Evaluating the effectiveness of simvastatin in slowing the progression of disability in secondary progressive multiple sclerosis (MS-STAT2): protocol for a multicentre, randomised controlled, double-blind, phase 3 clinical trial in the UK.
James BlackstoneThomas WilliamsJennifer M NicholasEkaterina BordeaFloriana De AngelisAlessia BianchiAlberto CalviAnisha DoshiNevin JohnSean Apap MangionCharles WadeRachel MerryGil BartonDawn LyleElisabeth JarmanDon MahadAbdullah ShehuTarunya ArunGavin McDonnellRuth GeraldesMatthew CranerCharles HillierJeban GanesalingamLeonora FisnikuJeremy HobartCord SpilkerNeil RobertsonSeema KalraStefano PluchinoSreedharan HarikrishnanMiriam MattoscioTimothy HarrowerCarolyn YoungMartin LeeSuresh ChhetriFayyaz AhmedDavid RogEli SilberPaul GallagherMartin DuddyAgne StraukieneRichard NicholasClaire RiceStuart J NixonJudy BeveridgeAnnie HawtonSusan TebbsMarie BraisherGavin GiovannoniOlga CiccarelliJohn GreenwoodAlan J ThompsonRachael Maree HunterSue PavittOwen PearsonNikos EvangelouBasil SharrackIan GaleaSiddharthan ChandranHelen L FordChris FrostJeremy ChatawayPublished in: BMJ open (2024)
NCT03387670; ISRCTN82598726.