A James Link

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 55

Top Topics

Structural Basis

Top Venues

ACS chemical biology

Journal of the American Chemical Society

ACS infectious diseases

This page only lists publications with an associated author ORCID identifier.

Publications

Drew V Carson, Reecan J Juarez, Truc Do, Zhongyue J Yang, A James Link
Antimicrobial Lasso Peptide Cloacaenodin Utilizes a Unique TonB-Dependent Transporter to Access Susceptible Bacteria. ACS chemical biology 19 (4) (2024)
Fernando Baquero, Konstantinos Beis, David J Craik, Yanyan Li, A James Link, Sylvie Rebuffat, Raúl Salomón, Konstantin Severinov, Séverine Zirah, Julian D Hegemann
The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide. Natural product reports 41 (3) (2024)
Fernando Baquero, Konstantinos Beis, David J Craik, Yanyan Li, A James Link, Sylvie Rebuffat, Raúl Salomón, Konstantin Severinov, Séverine Zirah, Julian D Hegemann
The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide. Natural product reports (2024)
Drew V Carson, Reecan J Juarez, Truc Do, Zhongyue J Yang, A James Link
Antimicrobial Lasso Peptide Cloacaenodin Utilizes a Unique TonB-Dependent Transporter to Access Susceptible Bacteria. ACS chemical biology 19 (4) (2024)
Drew V Carson, Reecan J Juarez, Truc Do, Zhongyue J Yang, A James Link
Antimicrobial Lasso Peptide Cloacaenodin Utilizes a Unique TonB-Dependent Transporter to Access Susceptible Bacteria. ACS chemical biology 19 (4) (2024)
Drew V Carson, Reecan J Juarez, Truc Do, Zhongyue J Yang, A James Link
Antimicrobial Lasso Peptide Cloacaenodin Utilizes a Unique TonB-Dependent Transporter to Access Susceptible Bacteria. ACS chemical biology 19 (4) (2024)
Brian Choi, Arthur Acuña, A James Link
Cyclic Peptides from Graspetide Biosynthesis and Native Chemical Ligation. Journal of the American Chemical Society 146 (17) (2024)
Brian Choi, Arthur Acuña, A James Link
Cyclic Peptides from Graspetide Biosynthesis and Native Chemical Ligation. Journal of the American Chemical Society (2024)
Fernando Baquero, Konstantinos Beis, David J Craik, Yanyan Li, A James Link, Sylvie Rebuffat, Raúl Salomón, Konstantin Severinov, Séverine Zirah, Julian D Hegemann
The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide. Natural product reports 41 (3) (2024)
Drew V Carson, Reecan J Juarez, Truc Do, Zhongyue J Yang, A James Link
Antimicrobial Lasso Peptide Cloacaenodin Utilizes a Unique TonB-Dependent Transporter to Access Susceptible Bacteria. ACS chemical biology (2024)
Brian Choi, Arthur Acuña, A James Link
Cyclic Peptides from Graspetide Biosynthesis and Native Chemical Ligation. Journal of the American Chemical Society 146 (17) (2024)
Drew V Carson, Reecan J Juarez, Truc Do, Zhongyue J Yang, A James Link
Antimicrobial Lasso Peptide Cloacaenodin Utilizes a Unique TonB-Dependent Transporter to Access Susceptible Bacteria. ACS chemical biology 19 (4) (2024)
Brian Choi, Arthur Acuña, A James Link
Cyclic Peptides from Graspetide Biosynthesis and Native Chemical Ligation. Journal of the American Chemical Society 146 (17) (2024)
Drew V Carson, Reecan J Juarez, Truc Do, Zhongyue J Yang, A James Link
