FUME-TCRseq Enables Sensitive and Accurate Sequencing of the T-cell Receptor from Limited Input of Degraded RNA.
Ann-Marie C BakerGayathri NageswaranPablo NenclaresTahel RonelKane SmithChristopher KimberleyMiangela M LacléShreerang A BhideKevin J HarringtonAlan A MelcherManuel RodriguezBenjamin M ChainTrevor A GrahamPublished in: Cancer research (2024)
FUME-TCRseq is a TCR sequencing methodology that supports sensitive and spatially resolved detection of TCR clones in archival clinical specimens, which can facilitate longitudinal tracking of immune responses through disease course and treatment.