Therapeutic Effects of Amaranth: Analysis of the Antidiabetic Potential of the Plant.
Andrea Campos HerreraFrancisco Valenzuela ZamudioMaira Rubi Segura CamposPublished in: Journal of medicinal food (2024)
Amaranth is a pseudocereal rich in macronutrients and micronutrients, with about 60 species cultivated worldwide. It is a high nutritional value food because of its many essential amino acids. Recent investigations demonstrate that the phytochemicals and extracts of amaranth have beneficial effects on health, including antidiabetic potential, a decrease in plasmatic cholesterol and blood pressure, and protection from oxidative stress and inflammation. Nowadays, type 2 diabetes has increased worldwide, becoming a problem of public health that makes it necessary to look for alternative strategies for its prevention and treatment. This review aims to summarize the antidiabetic potential of diverse species of the Amaranth genus. A bibliographical review was updated on the plant's therapeutic potential, including stem, leaves, and seeds, to know the benefits and potential as an adjuvant in treating and managing diabetes and associated pathologies (hypertension, dyslipidemia, and heart disease). This analysis contributes to the generation of knowledge about the therapeutic effects of amaranth, promoting the creation of new products, and the opportunity to conduct clinical trials to assess their safety and efficacy.
Keyphrases
- public health
- type diabetes
- blood pressure
- oxidative stress
- human health
- clinical trial
- cardiovascular disease
- early stage
- amino acid
- glycemic control
- risk assessment
- randomized controlled trial
- dna damage
- signaling pathway
- adipose tissue
- ischemia reperfusion injury
- social media
- open label
- induced apoptosis
- heat stress
- smoking cessation
- global health
- phase iii