Expert opinion on drug metabolism & toxicology

Keyphrases

Publications

volume 20, number 4, 2024

Wenshu Li, Jiayi Mo, Zhilin Yang, Zhigang Zhao, Shenghui Mei
Risk factors associated with high-dose methotrexate induced toxicities. Expert opinion on drug metabolism & toxicology 20 (4) (2024)
Anna Wolska-Washer, Pawel Robak, Magdalena Witkowska, Tadeusz Robak
Metabolic and toxicological considerations of Bruton's tyrosine kinase inhibitors for the treatment of chronic lymphocytic leukemia/small lymphocytic lymphoma. Expert opinion on drug metabolism & toxicology 20 (4) (2024)
Justin M Eichinger, Divya M Shan, Jonathan D Greenzaid, Lisa Anakwenze, Steven R Feldman
Clinical pharmacokinetics and pharmacodynamics of oral systemic nonbiologic therapies for psoriasis patients. Expert opinion on drug metabolism & toxicology 20 (4) (2024)
Ajita Paliwal, Smita Jain, Sachin Kumar, Pranay Wal, Madhusmruti Khandai, Prasanna Shama Khandige, Vandana Sadananda, Md Khalid Anwer, Monica Gulati, Tapan Behl, Shriyansh Srivastava
Predictive Modelling in pharmacokinetics: from in-silico simulations to personalized medicine. Expert opinion on drug metabolism & toxicology 20 (4) (2024)
Kanchi Patell, Veronica Lee Mears, Michael H Storandt, Amit Mahipal
Metabolism, toxicity and management of fruquintinib: a novel drug for metastatic colorectal cancer. Expert opinion on drug metabolism & toxicology 20 (4) (2024)
Angela Lo, Jonathan D Greenzaid, Hannah Y Gantz, Kamran Chodri, Steven R Feldman
Clinical pharmacokinetics and pharmacodynamics of topical non-biological therapies for psoriasis patients. Expert opinion on drug metabolism & toxicology 20 (4) (2024)
Valeria Conti, Nicola Bertini, Rosaria Ricciardi, Berenice Stefanelli, Emanuela De Bellis, Carmine Sellitto, Marco Cascella, Francesco Sabbatino, Graziamaria Corbi, Pasquale Pagliano, Amelia Filippelli
Adverse events related to drug-drug interactions in COVID-19 patients. A persistent concern in the post-pandemic era: a systematic review. Expert opinion on drug metabolism & toxicology 20 (4) (2024)

