Jean-Philippe Pin

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 50

Top Venues

Nature communications

Journal of medicinal chemistry

Science advances

eLife

CNRS Délégation Languedoc-Roussillon

Université des Sciences et des Technologies du Languedoc (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

CNRS Délégation Languedoc-Roussillon Jan 01 2011

France

Director :: Institute of Functional Genomics

Education History

Université des Sciences et des Technologies du Languedoc Sep 01 1984 - Oct 01 1987

France

PHD

Ecole Normale Supérieure, rue d'Ulm Sep 01 1981 - Aug 31 1985

France

MSC

Publications

Chanjuan Xu, Yiwei Zhou, Yuxuan Liu, Li Lin, Peng Liu, Xiaomei Wang, Zhengyuan Xu, Jean-Philippe Pin, Philippe Rondard, Jianfeng Liu
Specific pharmacological and G i/o protein responses of some native GPCRs in neurons. Nature communications 15 (1) (2024)
Na Liu, Floriane Eshak, Fanny Malhaire, Isabelle Brabet, Laurent Prézeau, Emma Renard, Jean-Philippe Pin, Francine C Acher, Markus Staudt, Lennart Bunch
Design, Synthesis, Pharmacology, and In Silico Studies of (1 S ,2 S ,3 S )-2-(( S )-Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu 2 Receptor Agonist. Journal of medicinal chemistry 67 (2) (2024)
Clémentine Eva Philibert, Candice Disdier, Pierre-André Lafon, Alexandre Bouyssou, Mathieu Oosterlaken, Sonya Galant, Anne Pizzoccaro, Pola Tuduri, Jeanne Ster, Jianfeng Liu, Julie Kniazeff, Jean-Philippe Pin, Philippe Rondard, Philippe Marin, Franck Vandermoere
TrkB receptor interacts with mGlu 2 receptor and mediates antipsychotic-like effects of mGlu 2 receptor activation in the mouse. Science advances 10 (4) (2024)
Chanjuan Xu, Yiwei Zhou, Yuxuan Liu, Li Lin, Peng Liu, Xiaomei Wang, Zhengyuan Xu, Jean-Philippe Pin, Philippe Rondard, Jianfeng Liu
Specific pharmacological and G i/o protein responses of some native GPCRs in neurons. Nature communications 15 (1) (2024)
Na Liu, Floriane Eshak, Fanny Malhaire, Isabelle Brabet, Laurent Prézeau, Emma Renard, Jean-Philippe Pin, Francine C Acher, Markus Staudt, Lennart Bunch
Design, Synthesis, Pharmacology, and In Silico Studies of (1 S ,2 S ,3 S )-2-(( S )-Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu 2 Receptor Agonist. Journal of medicinal chemistry 67 (2) (2024)
Nunzia Cristiano, Alexandre Cabayé, Isabelle Brabet, Ralf Glatthar, Amelie Tora, Cyril Goudet, Hugues-Olivier Bertrand, Anne Goupil-Lamy, Peter J Flor, Jean-Philippe Pin, Isabelle McCort-Tranchepain, Francine C Acher
Novel Inhibitory Site Revealed by XAP044 Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain. Journal of medicinal chemistry (2024)
Shumin Ma, Xueliang Yin, Jean-Philippe Pin, Philippe Rondard, Ping Yi, Jianfeng Liu
Absence of calcium-sensing receptor basal activity due to inter-subunit disulfide bridges. Communications biology 7 (1) (2024)
Clémentine Eva Philibert, Candice Disdier, Pierre-André Lafon, Alexandre Bouyssou, Mathieu Oosterlaken, Sonya Galant, Anne Pizzoccaro, Pola Tuduri, Jeanne Ster, Jianfeng Liu, Julie Kniazeff, Jean-Philippe Pin, Philippe Rondard, Philippe Marin, Franck Vandermoere
TrkB receptor interacts with mGlu 2 receptor and mediates antipsychotic-like effects of mGlu 2 receptor activation in the mouse. Science advances 10 (4) (2024)
