Eicosapentaenoic and Docosahexaenoic Acids Differentially Alter Gut Microbiome and Reverse High-Fat Diet-Induced Insulin Resistance.

Pan ZhuangYu ZhangQiyang ShouHaoyu LiYa'er ZhuLilin HeJingnan ChenJingjing Jiao

Published in: Molecular nutrition & food research (2020)

EPA and DHA differentially reverse IR and relieve adipose inflammation while modulating gut microbiome and SCFAs/LPS production, underscoring the gut-adipose axis as a primary target of EPA/DHA.

Keyphrases

insulin resistance
high fat diet induced
fatty acid
adipose tissue
metabolic syndrome
high fat diet
skeletal muscle
polycystic ovary syndrome
type diabetes
oxidative stress
inflammatory response
anti inflammatory
glycemic control