The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors.
Stephen P H AlexanderArthur ChristopoulosAnthony P DavenportEamonn KellyAlistair A MathieJohn A PetersEmma L VealeJane F ArmstrongElena FaccendaSimon D HardingJamie A DaviesMaria Pia AbbracchioGeorge AbrahamAlexander AgoulnikWayne AlexanderKhaled Al-HosainiMagnus BäckJillian G BakerNicholas M BarnesRoss A D BathgateJean-Martin BeaulieuAnnette G Beck-SickingerMaik BehrensKenneth E BernsteinBernhard BettlerNigel J M BirdsallVictoria A BlahoFrancois BoulayCorinne BousquetHans Bräuner-OsborneGeoffrey BurnstockGirolamo CalóJusto P CastañoKevin J CattStefania CerutiPaul L ChazotNan ChiangBice ChiniJerold ChunAntonia CianciulliOlivier CivelliLucie H ClappRéjean CoutureHelen M CoxZsolt CsabaClaes DahlgrenGordon DentSteven D DouglasPascal DournaudSatoru EguchiEmanuel EscherEdward J FilardoTung FongMarta FumagalliRaul R GainetdinovMichael L GareljaMarc de GasparoCraig GerardMarvin GershengornFernand GobeilTheodore L GoodfriendCyril GoudetLukas GrätzKaren J GregoryAndrew L GundlachJörg HamannJulien HansonRichard L HaugerDebbie L HayAkos HeinemannDeron Raymond HerrMorley D HollenbergNicholas D HollidayMastgugu HoriuchiDaniel HoyerLászló HunyadyAhsan HusainAdriaan P IJzermanTadashi InagamiKenneth A JacobsonRobert T JensenRalf JockersDeepa JonnalagaddaSadashiva S KarnikKlemens KaupmannJacqueline KempCharles KennedyHirotaka MizunoTakio KitazawaPawel KozielewiczHans-Jürgen KreienkampJyrki P KukkonenTobias LangenhanDan LarhammarKatie LeachDavide LeccaJohn D LeeSusan E LeemanJérôme LeprinceXaria X LiStephen J LolaitAmelie LuppRobyn MacraeJanet J MaguireDavide MalfaciniJean MazellaCraig A McArdleShlomo MelmedMartin Christian MichelLaurence J MillerVincenzo MitoloBernard MouillacChrista Elisabeth MüllerPhilip M MurphyJean-Louis NahonTony NgoXavier NorelDuuamene NyimanuAnne-Marie O'CarrollStefan OffermannsMaria Antonietta PanaroMarc ParmentierRoger G PertweeJean-Philippe PinEric R ProssnitzMark QuinnRithwik RamachandranManisha RayRainer K ReinscheidPhilippe RondardGianenrico RovatiChiara RuzzaGareth John SangerTorsten SchönebergGunnar SchulteStefan SchulzDeborah L SegaloffCharles N SerhanKhuraijam Dhanachandra SinghCraig M SmithLeigh A StoddartYukihiko SugimotoRoger J SummersValerie P TanDavid M ThalWalter Wally ThomasPieter B M W M TimmermansKalyan TirupulaLawrence TollGiovanni TulipanoHamiyet UnalThomas UngerCeline ValantPatrick VanderheydenDavid VaudryHubert VaudryJean-Pierre VilardagaChristopher S WalkerJi Ming WangDonald T WardHans-Jürgen WesterGary B WillarsTom Lloyd WilliamsTrent M WoodruffChengcan YaoRichard D YePublished in: British journal of pharmacology (2023)
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (https://www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.16177. G protein-coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.