Single-Cell Transcriptomics Reveals the Difference of Aortic Atherosclerosis Response to Phytosterols and Oxidation Products of Sterols.
Zhangtie WangMengmeng WangYunrui LuYongli JiBernabé Nuñez-EstevezFan XiaoYan LiuLiangxiao ZhangMaurizio BattinoPeiwu LiJianbo XiaoYao XieBaiyi LuPublished in: Molecular nutrition & food research (2023)
Our data elucidates the effects of dietary PS/COPs/POPs on aortic cells during atherosclerosis development, especially on the newly identified fibroblast subpopulations. This article is protected by copyright. All rights reserved.
Keyphrases
- single cell
- aortic valve
- induced apoptosis
- rna seq
- cardiovascular disease
- left ventricular
- pulmonary artery
- cell cycle arrest
- aortic dissection
- high throughput
- electronic health record
- hydrogen peroxide
- big data
- cell death
- type diabetes
- endoplasmic reticulum stress
- heart failure
- coronary artery
- oxidative stress
- signaling pathway
- nitric oxide
- pulmonary hypertension
- cell proliferation