The feasibility of a group stress management Liver SMART intervention for patients with end-stage liver disease: A pilot study.
Devika R JutagirRebecca M SaracinoAmy CunninghamKelly A Foran-TullerMary A DriscollWilliam H SledgeSukru H EmreDwain C FehonPublished in: Palliative & supportive care (2018)
Twenty-nine English-speaking United Network for Organ Sharing-registered patients with end-stage liver disease from a single transplantation center enrolled in 8-week, group cognitive-behavioral liver stress management and relaxation training intervention adapted for patients with end-stage liver disease. Patients completed pre- and postintervention surveys that included the Beck Depression Inventory II and the Beck Anxiety Inventory. Feasibility, acceptability, tolerability, and preliminary efficacy were assessed.ResultAttendance rate was 69.40%. The intervention was rated as "good" to "excellent" by 100% of participants who completed the postintervention survey in teaching them new skills to relax and to cope with stress, and by 94.12% of participants in helping them feel supported while waiting for a liver transplant. No adverse events were recorded over the course of treatment. Attrition was 13.79%. Anxious and depressive symptoms were not statistically different after the intervention.Significance of resultsThe liver stress management and relaxation training intervention is feasible, acceptable, and tolerable to end-stage liver disease patients within a transplant clinic setting. Anxious and depressive symptoms remained stable postintervention. Randomized controlled trials are needed to study the intervention's effectiveness in this population.
Keyphrases
- randomized controlled trial
- depressive symptoms
- end stage renal disease
- newly diagnosed
- ejection fraction
- study protocol
- clinical trial
- social support
- stress induced
- prognostic factors
- stem cells
- cross sectional
- single molecule
- heat stress
- mesenchymal stem cells
- open label
- cell therapy
- combination therapy
- double blind