David J Craik (David Craik, D J Craik)

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 160

Top Venues

Journal of medicinal chemistry

ACS chemical biology

Angewandte Chemie (International ed. in English)

Journal of natural products

This page only lists publications with an associated author ORCID identifier.

Publications

Fabian B H Rehm, Tristan J Tyler, Yan Zhou, Yen-Hua Huang, Conan K Wang, Nicole Lawrence, David J Craik, Thomas Durek
Repurposing a plant peptide cyclase for targeted lysine acylation. Nature chemistry (2024)
Yan Zhou, Thomas Durek, David J Craik, Fabian B H Rehm
Sortase-Catalyzed Protein Domain Inversion. Angewandte Chemie (International ed. in English) (2024)
Zhihao Jiang, Yen-Hua Huang, Quentin Kaas, David J Craik, Conan K Wang
Structure and Activity of Reconstructed Pseudo-Ancestral Cyclotides. ChemMedChem (2024)
Nicole Lawrence, Thomas N G Handley, Simon J de Veer, Maxim D Harding, Alicja Andraszek, Lachlan Hall, Karoline D Raven, Sandra Duffy, Vicky M Avery, David J Craik, Lara R Malins, Brendan J McMorran
Enhancing the Intrinsic Antiplasmodial Activity and Improving the Stability and Selectivity of a Tunable Peptide Scaffold Derived from Human Platelet Factor 4. ACS infectious diseases 10 (8) (2024)
Arik J Hone, Ulises Santiago, Peta J Harvey, Bassel Tekarli, Joanna Gajewiak, David J Craik, Carlos J Camacho, J Michael McIntosh
Design, Synthesis, and Structure-Activity Relationships of Novel Peptide Derivatives of the Severe Acute Respiratory Syndrome-Coronavirus-2 Spike-Protein that Potently Inhibit Nicotinic Acetylcholine Receptors. Journal of medicinal chemistry 67 (11) (2024)
Simon J de Veer, Yan Zhou, Thomas Durek, David J Craik, Fabian B H Rehm
Tertiary amide bond formation by an engineered asparaginyl ligase. Chemical science 15 (14) (2024)
Yan Zhou, Thomas Durek, David J Craik, Fabian B H Rehm
Sortase-Catalyzed Protein Domain Inversion. Angewandte Chemie (International ed. in English) 63 (14) (2024)
Arik J Hone, Ulises Santiago, Peta J Harvey, Bassel Tekarli, Joanna Gajewiak, David J Craik, Carlos J Camacho, J Michael McIntosh
Design, Synthesis, and Structure-Activity Relationships of Novel Peptide Derivatives of the Severe Acute Respiratory Syndrome-Coronavirus-2 Spike-Protein that Potently Inhibit Nicotinic Acetylcholine Receptors. Journal of medicinal chemistry (2024)
Fernando Baquero, Konstantinos Beis, David J Craik, Yanyan Li, A James Link, Sylvie Rebuffat, Raúl Salomón, Konstantin Severinov, Séverine Zirah, Julian D Hegemann
The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide. Natural product reports 41 (3) (2024)
Fabian B H Rehm, Tristan J Tyler, Yan Zhou, Yen-Hua Huang, Conan K Wang, Nicole Lawrence, David J Craik, Thomas Durek
Repurposing a plant peptide cyclase for targeted lysine acylation. Nature chemistry (2024)
Fernando Baquero, Konstantinos Beis, David J Craik, Yanyan Li, A James Link, Sylvie Rebuffat, Raúl Salomón, Konstantin Severinov, Séverine Zirah, Julian D Hegemann
The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide. Natural product reports (2024)
Yan Zhou, Thomas Durek, David J Craik, Fabian B H Rehm
Sortase-Catalyzed Protein Domain Inversion. Angewandte Chemie (International ed. in English) 63 (14) (2024)
Yan Zhou, Thomas Durek, David J Craik, Fabian B H Rehm
Sortase-Catalyzed Protein Domain Inversion. Angewandte Chemie (International ed. in English) 63 (14) (2024)
