Alan A Melcher (Alan Melcher, A A Melcher)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 29

Top Topics

Immune Response

Hematopoietic Stem Cell

Top Venues

Nature communications

Journal for immunotherapy of cancer

Cancer research

This page only lists publications with an associated author ORCID identifier.

Publications

Emmanuel C Patin, Pablo Nenclares, Charleen Chan Wah Hak, Magnus T Dillon, Anton Patrikeev, Martin McLaughlin, Lorna Grove, Shane Foo, Heba Soliman, Joao P Barata, Joanna Marsden, Holly Baldock, Jim Gkantalis, Victoria Roulstone, Joan Kyula, Amy Burley, Lisa Hubbard, Malin Pedersen, Simon A Smith, Eleanor Clancy-Thompson, Alan A Melcher, Masahiro Ono, Antonio José Rullán, Kevin J Harrington
Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent adjuvant immunotherapy. Nature communications 15 (1) (2024)
Mason James Webb, Thanich Sangsuwannukul, Jacob van Vloten, Laura Evgin, Benjamin Kendall, Jason Tonne, Jill Thompson, Muriel Metko, Madelyn Moore, Maria P Chiriboga Yerovi, Michael Olin, Antonella Borgatti, Mark McNiven, Satdarshan Paul Monga, Mitesh J Borad, Alan A Melcher, Lewis Rowland Roberts, Richard G Vile
Expression of tumor antigens within an oncolytic virus enhances the anti-tumor T cell response. Nature communications 15 (1) (2024)
Edward Armstrong, Matthew K L Chiu, Shane Foo, Lizzie Appleton, Pablo Nenclares, Anton Patrikeev, Nitya Mohan, Martin Mclaughlin, Galabina Bozhanova, Julia Hoebart, Victoria Roulstone, Emmanuel C Patin, Malin Pedersen, Joan Kyula, Masahiro Ono, Fiona Errington-Mais, John Cameron Bell, Kevin J Harrington, Alan A Melcher, Victoria Jennings
Combination of oncolytic Maraba virus with immune checkpoint blockade overcomes therapy resistance in an immunologically cold model of advanced melanoma with dysfunctional T-cell receptor signalling. Journal for immunotherapy of cancer 12 (7) (2024)
Mason James Webb, Thanich Sangsuwannukul, Jacob van Vloten, Laura Evgin, Benjamin Kendall, Jason Tonne, Jill Thompson, Muriel Metko, Madelyn Moore, Maria P Chiriboga Yerovi, Michael Olin, Antonella Borgatti, Mark McNiven, Satdarshan Paul Monga, Mitesh J Borad, Alan A Melcher, Lewis Rowland Roberts, Richard G Vile
Expression of tumor antigens within an oncolytic virus enhances the anti-tumor T cell response. Nature communications 15 (1) (2024)
Edward Armstrong, Matthew K L Chiu, Shane Foo, Lizzie Appleton, Pablo Nenclares, Anton Patrikeev, Nitya Mohan, Martin Mclaughlin, Galabina Bozhanova, Julia Hoebart, Victoria Roulstone, Emmanuel C Patin, Malin Pedersen, Joan Kyula, Masahiro Ono, Fiona Errington-Mais, John Cameron Bell, Kevin J Harrington, Alan A Melcher, Victoria Jennings
Combination of oncolytic Maraba virus with immune checkpoint blockade overcomes therapy resistance in an immunologically cold model of advanced melanoma with dysfunctional T-cell receptor signalling. Journal for immunotherapy of cancer 12 (7) (2024)
Edward Armstrong, Matthew K L Chiu, Shane Foo, Lizzie Appleton, Pablo Nenclares, Anton Patrikeev, Nitya Mohan, Martin Mclaughlin, Galabina Bozhanova, Julia Hoebart, Victoria Roulstone, Emmanuel C Patin, Malin Pedersen, Joan Kyula, Masahiro Ono, Fiona Errington-Mais, John Cameron Bell, Kevin J Harrington, Alan A Melcher, Victoria Jennings
