Assessing the Effects of Nicotinamide Mononucleotide Supplementation on Pulmonary Inflammation in Male Mice Subchronically Exposed to Ambient Particulate Matter.

Rui ZhangShen ChenZiwei WangLizhu YeYue JiangMiao LiXinhang JiangHui PengZhanyu GuoLiping ChenRong ZhangYujie NiuMichael AschnerDaochuan LiWen Chen

Published in: Environmental health perspectives (2023)

Our novel findings suggest that NMN supplementation mitigated PM-induced lung injury by regulating immune functions and improving lipid metabolism in male mice, providing a putative intervention method for prevention of human health effects associated with PM exposure. https://doi.org/10.1289/EHP12259.

Keyphrases

particulate matter
air pollution
endothelial cells
high glucose
oxidative stress
randomized controlled trial
diabetic rats
pulmonary hypertension
induced pluripotent stem cells
pluripotent stem cells
drug induced
fatty acid
risk assessment
heavy metals