Michael A Holinstat (Michael Holinstat)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 40

Top Venues

Blood

Nature communications

Pharmacology research & perspectives

Science advances

University of Michigan

University of Illinois at Chicago (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Michigan Apr 01 2015

United States

Associate Professor :: Pharmacology

Thomas Jefferson University Oct 01 2008 - Mar 31 2015

United States

Assistant/Associate Professor :: Medicine, Cardeza Foundation for Hematologic Research

Vanderbilt University School of Medicine Oct 01 2008 - Feb 01 2009

United States

Visiting Assistant Professor :: Pharmacology

Education History

University of Illinois at Chicago Jul 01 2000 - Sep 01 2005

United States

PHD :: Pharmacology

Southern Connecticut State University Sep 01 2002 - May 21 2005

United States

BSC :: Biology

University of Illinois at Chicago Jul 01 1998 - May 21 2000

United States

MSC :: Biological Sciences

Publications

Merav Belenkovich, Ruth Veksler, Yevgeniy Kreinin, Tirosh Mekler, Mariane Flores, Josué Sznitman, Michael A Holinstat, Netanel Korin
Clot Accumulation in 3D Microfluidic Bifurcating Microvasculature Network. Micromachines 15 (8) (2024)
Alison L Banka, M Valentina Guevara, Emma R Brannon, Nhien Q Nguyen, Shuang Song, Gillian Cady, David J Pinsky, Kathryn E Uhrich, Reheman Adili, Michael A Holinstat, Omolola Eniola-Adefeso
Cargo-free particles divert neutrophil-platelet aggregates to reduce thromboinflammation. Nature communications 14 (1) (2023)
Jesse I Mobbs, Katrina A Black, Michelle Tran, Wessel A C Burger, Hariprasad Venugopal, Theodore R Holman, Michael A Holinstat, David M Thal, Alisa Glukhova
Cryo-EM structures of human arachidonate 12S-Lipoxygenase (12-LOX) bound to endogenous and exogenous inhibitors. Blood (2023)
Sriganesh B Sharma, William James Melvin, Christopher O Audu, Monica Bame, Nicole M Rhoads, Weisheng Wu, Yogendra Kanthi, Christian Lood, Reheman Adili, Michael A Holinstat, Thomas W Wakefield, Peter K Henke, Bethany B Moore, Katherine Ann Gallagher, Andrea Tara Obi
The histone methyltransferase MLL1/KMT2A in monocytes drives coronavirus-associated coagulopathy and inflammation. Blood 141 (7) (2023)
Adriana Yamaguchi, Christopher van Hoorebeke, Benjamin E Tourdot, Steven C Perry, Grace Lee, Nicole M Rhoads, Andrew Rickenberg, Abigail R Green, James Sorrentino, Jennifer Yeung, J Cody Freedman, Theodore R Holman, Michael A Holinstat
Fatty acids negatively regulate platelet function through formation of noncanonical 15-lipoxygenase-derived eicosanoids. Pharmacology research & perspectives 11 (1) (2023)
Hannah J Larsen, Daire Byrne, Tahsin Özpolat, Aastha Chauhan, S Lawrence Bailey, Nicole M Rhoads, Franklin Reed, Massiel C Stolla, Reheman Adili, Michael A Holinstat, Xiaoyun Fu, Moritz Stolla
Loss of 12-Lipoxygenase Improves the Post-Transfusion Function of Stored Platelets. Arteriosclerosis, thrombosis, and vascular biology (2023)
Sriganesh B Sharma, William James Melvin, Christopher O Audu, Monica Bame, Nicole M Rhoads, Weisheng Wu, Yogendra Kanthi, Christian Lood, Reheman Adili, Michael A Holinstat, Thomas W Wakefield, Peter K Henke, Bethany B Moore, Katherine Ann Gallagher, Andrea Tara Obi
The histone methyltransferase MLL1/KMT2A in monocytes drives coronavirus-associated coagulopathy and inflammation. Blood 141 (7) (2023)
Stephanie A Renna, Xuefei Zhao, Satya P Kunapuli, Peisong Ma, Michael A Holinstat, Matthew B Boxer, David J Maloney, James V Michael, Steven E McKenzie
Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition. Arteriosclerosis, thrombosis, and vascular biology (2023)
