Assessing the validity of plasma phospholipid fatty acids as biomarkers of dairy fat intake using data from a randomized controlled intervention trial.
Hilary J BethancourtKelsey A SchmidtGail CromerMaggie S BurhansJessica N KuzmaDerek K HagmanImashi FernandoMerideth MurrayKristina M UtzschneiderSarah E HolteRoss L PrenticeJana KraftMario KratzPublished in: The American journal of clinical nutrition (2022)
The potential for liver fat to affect relative plasma phospholipid concentrations of C15:0 and C17:0 raises questions about their validity as biomarkers of dairy fat intake. Of the fatty acid measures tested, trans-C16:1n-7 combined with iso-C17:0, especially with adjustment of liver fat, age, and sex, may provide the most robust estimate of dairy fat consumption.