Ribosomal protein control of hematopoietic stem cell transformation through direct, non-canonical regulation of metabolism.

Bryan HarrisDinesh K SinghMonika VermaShawn P FahlMichele RhodesShanna R SprinkleMinshi WangYong ZhangJaqueline PerrigoueRachel KesselSuraj PeriJoshua WestOrsi GiriczJacqueline BoultwoodAndrea PellagattiK H RameshCristina MontagnaKith PradhanJeffrey W TynerBrian K KennedyMichael A HolinstatUlrich SteidlStephen SykesAmit VermaDavid L Wiest

Published in: bioRxiv : the preprint server for biology (2023)

Rpl22 controls the function and transformation potential of hematopoietic stem cells through effects on ALOX12 expression, a regulator of fatty acid oxidation.

Keyphrases

hematopoietic stem cell
stem cells
fatty acid
poor prognosis
binding protein
bone marrow
hydrogen peroxide
transcription factor
protein protein
cell therapy
long non coding rna
climate change
risk assessment
visible light