Combination of oncolytic Maraba virus with immune checkpoint blockade overcomes therapy resistance in an immunologically cold model of advanced melanoma with dysfunctional T-cell receptor signalling. Journal for immunotherapy of cancer 12 (7) (2024)
Ann-Marie C Baker, Gayathri Nageswaran, Pablo Nenclares, Tahel Ronel, Kane Smith, Christopher Kimberley, Miangela M Laclé, Shreerang A Bhide, Kevin J Harrington, Alan A Melcher, Manuel Rodriguez, Benjamin M Chain, Trevor A Graham
FUME-TCRseq Enables Sensitive and Accurate Sequencing of the T-cell Receptor from Limited Input of Degraded RNA. Cancer research 84 (10) (2024)
Mason James Webb, Thanich Sangsuwannukul, Jacob van Vloten, Laura Evgin, Benjamin Kendall, Jason Tonne, Jill Thompson, Muriel Metko, Madelyn Moore, Maria P Chiriboga Yerovi, Michael Olin, Antonella Borgatti, Mark McNiven, Satdarshan Paul Monga, Mitesh J Borad, Alan A Melcher, Lewis Rowland Roberts, Richard G Vile
Expression of tumor antigens within an oncolytic virus enhances the anti-tumor T cell response. Nature communications 15 (1) (2024)
Emmanuel C Patin, Pablo Nenclares, Charleen Chan Wah Hak, Magnus T Dillon, Anton Patrikeev, Martin McLaughlin, Lorna Grove, Shane Foo, Heba Soliman, Joao P Barata, Joanna Marsden, Holly Baldock, Jim Gkantalis, Victoria Roulstone, Joan Kyula, Amy Burley, Lisa Hubbard, Malin Pedersen, Simon A Smith, Eleanor Clancy-Thompson, Alan A Melcher, Masahiro Ono, Antonio José Rullán, Kevin J Harrington
Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent adjuvant immunotherapy. Nature communications 15 (1) (2024)
Emmanuel C Patin, Pablo Nenclares, Charleen Chan Wah Hak, Magnus T Dillon, Anton Patrikeev, Martin McLaughlin, Lorna Grove, Shane Foo, Heba Soliman, Joao P Barata, Joanna Marsden, Holly Baldock, Jim Gkantalis, Victoria Roulstone, Joan Kyula, Amy Burley, Lisa Hubbard, Malin Pedersen, Simon A Smith, Eleanor Clancy-Thompson, Alan A Melcher, Masahiro Ono, Antonio José Rullán, Kevin J Harrington
Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent adjuvant immunotherapy. Nature communications 15 (1) (2024)
Edward Armstrong, Matthew K L Chiu, Shane Foo, Lizzie Appleton, Pablo Nenclares, Anton Patrikeev, Nitya Mohan, Martin Mclaughlin, Galabina Bozhanova, Julia Hoebart, Victoria Roulstone, Emmanuel C Patin, Malin Pedersen, Joan Kyula, Masahiro Ono, Fiona Errington-Mais, John Cameron Bell, Kevin J Harrington, Alan A Melcher, Victoria Jennings
Combination of oncolytic Maraba virus with immune checkpoint blockade overcomes therapy resistance in an immunologically cold model of advanced melanoma with dysfunctional T-cell receptor signalling. Journal for immunotherapy of cancer 12 (7) (2024)
Edward Armstrong, Matthew K L Chiu, Shane Foo, Lizzie Appleton, Pablo Nenclares, Anton Patrikeev, Nitya Mohan, Martin Mclaughlin, Galabina Bozhanova, Julia Hoebart, Victoria Roulstone, Emmanuel C Patin, Malin Pedersen, Joan Kyula, Masahiro Ono, Fiona Errington-Mais, John Cameron Bell, Kevin J Harrington, Alan A Melcher, Victoria Jennings