Chanjuan Xu, Yiwei Zhou, Yuxuan Liu, Li Lin, Peng Liu, Xiaomei Wang, Zhengyuan Xu, Jean-Philippe Pin, Philippe Rondard, Jianfeng Liu
Specific pharmacological and G i/o protein responses of some native GPCRs in neurons. Nature communications 15 (1) (2024)
Floriane Eshak, Léo Pion, Pauline Scholler, Damien Nevoltris, Patrick Chames, Philippe Rondard, Jean-Philippe Pin, Francine C Acher, Anne Goupil-Lamy
Epitope Identification of an mGlu5 Receptor Nanobody Using Physics-Based Molecular Modeling and Deep Learning Techniques. Journal of chemical information and modeling (2024)
Shumin Ma, Xueliang Yin, Jean-Philippe Pin, Philippe Rondard, Ping Yi, Jianfeng Liu
Absence of calcium-sensing receptor basal activity due to inter-subunit disulfide bridges. Communications biology 7 (1) (2024)
Nunzia Cristiano, Alexandre Cabayé, Isabelle Brabet, Ralf Glatthar, Amelie Tora, Cyril Goudet, Hugues-Olivier Bertrand, Anne Goupil-Lamy, Peter J Flor, Jean-Philippe Pin, Isabelle McCort-Tranchepain, Francine C Acher
Novel Inhibitory Site Revealed by XAP044 Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain. Journal of medicinal chemistry 67 (14) (2024)
Floriane Eshak, Léo Pion, Pauline Scholler, Damien Nevoltris, Patrick Chames, Philippe Rondard, Jean-Philippe Pin, Francine C Acher, Anne Goupil-Lamy
Epitope Identification of an mGlu5 Receptor Nanobody Using Physics-Based Molecular Modeling and Deep Learning Techniques. Journal of chemical information and modeling 64 (11) (2024)
Chanjuan Xu, Yiwei Zhou, Yuxuan Liu, Li Lin, Peng Liu, Xiaomei Wang, Zhengyuan Xu, Jean-Philippe Pin, Philippe Rondard, Jianfeng Liu
Specific pharmacological and G i/o protein responses of some native GPCRs in neurons. Nature communications 15 (1) (2024)
Nunzia Cristiano, Alexandre Cabayé, Isabelle Brabet, Ralf Glatthar, Amelie Tora, Cyril Goudet, Hugues-Olivier Bertrand, Anne Goupil-Lamy, Peter J Flor, Jean-Philippe Pin, Isabelle McCort-Tranchepain, Francine C Acher
Novel Inhibitory Site Revealed by XAP044 Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain. Journal of medicinal chemistry 67 (14) (2024)
Clémentine Eva Philibert, Candice Disdier, Pierre-André Lafon, Alexandre Bouyssou, Mathieu Oosterlaken, Sonya Galant, Anne Pizzoccaro, Pola Tuduri, Jeanne Ster, Jianfeng Liu, Julie Kniazeff, Jean-Philippe Pin, Philippe Rondard, Philippe Marin, Franck Vandermoere
TrkB receptor interacts with mGlu 2 receptor and mediates antipsychotic-like effects of mGlu 2 receptor activation in the mouse. Science advances 10 (4) (2024)
Nunzia Cristiano, Alexandre Cabayé, Isabelle Brabet, Ralf Glatthar, Amelie Tora, Cyril Goudet, Hugues-Olivier Bertrand, Anne Goupil-Lamy, Peter J Flor, Jean-Philippe Pin, Isabelle McCort-Tranchepain, Francine C Acher
Novel Inhibitory Site Revealed by XAP044 Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain. Journal of medicinal chemistry 67 (14) (2024)
Chanjuan Xu, Yiwei Zhou, Yuxuan Liu, Li Lin, Peng Liu, Xiaomei Wang, Zhengyuan Xu, Jean-Philippe Pin, Philippe Rondard, Jianfeng Liu
Specific pharmacological and G i/o protein responses of some native GPCRs in neurons. Nature communications 15 (1) (2024)
Na Liu, Floriane Eshak, Fanny Malhaire, Isabelle Brabet, Laurent Prézeau, Emma Renard, Jean-Philippe Pin, Francine C Acher, Markus Staudt, Lennart Bunch
