matthew Zawistowski, Sachin Kheterpal, Chad M Brummett, Pradeep Natarajan, David Schlessinger, Seunggeun Lee, Hyun Min Kang, Francesco Cucca, Oddgeir L Holmen, Bjørn Olav Åsvold, Michael Boehnke, Sekar Kathiresan, Gonçalo R Abecasis, Yuqing Eugene Chen, Cristen J Willer, Kristian Hveem
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease. Nature communications 11 (1) (2020)
Linyuan Ma, Jinxue Ruan, Jun Song, Luan Wen, Dongshan Yang, Jiang-Yang Zhao, Xiaofeng Xia, Yuqing Eugene Chen, Jifeng Zhang, Jie Xu
MiCas9 increases large size gene knock-in rates and reduces undesirable on-target and off-target indel edits. Nature communications 11 (1) (2020)
Congzhen Qiao, Shengdi Li, Haocheng Lu, Fan Meng, Yanbo Fan, Yanhong Guo, Yuqing Eugene Chen, Jifeng Zhang
Laminar Flow Attenuates Macrophage Migration Inhibitory Factor Expression in Endothelial Cells. Scientific reports 8 (1) (2018)