[Diagnosis and Management of Esophageal and Gastric Variceal Bleeding: Focused on 2019 KASL Clinical Practice Guidelines for Liver Cirrhosis].
Min Kyung ParkYun Bin LeePublished in: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi (2021)
Varices are a frequent complication of liver cirrhosis and a major cause of mortality in patients with liver cirrhosis. Patients with decompensated cirrhosis complications have a poor prognosis and require careful management. Portal hypertension is the most common complication of liver cirrhosis, which is the key determinant for varices development. Increased intrahepatic vascular resistance to portal flow leads to the development of portal hypertension. Collateral vessels develop at the communication site between the systemic and portal circulation with the progression of portal hypertension. Varices are the representative collaterals, develop gradually with the progression of portal hypertension and may eventually rupture. Variceal bleeding is a major consequence of portal hypertension and causes the death of cirrhotic patients. The present paper reviews the latest knowledge regarding the diagnosis and management of esophageal and gastric variceal bleeding.
Keyphrases
- blood pressure
- poor prognosis
- atrial fibrillation
- end stage renal disease
- heart failure
- ejection fraction
- long non coding rna
- chronic kidney disease
- healthcare
- randomized controlled trial
- newly diagnosed
- type diabetes
- systematic review
- peritoneal dialysis
- prognostic factors
- cardiovascular events
- arterial hypertension
- cross sectional
- meta analyses