Andrea N Edginton (Andrea Edginton)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 55

Top Topics

Preterm Infants

Gold Nanoparticles

Top Venues

Haemophilia : the official journal of the World Federation of Hemophilia

Clinical pharmacokinetics

CPT: pharmacometrics & systems pharmacology

This page only lists publications with an associated author ORCID identifier.

Publications

Pierre Chelle, Dagmar Hajducek, Karen Thibaudeau, Nicholas Hobson, Alfonso Iorio, Amy D Shapiro, Andrea N Edginton
Development of a Plasminogen Population PK model supporting prophylactic replacement therapy for Plasminogen deficient patients within the WAPPS-Hemo platform. Haemophilia : the official journal of the World Federation of Hemophilia (2024)
Min-Soo Kim, Dagmar M Hajducek, James C Gilbert, Alfonso Iorio, Bernd Jilma, Andrea N Edginton
Kinetic Modeling for BT200 to Predict the Level of Plasma-Derived Coagulation Factor VIII in Humans. The AAPS journal 26 (4) (2024)
Elizabeth J Thompson, Angela Jeong, Victória Etges Helfer, Valentina Shakhnovich, Andrea N Edginton, Stephen J Balevic, Laura P James, David N Collier, Ravinder Anand, Daniel Gonzalez, null null
Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population. CPT: pharmacometrics & systems pharmacology (2024)
Elizabeth J Thompson, Angela Jeong, Victória Etges Helfer, Valentina Shakhnovich, Andrea N Edginton, Stephen J Balevic, Laura P James, David N Collier, Ravinder Anand, Daniel Gonzalez, null null
Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Patricia D Maglalang, Jaydeep Sinha, Kanecia O Zimmerman, Sean McCann, Andrea N Edginton, Christoph P Hornik, Chi D Hornik, William J Muller, Amira Al-Uzri, Marisa Meyer, Jia-Yuh Chen, Ravinder Anand, Eliana M Perrin, Daniel Gonzalez, null null
Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population. Clinical pharmacokinetics 63 (6) (2024)
Patricia D Maglalang, Jaydeep Sinha, Kanecia O Zimmerman, Sean McCann, Andrea N Edginton, Christoph P Hornik, Chi D Hornik, William J Muller, Amira Al-Uzri, Marisa Meyer, Jia-Yuh Chen, Ravinder Anand, Eliana M Perrin, Daniel Gonzalez, null null
Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population. Clinical pharmacokinetics (2024)
Patricia D Maglalang, Jaydeep Sinha, Kanecia O Zimmerman, Sean McCann, Andrea N Edginton, Christoph P Hornik, Chi D Hornik, William J Muller, Amira Al-Uzri, Marisa Meyer, Jia-Yuh Chen, Ravinder Anand, Eliana M Perrin, Daniel Gonzalez, null null
Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population. Clinical pharmacokinetics 63 (6) (2024)
Min-Soo Kim, Dagmar M Hajducek, James C Gilbert, Alfonso Iorio, Bernd Jilma, Andrea N Edginton
Kinetic Modeling for BT200 to Predict the Level of Plasma-Derived Coagulation Factor VIII in Humans. The AAPS journal 26 (4) (2024)
Pierre Chelle, Dagmar Hajducek, Karen Thibaudeau, Nicholas Hobson, Alfonso Iorio, Amy D Shapiro, Andrea N Edginton
Development of a Plasminogen Population PK model supporting prophylactic replacement therapy for Plasminogen deficient patients within the WAPPS-Hemo platform. Haemophilia : the official journal of the World Federation of Hemophilia 30 (4) (2024)
Cindy H T Yeung, Julie Autmizguine, Pooja Dalvi, Audrey Denoncourt, Shinya Ito, Pamela Katz, Mehzabin Rahman, Yves Theoret, Andrea N Edginton
Maternal Ezetimibe Concentrations Measured in Breast Milk and Its Use in Breastfeeding Infant Exposure Predictions. Clinical pharmacokinetics (2024)