volume 20, number 5, 2024

Shilan Mozaffari, Shekoufeh Nikfar, Mohammad Abdollahi
Pharmacokinetic considerations for drugs that treat diarrhea-predominant irritable bowel syndrome: what's new? Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Yaping Liu, Jiapeng Li, Hao-Jie Zhu
Regulation of carboxylesterases and its impact on pharmacokinetics and pharmacodynamics: an up-to-date review. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Hélène Verdoux, Clélia Quiles, Jose de Leon
Optimizing co-prescription of clozapine and antiseizure medications: a systematic review and expert recommendations for clinical practice. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Abrar K Thabit, Samaher Y Almoalim, Rahaf Altalhi
Cephalosporins with warfarin increase the risk of bleeding: myth or fact? Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Claudia Stöllberger, Josef Finsterer, Birke Schneider
Interactions between antiepileptic drugs and direct oral anticoagulants for primary and secondary stroke prevention. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Marcin Siwek, Anna Julia Krupa, Jarosław Woroń
Interactions between grapefruit juice and psychotropic medications: an update of the literature and an original case series. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Michael Camilleri, Kara Jencks
Pharmacogenetics in IBS: update and impact of GWAS studies in drug targets and metabolism. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Ilaria Faggiani, Ferdinando D'Amico, Francesca Bernardi, Sarah Bencardino, Mariangela Allocca, Federica Furfaro, Tommaso Lorenzo Parigi, Alessandra Zilli, Gionata Fiorino, Laurent Peyrin-Biroulet, Silvio Danese
Evaluating the pharmacokinetics of upadacitinib for the treatment of moderate-to-severe Crohn's disease. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Ayako Moriyama, Hinata Ueda, Katsuya Narumi, Shuho Asano, Ayako Furugen, Yoshitaka Saito, Masaki Kobayashi
Contribution of aldehyde oxidase to methotrexate-induced hepatotoxicity: in vitro and pharmacoepidemiological approaches. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Yaping Liu, Jiapeng Li, Hao-Jie Zhu
Regulation of carboxylesterases and its impact on pharmacokinetics and pharmacodynamics: an up-to-date review. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Ilaria Faggiani, Ferdinando D'Amico, Francesca Bernardi, Sarah Bencardino, Mariangela Allocca, Federica Furfaro, Tommaso Lorenzo Parigi, Alessandra Zilli, Gionata Fiorino, Laurent Peyrin-Biroulet, Silvio Danese
Evaluating the pharmacokinetics of upadacitinib for the treatment of moderate-to-severe Crohn's disease. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Shilan Mozaffari, Shekoufeh Nikfar, Mohammad Abdollahi
Pharmacokinetic considerations for drugs that treat diarrhea-predominant irritable bowel syndrome: what's new? Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Claudia Stöllberger, Josef Finsterer, Birke Schneider
Interactions between antiepileptic drugs and direct oral anticoagulants for primary and secondary stroke prevention. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Yaping Liu, Jiapeng Li, Hao-Jie Zhu
Regulation of carboxylesterases and its impact on pharmacokinetics and pharmacodynamics: an up-to-date review. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Michael Camilleri, Kara Jencks
Pharmacogenetics in IBS: update and impact of GWAS studies in drug targets and metabolism. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Michael Camilleri, Kara Jencks
Pharmacogenetics in IBS: update and impact of GWAS studies in drug targets and metabolism. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Ayako Moriyama, Hinata Ueda, Katsuya Narumi, Shuho Asano, Ayako Furugen, Yoshitaka Saito, Masaki Kobayashi
Contribution of aldehyde oxidase to methotrexate-induced hepatotoxicity: in vitro and pharmacoepidemiological approaches. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Marcin Siwek, Anna Julia Krupa, Jarosław Woroń
Interactions between grapefruit juice and psychotropic medications: an update of the literature and an original case series. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Yaping Liu, Jiapeng Li, Hao-Jie Zhu
Regulation of carboxylesterases and its impact on pharmacokinetics and pharmacodynamics: an up-to-date review. Expert opinion on drug metabolism & toxicology 20 (5) (2024)
Hélène Verdoux, Clélia Quiles, Jose de Leon
Optimizing co-prescription of clozapine and antiseizure medications: a systematic review and expert recommendations for clinical practice. Expert opinion on drug metabolism & toxicology 20 (5) (2024)

volume 20, number 6, 2024

Anne Kasten, Ingolf Cascorbi
Understanding the impact of ABCG2 polymorphisms on drug pharmacokinetics: focus on rosuvastatin and allopurinol. Expert opinion on drug metabolism & toxicology 20 (6) (2024)
Bassma Eltanameli, Janny Piñeiro-Llanes, Rodrigo Cristofoletti
Recent advances in cell-based in vitro models for predicting drug permeability across brain, intestinal, and pulmonary barriers. Expert opinion on drug metabolism & toxicology 20 (6) (2024)
Adile Orhan, Carolyn Nguyen, Alexandre Chan, Jørn Herrstedt
Pharmacokinetics, pharmacodynamics, safety, and tolerability of dopamine-receptor antagonists for the prevention of chemotherapy-induced nausea and vomiting. Expert opinion on drug metabolism & toxicology 20 (6) (2024)
Anne Kasten, Ingolf Cascorbi
Understanding the impact of ABCG2 polymorphisms on drug pharmacokinetics: focus on rosuvastatin and allopurinol. Expert opinion on drug metabolism & toxicology 20 (6) (2024)
Zoran Todorović, Gordana Dragović, Relja Lukić
Pharmacokinetic and toxicological considerations affecting antiretroviral drug dosing in pregnant women. Expert opinion on drug metabolism & toxicology 20 (6) (2024)
Alper Okyar, Dilek Ozturk Civelek, Yasemin Kubra Akyel, Saliha Surme, Zeliha Pala Kara, I Halil Kavakli
The role of the circadian timing system on drug metabolism and detoxification: an update. Expert opinion on drug metabolism & toxicology 20 (6) (2024)
Lorenzo Gasperoni, Emilio Francesco Giunta, Daniela Montanari, Carla Masini, Ugo De Giorgi
New-generation androgen receptor signaling inhibitors (ARSIs) in metastatic hormone-sensitive prostate cancer (mHSPC): pharmacokinetics, drug-drug interactions (DDIs), and clinical impact. Expert opinion on drug metabolism & toxicology 20 (6) (2024)
Gianluca D'Onofrio, Andrea Santangelo, Antonella Riva, Pasquale Striano
Genetic polymorphisms of drug-metabolizing enzymes in older and newer anti-seizure medications. Expert opinion on drug metabolism & toxicology 20 (6) (2024)
Lorenzo Gasperoni, Emilio Francesco Giunta, Daniela Montanari, Carla Masini, Ugo De Giorgi
New-generation androgen receptor signaling inhibitors (ARSIs) in metastatic hormone-sensitive prostate cancer (mHSPC): pharmacokinetics, drug-drug interactions (DDIs), and clinical impact. Expert opinion on drug metabolism & toxicology 20 (6) (2024)
Tanya Song, Yunfei Wang, Bret David Silverglate, George T Grossberg
Pharmacokinetic evaluation of donanemab for the treatment of Alzheimer's. Expert opinion on drug metabolism & toxicology 20 (6) (2024)
Mateo Gabriel Vasconez Martinez, Martin Frauenlob, Mario Rothbauer
An update on microfluidic multi-organ-on-a-chip systems for reproducing drug pharmacokinetics: the current state-of-the-art. Expert opinion on drug metabolism & toxicology 20 (6) (2024)
Tarang Jadav, Niraj Rajput, Hemant Kumar, Santosh Kumar Behera, Pinaki Sengupta
Induction effect of antiretroviral bictegravir on the expression of Abcb1, Abcg2 and Abcc1 genes associated with P-gp, BCRP and MRP1 transporters present in rat peripheral blood mononuclear cells. Expert opinion on drug metabolism & toxicology 20 (6) (2024)
Tarang Jadav, Niraj Rajput, Hemant Kumar, Santosh Kumar Behera, Pinaki Sengupta
Induction effect of antiretroviral bictegravir on the expression of Abcb1, Abcg2 and Abcc1 genes associated with P-gp, BCRP and MRP1 transporters present in rat peripheral blood mononuclear cells. Expert opinion on drug metabolism & toxicology 20 (6) (2024)