Chanel C La, Stephanie A Smith, Sreeparna Vappala, Reheman Adili, Catherine E Luke, Srinivas Abbina, Haiming D Luo, Irina Chafeeva, Matthew Drayton, Louise A Creagh, María de Guadalupe Jaraquemada-Peláez, Nicole M Rhoads, Manu Thomas Kalathottukaren, Peter K Henke, Suzana K Straus, Caigan Du, Edward M Conway, Michael A Holinstat, Charles A Haynes, James H Morrissey, Jayachandran N Kizhakkedathu
Smart thrombosis inhibitors without bleeding side effects via charge tunable ligand design. Nature communications 14 (1) (2023)
Sriganesh B Sharma, William James Melvin, Christopher O Audu, Monica Bame, Nicole M Rhoads, Weisheng Wu, Yogendra Kanthi, Christian Lood, Reheman Adili, Michael A Holinstat, Thomas W Wakefield, Peter K Henke, Bethany B Moore, Katherine Ann Gallagher, Andrea Tara Obi
The histone methyltransferase MLL1/KMT2A in monocytes drives coronavirus-associated coagulopathy and inflammation. Blood 141 (7) (2023)
Adriana Yamaguchi, Christopher van Hoorebeke, Benjamin E Tourdot, Steven C Perry, Grace Lee, Nicole M Rhoads, Andrew Rickenberg, Abigail R Green, James Sorrentino, Jennifer Yeung, J Cody Freedman, Theodore R Holman, Michael A Holinstat
Fatty acids negatively regulate platelet function through formation of noncanonical 15-lipoxygenase-derived eicosanoids. Pharmacology research & perspectives 11 (1) (2023)
Sriganesh B Sharma, William James Melvin, Christopher O Audu, Monica Bame, Nicole M Rhoads, Weisheng Wu, Yogendra Kanthi, Christian Lood, Reheman Adili, Michael A Holinstat, Thomas W Wakefield, Peter K Henke, Bethany B Moore, Katherine Ann Gallagher, Andrea Tara Obi
The histone methyltransferase MLL1/KMT2A in monocytes drives coronavirus-associated coagulopathy and inflammation. Blood 141 (7) (2023)
Michelle Tran, Kevin Yang, Alisa Glukhova, Michael A Holinstat, Theodore R Holman
Inhibitory Investigations of Acyl-CoA Derivatives against Human Lipoxygenase Isozymes. International journal of molecular sciences 24 (13) (2023)
Adriana Yamaguchi, Christopher van Hoorebeke, Benjamin E Tourdot, Steven C Perry, Grace Lee, Nicole M Rhoads, Andrew Rickenberg, Abigail R Green, James Sorrentino, Jennifer Yeung, J Cody Freedman, Theodore R Holman, Michael A Holinstat
Fatty acids negatively regulate platelet function through formation of noncanonical 15-lipoxygenase-derived eicosanoids. Pharmacology research & perspectives 11 (1) (2023)
Bryan Harris, Dinesh K Singh, Monika Verma, Shawn P Fahl, Michele Rhodes, Shanna R Sprinkle, Minshi Wang, Yong Zhang, Jaqueline Perrigoue, Rachel Kessel, Suraj Peri, Joshua West, Orsi Giricz, Jacqueline Boultwood, Andrea Pellagatti, K H Ramesh, Cristina Montagna, Kith Pradhan, Jeffrey W Tyner, Brian K Kennedy, Michael A Holinstat, Ulrich Steidl, Stephen Sykes, Amit Verma, David L Wiest
Ribosomal protein control of hematopoietic stem cell transformation through direct, non-canonical regulation of metabolism. bioRxiv : the preprint server for biology (2023)
Alison L Banka, M Valentina Guevara, Emma R Brannon, Nhien Q Nguyen, Shuang Song, Gillian Cady, David J Pinsky, Kathryn E Uhrich, Reheman Adili, Michael A Holinstat, Omolola Eniola-Adefeso
Cargo-free particles divert neutrophil-platelet aggregates to reduce thromboinflammation. Nature communications 14 (1) (2023)
Livia Stanger, Adriana Yamaguchi, Pooja Yalavarthi, Sylviane Lambert, Devin Gilmore, Andrew Rickenberg, Catherine Luke, Kiran Kumar, Andrea Tara Obi, Andrew White, Niklas Berg, Bjorn Lennart Dahlof, Michael A Holinstat
The oxylipin analogue CS585 prevents platelet activation and thrombosis through activation of the prostacyclin receptor. Blood (2023)
Sriganesh B Sharma, William James Melvin, Christopher O Audu, Monica Bame, Nicole M Rhoads, Weisheng Wu, Yogendra Kanthi, Christian Lood, Reheman Adili, Michael A Holinstat, Thomas W Wakefield, Peter K Henke, Bethany B Moore, Katherine Ann Gallagher, Andrea Tara Obi
The histone methyltransferase MLL1/KMT2A in monocytes drives coronavirus-associated coagulopathy and inflammation. Blood 141 (7) (2023)