Fabian B H Rehm, Tristan J Tyler, Yan Zhou, Yen-Hua Huang, Conan K Wang, Nicole Lawrence, David J Craik, Thomas Durek
Repurposing a plant peptide cyclase for targeted lysine acylation. Nature chemistry (2024)
Fabian B H Rehm, Tristan J Tyler, Yan Zhou, Yen-Hua Huang, Conan K Wang, Nicole Lawrence, David J Craik, Thomas Durek
Author Correction: Repurposing a plant peptide cyclase for targeted lysine acylation. Nature chemistry (2024)
Fabian B H Rehm, Tristan J Tyler, Yan Zhou, Yen-Hua Huang, Conan K Wang, Nicole Lawrence, David J Craik, Thomas Durek
Author Correction: Repurposing a plant peptide cyclase for targeted lysine acylation. Nature chemistry (2024)
Nicole Lawrence, Thomas N G Handley, Simon J de Veer, Maxim D Harding, Alicja Andraszek, Lachlan Hall, Karoline D Raven, Sandra Duffy, Vicky M Avery, David J Craik, Lara R Malins, Brendan J McMorran
Enhancing the Intrinsic Antiplasmodial Activity and Improving the Stability and Selectivity of a Tunable Peptide Scaffold Derived from Human Platelet Factor 4. ACS infectious diseases (2024)
Grégoire Jean-Baptiste Philippe, Yen-Hua Huang, Anna Mittermeier, Christopher J Brown, Quentin Kaas, Siti Radhiah Ramlan, Conan K Wang, David Lane, Alexander Loewer, Sónia Troeira Henriques, David J Craik
Delivery to, and Reactivation of, the p53 Pathway in Cancer Cells Using a Grafted Cyclotide Conjugated with a Cell-Penetrating Peptide. Journal of medicinal chemistry (2024)
Grégoire Jean-Baptiste Philippe, Yen-Hua Huang, Anna Mittermeier, Christopher J Brown, Quentin Kaas, Siti Radhiah Ramlan, Conan K Wang, David Lane, Alexander Loewer, Sónia Troeira Henriques, David J Craik
Delivery to, and Reactivation of, the p53 Pathway in Cancer Cells Using a Grafted Cyclotide Conjugated with a Cell-Penetrating Peptide. Journal of medicinal chemistry 67 (2) (2024)
Simon J de Veer, Yan Zhou, Thomas Durek, David J Craik, Fabian B H Rehm
Tertiary amide bond formation by an engineered asparaginyl ligase. Chemical science 15 (14) (2024)
Fernando Baquero, Konstantinos Beis, David J Craik, Yanyan Li, A James Link, Sylvie Rebuffat, Raúl Salomón, Konstantin Severinov, Séverine Zirah, Julian D Hegemann
The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide. Natural product reports 41 (3) (2024)
Fabian B H Rehm, Tristan J Tyler, Yan Zhou, Yen-Hua Huang, Conan K Wang, Nicole Lawrence, David J Craik, Thomas Durek
Repurposing a plant peptide cyclase for targeted lysine acylation. Nature chemistry (2024)
Biswajit Biswas, Yen-Hua Huang, David J Craik, Conan K Wang
The prospect of substrate-based kinase inhibitors to improve target selectivity and overcome drug resistance. Chemical science 15 (33) (2024)
Fabian B H Rehm, Tristan J Tyler, Yan Zhou, Yen-Hua Huang, Conan K Wang, Nicole Lawrence, David J Craik, Thomas Durek
Author Correction: Repurposing a plant peptide cyclase for targeted lysine acylation. Nature chemistry (2024)
Edward K Gilding, Mark A Jackson, Linh T T Nguyen, Brett R Hamilton, Katherine A Farquharson, Wing L Ho, Kuok Yap, Carolyn J Hogg, Katherine Belov, David J Craik
Hijacking of N-fixing legume albumin-1 genes enables the cyclization and stabilization of defense peptides. Nature communications 15 (1) (2024)
Nicole Lawrence, Thomas N G Handley, Simon J de Veer, Maxim D Harding, Alicja Andraszek, Lachlan Hall, Karoline D Raven, Sandra Duffy, Vicky M Avery, David J Craik, Lara R Malins, Brendan J McMorran