Elizabeth J Thompson, Angela Jeong, Victória Etges Helfer, Valentina Shakhnovich, Andrea N Edginton, Stephen J Balevic, Laura P James, David N Collier, Ravinder Anand, Daniel Gonzalez, null null
Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Min-Soo Kim, Dagmar M Hajducek, James C Gilbert, Alfonso Iorio, Bernd Jilma, Andrea N Edginton
Kinetic Modeling for BT200 to Predict the Level of Plasma-Derived Coagulation Factor VIII in Humans. The AAPS journal 26 (4) (2024)
Davide Matino, Federico Germini, Anthony K C Chan, Kay Decker, Emma Iserman, Pierre Chelle, Andrea N Edginton, Olayide Oladoyinbo, Elisabetta Trinari, Arun Keepanasseril, Alfonso Iorio
Canadian clinical experience on switching from standard half-life recombinant factor VIII (rFVIII), octocog alfa, to extended half-life rFVIII, damoctocog alfa pegol, in persons with haemophilia A ≥ 12 years followed in a Comprehensive Hemophilia Care Program in Canada. Haemophilia : the official journal of the World Federation of Hemophilia (2024)
Davide Matino, Federico Germini, Anthony K C Chan, Kay Decker, Emma Iserman, Pierre Chelle, Andrea N Edginton, Olayide Oladoyinbo, Elisabetta Trinari, Arun Keepanasseril, Alfonso Iorio
Canadian clinical experience on switching from standard half-life recombinant factor VIII (rFVIII), octocog alfa, to extended half-life rFVIII, damoctocog alfa pegol, in persons with haemophilia A ≥ 12 years followed in a Comprehensive Hemophilia Care Program in Canada. Haemophilia : the official journal of the World Federation of Hemophilia 30 (2) (2024)
Dagmar M Hajducek, Pierre Chelle, Alfonso Iorio, Emma Iserman, Andrea N Edginton
Estimated prophylactic dose required to achieve 3% trough as a function of age and concentrate class in multi-country severe WAPPS-Hemo haemophilia patients. Haemophilia : the official journal of the World Federation of Hemophilia 30 (4) (2024)
Dagmar M Hajducek, Pierre Chelle, Alfonso Iorio, Emma Iserman, Andrea N Edginton
Estimated prophylactic dose required to achieve 3% trough as a function of age and concentrate class in multi-country severe WAPPS-Hemo haemophilia patients. Haemophilia : the official journal of the World Federation of Hemophilia (2024)
Elizabeth J Thompson, Angela Jeong, Victória Etges Helfer, Valentina Shakhnovich, Andrea N Edginton, Stephen J Balevic, Laura P James, David N Collier, Ravinder Anand, Daniel Gonzalez, null null
Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population. CPT: pharmacometrics & systems pharmacology (2024)
Sam Hirniak, Andrea N Edginton, Alfonso Iorio, Mhd Wasem Alsabbagh, Dagmar M Hajducek, William Wl Wong
Health utilities in adults with hemophilia A: A retrospective cohort study. Haemophilia : the official journal of the World Federation of Hemophilia (2024)
Elizabeth J Thompson, Angela Jeong, Victória Etges Helfer, Valentina Shakhnovich, Andrea N Edginton, Stephen J Balevic, Laura P James, David N Collier, Ravinder Anand, Daniel Gonzalez, null null
Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population. CPT: pharmacometrics & systems pharmacology (2024)
Elizabeth J Thompson, Angela Jeong, Victória Etges Helfer, Valentina Shakhnovich, Andrea N Edginton, Stephen J Balevic, Laura P James, David N Collier, Ravinder Anand, Daniel Gonzalez, null null
Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Sam Hirniak, Andrea N Edginton, Alfonso Iorio, Mhd Wasem Alsabbagh, Dagmar M Hajducek, William Wl Wong