Combination of oncolytic Maraba virus with immune checkpoint blockade overcomes therapy resistance in an immunologically cold model of advanced melanoma with dysfunctional T-cell receptor signalling. Journal for immunotherapy of cancer 12 (7) (2024)
Emmanuel C Patin, Pablo Nenclares, Charleen Chan Wah Hak, Magnus T Dillon, Anton Patrikeev, Martin McLaughlin, Lorna Grove, Shane Foo, Heba Soliman, Joao P Barata, Joanna Marsden, Holly Baldock, Jim Gkantalis, Victoria Roulstone, Joan Kyula, Amy Burley, Lisa Hubbard, Malin Pedersen, Simon A Smith, Eleanor Clancy-Thompson, Alan A Melcher, Masahiro Ono, Antonio José Rullán, Kevin J Harrington
Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent adjuvant immunotherapy. Nature communications 15 (1) (2024)
Mason James Webb, Thanich Sangsuwannukul, Jacob van Vloten, Laura Evgin, Benjamin Kendall, Jason Tonne, Jill Thompson, Muriel Metko, Madelyn Moore, Maria P Chiriboga Yerovi, Michael Olin, Antonella Borgatti, Mark McNiven, Satdarshan Paul Monga, Mitesh J Borad, Alan A Melcher, Lewis Rowland Roberts, Richard G Vile
Expression of tumor antigens within an oncolytic virus enhances the anti-tumor T cell response. Nature communications 15 (1) (2024)
Emmanuel C Patin, Pablo Nenclares, Charleen Chan Wah Hak, Magnus T Dillon, Anton Patrikeev, Martin McLaughlin, Lorna Grove, Shane Foo, Heba Soliman, Joao P Barata, Joanna Marsden, Holly Baldock, Jim Gkantalis, Victoria Roulstone, Joan Kyula, Amy Burley, Lisa Hubbard, Malin Pedersen, Simon A Smith, Eleanor Clancy-Thompson, Alan A Melcher, Masahiro Ono, Antonio José Rullán, Kevin J Harrington
Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent adjuvant immunotherapy. Nature communications 15 (1) (2024)
Ann-Marie C Baker, Gayathri Nageswaran, Pablo Nenclares, Tahel Ronel, Kane Smith, Christopher Kimberley, Miangela M Laclé, Shreerang A Bhide, Kevin J Harrington, Alan A Melcher, Manuel Rodriguez, Benjamin M Chain, Trevor A Graham
FUME-TCRseq Enables Sensitive and Accurate Sequencing of the T-cell Receptor from Limited Input of Degraded RNA. Cancer research 84 (10) (2024)
Ann-Marie C Baker, Gayathri Nageswaran, Pablo Nenclares, Tahel Ronel, Kane Smith, Christopher Kimberley, Miangela M Laclé, Shreerang A Bhide, Kevin J Harrington, Alan A Melcher, Manuel Rodriguez, Benjamin M Chain, Trevor A Graham
FUME-TCRseq enables sensitive and accurate sequencing of the T-cell receptor from limited input of degraded RNA. Cancer research (2024)
Ann-Marie C Baker, Gayathri Nageswaran, Pablo Nenclares, Tahel Ronel, Kane Smith, Christopher Kimberley, Miangela M Laclé, Shreerang A Bhide, Kevin J Harrington, Alan A Melcher, Manuel Rodriguez, Benjamin M Chain, Trevor A Graham
FUME-TCRseq Enables Sensitive and Accurate Sequencing of the T-cell Receptor from Limited Input of Degraded RNA. Cancer research 84 (10) (2024)
