Retrospective evaluation of routine whole genome sequencing of Mycobacterium tuberculosis at the Belgian National Reference Center, 2019.
Karine SoetaertPieter-Jan CeyssensSamira BoarbiBert BogaertsThomas DelcourtKevin VannesteSigrid C J De KeersmaeckerNancy H C RoosensAlexandra VodolazkaiaMarina MukovnikovaVanessa MathysPublished in: Acta clinica Belgica (2021)
Our study confirms the effectiveness of WGS for the rapid detection of M. tuberculosis complex and its drug resistance profiles for first-line drugs even when working directly on MGIT tubes, and supports the introduction of this test into the routine workflow of laboratories performing tuberculosis diagnosis.