Antimicrobial Lasso Peptide Cloacaenodin Utilizes a Unique TonB-Dependent Transporter to Access Susceptible Bacteria. ACS chemical biology 19 (4) (2024)
Drew V Carson, Reecan J Juarez, Truc Do, Zhongyue J Yang, A James Link
Antimicrobial Lasso Peptide Cloacaenodin Utilizes a Unique TonB-Dependent Transporter to Access Susceptible Bacteria. ACS chemical biology 19 (4) (2024)
Li Cao, Hader E Elashal, A James Link
Kinetics of Aspartimide Formation and Hydrolysis in Lasso Peptide Lihuanodin. Biochemistry 62 (3) (2023)
Li Cao, Hader E Elashal, A James Link
Kinetics of Aspartimide Formation and Hydrolysis in Lasso Peptide Lihuanodin. Biochemistry 62 (3) (2023)
Reecan J Juarez, Yaoyukun Jiang, Matthew Tremblay, Qianzhen Shao, A James Link, Zhongyue J Yang
LassoHTP: A High-Throughput Computational Tool for Lasso Peptide Structure Construction and Modeling. Journal of chemical information and modeling 63 (2) (2023)
Reecan J Juarez, Yaoyukun Jiang, Matthew Tremblay, Qianzhen Shao, A James Link, Zhongyue J Yang
LassoHTP: A High-Throughput Computational Tool for Lasso Peptide Structure Construction and Modeling. Journal of chemical information and modeling 63 (2) (2023)
Brian Choi, Arthur Acuña, Joseph D Koos, A James Link
Large-scale Bioinformatic Study of Graspimiditides and Structural Characterization of Albusimiditide. ACS chemical biology (2023)
Li Cao, Hader E Elashal, A James Link
Kinetics of Aspartimide Formation and Hydrolysis in Lasso Peptide Lihuanodin. Biochemistry 62 (3) (2023)
Drew V Carson, Yi Zhang, Larry So, Wai Ling Cheung-Lee, Alexis Jaramillo Cartagena, Seth A Darst, A James Link
Discovery, Characterization, and Bioactivity of the Achromonodins: Lasso Peptides Encoded by Achromobacter . Journal of natural products (2023)
Li Cao, Hader E Elashal, A James Link
Kinetics of Aspartimide Formation and Hydrolysis in Lasso Peptide Lihuanodin. Biochemistry (2023)
Li Cao, Truc Do, Angela D Zhu, Nathan Alam, A James Link
Genome Mining and Discovery of Imiditides, a Novel Family of RiPPs with a Class-defining Aspartimide Modification. bioRxiv : the preprint server for biology (2023)
Li Cao, Hader E Elashal, A James Link
Kinetics of Aspartimide Formation and Hydrolysis in Lasso Peptide Lihuanodin. Biochemistry 62 (3) (2023)
Alina Thokkadam, Truc Do, Xinchun Ran, Mark P Brynildsen, Zhongyue J Yang, A James Link
High-Throughput Screen Reveals the Structure-Activity Relationship of the Antimicrobial Lasso Peptide Ubonodin. ACS central science 9 (3) (2023)
Li Cao, Truc Do, Angela Zhu, Jianshu Duan, Nathan Alam, A James Link
Genome Mining and Discovery of Imiditides, a Family of RiPPs with a Class-Defining Aspartimide Modification. Journal of the American Chemical Society (2023)
Li Cao, Hader E Elashal, A James Link
Kinetics of Aspartimide Formation and Hydrolysis in Lasso Peptide Lihuanodin. Biochemistry 62 (3) (2023)
Reecan J Juarez, Yaoyukun Jiang, Matthew Tremblay, Qianzhen Shao, A James Link, Zhongyue J Yang
LassoHTP: A High-Throughput Computational Tool for Lasso Peptide Structure Construction and Modeling. Journal of chemical information and modeling 63 (2) (2023)
Reecan J Juarez, Yaoyukun Jiang, Matthew Tremblay, Qianzhen Shao, A James Link, Zhongyue J Yang