Fabiana Gregucci, Sheila Spada, Mary Helen Barcellos-Hoff, Nina Bhardwaj, Charleen Chan Wah Hak, Alba Fiorentino, Chandan Guha, Monica L Guzman, Kevin J Harrington, Fernanda G Herrera, Jamie Honeychurch, Theodore S Hong, Lorea Iturri, Elisabeth Jaffee, Sana D Karam, Simon R V Knott, Constantinos Koumenis, David C Lyden, Ariel E Marciscano, Alan A Melcher, Michele Mondini, Anna Mondino, Zachary S Morris, Sean P Pitroda, Sergio A Quezada, Laura Santambrogio, Stephen L Shiao, John Stagg, Irma Telarovic, Robert Timmerman, Marie-Catherine Vozenin, Ralph R Weichselbaum, James Welsh, Anna C Wilkins, Chris Xu, Roberta Zappasodi, Weiping Zou, Alexandre Bobard, Sandra Demaria, Lorenzo Galluzzi, Eric Deutsch, Sylvia C Formenti
Updates on radiotherapy-immunotherapy combinations: Proceedings of 6 th annual ImmunoRad conference. Oncoimmunology 12 (1) (2023)
Fabiana Gregucci, Sheila Spada, Mary Helen Barcellos-Hoff, Nina Bhardwaj, Charleen Chan Wah Hak, Alba Fiorentino, Chandan Guha, Monica L Guzman, Kevin J Harrington, Fernanda G Herrera, Jamie Honeychurch, Theodore S Hong, Lorea Iturri, Elisabeth Jaffee, Sana D Karam, Simon R V Knott, Constantinos Koumenis, David C Lyden, Ariel E Marciscano, Alan A Melcher, Michele Mondini, Anna Mondino, Zachary S Morris, Sean P Pitroda, Sergio A Quezada, Laura Santambrogio, Stephen L Shiao, John Stagg, Irma Telarovic, Robert Timmerman, Marie-Catherine Vozenin, Ralph R Weichselbaum, James Welsh, Anna C Wilkins, Chris Xu, Roberta Zappasodi, Weiping Zou, Alexandre Bobard, Sandra Demaria, Lorenzo Galluzzi, Eric Deutsch, Sylvia C Formenti
Updates on radiotherapy-immunotherapy combinations: Proceedings of 6 th annual ImmunoRad conference. Oncoimmunology 12 (1) (2023)
Fabiana Gregucci, Sheila Spada, Mary Helen Barcellos-Hoff, Nina Bhardwaj, Charleen Chan Wah Hak, Alba Fiorentino, Chandan Guha, Monica L Guzman, Kevin J Harrington, Fernanda G Herrera, Jamie Honeychurch, Theodore S Hong, Lorea Iturri, Elisabeth Jaffee, Sana D Karam, Simon R V Knott, Constantinos Koumenis, David C Lyden, Ariel E Marciscano, Alan A Melcher, Michele Mondini, Anna Mondino, Zachary S Morris, Sean P Pitroda, Sergio A Quezada, Laura Santambrogio, Stephen L Shiao, John Stagg, Irma Telarovic, Robert Timmerman, Marie-Catherine Vozenin, Ralph R Weichselbaum, James Welsh, Anna C Wilkins, Chris Xu, Roberta Zappasodi, Weiping Zou, Alexandre Bobard, Sandra Demaria, Lorenzo Galluzzi, Eric Deutsch, Sylvia C Formenti
Updates on radiotherapy-immunotherapy combinations: Proceedings of 6 th annual ImmunoRad conference. Oncoimmunology 12 (1) (2023)
Patrycja Gazinska, Charlotte K Milton, Jacopo Iacovacci, Joseph A Ward, Richard Buus, Thanussuyah Alaguthurai, Rosalind Graham, Ayse U Akarca, Esther H Lips, Kalnisha Naidoo, Jelle Wesseling, Teresa Marafioti, Maggie Chon U Cheang, Cheryl Gillett, Yin Wu, Aadil A Khan, Alan A Melcher, Roberto Salgado, Mitchell Dowsett, Andrew N J Tutt, Ioannis Roxanis, Syed Haider, Sheeba Irshad
Dynamic Changes in the NK-, Neutrophil-, and B-cell Immunophenotypes Relevant in High Metastatic Risk Post Neoadjuvant Chemotherapy-Resistant Early Breast Cancers. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (20) (2022)
Matthew R Schuelke, Justin H Gundelach, Matt Coffey, Emma West, Karen Scott, Derek R Johnson, Adel Samson, Alan A Melcher, Richard G Vile, Richard J Bram