Design, Synthesis, Pharmacology, and In Silico Studies of (1 S ,2 S ,3 S )-2-(( S )-Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu 2 Receptor Agonist. Journal of medicinal chemistry (2024)
Shumin Ma, Xueliang Yin, Jean-Philippe Pin, Philippe Rondard, Ping Yi, Jianfeng Liu
Absence of calcium-sensing receptor basal activity due to inter-subunit disulfide bridges. Communications biology 7 (1) (2024)
Stephen P H Alexander, Arthur Christopoulos, Anthony P Davenport, Eamonn Kelly, Alistair A Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Jamie A Davies, Maria Pia Abbracchio, George Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al-Hosaini, Magnus Bäck, Jillian G Baker, Nicholas M Barnes, Ross A D Bathgate, Jean-Martin Beaulieu, Annette G Beck-Sickinger, Maik Behrens, Kenneth E Bernstein, Bernhard Bettler, Nigel J M Birdsall, Victoria A Blaho, Francois Boulay, Corinne Bousquet, Hans Bräuner-Osborne, Geoffrey Burnstock, Girolamo Caló, Justo P Castaño, Kevin J Catt, Stefania Ceruti, Paul L Chazot, Nan Chiang, Bice Chini, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H Clapp, Réjean Couture, Helen M Cox, Zsolt Csaba, Claes Dahlgren, Gordon Dent, Steven D Douglas, Pascal Dournaud, Satoru Eguchi, Emanuel Escher, Edward J Filardo, Tung Fong, Marta Fumagalli, Raul R Gainetdinov, Michael L Garelja, Marc de Gasparo, Craig Gerard, Marvin Gershengorn, Fernand Gobeil, Theodore L Goodfriend, Cyril Goudet, Lukas Grätz, Karen J Gregory, Andrew L Gundlach, Jörg Hamann, Julien Hanson, Richard L Hauger, Debbie L Hay, Akos Heinemann, Deron Raymond Herr, Morley D Hollenberg, Nicholas D Holliday, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P IJzerman, Tadashi Inagami, Kenneth A Jacobson, Robert T Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva S Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Hirotaka Mizuno, Takio Kitazawa, Pawel Kozielewicz, Hans-Jürgen Kreienkamp, Jyrki P Kukkonen, Tobias Langenhan, Dan Larhammar, Katie Leach, Davide Lecca, John D Lee, Susan E Leeman, Jérôme Leprince, Xaria X Li, Stephen J Lolait, Amelie Lupp, Robyn Macrae, Janet J Maguire, Davide Malfacini, Jean Mazella, Craig A McArdle, Shlomo Melmed, Martin Christian Michel, Laurence J Miller, Vincenzo Mitolo, Bernard Mouillac, Christa Elisabeth Müller, Philip M Murphy, Jean-Louis Nahon, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne-Marie O'Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Roger G Pertwee, Jean-Philippe Pin, Eric R Prossnitz, Mark Quinn, Rithwik Ramachandran, Manisha Ray, Rainer K Reinscheid, Philippe Rondard, Gianenrico Rovati, Chiara Ruzza, Gareth John Sanger, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L Segaloff, Charles N Serhan, Khuraijam Dhanachandra Singh, Craig M Smith, Leigh A Stoddart, Yukihiko Sugimoto, Roger J Summers, Valerie P Tan, David M Thal, Walter Wally Thomas, Pieter B M W M Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Jean-Pierre Vilardaga, Christopher S Walker, Ji Ming Wang, Donald T Ward, Hans-Jürgen Wester, Gary B Willars, Tom Lloyd Williams, Trent M Woodruff, Chengcan Yao, Richard D Ye
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors. British journal of pharmacology (2023)