Enhancing the Intrinsic Antiplasmodial Activity and Improving the Stability and Selectivity of a Tunable Peptide Scaffold Derived from Human Platelet Factor 4. ACS infectious diseases 10 (8) (2024)
Nicole Lawrence, Thomas N G Handley, Simon J de Veer, Maxim D Harding, Alicja Andraszek, Lachlan Hall, Karoline D Raven, Sandra Duffy, Vicky M Avery, David J Craik, Lara R Malins, Brendan J McMorran
Enhancing the Intrinsic Antiplasmodial Activity and Improving the Stability and Selectivity of a Tunable Peptide Scaffold Derived from Human Platelet Factor 4. ACS infectious diseases 10 (8) (2024)
Johannes Koehbach, Edin Muratspahić, Zakaria M Ahmed, Andrew M White, Nataša Tomašević, Thomas Durek, Richard J Clark, Christian W Gruber, David J Craik
Chemical synthesis of grafted cyclotides using a "plug and play" approach. RSC chemical biology 5 (6) (2024)
Johannes Koehbach, Edin Muratspahić, Zakaria M Ahmed, Andrew M White, Nataša Tomašević, Thomas Durek, Richard J Clark, Christian W Gruber, David J Craik
Chemical synthesis of grafted cyclotides using a "plug and play" approach. RSC chemical biology 5 (6) (2024)
Edward K Gilding, Mark A Jackson, Linh T T Nguyen, Brett R Hamilton, Katherine A Farquharson, Wing L Ho, Kuok Yap, Carolyn J Hogg, Katherine Belov, David J Craik
Hijacking of N-fixing legume albumin-1 genes enables the cyclization and stabilization of defense peptides. Nature communications 15 (1) (2024)
Negin Khatibi, Yen-Hua Huang, Conan K Wang, Thomas Durek, Edward K Gilding, David J Craik
Isolation and Characterization of Insecticidal Cyclotides from Viola communis . Journal of natural products (2024)
Grégoire Jean-Baptiste Philippe, Yen-Hua Huang, Anna Mittermeier, Christopher J Brown, Quentin Kaas, Siti Radhiah Ramlan, Conan K Wang, David Lane, Alexander Loewer, Sónia Troeira Henriques, David J Craik
Delivery to, and Reactivation of, the p53 Pathway in Cancer Cells Using a Grafted Cyclotide Conjugated with a Cell-Penetrating Peptide. Journal of medicinal chemistry 67 (2) (2024)
Zhihao Jiang, Yen-Hua Huang, Quentin Kaas, David J Craik, Conan K Wang
Structure and Activity of Reconstructed Pseudo-Ancestral Cyclotides. ChemMedChem 19 (14) (2024)
Biswajit Biswas, Yen-Hua Huang, David J Craik, Conan K Wang
The prospect of substrate-based kinase inhibitors to improve target selectivity and overcome drug resistance. Chemical science 15 (33) (2024)
Edin Muratspahić, Kristine Deibler, Jianming Han, Nataša Tomašević, Kirtikumar B Jadhav, Aina-Leonor Olivé-Marti, Nadine Hochrainer, Roland Hellinger, Johannes Koehbach, Jonathan F Fay, Mohammad Homaidur Rahman, Lamees Hegazy, Timothy W Craven, Balazs R Varga, Gaurav Bhardwaj, Kevin Appourchaux, Susruta Majumdar, Markus Muttenthaler, Parisa Hosseinzadeh, David J Craik, Mariana Spetea, Tao Che, Julien S Baker, Christian W Gruber
Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor. Nature communications 14 (1) (2023)
Tristan J Tyler, Thomas Durek, David J Craik
Native and Engineered Cyclic Disulfide-Rich Peptides as Drug Leads. Molecules (Basel, Switzerland) 28 (7) (2023)
Pan Xu, Panpan Zhang, Xiaopeng Zhu, Yong Wu, Peta J Harvey, Quentin Kaas, Dongting Zhangsun, David J Craik, Sulan Luo
Structure-Activity Relationships of Alanine Scan Mutants αO-Conotoxins GeXIVA[1,2] and GeXIVA[1,4]. Journal of medicinal chemistry (2023)
Linh T T Nguyen, David J Craik, Quentin Kaas
Bibliometric Review of the Literature on Cone Snail Peptide Toxins from 2000 to 2022. Marine drugs 21 (3) (2023)
