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Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern.

Hyeseon ChoKristina Kay Gonzales-WartzDeli HuangMeng YuanMary E PetersonJanie LiangNathan BeutlerJonathan L TorreYu CongElena PostnikovaSandhya BangaruChloe Adrienna TalanaWei ShiEun Sung YangYi ZhangKwanyee LeungLingshu WangLinghang PengJeff SkinnerShanping LiNicholas C WuHejun LiuCherrelle DaconThomas MoyerMelanie CohenMing ZhaoFrances Eun-Hyung LeeRona Singer WeinbergIyadh DouagiRobin GrossConnie S SchmaljohnAmarendra PeguJohn R MascolaMichael R HolbrookDavid NemazeeThomas F RogersAndrew B WardIan A WilsonPeter Dobbs CromptonJoshua Tan
Published in: Science translational medicine (2021)
[Figure: see text].
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • copy number
  • cancer therapy
  • smoking cessation
  • protein protein
  • amino acid
  • binding protein
  • gene expression
  • small molecule
  • coronavirus disease
  • drug delivery
  • genome wide