Stephen P H Alexander, Arthur Christopoulos, Anthony P Davenport, Eamonn Kelly, Alistair A Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Jamie A Davies, Maria Pia Abbracchio, George Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al-Hosaini, Magnus Bäck, Jillian G Baker, Nicholas M Barnes, Ross A D Bathgate, Jean-Martin Beaulieu, Annette G Beck-Sickinger, Maik Behrens, Kenneth E Bernstein, Bernhard Bettler, Nigel J M Birdsall, Victoria A Blaho, Francois Boulay, Corinne Bousquet, Hans Bräuner-Osborne, Geoffrey Burnstock, Girolamo Caló, Justo P Castaño, Kevin J Catt, Stefania Ceruti, Paul L Chazot, Nan Chiang, Bice Chini, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H Clapp, Réjean Couture, Helen M Cox, Zsolt Csaba, Claes Dahlgren, Gordon Dent, Steven D Douglas, Pascal Dournaud, Satoru Eguchi, Emanuel Escher, Edward J Filardo, Tung Fong, Marta Fumagalli, Raul R Gainetdinov, Michael L Garelja, Marc de Gasparo, Craig Gerard, Marvin Gershengorn, Fernand Gobeil, Theodore L Goodfriend, Cyril Goudet, Lukas Grätz, Karen J Gregory, Andrew L Gundlach, Jörg Hamann, Julien Hanson, Richard L Hauger, Debbie L Hay, Akos Heinemann, Deron Raymond Herr, Morley D Hollenberg, Nicholas D Holliday, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P IJzerman, Tadashi Inagami, Kenneth A Jacobson, Robert T Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva S Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Hirotaka Mizuno, Takio Kitazawa, Pawel Kozielewicz, Hans-Jürgen Kreienkamp, Jyrki P Kukkonen, Tobias Langenhan, Dan Larhammar, Katie Leach, Davide Lecca, John D Lee, Susan E Leeman, Jérôme Leprince, Xaria X Li, Stephen J Lolait, Amelie Lupp, Robyn Macrae, Janet J Maguire, Davide Malfacini, Jean Mazella, Craig A McArdle, Shlomo Melmed, Martin Christian Michel, Laurence J Miller, Vincenzo Mitolo, Bernard Mouillac, Christa Elisabeth Müller, Philip M Murphy, Jean-Louis Nahon, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne-Marie O'Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Roger G Pertwee, Jean-Philippe Pin, Eric R Prossnitz, Mark Quinn, Rithwik Ramachandran, Manisha Ray, Rainer K Reinscheid, Philippe Rondard, Gianenrico Rovati, Chiara Ruzza, Gareth John Sanger, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L Segaloff, Charles N Serhan, Khuraijam Dhanachandra Singh, Craig M Smith, Leigh A Stoddart, Yukihiko Sugimoto, Roger J Summers, Valerie P Tan, David M Thal, Walter Wally Thomas, Pieter B M W M Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Jean-Pierre Vilardaga, Christopher S Walker, Ji Ming Wang, Donald T Ward, Hans-Jürgen Wester, Gary B Willars, Tom Lloyd Williams, Trent M Woodruff, Chengcan Yao, Richard D Ye
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors. British journal of pharmacology (2023)
Nathalie Lecat-Guillet, Robert B Quast, Hongkang Liu, Emmanuel Bourrier, Thor C Møller, Xavier Rovira, Stéphanie Soldevila, Laurent Lamarque, Eric Trinquet, Jianfeng Liu, Jean-Philippe Pin, Philippe Rondard, Emmanuel Margeat
Concerted conformational changes control metabotropic glutamate receptor activity. Science advances 9 (22) (2023)
Jordi Haubrich, Jurriaan M Zwier, Fabienne Charrier-Savournin, Laurent Prezeau, Jean-Philippe Pin