Linh T T Nguyen, David J Craik, Quentin Kaas
Bibliometric Review of the Literature on Cone Snail Peptide Toxins from 2000 to 2022. Marine drugs 21 (3) (2023)
Xiaopeng Zhu, Shuai Wang, Quentin Kaas, Jinpeng Yu, Yong Wu, Peta J Harvey, Dongting Zhangsun, David J Craik, Sulan Luo
Discovery, Characterization, and Engineering of LvIC, an α4/4-Conotoxin That Selectively Blocks Rat α6/α3β4 Nicotinic Acetylcholine Receptors. Journal of medicinal chemistry 66 (3) (2023)
Mark A Jackson, Jing Xie, Linh T T Nguyen, Xiaohan Wang, Kuok Yap, Peta J Harvey, Edward K Gilding, David J Craik
Plant-based production of an orally active cyclotide for the treatment of multiple sclerosis. Transgenic research (2023)
Zhian Chen, Yanfang Cui, Yin Yao, Bo Liu, Joseph Yunis, Xin Gao, Naiqi Wang, Pablo F Cañete, Zewen Kelvin Tuong, Hongjian Sun, Hao Wang, Si-Ling Yang, Runli Wang, Yew Ann Leong, David Simon Davis, Jiahuan Qin, Kaili Liang, Jun Deng, Conan K Wang, Yen-Hua Huang, Jonathan A Roco, Sam Nettelfield, Huaming Zhu, Huajun Xu, Zhijia Yu, David J Craik, Zheng Liu, Hai Qi, Christopher R Parish, Di Yu
Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology 8 (80) (2023)
Zhian Chen, Yanfang Cui, Yin Yao, Bo Liu, Joseph Yunis, Xin Gao, Naiqi Wang, Pablo F Cañete, Zewen Kelvin Tuong, Hongjian Sun, Hao Wang, Si-Ling Yang, Runli Wang, Yew Ann Leong, David Simon Davis, Jiahuan Qin, Kaili Liang, Jun Deng, Conan K Wang, Yen-Hua Huang, Jonathan A Roco, Sam Nettelfield, Huaming Zhu, Huajun Xu, Zhijia Yu, David J Craik, Zheng Liu, Hai Qi, Christopher R Parish, Di Yu
Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology 8 (80) (2023)
Xiaorong Liu, Sónia T Henriques, David J Craik, Lai Yue Chan
Unlocking the Potential of the Antimicrobial Peptide Gomesin: From Discovery and Structure-Activity Relationships to Therapeutic Applications. International journal of molecular sciences 24 (6) (2023)
Edin Muratspahić, Despoina Aslanoglou, Andrew M White, Claudia Draxler, Xaver Kozisek, Zara Farooq, David J Craik, Peter J McCormick, Thomas Durek, Christian W Gruber
Development of Melanocortin 4 Receptor Agonists by Exploiting Animal-Derived Macrocyclic, Disulfide-Rich Peptide Scaffolds. ACS pharmacology & translational science 6 (10) (2023)
Xiaopeng Zhu, Shuai Wang, Quentin Kaas, Jinpeng Yu, Yong Wu, Peta J Harvey, Dongting Zhangsun, David J Craik, Sulan Luo
Discovery, Characterization, and Engineering of LvIC, an α4/4-Conotoxin That Selectively Blocks Rat α6/α3β4 Nicotinic Acetylcholine Receptors. Journal of medicinal chemistry 66 (3) (2023)
Edin Muratspahić, Andrew M White, Cosmin I Ciotu, Nadine Hochrainer, Nataša Tomašević, Johannes Koehbach, Richard James Lewis, Mariana Spetea, Michael J M Fischer, David J Craik, Christian W Gruber
Development of a Selective Peptide κ-Opioid Receptor Antagonist by Late-Stage Functionalization with Cysteine Staples. Journal of medicinal chemistry (2023)
Xiaorong Liu, Sónia T Henriques, David J Craik, Lai Yue Chan
Unlocking the Potential of the Antimicrobial Peptide Gomesin: From Discovery and Structure-Activity Relationships to Therapeutic Applications. International journal of molecular sciences 24 (6) (2023)
Abhishek Bajpai, Mark A Jackson, Yen-Hua Huang, Kuok Yap, Qingdan Du, Tevin Chui-Ying Chau, David J Craik, Edward K Gilding
Nematicidal Activity of Cyclotides: Toxicity Against Caenorhabditis elegans . Journal of natural products (2023)