Phase I trial of sargramostim/pelareorep therapy in pediatric patients with recurrent or refractory high-grade brain tumors. Neuro-oncology advances 4 (1) (2022)
Galabina Bozhanova, Jehanne Hassan, Lizzie Appleton, Victoria Jennings, Shane Foo, Martin McLaughlin, Charleen Ml Chan Wah Hak, Emmanuel C Patin, Eva Crespo-Rodriguez, Gabby Baker, Edward Armstrong, Matthew Chiu, Hardev Pandha, Adel Samson, Victoria Roulstone, Joan Kyula, Richard Vile, Fiona Errington-Mais, Malin Pedersen, Kevin J Harrington, Masahiro Ono, Alan A Melcher
CD4 T cell dynamics shape the immune response to combination oncolytic herpes virus and BRAF inhibitor therapy for melanoma. Journal for immunotherapy of cancer 10 (3) (2022)
Laura Evgin, Tim Kottke, Jason Tonne, Jill Thompson, Amanda L Huff, Jacob P van Vloten, Madelyn Moore, Josefine Michael, Christopher B Driscoll, Jose Pulido, Eric Swanson, Richard B Kennedy, Matthew Coffey, Houra Loghmani, Luis Sanchez-Perez, Gloria R Olivier, Kevin J Harrington, Hardev Pandha, Alan A Melcher, Rosa Maria Diaz, Richard G Vile
Oncolytic virus-mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice. Science translational medicine 14 (640) (2022)
Tereza Andreou, Jennifer Williams, Rebecca J Brownlie, Robert J Salmond, Erica B Wilson, Gary C Shaw, Alan A Melcher, Heiko Wurdak, Susan C Short, Mihaela Lorger
Hematopoietic stem cell gene therapy targeting TGFβ enhances the efficacy of irradiation therapy in a preclinical glioblastoma model. Journal for immunotherapy of cancer 9 (3) (2021)
H J Close, Lucy F Stead, J Nsengimana, K A Reilly, Alastair P Droop, Heiko Wurdak, Ryan Koshy Mathew, R Corns, J Newton-Bishop, Alan A Melcher, Susan C Short, Graham P Cook, Erica B Wilson
Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma. Clinical and experimental immunology 200 (1) (2019)
Adel Samson, Karen J Scott, David Taggart, Emma J West, Erica B Wilson, Gerard J Nuovo, Simon Thomson, Robert Corns, Ryan Koshy Mathew, Martin J Fuller, Timothy J Kottke, Jill M Thompson, Elizabeth J Ilett, Julia V Cockle, Philip van Hille, Gnanamurthy Sivakumar, Euan S Polson, Samantha J Turnbull, Elizabeth S Appleton, Gemma Migneco, Ailsa S Rose, Matthew C Coffey, Deborah A Beirne, Fiona J Collinson, Christy Ralph, Alan Anthony, Christopher J Twelves, Andrew J Furness, Sergio A Quezada, Heiko Wurdak, Fiona Errington-Mais, Hardev Pandha, Kevin J Harrington, Peter John Selby, Richard G Vile, Stephen D Griffin, Lucy F Stead, Susan C Short, Alan A Melcher
Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade. Science translational medicine 10 (422) (2019)
Aadil A Khan, James T E Paget, Martin McLaughlin, Joan N Kyula, Michelle J Wilkinson, Timothy Pencavel, David Mansfield, Victoria Roulstone, Rohit Seth, Martin Halle, Navita Somaiah, Jessica K R Boult, Simon P Robinson, Hardev S Pandha, Richard G Vile, Alan A Melcher, Paul A Harris, Kevin J Harrington
Genetically modified lentiviruses that preserve microvascular function protect against late radiation damage in normal tissues. Science translational medicine 10 (425) (2019)