Different EGF-induced receptor dimer conformations for signaling and internalization. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 38 (1) (2023)
Stephen P H Alexander, Arthur Christopoulos, Anthony P Davenport, Eamonn Kelly, Alistair A Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Jamie A Davies, Maria Pia Abbracchio, George Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al-Hosaini, Magnus Bäck, Jillian G Baker, Nicholas M Barnes, Ross A D Bathgate, Jean-Martin Beaulieu, Annette G Beck-Sickinger, Maik Behrens, Kenneth E Bernstein, Bernhard Bettler, Nigel J M Birdsall, Victoria A Blaho, Francois Boulay, Corinne Bousquet, Hans Bräuner-Osborne, Geoffrey Burnstock, Girolamo Caló, Justo P Castaño, Kevin J Catt, Stefania Ceruti, Paul L Chazot, Nan Chiang, Bice Chini, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H Clapp, Réjean Couture, Helen M Cox, Zsolt Csaba, Claes Dahlgren, Gordon Dent, Steven D Douglas, Pascal Dournaud, Satoru Eguchi, Emanuel Escher, Edward J Filardo, Tung Fong, Marta Fumagalli, Raul R Gainetdinov, Michael L Garelja, Marc de Gasparo, Craig Gerard, Marvin Gershengorn, Fernand Gobeil, Theodore L Goodfriend, Cyril Goudet, Lukas Grätz, Karen J Gregory, Andrew L Gundlach, Jörg Hamann, Julien Hanson, Richard L Hauger, Debbie L Hay, Akos Heinemann, Deron Raymond Herr, Morley D Hollenberg, Nicholas D Holliday, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P IJzerman, Tadashi Inagami, Kenneth A Jacobson, Robert T Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva S Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Hirotaka Mizuno, Takio Kitazawa, Pawel Kozielewicz, Hans-Jürgen Kreienkamp, Jyrki P Kukkonen, Tobias Langenhan, Dan Larhammar, Katie Leach, Davide Lecca, John D Lee, Susan E Leeman, Jérôme Leprince, Xaria X Li, Stephen J Lolait, Amelie Lupp, Robyn Macrae, Janet J Maguire, Davide Malfacini, Jean Mazella, Craig A McArdle, Shlomo Melmed, Martin Christian Michel, Laurence J Miller, Vincenzo Mitolo, Bernard Mouillac, Christa Elisabeth Müller, Philip M Murphy, Jean-Louis Nahon, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne-Marie O'Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Roger G Pertwee, Jean-Philippe Pin, Eric R Prossnitz, Mark Quinn, Rithwik Ramachandran, Manisha Ray, Rainer K Reinscheid, Philippe Rondard, Gianenrico Rovati, Chiara Ruzza, Gareth John Sanger, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L Segaloff, Charles N Serhan, Khuraijam Dhanachandra Singh, Craig M Smith, Leigh A Stoddart, Yukihiko Sugimoto, Roger J Summers, Valerie P Tan, David M Thal, Walter Wally Thomas, Pieter B M W M Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Jean-Pierre Vilardaga, Christopher S Walker, Ji Ming Wang, Donald T Ward, Hans-Jürgen Wester, Gary B Willars, Tom Lloyd Williams, Trent M Woodruff, Chengcan Yao, Richard D Ye
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors. British journal of pharmacology (2023)
Jordi Haubrich, Jurriaan M Zwier, Fabienne Charrier-Savournin, Laurent Prezeau, Jean-Philippe Pin
Different EGF-induced receptor dimer conformations for signaling and internalization. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 38 (1) (2023)
Jordi Haubrich, Jurriaan M Zwier, Fabienne Charrier-Savournin, Laurent Prezeau, Jean-Philippe Pin