Sriganesh B Sharma, William James Melvin, Christopher O Audu, Monica Bame, Nicole M Rhoads, Weisheng Wu, Yogendra Kanthi, Christian Lood, Reheman Adili, Michael A Holinstat, Thomas W Wakefield, Peter K Henke, Bethany B Moore, Katherine Ann Gallagher, Andrea Tara Obi
The histone methyltransferase MLL1/KMT2A in monocytes drives coronavirus-associated coagulopathy and inflammation. Blood 141 (7) (2023)
Chanel C La, Stephanie A Smith, Sreeparna Vappala, Reheman Adili, Catherine E Luke, Srinivas Abbina, Haiming D Luo, Irina Chafeeva, Matthew Drayton, Louise A Creagh, María de Guadalupe Jaraquemada-Peláez, Nicole M Rhoads, Manu Thomas Kalathottukaren, Peter K Henke, Suzana K Straus, Caigan Du, Edward M Conway, Michael A Holinstat, Charles A Haynes, James H Morrissey, Jayachandran N Kizhakkedathu
Smart thrombosis inhibitors without bleeding side effects via charge tunable ligand design. Nature communications 14 (1) (2023)
Alison L Banka, M Valentina Guevara, Emma R Brannon, Nhien Q Nguyen, Shuang Song, Gillian Cady, David J Pinsky, Kathryn E Uhrich, Reheman Adili, Michael A Holinstat, Omolola Eniola-Adefeso
Cargo-free particles divert neutrophil-platelet aggregates to reduce thromboinflammation. Nature communications 14 (1) (2023)
Chanel C La, Stephanie A Smith, Sreeparna Vappala, Reheman Adili, Catherine E Luke, Srinivas Abbina, Haiming D Luo, Irina Chafeeva, Matthew Drayton, Louise A Creagh, María de Guadalupe Jaraquemada-Peláez, Nicole M Rhoads, Manu Thomas Kalathottukaren, Peter K Henke, Suzana K Straus, Caigan Du, Edward M Conway, Michael A Holinstat, Charles A Haynes, James H Morrissey, Jayachandran N Kizhakkedathu
Smart thrombosis inhibitors without bleeding side effects via charge tunable ligand design. Nature communications 14 (1) (2023)
Alison L Banka, M Valentina Guevara, Emma R Brannon, Nhien Q Nguyen, Shuang Song, Gillian Cady, David J Pinsky, Kathryn E Uhrich, Reheman Adili, Michael A Holinstat, Omolola Eniola-Adefeso
Cargo-free particles divert neutrophil-platelet aggregates to reduce thromboinflammation. Nature communications 14 (1) (2023)
Chanel C La, Stephanie A Smith, Sreeparna Vappala, Reheman Adili, Catherine E Luke, Srinivas Abbina, Haiming D Luo, Irina Chafeeva, Matthew Drayton, Louise A Creagh, María de Guadalupe Jaraquemada-Peláez, Nicole M Rhoads, Manu Thomas Kalathottukaren, Peter K Henke, Suzana K Straus, Caigan Du, Edward M Conway, Michael A Holinstat, Charles A Haynes, James H Morrissey, Jayachandran N Kizhakkedathu
Smart thrombosis inhibitors without bleeding side effects via charge tunable ligand design. Nature communications 14 (1) (2023)
Adriana Yamaguchi, Livia Stanger, John Cody Freedman, Amanda Prieur, Rachel Thav, Jennyfer Tena, Theodore R Holman, Michael A Holinstat
Supplementation with omega-3 or omega-6 fatty acids attenuates platelet reactivity in postmenopausal women. Clinical and translational science 15 (10) (2022)
Sriganesh B Sharma, William James Melvin, Christopher O Audu, Monica Bame, Nicole M Rhoads, Weisheng Wu, Yogendra Kanthi, Christian Lood, Reheman Adili, Michael A Holinstat, Thomas W Wakefield, Peter Henke, Bethany B Moore, Katherine Ann Gallagher, Andrea Tara Obi
The Histone Methyltransferase MLL1/KMT2A in Monocytes Drives Coronavirus-Associated Coagulopathy and Inflammation. Blood (2022)
Sriganesh B Sharma, William James Melvin, Christopher O Audu, Monica Bame, Nicole M Rhoads, Weisheng Wu, Yogendra Kanthi, Christian Lood, Reheman Adili, Michael A Holinstat, Thomas W Wakefield, Peter Henke, Bethany B Moore, Katherine Ann Gallagher, Andrea Tara Obi
The Histone Methyltransferase MLL1/KMT2A in Monocytes Drives Coronavirus-Associated Coagulopathy and Inflammation. Blood (2022)
Sriganesh B Sharma, William James Melvin, Christopher O Audu, Monica Bame, Nicole M Rhoads, Weisheng Wu, Yogendra Kanthi, Christian Lood, Reheman Adili, Michael A Holinstat, Thomas W Wakefield, Peter Henke, Bethany B Moore, Katherine Ann Gallagher, Andrea Tara Obi