LassoHTP: A High-Throughput Computational Tool for Lasso Peptide Structure Construction and Modeling. Journal of chemical information and modeling (2023)
Alina Thokkadam, Truc Do, Xinchun Ran, Mark P Brynildsen, Zhongyue J Yang, A James Link
High-Throughput Screen Reveals the Structure-Activity Relationship of the Antimicrobial Lasso Peptide Ubonodin. ACS central science 9 (3) (2023)
Drew V Carson, Monica Patiño, Hader E Elashal, Alexis Jaramillo Cartagena, Yi Zhang, Megan E Whitley, Larry So, Angelo K Kayser-Browne, Ashlee M Earl, Roby P Bhattacharyya, A James Link
Cloacaenodin, an Antimicrobial Lasso Peptide with Activity against Enterobacter . ACS infectious diseases 9 (1) (2022)
Drew V Carson, Monica Patiño, Hader E Elashal, Alexis Jaramillo Cartagena, Yi Zhang, Megan E Whitley, Larry So, Angelo K Kayser-Browne, Ashlee M Earl, Roby P Bhattacharyya, A James Link
Cloacaenodin, an Antimicrobial Lasso Peptide with Activity against Enterobacter . ACS infectious diseases 9 (1) (2022)
Drew V Carson, Monica Patiño, Hader E Elashal, Alexis Jaramillo Cartagena, Yi Zhang, Megan E Whitley, Larry So, Angelo K Kayser-Browne, Ashlee M Earl, Roby P Bhattacharyya, A James Link
Cloacaenodin, an Antimicrobial Lasso Peptide with Activity against Enterobacter . ACS infectious diseases 9 (1) (2022)
Xuanqing Wan, A James Link, Mark P Brynildsen
Translational Fusion to Hmp Improves Heterologous Protein Expression. Microorganisms 10 (2) (2022)
Truc Do, A James Link
Protein Engineering in Ribosomally Synthesized and Post-translationally Modified Peptides (RiPPs). Biochemistry (2022)
Brian Choi, Hader E Elashal, Li Cao, A James Link
Mechanistic Analysis of the Biosynthesis of the Aspartimidylated Graspetide Amycolimiditide. Journal of the American Chemical Society 144 (47) (2022)
Drew V Carson, Monica Patiño, Hader E Elashal, Alexis Jaramillo Cartagena, Yi Zhang, Megan E Whitley, Larry So, Angelo K Kayser-Browne, Ashlee M Earl, Roby P Bhattacharyya, A James Link
Cloacaenodin, an Antimicrobial Lasso Peptide with Activity against Enterobacter . ACS infectious diseases 9 (1) (2022)
Truc Do, Alina Thokkadam, Robert Leach, A James Link
Phenotype-Guided Comparative Genomics Identifies the Complete Transport Pathway of the Antimicrobial Lasso Peptide Ubonodin in Burkholderia . ACS chemical biology 17 (8) (2022)
Drew V Carson, Monica Patiño, Hader E Elashal, Alexis Jaramillo Cartagena, Yi Zhang, Megan E Whitley, Larry So, Angelo K Kayser-Browne, Ashlee M Earl, Roby P Bhattacharyya, A James Link
Cloacaenodin, an Antimicrobial Lasso Peptide with Activity against Enterobacter . ACS infectious diseases 9 (1) (2022)
Hader E Elashal, Joseph D Koos, Wai Ling Cheung-Lee, Brian Choi, Li Cao, Michelle A Richardson, Heather L White, A James Link
Biosynthesis and characterization of fuscimiditide, an aspartimidylated graspetide. Nature chemistry 14 (11) (2022)
Drew V Carson, Monica Patiño, Hader E Elashal, Alexis Jaramillo Cartagena, Yi Zhang, Megan E Whitley, Larry So, Angelo K Kayser-Browne, Ashlee M Earl, Roby P Bhattacharyya, A James Link
Cloacaenodin, an Antimicrobial Lasso Peptide with Activity against Enterobacter . ACS infectious diseases (2022)
Li Cao, Truc Do, A James Link
Mechanisms of action of ribosomally synthesized and posttranslationally modified peptides (RiPPs). Journal of industrial microbiology & biotechnology 48 (3-4) (2021)