Different EGF-induced receptor dimer conformations for signaling and internalization. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 38 (1) (2023)
Jordi Haubrich, Jurriaan M Zwier, Fabienne Charrier-Savournin, Laurent Prezeau, Jean-Philippe Pin
Different EGF-induced receptor dimer conformations for signaling and internalization. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 38 (1) (2023)
Jiyong Meng, Chanjuan Xu, Pierre-André Lafon, Salomé Roux, Michaël Mathieu, Rui Zhou, Pauline Scholler, Emilie Blanc, Jérôme A J Becker, Julie Le Merrer, Javier González-Maeso, Patrick Chames, Jianfeng Liu, Jean-Philippe Pin, Philippe Rondard
Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain. Nature chemical biology 18 (8) (2022)
Matej Gazdarica, Judith Noda, Oleh Durydivka, Vendula Novosadova, Ken Mackie, Jean-Philippe Pin, Laurent Prezeau, Jaroslav Blahos
SGIP1 modulates kinetics and interactions of the cannabinoid receptor 1 and G protein-coupled receptor kinase 3 signalosome. Journal of neurochemistry 160 (6) (2022)
Wei Fang, Fan Yang, Chanjuan Xu, Shenglong Ling, Li Lin, Yingxin Zhou, Wenjing Sun, Xiaomei Wang, Peng Liu, Philippe Rondard, Pan Shi, Jean-Philippe Pin, Changlin Tian, Jianfeng Liu
Structural basis of the activation of metabotropic glutamate receptor 3. Cell research 32 (7) (2022)
Junke Liu, Hengmin Tang, Chanjuan Xu, Shengnan Zhou, Xunying Zhu, Yuanyuan Li, Laurent Prézeau, Tao Xu, Jean-Philippe Pin, Philippe Rondard, Wei Ji, Jianfeng Liu
Biased signaling due to oligomerization of the G protein-coupled platelet-activating factor receptor. Nature communications 13 (1) (2022)
Cécile Derieux, Audrey Léauté, Agathe Brugoux, Déborah Jaccaz, Claire Terrier, Jean-Philippe Pin, Julie Kniazeff, Julie Le Merrer, Jerome A J Becker
Chronic sodium bromide treatment relieves autistic-like behavioral deficits in three mouse models of autism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 47 (9) (2022)
Stephen P H Alexander, Arthur Christopoulos, Anthony P Davenport, Eamonn Kelly, Alistair A Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Christopher Southan, Jamie A Davies, Maria Pia Abbracchio, Wayne Alexander, Khaled Al-Hosaini, Magnus Bäck, Nicholas M Barnes, Ross A D Bathgate, Jean-Martin Beaulieu, Kenneth E Bernstein, Bernhard Bettler, Nigel J M Birdsall, Victoria A Blaho, Francois Boulay, Corinne Bousquet, Hans Bräuner-Osborne, Geoffrey Burnstock, Girolamo Caló, Justo P Castaño, Kevin J Catt, Stefania Ceruti, Paul L Chazot, Nan Chiang, Bice Chini, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H Clapp, Réjean Couture, Zsolt Csaba, Claes Dahlgren, Gordon Dent, Khuraijam Dhanachandra Singh, Steven D Douglas, Pascal Dournaud, Satoru Eguchi, Emanuel Escher, Edward J Filardo, Tung Fong, Marta Fumagalli, Raul R Gainetdinov, Marc de Gasparo, Craig Gerard, Marvin Gershengorn, Fernand Gobeil, Theodore L Goodfriend, Cyril Goudet, Karen J Gregory, Andrew L Gundlach, Jörg Hamann, Julien Hanson, Richard L Hauger, Debbie L Hay, Akos Heinemann, Morley D Hollenberg, Nicholas D Holliday, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P IJzerman, Tadashi Inagami, Kenneth A Jacobson, Robert T Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva S Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Hirotaka Mizuno, Takio