Health utilities in adults with hemophilia A: A retrospective cohort study. Haemophilia : the official journal of the World Federation of Hemophilia 30 (3) (2024)
Eleni Karatza, Jaydeep Sinha, Patricia D Maglalang, Andrea N Edginton, Daniel Gonzalez
Physiologically-Based Pharmacokinetic Modeling of Total and Unbound Valproic Acid to Evaluate Dosing in Children With and Without Hypoalbuminemia. Clinical pharmacokinetics (2024)
Patricia D Maglalang, Jaydeep Sinha, Kanecia O Zimmerman, Sean McCann, Andrea N Edginton, Christoph P Hornik, Chi D Hornik, William J Muller, Amira Al-Uzri, Marisa Meyer, Jia-Yuh Chen, Ravinder Anand, Eliana M Perrin, Daniel Gonzalez, null null
Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population. Clinical pharmacokinetics 63 (6) (2024)
Cindy H T Yeung, Julie Autmizguine, Pooja Dalvi, Audrey Denoncourt, Shinya Ito, Pamela Katz, Mehzabin Rahman, Yves Theoret, Andrea N Edginton
Maternal Ezetimibe Concentrations Measured in Breast Milk and Its Use in Breastfeeding Infant Exposure Predictions. Clinical pharmacokinetics 63 (3) (2024)
Cindy H T Yeung, Julie Autmizguine, Pooja Dalvi, Audrey Denoncourt, Shinya Ito, Pamela Katz, Mehzabin Rahman, Yves Theoret, Andrea N Edginton
Maternal Ezetimibe Concentrations Measured in Breast Milk and Its Use in Breastfeeding Infant Exposure Predictions. Clinical pharmacokinetics 63 (3) (2024)
Elizabeth J Thompson, Angela Jeong, Victória Etges Helfer, Valentina Shakhnovich, Andrea N Edginton, Stephen J Balevic, Laura P James, David N Collier, Ravinder Anand, Daniel Gonzalez, null null
Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population. CPT: pharmacometrics & systems pharmacology (2024)
Cindy H T Yeung, Julie Autmizguine, Pooja Dalvi, Audrey Denoncourt, Shinya Ito, Pamela Katz, Mehzabin Rahman, Yves Theoret, Andrea N Edginton
Maternal Ezetimibe Concentrations Measured in Breast Milk and Its Use in Breastfeeding Infant Exposure Predictions. Clinical pharmacokinetics 63 (3) (2024)
Pierre Chelle, Dagmar Hajducek, Karen Thibaudeau, Nicholas Hobson, Alfonso Iorio, Amy D Shapiro, Andrea N Edginton
Development of a Plasminogen Population PK model supporting prophylactic replacement therapy for Plasminogen deficient patients within the WAPPS-Hemo platform. Haemophilia : the official journal of the World Federation of Hemophilia 30 (4) (2024)
Elizabeth J Thompson, Angela Jeong, Victória Etges Helfer, Valentina Shakhnovich, Andrea N Edginton, Stephen J Balevic, Laura P James, David N Collier, Ravinder Anand, Daniel Gonzalez, null null
Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population. CPT: pharmacometrics & systems pharmacology (2024)
Patricia D Maglalang, Jaydeep Sinha, Kanecia O Zimmerman, Sean McCann, Andrea N Edginton, Christoph P Hornik, Chi D Hornik, William J Muller, Amira Al-Uzri, Marisa Meyer, Jia-Yuh Chen, Ravinder Anand, Eliana M Perrin, Daniel Gonzalez, null null
Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population. Clinical pharmacokinetics (2024)
Davide Matino, Federico Germini, Anthony K C Chan, Kay Decker, Emma Iserman, Pierre Chelle, Andrea N Edginton, Olayide Oladoyinbo, Elisabetta Trinari, Arun Keepanasseril, Alfonso Iorio
Canadian clinical experience on switching from standard half-life recombinant factor VIII (rFVIII), octocog alfa, to extended half-life rFVIII, damoctocog alfa pegol, in persons with haemophilia A ≥ 12 years followed in a Comprehensive Hemophilia Care Program in Canada. Haemophilia : the official journal of the World Federation of Hemophilia 30 (2) (2024)
