Investigation of genetically regulated gene expression and response to treatment in rheumatoid arthritis highlights an association between IL18RAP expression and treatment response.

Svetlana CherlinMyles J LewisDarren PlantNisha NairKatriona GoldmannEvan TzanisMichael R BarnesPaul McKeigueJennifer H BarrettCostantino PitzalisAnne Bartonnull nullHeather J Cordell

Published in: Annals of the rheumatic diseases (2020)

Our results suggest that IL18RAP expression is worthy of further investigation as a potential predictor of treatment response in rheumatoid arthritis that is not specific to a particular drug type.

Keyphrases

rheumatoid arthritis
gene expression
poor prognosis
disease activity
dna methylation
binding protein
interstitial lung disease
transcription factor
emergency department
systemic lupus erythematosus
risk assessment
systemic sclerosis
adverse drug