Linh T T Nguyen, David J Craik, Quentin Kaas
Bibliometric Review of the Literature on Cone Snail Peptide Toxins from 2000 to 2022. Marine drugs 21 (3) (2023)
Xiaopeng Zhu, Shuai Wang, Quentin Kaas, Jinpeng Yu, Yong Wu, Peta J Harvey, Dongting Zhangsun, David J Craik, Sulan Luo
Discovery, Characterization, and Engineering of LvIC, an α4/4-Conotoxin That Selectively Blocks Rat α6/α3β4 Nicotinic Acetylcholine Receptors. Journal of medicinal chemistry 66 (3) (2023)
Nicole L van der Weerden, Kathy Parisi, James A McKenna, Brigitte M Hayes, Peta J Harvey, Pedro Quimbar, Sean R Wevrett, Prem K Veneer, Owen McCorkelle, Shaily Vasa, Rosemary Guarino, Simon Poon, Yolanda M Gaspar, Michael J Baker, David J Craik, Rob B Turner, Marc B Brown, Mark R Bleackley, Marilyn A Anderson
The Plant Defensin Ppdef1 Is a Novel Topical Treatment for Onychomycosis. Journal of fungi (Basel, Switzerland) 9 (11) (2023)
Linh T T Nguyen, David J Craik, Quentin Kaas
Bibliometric Review of the Literature on Cone Snail Peptide Toxins from 2000 to 2022. Marine drugs 21 (3) (2023)
Xiaorong Liu, Sónia T Henriques, David J Craik, Lai Yue Chan
Unlocking the Potential of the Antimicrobial Peptide Gomesin: From Discovery and Structure-Activity Relationships to Therapeutic Applications. International journal of molecular sciences 24 (6) (2023)
Isabella R Palombi, Nicole Lawrence, Andrew M White, Caitlin L Gare, David J Craik, Brendan J McMorran, Lara R Malins
Development of Antiplasmodial Peptide-Drug Conjugates Using a Human Protein-Derived Cell-Penetrating Peptide with Selectivity for Infected Cells. Bioconjugate chemistry (2023)
Xiaopeng Zhu, Shuai Wang, Quentin Kaas, Jinpeng Yu, Yong Wu, Peta J Harvey, Dongting Zhangsun, David J Craik, Sulan Luo
Discovery, Characterization, and Engineering of LvIC, an α4/4-Conotoxin That Selectively Blocks Rat α6/α3β4 Nicotinic Acetylcholine Receptors. Journal of medicinal chemistry (2023)
Zhian Chen, Yanfang Cui, Yin Yao, Bo Liu, Joseph Yunis, Xin Gao, Naiqi Wang, Pablo F Cañete, Zewen Kelvin Tuong, Hongjian Sun, Hao Wang, Si-Ling Yang, Runli Wang, Yew Ann Leong, David Simon Davis, Jiahuan Qin, Kaili Liang, Jun Deng, Conan K Wang, Yen-Hua Huang, Jonathan A Roco, Sam Nettelfield, Huaming Zhu, Huajun Xu, Zhijia Yu, David J Craik, Zheng Liu, Hai Qi, Christopher R Parish, Di Yu
Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology 8 (80) (2023)
Zhian Chen, Yanfang Cui, Yin Yao, Bo Liu, Joseph Yunis, Xin Gao, Naiqi Wang, Pablo F Cañete, Zewen Kelvin Tuong, Hongjian Sun, Hao Wang, Si-Ling Yang, Runli Wang, Yew Ann Leong, David Simon Davis, Jiahuan Qin, Kaili Liang, Jun Deng, Conan K Wang, Yen-Hua Huang, Jonathan A Roco, Sam Nettelfield, Huaming Zhu, Huajun Xu, Zhijia Yu, David J Craik, Zheng Liu, Hai Qi, Christopher R Parish, Di Yu
Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology 8 (80) (2023)
Kirsten L McMahon, Hue N T Tran, Jennifer R Deuis, David J Craik, Irina Vetter, Christina I Schroeder
µ-Conotoxins Targeting the Human Voltage-Gated Sodium Channel Subtype Na V 1.7. Toxins 14 (9) (2022)
Fabian B H Rehm, Tristan J Tyler, Simon J de Veer, David J Craik, Thomas Durek
Enzymatic C-to-C Protein Ligation. Angewandte Chemie (International ed. in English) 61 (11) (2022)
Choi Yi Li, Fabian B H Rehm, Kuok Yap, Christina N Zdenek, Maxim D Harding, Bryan G Fry, Thomas Durek, David J Craik, Simon J de Veer