Kitazawa, Pawel Kozielewicz, Hans-Jürgen Kreienkamp, Jyrki P Kukkonen, Tobias Langenhan, Katie Leach, Davide Lecca, John D Lee, Susan E Leeman, Jérôme Leprince, Xaria X Li, Tom Lloyd Williams, Stephen J Lolait, Amelie Lupp, Robyn Macrae, Janet J Maguire, Jean Mazella, Craig A McArdle, Shlomo Melmed, Martin Christian Michel, Laurence J Miller, Vincenzo Mitolo, Bernard Mouillac, Christa Elisabeth Müller, Philip Murphy, Jean-Louis Nahon, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne-Marie O'Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Roger G Pertwee, Jean-Philippe Pin, Eric R Prossnitz, Mark Quinn, Rithwik Ramachandran, Manisha Ray, Rainer K Reinscheid, Philippe Rondard, Gianenrico Rovati, Chiara Ruzza, Gareth John Sanger, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L Segaloff, Charles N Serhan, Leigh A Stoddart, Yukihiko Sugimoto, Roger J Summers, Valerie P Tan, David M Thal, Walter Wally Thomas, Pieter B M W M Timmermans, Kalyan Tirupula, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Jean-Pierre Vilardaga, Christopher S Walker, Ji Ming Wang, Donald T Ward, Hans-Jürgen Wester, Gary B Willars, Trent M Woodruff, Chengcan Yao, Richard D Ye
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors. British journal of pharmacology (2021)
Cangsong Shen, Chunyou Mao, Chanjuan Xu, Nan Jin, Huibing Zhang, Dan-Dan Shen, Qingya Shen, Xiaomei Wang, Tingjun Hou, Zhong Chen, Philippe Rondard, Jean-Philippe Pin, Yan Zhang, Jianfeng Liu
Structural basis of GABAB receptor-Gi protein coupling. Nature 594 (7864) (2021)
Jordi Haubrich, Joan Font, Robert B Quast, Anne Goupil-Lamy, Pauline Scholler, Damien Nevoltris, Francine C Acher, Patrick Chames, Philippe Rondard, Laurent Prézeau, Jean-Philippe Pin
A nanobody activating metabotropic glutamate receptor 4 discriminates between homo- and heterodimers. Proceedings of the National Academy of Sciences of the United States of America 118 (33) (2021)
Anne-Marinette Cao, Robert B Quast, Fataneh Fatemi, Philippe Rondard, Jean-Philippe Pin, Emmanuel Margeat
Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state. Nature communications 12 (1) (2021)
Juan Du, Dejian Wang, Hongcheng Fan, Chanjuan Xu, Linhua Tai, Shuling Lin, Shuo Han, Qiuxiang Tan, Xinwei Wang, Tuo Xu, Hui Zhang, Xiaojing Chu, Cuiying Yi, Peng Liu, Xiaomei Wang, Yu Zhou, Jean-Philippe Pin, Philippe Rondard, Hong Liu, Jianfeng Liu, Fei Sun, Beili Wu, Qiang Zhao
Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature 594 (7864) (2021)
Yunyun Wang, Siyu Gai, Wenhua Zhang, Xuetao Huang, Shumin Ma, Yujia Huo, Yichen Wu, Haijun Tu, Jean-Philippe Pin, Philippe Rondard, Chanjuan Xu, Jianfeng Liu
The GABAB receptor mediates neuroprotection by coupling to G13. Science signaling 14 (705) (2021)
Hongkang Liu, Ping Yi, Wenjing Zhao, Yuling Wu, Francine C Acher, Jean-Philippe Pin, Jianfeng Liu, Philippe Rondard
Illuminating the allosteric modulation of the calcium-sensing receptor. Proceedings of the National Academy of Sciences of the United States of America 117 (35) (2020)
Hamidreza Shaye, Andrii V Ishchenko, Jordy Homing Lam, Gye Won Han, Li Xue, Philippe Rondard, Jean-Philippe Pin, Vsevolod Katritch, Cornelius Gati, Vadim Cherezov
Structural basis of the activation of a metabotropic GABA receptor. Nature 584 (7820) (2020)
