David Nemazee

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 30

Top Topics

Top Venues

Science (New York, N.Y.)

Nature communications

bioRxiv : the preprint server for biology

Science translational medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Amanda L Gavin, Tanya R Blane, Therese C Thinnes, Emma Gerlt, Ann Marshak-Rothstein, Deli Huang, David Nemazee
Disease in the Pld4thss/thss Model of Murine Lupus Requires TLR9. ImmunoHorizons 7 (8) (2023)
Meng Yuan, Linghang Peng, Deli Huang, Amanda Gavin, Fangkun Luan, Jenny Tran, Ziqi Feng, Xueyong Zhu, Jeanne Matteson, Ian A Wilson, David Nemazee
Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4. bioRxiv : the preprint server for biology (2023)
Fangzhu Zhao, Meng Yuan, Celina Keating, Namir Shaabani, Oliver Limbo, Collin Joyce, Jordan L Woehl, Shawn Barman, Alison Burns, Quoc Tran, Xueyong Zhu, Michael J Ricciardi, Linghang Peng, Jessica Smith, Deli Huang, Bryan Briney, Devin Sok, David Nemazee, John R Teijaro, Ian A Wilson, Dennis R Burton, Joseph G Jardine
Broadening a SARS-CoV-1-neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution. Science signaling 16 (798) (2023)
Cherrelle Dacon, Courtney Tucker, Linghang Peng, Chang-Chun David Lee, Ting-Hui Lin, Meng Yuan, Yu Cong, Lingshu Wang, Lauren Purser, Jazmean K Williams, Chul-Woo Pyo, Ivan Košík, Zhe Hu, Ming Zhao, Divya Mohan, Andrew J R Cooper, Mary E Peterson, Jeff Skinner, Saurabh Dixit, Erin Kollins, Louis Huzella, Donna Perry, Russell Byrum, Sanae Lembirik, David Drawbaugh, Brett Eaton, Yi Zhang, Eun Sung Yang, Man Chen, Kwanyee Leung, Rona Singer Weinberg, Amarendra Pegu, Daniel E Geraghty, Edgar Davidson, Iyadh Douagi, Susan L Moir, Jonathan W Yewdell, Connie S Schmaljohn, Peter Dobbs Crompton, Michael R Holbrook, David Nemazee, John R Mascola, Ian A Wilson, Joshua Tan
Broadly neutralizing antibodies target the coronavirus fusion peptide. Science (New York, N.Y.) 377 (6607) (2022)
Alessio David Nahmad, Cicera R Lazzarotto, Natalie Zelikson, Talia Kustin, Mary Tenuta, Deli Huang, Inbal Reuveni, Daniel Nataf, Yuval Raviv, Miriam Horovitz-Fried, Iris Dotan, Yaron Carmi, Rina Rosin-Arbesfeld, David Nemazee, James E Voss, Adi Stern, Shengdar Q Tsai, Adi Barzel
In vivo engineered B cells secrete high titers of broadly neutralizing anti-HIV antibodies in mice. Nature biotechnology 40 (8) (2022)
Wan-Ting He, Meng Yuan, Sean Callaghan, Rami Musharrafieh, Sophie Ge Song, Murillo Silva, Nathan Beutler, Wen-Hsin Lee, Peter Yong, Jonathan L Torre, Mariane B Melo, Panpan Zhou, Fangzhu Zhao, Xueyong Zhu, Linghang Peng, Deli Huang, Fabio Anzanello, James Ricketts, Mara Parren, Elijah Garcia, Melissa Ferguson, William Rinaldi, Stephen A Rawlings, David Nemazee, Davey M Smith, Bryan Briney, Yana Safonova, Thomas F Rogers, Jennifer M Dan, Zeli Zhang, Daniela Weiskopf, Alessandro Sette, Shane Crotty, Darrell J Irvine, Andrew B Ward, Ian A Wilson, Dennis R Burton, Raiees Andrabi
Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques. Science translational medicine 14 (657) (2022)
Panpan Zhou, Ge Song, Wan-Ting He, Nathan Beutler, Longping V Tse, David R Martinez, Alexandra Schäfer, Fabio Anzanello, Peter Yong, Linghang Peng, Katharina Dueker, Rami Musharrafieh, Sean Callaghan, Tazio Capozzola, Meng Yuan, Hejun Liu, Oliver Limbo, Mara Parren, Elijah Garcia, Stephen A Rawlings, Davey M Smith, David Nemazee, Joseph G Jardine, Ian A Wilson, Yana Safonova, Thomas F Rogers, Ralph S Baric, Lisa E Gralinski, Dennis R Burton, Raiees Andrabi
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe disease. bioRxiv : the preprint server for biology (2022)