Davide Matino, Federico Germini, Anthony K C Chan, Kay Decker, Emma Iserman, Pierre Chelle, Andrea N Edginton, Olayide Oladoyinbo, Elisabetta Trinari, Arun Keepanasseril, Alfonso Iorio
Canadian clinical experience on switching from standard half-life recombinant factor VIII (rFVIII), octocog alfa, to extended half-life rFVIII, damoctocog alfa pegol, in persons with haemophilia A ≥ 12 years followed in a Comprehensive Hemophilia Care Program in Canada. Haemophilia : the official journal of the World Federation of Hemophilia (2024)
Keyur R Parmar, Pradeep B Lukka, Santosh Wagh, Zaid H Temrikar, Jiuyu Liu, Richard E Lee, Miriam Braunstein, Anthony J Hickey, Gregory Thomas Robertson, Mercedes Gonzalez-Juarrero, Andrea N Edginton, Bernd Meibohm
Development of a Minimalistic Physiologically Based Pharmacokinetic (mPBPK) Model for the Preclinical Development of Spectinamide Antibiotics. Pharmaceutics 15 (6) (2023)
Cindy H T Yeung, Kerri A Bertrand, Brookie M Best, Edmund Capparelli, Christina D Chambers, Dagmar M Hajducek, Abdullah Hamadeh, Shinya Ito, Jeremiah D Momper, Andrea N Edginton
Cannabidiol Exposure Through Maternal Marijuana Use: Predictions in Breastfed Infants. Clinical pharmacokinetics (2023)
Abdullah Hamadeh, Abdulkarim Najjar, John A Troutman, Andrea N Edginton
Enhancement of Skin Permeability Prediction through PBPK Modeling, Bayesian Inference, and Experiment Design. Pharmaceutics 15 (12) (2023)
Keyur R Parmar, Pradeep B Lukka, Santosh Wagh, Zaid H Temrikar, Jiuyu Liu, Richard E Lee, Miriam Braunstein, Anthony J Hickey, Gregory Thomas Robertson, Mercedes Gonzalez-Juarrero, Andrea N Edginton, Bernd Meibohm
Development of a Minimalistic Physiologically Based Pharmacokinetic (mPBPK) Model for the Preclinical Development of Spectinamide Antibiotics. Pharmaceutics 15 (6) (2023)
Abdullah Hamadeh, Abdulkarim Najjar, John A Troutman, Andrea N Edginton
Enhancement of Skin Permeability Prediction through PBPK Modeling, Bayesian Inference, and Experiment Design. Pharmaceutics 15 (12) (2023)
Mariana Guimarães, Anil Maharaj, Andrea N Edginton, Maria Vertzoni, Nikoletta Fotaki
Understanding the Impact of Age-Related Changes in Pediatric GI Solubility by Multivariate Data Analysis. Pharmaceutics 14 (2) (2022)
Jacqueline G Gerhart, Fernando O Carreño, Jennifer Lynn Ford, Andrea N Edginton, Eliana M Perrin, Kevin M Watt, William J Muller, Andrew M Atz, Amira Al-Uzri, Paula Delmore, Daniel Gonzalez, null null
Use of physiologically-based pharmacokinetic modeling to inform dosing of the opioid analgesics fentanyl and methadone in children with obesity. CPT: pharmacometrics & systems pharmacology 11 (6) (2022)
Samuel Dubinsky, Paul Malik, Dagmar M Hajducek, Andrea N Edginton
Determining the Effects of Chronic Kidney Disease on Organic Anion Transporter1/3 Activity Through Physiologically Based Pharmacokinetic Modeling. Clinical pharmacokinetics 61 (7) (2022)
Jacqueline G Gerhart, Fernando O Carreño, Matthew Shane Loop, And Craig R Lee, Andrea N Edginton, Jaydeep Sinha, Karan R Kumar, Carl M J Kirkpatrick, Christoph P Hornik, Daniel Gonzalez, null null
Use of Real-World Data and Physiologically-Based Pharmacokinetic Modeling to Characterize Enoxaparin Disposition in Children With Obesity. Clinical pharmacology and therapeutics 112 (2) (2022)
Yejin Esther Yun, Daniella Calderon-Nieva, Abdullah Hamadeh, Andrea N Edginton