Li Cao, Moshe Beiser, Joseph D Koos, Margarita Orlova, Hader E Elashal, Hendrik V Schröder, A James Link
Cellulonodin-2 and Lihuanodin: Lasso Peptides with an Aspartimide Post-Translational Modification. Journal of the American Chemical Society 143 (30) (2021)
Hendrik V Schröder, Yi Zhang, A James Link
Dynamic covalent self-assembly of mechanically interlocked molecules solely made from peptides. Nature chemistry 13 (9) (2021)
Hendrik V Schröder, Michael Stadlmeier, Martin Wühr, A James Link
The Shuttling Cascade in Lasso Peptide Benenodin-1 is Controlled by Non-Covalent Interactions. Chemistry (Weinheim an der Bergstrasse, Germany) (2021)
Wai Ling Cheung-Lee, Madison E Parry, Chuhan Zong, Alexis Jaramillo Cartagena, Seth A Darst, Nancy D Connell, Riccardo Russo, A James Link
Discovery of Ubonodin, an Antimicrobial Lasso Peptide Active against Members of the Burkholderia cepacia Complex. Chembiochem : a European journal of chemical biology 21 (9) (2020)
Wai Ling Cheung-Lee, A James Link
Genome mining for lasso peptides: past, present, and future. Journal of industrial microbiology & biotechnology 46 (9-10) (2019)
Nathaniel R Braffman, Frank J Piscotta, Jesse Hauver, Elizabeth A Campbell, A James Link, Seth A Darst
Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proceedings of the National Academy of Sciences of the United States of America 116 (4) (2019)
Wai Ling Cheung-Lee, Madison E Parry, Alexis Jaramillo Cartagena, Seth A Darst, A James Link
Discovery and structure of the antimicrobial lasso peptide citrocin. The Journal of biological chemistry 294 (17) (2019)
Wai Ling Cheung-Lee, Li Cao, A James Link
Pandonodin: A Proteobacterial Lasso Peptide with an Exceptionally Long C-Terminal Tail. ACS chemical biology 14 (12) (2019)
Frank J Piscotta, Philip D Jeffrey, A James Link
ParST is a widespread toxin-antitoxin module that targets nucleotide metabolism. Proceedings of the National Academy of Sciences of the United States of America 116 (3) (2018)
Joseph D Koos, A James Link
Heterologous and in Vitro Reconstitution of Fuscanodin, a Lasso Peptide from Thermobifida fusca. Journal of the American Chemical Society 141 (2) (2018)
Chuhan Zong, Michelle J Wu, Jason Z Qin, A James Link
Lasso Peptide Benenodin-1 Is a Thermally Actuated [1]Rotaxane Switch. Journal of the American Chemical Society 139 (30) (2017)
Jonathan R Chekan, Joseph D Koos, Chuhan Zong, Mikhail O Maksimov, A James Link, Satish K Nair
Structure of the Lasso Peptide Isopeptidase Identifies a Topology for Processing Threaded Substrates. Journal of the American Chemical Society 138 (50) (2016)
Alan S Futran, Saw Kyin, Stanislav Y Shvartsman, A James Link
Mapping the binding interface of ERK and transcriptional repressor Capicua using photocrosslinking. Proceedings of the National Academy of Sciences of the United States of America 112 (28) (2015)
Mikhail O Maksimov, Joseph D Koos, Chuhan Zong, Bozhena Lisko, A James Link
Elucidating the Specificity Determinants of the AtxE2 Lasso Peptide Isopeptidase. The Journal of biological chemistry 290 (52) (2015)
A James Link
Biosynthesis: Leading the way to RiPPs. Nature chemical biology 11 (8) (2015)