Cystine Knot Peptides with Tuneable Activity and Mechanism. Angewandte Chemie (International ed. in English) 61 (19) (2022)
Marlon Henrique Cardoso, Lai Yue Chan, Elizabete S Cândido, Danieli F Buccini, Samilla B Rezende, Marcelo Der Torossian Torres, Karen G N Oshiro, Ítala C Silva, Sónia Gonçalves, Timothy K Lu, Nuno C Santos, de la Fuente-Nunez Cesar, David J Craik, Octávio Luiz Franco
An N-capping asparagine-lysine-proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold. Chemical science 13 (32) (2022)
Yuhui Zhang, Li Wang, Benjamin J Tombling, Carmen Lammi, Yen-Hua Huang, Yue Li, Martina Bartolomei, Bin Hong, David J Craik, Conan K Wang
Improving Stability Enhances In Vivo Efficacy of a PCSK9 Inhibitory Peptide. Journal of the American Chemical Society 144 (42) (2022)
Yue Wu, Zhenling Cui, Yen-Hua Huang, Simon J de Veer, Mikhail S Baranov, Zhong Guo, Shayli V Moradi, Alexandra O Hinton, Jennifer R Deuis, Shaodong Guo, Kai-En Chen, Brett M Collins, Irina Vetter, Volker Herzig, Alun Jones, Matthew A Cooper, Glenn F King, David J Craik, Kirill Alexandrov, Sergey Mureev
Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system. Nature communications 13 (1) (2022)
Andrew M White, Anita Dellsén, Niklas Larsson, Quentin Kaas, Frank Jansen, Alleyn T Plowright, Laurent Knerr, Thomas Durek, David J Craik
Late-Stage Functionalization with Cysteine Staples Generates Potent and Selective Melanocortin Receptor-1 Agonists. Journal of medicinal chemistry 65 (19) (2022)
Mark A Jackson, Lai Yue Chan, Maxim D Harding, David J Craik, Edward K Gilding
Rational domestication of a plant-based recombinant expression system expands its biosynthetic range. Journal of experimental botany 73 (18) (2022)
Susana A Dias, Sandra N Pinto, Ana S Silva-Herdade, Olivier Cheneval, David J Craik, Ana Coutinho, Miguel A R B Castanho, Sónia T Henriques, Ana Salomé Veiga
A designed cyclic analogue of gomesin has potent activity against Staphylococcus aureus biofilms. The Journal of antimicrobial chemotherapy 77 (12) (2022)
Sixin Tian, Thomas Durek, Conan K Wang, Christina N Zdenek, Bryan G Fry, David J Craik, Simon J de Veer
Engineering the Cyclization Loop of MCoTI-II Generates Targeted Cyclotides that Potently Inhibit Factor XIIa. Journal of medicinal chemistry 65 (23) (2022)
Vivian Cody, Jia Q Truong, Bruce A Holdsworth, Jessica K Holien, Samantha J Richardson, David K Chalmers, David J Craik
Structural Analysis of the Complex of Human Transthyretin with 3',5'-Dichlorophenylanthranilic Acid at 1.5 Å Resolution. Molecules (Basel, Switzerland) 27 (21) (2022)
Hue N T Tran, Poanna Tran, Jennifer R Deuis, Kirsten L McMahon, Kuok Yap, David J Craik, Irina Vetter, Christina I Schroeder
Evaluation of Efficient Non-reducing Enzymatic and Chemical Ligation Strategies for Complex Disulfide-Rich Peptides. Bioconjugate chemistry 32 (11) (2021)
Benjamin J Tombling, Carmen Lammi, Carlotta Bollati, Anna Anoldi, David J Craik, Conan K Wang
Increased Valency Improves Inhibitory Activity of Peptides Targeting Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9). Chembiochem : a European journal of chemical biology 22 (12) (2021)
Anna S Amiss, Jessica B von Pein, Jessica R Webb, Nicholas D Condon, Peta J Harvey, Minh Duy Phan, Mark A Schembri, Bart J Currie, Matthew J Sweet, David J Craik, Ronan Kapetanovic, Sónia Troeira Henriques, Nicole Lawrence
Modified horseshoe crab peptides target and kill bacteria inside host cells. Cellular and molecular life sciences : CMLS 79 (1) (2021)