volume 20, number 7, 2024

Sushma Jadalannagari, Lorna Ewart
Beyond the hype and toward application: liver complex in vitro models in preclinical drug safety. Expert opinion on drug metabolism & toxicology 20 (7) (2024)
Ramkumar Menon, Lauren Richardson, Ananth Kumar Kammala
New approach methods on the bench side to accelerate clinical trials during pregnancy. Expert opinion on drug metabolism & toxicology 20 (7) (2024)
Xuan Xu, Jim E Riviere, Shahzad Raza, Nuwan Indika Millagaha Gedara, Remya Ampadi Ramachandran, Lisa A Tell, Gerald J Wyckoff, Majid Jaberi-Douraki
In-silico approaches to assessing multiple high-level drug-drug and drug-disease adverse drug effects. Expert opinion on drug metabolism & toxicology 20 (7) (2024)
Jie Liu, Md Kamrul Hasan Khan, Wenjing Guo, Fan Dong, Weigong Ge, Chaoyang Zhang, Ping Gong, Tucker A Patterson, Huixiao Hong
Machine learning and deep learning approaches for enhanced prediction of hERG blockade: a comprehensive QSAR modeling study. Expert opinion on drug metabolism & toxicology 20 (7) (2024)
Palle Helmke, Barbara Füzi, Gerhard F Ecker
Bioactivity descriptors for in vivo toxicity prediction: now and the future. Expert opinion on drug metabolism & toxicology 20 (7) (2024)
Kimberly Stratford, Jueichuan Connie Kang, Sheila M Healy, Zheng Tu, Luis G Valerio
Investigative analysis of blood-brain barrier penetrating potential of electronic nicotine delivery systems (e-cigarettes) chemicals using predictive computational models. Expert opinion on drug metabolism & toxicology 20 (7) (2024)
Jyotshna Kanungo, Barbara C Sorkin, Julie Krzykwa, Constance A Mitchell, Michelle Embry, Peter Spencer, G Jean Harry, Jason Cannon, Fang Liu, Christopher A McPherson, Stefan Gafner, Remco H S Westerink
Screening tools to evaluate the neurotoxic potential of botanicals: building a strategy to assess safety. Expert opinion on drug metabolism & toxicology 20 (7) (2024)
Yong Cheol Shin, Nam Than, Soo Jin Park, Hyun Jung Kim
Bioengineered human gut-on-a-chip for advancing non-clinical pharmaco-toxicology. Expert opinion on drug metabolism & toxicology 20 (7) (2024)
Camilla Alexander-White
In NAMs we trust - an innovative paradigm-shift in risk-based chemicals management for globally harmonized protection goals. Expert opinion on drug metabolism & toxicology 20 (7) (2024)
Nguyen Quoc Khanh Le, Thi-Xuan Tran, Phung-Anh Nguyen, Trang-Thi Ho, Van-Nui Nguyen
Recent progress in machine learning approaches for predicting carcinogenicity in drug development. Expert opinion on drug metabolism & toxicology 20 (7) (2024)