Complete genome sequence of candidate probiotic Limosilactobacillus fermentum KUFM407.
Bogun KimJi Yu HeoXiaoyue XuHyunju LeeDuleepa PathirajaJae-Young KimYi Hyun ChoiIn-Geol ChoiSae-Hun KimPublished in: Journal of animal science and technology (2024)
It has been reported that the administration of Limosilactobacillus fermentum alleviates diseases such as osteoporosis and colitis. In this study, we report the complete genome sequence of Limosilactobacillus fermentum KUFM407, a probiotic strain of LAB isolated from Korean traditional fermented food, Kimchi. Whole genome sequencing of L. fermentum KUFM407 was performed on the Illumina MiSeq and Oxford Nanopore MinION platform. The genome consisted of one circular chromosome (2,077,616 base pair [bp]) with a guanine cytosine (GC) content of 51.5% and one circular plasmid sequence (13,931 bp). Genome annotation identified 1,932 protein-coding genes, 15 rRNAs, and 58 tRNAs in the assembly. The function annotation of the predicted proteins revealed genes involved in the biosynthesis of bacteriocin and fatty acids. The complete genome of L. fermentum KUFM407 could provide valuable information for the development of new probiotic food and health supplements.
Keyphrases
- genome wide
- lactic acid
- fatty acid
- bacillus subtilis
- healthcare
- public health
- escherichia coli
- mental health
- health information
- crispr cas
- high throughput
- single molecule
- copy number
- bone mineral density
- mouse model
- single cell
- protein protein
- high resolution
- small molecule
- social media
- ulcerative colitis
- solid state
- high throughput sequencing