Li Xue, Qian Sun, Han Zhao, Xavier Rovira, Siyu Gai, Qianwen He, Jean-Philippe Pin, Jianfeng Liu, Philippe Rondard
Rearrangement of the transmembrane domain interfaces associated with the activation of a GPCR hetero-oligomer. Nature communications 10 (1) (2019)
Thor C Møller, Jerome Hottin, Caroline Clerté, Jurriaan M Zwier, Thierry Durroux, Philippe Rondard, Laurent Prézeau, Catherine A Royer, Jean-Philippe Pin, Emmanuel Margeat, Julie Kniazeff
Oligomerization of a G protein-coupled receptor in neurons controlled by its structural dynamics. Scientific reports 8 (1) (2018)
Joan Font, Marc López-Cano, Serena Notartomaso, Pamela Scarselli, Paola Di Prieto, Roger Bresoli-Obach, Giuseppe Battaglia, Fanny Malhaire, Xavier Rovira, Juanlo Catena, Jesus Giraldo, Jean-Philippe Pin, Víctor Fernández-Dueñas, Cyril Goudet, Santi Nonell, Ferdinando Nicoletti, Amadeu Llebaria, Francisco Ciruela
Correction: Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator. eLife 7 (2018)
Cyril Rivat, Chamroeun Sar, Ilana Mechaly, Jean-Philippe Leyris, Lucie Diouloufet, Corinne Sonrier, Yann Philipson, Olivier Lucas, Sylvie Mallié, Antoine Jouvenel, Adrien Tassou, Henri Haton, Stéphanie Venteo, Jean-Philippe Pin, Eric Trinquet, Fabienne Charrier-Savournin, Alexandre Mezghrani, Willy Joly, Julie Mion, Martine Schmitt, Alexandre Pattyn, Frédéric Marmigère, Pierre Sokoloff, Patrick Carroll, Didier Rognan, Jean Valmier
Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice. Nature communications 9 (1) (2018)
Chady Nasrallah, Karine Rottier, Romain Marcellin, Vincent Compan, Joan Font, Amadeu Llebaria, Jean-Philippe Pin, Jean-Louis Banères, Guillaume Lebon
Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and Gs. Scientific reports 8 (1) (2018)
Joan Font, Marc López-Cano, Serena Notartomaso, Pamela Scarselli, Paola Di Pietro, Roger Bresoli-Obach, Giuseppe Battaglia, Fanny Malhaire, Xavier Rovira, Juanlo Catena, Jesus Giraldo, Jean-Philippe Pin, Víctor Fernández-Dueñas, Cyril Goudet, Santi Nonell, Ferdinando Nicoletti, Amadeu Llebaria, Francisco Ciruela
Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator. eLife 6 (2017)
Junke Liu, Zongyong Zhang, David Moreno-Delgado, James A R Dalton, Xavier Rovira, Ana Trapero, Cyril Goudet, Amadeu Llebaria, Jesus Giraldo, Qilin Yuan, Philippe Rondard, Siluo Huang, Jianfeng Liu, Jean-Philippe Pin
Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer. eLife 6 (2017)
David Moreno Delgado, Thor C Møller, Jeanne Ster, Jesus Giraldo, Damien Maurel, Xavier Rovira, Pauline Scholler, Jurriaan M Zwier, Julie Perroy, Thierry Durroux, Eric Trinquet, Laurent Prezeau, Philippe Rondard, Jean-Philippe Pin
Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells. eLife 6 (2017)
Pauline Scholler, Damien Nevoltris, Dimitri de Bundel, Simon Bossi, David Moreno-Delgado, Xavier Rovira, Thor C Møller, Driss El Moustaine, Michaël Mathieu, Emilie Blanc, Heather McLean, Elodie Dupuis, Gérard Mathis, Eric Trinquet, Hervé Daniel, Emmanuel Valjent, Daniel Baty, Patrick Chames, Philippe Rondard, Jean-Philippe Pin
Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation. Nature communications 8 (1) (2017)

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Jean-Philippe Pin