The Histone Methyltransferase MLL1/KMT2A in Monocytes Drives Coronavirus-Associated Coagulopathy and Inflammation. Blood (2022)
Sriganesh B Sharma, William James Melvin, Christopher O Audu, Monica Bame, Nicole M Rhoads, Weisheng Wu, Yogendra Kanthi, Christian Lood, Reheman Adili, Michael A Holinstat, Thomas W Wakefield, Peter Henke, Bethany B Moore, Katherine Ann Gallagher, Andrea Tara Obi
The Histone Methyltransferase MLL1/KMT2A in Monocytes Drives Coronavirus-Associated Coagulopathy and Inflammation. Blood (2022)
Sriganesh B Sharma, William James Melvin, Christopher O Audu, Monica Bame, Nicole M Rhoads, Weisheng Wu, Yogendra Kanthi, Christian Lood, Reheman Adili, Michael A Holinstat, Thomas W Wakefield, Peter Henke, Bethany B Moore, Katherine Ann Gallagher, Andrea Tara Obi
The Histone Methyltransferase MLL1/KMT2A in Monocytes Drives Coronavirus-Associated Coagulopathy and Inflammation. Blood (2022)
Michael A Holinstat
Trauma is an exhausting platelet experience. Journal of thrombosis and haemostasis : JTH 20 (9) (2022)
Elizabeth P Darga, Emily M Dolce, Fang Fang, Kelley M Kidwell, Christina L Gersch, Steven Kregel, Dafydd G Thomas, Anoop Gill, Martha E Brown, Steven Gross, Mark Connelly, Michael A Holinstat, Erin F Cobain, James M Rae, Daniel F Hayes, Costanza Paoletti
PD-L1 expression on circulating tumor cells and platelets in patients with metastatic breast cancer. PloS one 16 (11) (2021)
Reheman Adili, Madeline Jackson, Livia Stanger, Xiangrong Dai, Mandy Li, Benjamin Xiaoyi Li, Michael A Holinstat
Slounase, a Batroxobin Containing Activated Factor X Effectively Enhances Hemostatic Clot Formation and Reducing Bleeding in Hypocoagulant Conditions in Mice. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 27 (2021)
Margaret B Fish, Alison L Banka, Margaret Braunreuther, Catherine A Fromen, William J Kelley, Jonathan Lee, Reheman Adili, Michael A Holinstat, Omolola Eniola-Adefeso
Deformable microparticles for shuttling nanoparticles to the vascular wall. Science advances 7 (17) (2021)
Adriana Yamaguchi, Livia Stanger, Cody J Freedman, Melissa Standley, Timothy Hoang, Reheman Adili, Wan-Chen Tsai, Christopher van Hoorebeke, Theodore R Holman, Michael A Holinstat
DHA 12-LOX-derived oxylipins regulate platelet activation and thrombus formation through a PKA-dependent signaling pathway. Journal of thrombosis and haemostasis : JTH 19 (3) (2020)
Hongliang He, Reheman Adili, Lisha Liu, Kristen Hong, Michael A Holinstat, Anna A Schwendeman
Synthetic high-density lipoproteins loaded with an antiplatelet drug for efficient inhibition of thrombosis in mice. Science advances 6 (49) (2020)
Jennifer Yeung, Reheman Adili, Emily N Stringham, Rong Luo, Alexander Vizurraga, Luciana K Rosselli-Murai, Hannah M Stoveken, Maiya Yu, Xianhua Piao, Michael A Holinstat, Gregory G Tall
GPR56/ADGRG1 is a platelet collagen-responsive GPCR and hemostatic sensor of shear force. Proceedings of the National Academy of Sciences of the United States of America 117 (45) (2020)
Megan S Rost, Ilya Shestopalov, Yang Liu, Andy H Vo, Catherine E Richter, Sylvia M Emly, Francesca G Barrett, David L Stachura, Michael A Holinstat, Leonard I Zon, Jordan A Shavit
Nfe2 is dispensable for early but required for adult thrombocyte formation and function in zebrafish. Blood advances 2 (23) (2019)
Michael A Holinstat
Complement factors (H) into thrombosis. Blood 129 (9) (2018)
Jennifer Yeung, Megan Hawley, Michael A Holinstat
The expansive role of oxylipins on platelet biology. Journal of molecular medicine (Berlin, Germany) 95 (6) (2017)

Michael A Holinstat.css-eqlu8i{font-size:small;padding-left:4px;} (Michael Holinstat)

Publication Activity (10 Years)

Top Topics

Top Venues

Michael A Holinstat (Michael Holinstat)