Michael K Okoreeh, Domenick E Kennedy, Akinola Olumide Emmanuel, Margaret Veselits, Azam Moshin, Robert H Ladd, Steven A Erickson, Kaitlin C McLean, Brianna Madrigal, David Nemazee, Mark G Maienschein-Cline, Malay Mandal, Marcus R Clark
Asymmetrical forward and reverse developmental trajectories determine molecular programs of B cell antigen receptor editing. Science immunology 7 (74) (2022)
Panpan Zhou, Meng Yuan, Sophie Ge Song, Nathan Beutler, Namir Shaabani, Deli Huang, Wan-Ting He, Xueyong Zhu, Sean Callaghan, Peter Yong, Fabio Anzanello, Linghang Peng, James Ricketts, Mara Parren, Elijah Garcia, Stephen A Rawlings, Davey M Smith, David Nemazee, John R Teijaro, Thomas F Rogers, Ian A Wilson, Dennis R Burton, Raiees Andrabi
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection. Science translational medicine 14 (637) (2022)
Meng Yuan, Xueyong Zhu, Wan-Ting He, Panpan Zhou, Chengzi I Kaku, Tazio Capozzola, Connie Y Zhu, Xinye Yu, Hejun Liu, Wenli Yu, Yuanzi Hua, Henry Tien, Linghang Peng, Ge Song, Christopher A Cottrell, William R Schief, David Nemazee, Laura M Walker, Raiees Andrabi, Dennis R Burton, Ian A Wilson
A broad and potent neutralization epitope in SARS-related coronaviruses. Proceedings of the National Academy of Sciences of the United States of America 119 (29) (2022)
Hyeseon Cho, Kristina Kay Gonzales-Wartz, Deli Huang, Meng Yuan, Mary Peterson, Janie Liang, Nathan Beutler, Jonathan L Torres, Yu Cong, Elena Postnikova, Sandhya Bangaru, Chloe Adrienna Talana, Wei Shi, Eun Sung Yang, Yi Zhang, Kwanyee Leung, Lingshu Wang, Linghang Peng, Jeff Skinner, Shanping Li, Nicholas C Wu, Hejun Liu, Cherrelle Dacon, Thomas Moyer, Melanie Cohen, Ming Zhao, F Eun-Hyung Lee, Rona S Weinberg, Iyadh Douagi, Robin Gross, Connie Schmaljohn, Amarendra Pegu, John R Mascola, Michael R Holbrook, David Nemazee, Thomas F Rogers, Andrew B Ward, Ian A Wilson, Peter D Crompton, Joshua Tan
Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants. bioRxiv : the preprint server for biology (2021)
Meng Yuan, Deli Huang, Chang-Chun David Lee, Nicholas C Wu, Abigail M Jackson, Xueyong Zhu, Hejun Liu, Linghang Peng, Marit J VAN Gils, Rogier W Sanders, Dennis R Burton, S Momsen Reincke, Harald Prüss, Jakob Kreye, David Nemazee, Andrew B Ward, Ian A Wilson
Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants. Science (New York, N.Y.) 373 (6556) (2021)
Ge Song, Wan-Ting He, Sean Callaghan, Fabio Anzanello, Deli Huang, James Ricketts, Jonathan L Torre, Nathan Beutler, Linghang Peng, Sirena Vargas, Jon Cassell, Mara Parren, Linlin Yang, Caroline Ignacio, Davey M Smith, James E Voss, David Nemazee, Andrew B Ward, Thomas Rogers, Dennis R Burton, Raiees Andrabi
Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection. Nature communications 12 (1) (2021)
Deli Huang, Jenny Tuyet Tran, Linghang Peng, Linlin Yang, Raymond T Suhandynata, Melissa A Hoffman, Fangzhu Zhao, Sophie Ge Song, Wan-Ting He, Oliver Limbo, Sean Callaghan, Elise Landais, Raiees Andrabi, Devin Sok, Joseph G Jardine, Dennis R Burton, James E Voss, Robert L Fitzgerald, David Nemazee
A Rapid Assay for SARS-CoV-2 Neutralizing Antibodies That Is Insensitive to Antiretroviral Drugs. Journal of immunology (Baltimore, Md. : 1950) (2021)
Amanda L Gavin, Deli Huang, Tanya R Blane, Therese C Thinnes, Yusuke Murakami, Ryutaro Fukui, Kensuke Miyake, David Nemazee
Cleavage of DNA and RNA by PLD3 and PLD4 limits autoinflammatory triggering by multiple sensors. Nature communications 12 (1) (2021)
Hyeseon Cho, Kristina Kay Gonzales-Wartz, Deli Huang, Meng Yuan, Mary E Peterson, Janie Liang, Nathan Beutler, Jonathan L Torre, Yu Cong, Elena Postnikova, Sandhya Bangaru, Chloe Adrienna Talana, Wei Shi, Eun Sung Yang, Yi Zhang, Kwanyee Leung, Lingshu Wang, Linghang Peng, Jeff Skinner, Shanping Li, Nicholas C Wu, Hejun Liu, Cherrelle Dacon, Thomas Moyer, Melanie Cohen, Ming Zhao, Frances Eun-Hyung Lee, Rona Singer Weinberg, Iyadh Douagi, Robin Gross, Connie S Schmaljohn, Amarendra Pegu, John R Mascola, Michael R Holbrook, David Nemazee, Thomas F Rogers, Andrew B Ward, Ian A Wilson, Peter Dobbs Crompton, Joshua Tan
Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern. Science translational medicine 13 (616) (2021)
C Garrett Rappazzo, Longping V Tse, Chengzi I Kaku, Daniel Wrapp, Mrunal Sakharkar, Deli Huang, Laura M Deveau, Thomas J Yockachonis, Andrew S Herbert, Michael B Battles, Cecilia M O'Brien, Michael E Brown, James C Geoghegan, Jonathan Belk, Linghang Peng, Linlin Yang, Yixuan J Hou, Trevor D Scobey, Dennis R Burton, David Nemazee, John M Dye, James E Voss, Bronwyn M Gunn, Jason S Mclellan, Ralph S Baric, Lisa E Gralinski, Laura M Walker
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody. Science (New York, N.Y.) 371 (6531) (2021)
Thomas F Rogers, Fangzhu Zhao, Deli Huang, Nathan Beutler, Alison Burns, Wan-Ting He, Oliver Limbo, Chloe Smith, Sophie Ge Song, Jordan L Woehl, Linlin Yang, Robert K Abbott, Sean Callaghan, Elijah Garcia, Jonathan Hurtado, Mara Parren, Linghang Peng, Sydney I Ramirez, James Ricketts, Michael J Ricciardi, Stephen A Rawlings, Nicholas C Wu, Meng Yuan, Davey M Smith, David Nemazee, John R Teijaro, James E Voss, Ian A Wilson, Raiees Andrabi, Bryan Briney, Elise Landais, Devin Sok, Joseph G Jardine, Dennis R Burton
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model. Science (New York, N.Y.) 369 (6506) (2020)
Sandhya Bangaru, Gabriel Ozorowski, Hannah L Turner, Aleksandar Antanasijevic, Deli Huang, Xiaoning Wang, Jonathan L Torre, Jolene K Diedrich, Jing-Hui Tian, Alyse D Portnoff, Nita Patel, Michael J Massare, John Yates Iii, David Nemazee, James C Paulson, Greg Glenn, Gale Smith, Andrew B Ward
Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate. Science (New York, N.Y.) 370 (6520) (2020)
C Garrett Rappazzo, Longping V Tse, Chengzi I Kaku, Daniel Wrapp, Mrunal Sakharkar, Deli Huang, Laura M Deveau, Thomas J Yockachonis, Andrew S Herbert, Michael B Battles, Cecilia M O'Brien, Michael E Brown, James C Geoghegan, Jonathan Belk, Linghang Peng, Linlin Yang, Trevor D Scobey, Dennis R Burton, David Nemazee, John M Dye, James E Voss, Bronwyn M Gunn, Jason S Mclellan, Ralph S Baric, Lisa E Gralinski, Laura M Walker
An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19. bioRxiv : the preprint server for biology (2020)
Anna Z Wec, Daniel Wrapp, Andrew S Herbert, Daniel P Maurer, Denise Haslwanter, Mrunal Sakharkar, Rohit K Jangra, Maria Eugenia Dieterle, Asparouh Lilov, Deli Huang, Longping V Tse, Nicole V Johnson, Ching-Lin Hsieh, Nianshuang Wang, Juergen H Nett, Elizabeth Champney, Irina Burnina, Michael E Brown, Shu Lin, Melanie Sinclair, Carl Johnson, Sarat Pudi, Robert H Bortz, Ariel S Wirchnianski, Ethan Laudermilch, Catalina Florez, J Maximilian Fels, Cecilia M O'Brien, Barney S Graham, David Nemazee, Dennis R Burton, Ralph S Baric, James E Voss, Kartik Chandran, John M Dye, Jason S Mclellan, Laura M Walker
Broad neutralization of SARS-related viruses by human monoclonal antibodies. Science (New York, N.Y.) 369 (6504) (2020)
Aleksandar Antanasijevic, George Ueda, Philip J M Brouwer, Jeffrey Copps, Deli Huang, Joel D Allen, Christopher A Cottrell, Anila Yasmeen, Leigh M Sewall, Ilja Bontjer, Thomas J Ketas, Hannah L Turner, Zachary T Berndsen, David C Montefiori, Per Johan Klasse, Max Crispin, David Nemazee, John P Moore, Rogier W Sanders, Neil P King, Julien S Baker, Andrew B Ward
Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens. PLoS pathogens 16 (8) (2020)