Development and Evaluation of an In Silico Dermal Absorption Model Relevant for Children. Pharmaceutics 14 (1) (2022)
Pierre Chelle, Alfonso Iorio, Andrea N Edginton
A personalized limited sampling approach to better estimate terminal half-life of FVIII concentrates. Journal of thrombosis and haemostasis : JTH 20 (9) (2022)
Paul R V Malik, Abdullah Hamadeh, Andrea N Edginton
Model-Based Assessment of the Contribution of Monocytes and Macrophages to the Pharmacokinetics of Monoclonal Antibodies. Pharmaceutical research 39 (2) (2022)
Samuel Dubinsky, Kevin Watt, Steven Saleeb, Bilal Ahmed, Caitlin Carter, Cindy H T Yeung, Andrea N Edginton
Pharmacokinetics of Commonly Used Medications in Children Receiving Continuous Renal Replacement Therapy: A Systematic Review of Current Literature. Clinical pharmacokinetics (2021)
Jacky K Yu, Alfonso Iorio, Pierre Chelle, Andrea N Edginton
Pharmacokinetic implications of dosing emicizumab based on vial size: A simulation study. Haemophilia : the official journal of the World Federation of Hemophilia 27 (3) (2021)
Olav Versloot, Emma Iserman, Pierre Chelle, Federico Germini, Andrea N Edginton, Roger E G Schutgens, Alfonso Iorio, Kathelijn Fischer, null null
Terminal half-life of FVIII and FIX according to age, blood group and concentrate type: Data from the WAPPS database. Journal of thrombosis and haemostasis : JTH 19 (8) (2021)
Abdullah Hamadeh, John A Troutman, Andrea N Edginton
Assessment of Vehicle Volatility and Deposition Layer Thickness in Skin Penetration Models. Pharmaceutics 13 (6) (2021)
Cindy H T Yeung, Simon Fong, Paul R V Malik, Andrea N Edginton
Quantifying breast milk intake by term and preterm infants for input into paediatric physiologically based pharmacokinetic models. Maternal & child nutrition 16 (2) (2020)
Dagmar M Hajducek, Pierre Chelle, Cedric Hermans, Alfonso Iorio, Alanna McEneny-King, Jacky Yu, Andrea N Edginton
Development and evaluation of the population pharmacokinetic models for FVIII and FIX concentrates of the WAPPS-Hemo project. Haemophilia : the official journal of the World Federation of Hemophilia 26 (3) (2020)
Mohamed Aborig, Paul R V Malik, Shruti Nambiar, Pierre Chelle, Johnson Darko, Anthony J Mutsaers, Andrea N Edginton, Andre Fleck, Ernest Osei, Shawn D Wettig
Biodistribution and Physiologically-Based Pharmacokinetic Modeling of Gold Nanoparticles in Mice with Interspecies Extrapolation. Pharmaceutics 11 (4) (2019)
Alanna McEneny-King, Pierre Chelle, Séverine Henrard, Cedric Hermans, Alfonso Iorio, Andrea N Edginton
Modeling of Body Weight Metrics for Effective and Cost-Efficient Conventional Factor VIII Dosing in Hemophilia A Prophylaxis. Pharmaceutics 9 (4) (2017)
Paul Malik, Colin Phipps, Andrea N Edginton, Jonathan Blay
Pharmacokinetic Considerations for Antibody-Drug Conjugates against Cancer. Pharmaceutical research 34 (12) (2017)
Alanna McEneny-King, Gary Foster, Alfonso Iorio, Andrea N Edginton
Data Analysis Protocol for the Development and Evaluation of Population Pharmacokinetic Models for Incorporation Into the Web-Accessible Population Pharmacokinetic Service - Hemophilia (WAPPS-Hemo). JMIR research protocols 5 (4) (2016)
Alfonso Iorio, Arun Keepanasseril, Gary Foster, Tamara Navarro, Alanna McEneny-King, Andrea N Edginton, Lehana Thabane, null null
Development of a Web-Accessible Population Pharmacokinetic Service-Hemophilia (WAPPS-Hemo): Study Protocol. JMIR research protocols 5 (4) (2016)