Deli Huang, Jenny Tuyet Tran, Alex Olson, Thomas Vollbrecht, Mary Tenuta, Mariia V Guryleva, Roberta P Fuller, Torben Schiffner, Justin R Abadejos, Lauren Couvrette, Tanya R Blane, Karen Saye, Wenjuan Li, Elise Landais, Alicia Gonzalez-Martin, William R Schief, Ben Murrell, Dennis R Burton, David Nemazee, James E Voss
Author Correction: Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells. Nature communications 11 (1) (2020)
Deli Huang, Robert K Abbott, Colin Havenar-Daughton, Patrick D Skog, Rita Al-Kolla, Bettina Groschel, Tanya R Blane, Sergey Menis, Jenny Tuyet Tran, Theresa C Thinnes, Sabrina A Volpi, Alessia Liguori, Torben Schiffner, Sophia M Villegas, Oleksandr Kalyuzhniy, Mark Pintea, James E Voss, Nicole Phelps, Ryan Tingle, Alberto R Rodriguez, Greg Martin, Sergey Kupryianov, Allan deCamp, William R Schief, David Nemazee, Shane Crotty
B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models. Proceedings of the National Academy of Sciences of the United States of America 117 (37) (2020)
Deli Huang, Jenny Tuyet Tran, Alex Olson, Thomas Vollbrecht, Mary Tenuta, Mariia V Guryleva, Roberta P Fuller, Torben Schiffner, Justin R Abadejos, Lauren Couvrette, Tanya R Blane, Karen Saye, Wenjuan Li, Elise Landais, Alicia Gonzalez-Martin, William R Schief, Ben Murrell, Dennis R Burton, David Nemazee, James E Voss
Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells. Nature communications 11 (1) (2020)
Tara Bancroft, Blair L DeBuysscher, Connor Weidle, Allison Schwartz, Abigail Wall, Matthew D Gray, Junli Feng, Holly R Steach, Kristin S Fitzpatrick, Mesfin M Gewe, Patrick D Skog, Colleen Doyle-Cooper, Takayuki Ota, Roland K Strong, David Nemazee, Marie Pancera, Leonidas Stamatatos, Andrew T McGuire, Justin James Taylor
Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes. The Journal of experimental medicine 216 (10) (2019)
Linling He, Sonu Kumar, Joel D Allen, Deli Huang, Xiaohe Lin, Colin J Mann, Karen L Saye-Francisco, Jeffrey Copps, Anita Sarkar, Gabrielle S Blizard, Gabriel Ozorowski, Devin Sok, Max Crispin, Andrew B Ward, David Nemazee, Dennis R Burton, Ian A Wilson, Jiang Zhu
HIV-1 vaccine design through minimizing envelope metastability. Science advances 4 (11) (2018)
Amanda L Gavin, Deli Huang, Christoph Huber, Annica Mårtensson, Virginie Tardif, Patrick D Skog, Tanya R Blane, Therese C Thinnes, Kent Osborn, Hayley S Chong, Farnaz Kargaran, Phoebe Kimm, Armen Zeitjian, Rachel L Sielski, Megan Briggs, Sebastian R Schulz, Alessandro Zarpellon, Benjamin F Cravatt, Ee Shan Pang, John Teijaro, Juan Carlos de la Torre, Meredith O'Keeffe, Hubertus Hochrein, Markus Damme, Luc Teyton, Brian R Lawson, David Nemazee
PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing. Nature immunology 19 (9) (2018)
Max Medina-Ramírez, Fernando Garces, Amelia Escolano, Patrick D Skog, Steven W de Taeye, Ivan Del Moral-Sanchez, Andrew T McGuire, Anila Yasmeen, Anna-Janina Behrens, Gabriel Ozorowski, Tom L G M van den Kerkhof, Natalia T Freund, Pia Dosenovic, Yuanzi Hua, Alexander D Gitlin, Albert Cupo, Patricia van der Woude, Michael Golabek, Kwinten Sliepen, Tanya Blane, Neeltje A Kootstra, Mariëlle J van Breemen, Laura K Pritchard, Robyn L Stanfield, Max Crispin, Andrew B Ward, Leonidas Stamatatos, Per Johan Klasse, John P Moore, David Nemazee, Michel C Nussenzweig, Ian A Wilson, Rogier W Sanders
Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. The Journal of experimental medicine 214 (9) (2017)
Marianne M Martinic, Irina Caminschi, Meredith O'Keeffe, Therese C Thinnes, Raelene Grumont, Steve Gerondakis, Dianne B McKay, David Nemazee, Amanda L Gavin
The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8+ Thymocyte Selection. Journal of immunology (Baltimore, Md. : 1950) 198 (7) (2017)