Arik J Hone, Quentin Kaas, Ireland Kearns, Fuaad Hararah, Joanna Gajewiak, Sean Christensen, David J Craik, J Michael McIntosh
Computational and Functional Mapping of Human and Rat α6β4 Nicotinic Acetylcholine Receptors Reveals Species-Specific Ligand-Binding Motifs. Journal of medicinal chemistry 64 (3) (2021)
Roland Hellinger, Edin Muratspahić, Seema Devi, Johannes Koehbach, Mina Vasileva, Peta J Harvey, David J Craik, Carsten Gründemann, Christian W Gruber
Importance of the Cyclic Cystine Knot Structural Motif for Immunosuppressive Effects of Cyclotides. ACS chemical biology 16 (11) (2021)
Tien T Dang, Lai Yue Chan, Benjamin J Tombling, Peta J Harvey, Edward K Gilding, David J Craik
In Planta Discovery and Chemical Synthesis of Bracelet Cystine Knot Peptides from Rinorea bengalensis. Journal of natural products 84 (2) (2021)
Grégoire Jean-Baptiste Philippe, Anna Mittermeier, Nicole Lawrence, Yen-Hua Huang, Nicholas D Condon, Alexander Loewer, David J Craik, Sónia Troeira Henriques
Angler Peptides: Macrocyclic Conjugates Inhibit p53:MDM2/X Interactions and Activate Apoptosis in Cancer Cells. ACS chemical biology 16 (2) (2021)
Huawu Yin, Yen-Hua Huang, Sarah A Best, Kate D Sutherland, David J Craik, Conan K Wang
An Integrated Molecular Grafting Approach for the Design of Keap1-Targeted Peptide Inhibitors. ACS chemical biology 16 (7) (2021)
Yen-Hua Huang, Qingdan Du, Zhihao Jiang, Gordon J King, Brett M Collins, Conan K Wang, David J Craik
Enabling Efficient Folding and High-Resolution Crystallographic Analysis of Bracelet Cyclotides. Molecules (Basel, Switzerland) 26 (18) (2021)
Thomas Durek, Quentin Kaas, Andrew M White, Joachim Weidmann, Abdullah Ahmad Fuaad, Olivier Cheneval, Christina I Schroeder, Simon J de Veer, Anita Dellsén, Torben Österlund, Niklas Larsson, Laurent Knerr, Udo Bauer, Alleyn T Plowright, David J Craik
Melanocortin 1 Receptor Agonists Based on a Bivalent, Bicyclic Peptide Framework. Journal of medicinal chemistry 64 (14) (2021)
Huawu Yin, Xiuman Zhou, Yen-Hua Huang, Gordon J King, Brett M Collins, Yanfeng Gao, David J Craik, Conan K Wang
Rational Design of Potent Peptide Inhibitors of the PD-1:PD-L1 Interaction for Cancer Immunotherapy. Journal of the American Chemical Society 143 (44) (2021)
Xiaosa Wu, David J Craik, Quentin Kaas
Interactions of Globular and Ribbon [γ4E]GID with α4β2 Neuronal Nicotinic Acetylcholine Receptor. Marine drugs 19 (9) (2021)
Benjamin J Tombling, Carmen Lammi, Nicole Lawrence, Jianqiang Li, Anna Arnoldi, David J Craik, Conan K Wang
Engineered EGF-A Peptides with Improved Affinity for Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9). ACS chemical biology 16 (2) (2021)
Wenyu Liu, Simon J de Veer, Yen-Hua Huang, Toru Sengoku, Chikako Okada, Kazuhiro Ogata, Christina N Zdenek, Bryan G Fry, Joakim E Swedberg, Toby Passioura, David J Craik, Hiroaki Suga
An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human β-Factor XIIa in a Cyclotide Scaffold. Journal of the American Chemical Society 143 (44) (2021)
Shuai Wang, Xiaopeng Zhu, Manqi Zhangsun, Yong Wu, Jinpeng Yu, Peta J Harvey, Quentin Kaas, Dongting Zhangsun, David J Craik, Sulan Luo
Engineered Conotoxin Differentially Blocks and Discriminates Rat and Human α7 Nicotinic Acetylcholine Receptors. Journal of medicinal chemistry 64 (9) (2021)
Ferran Nadal-Bufi, Jody M Mason, Lai Yue Chan, David J Craik, Quentin Kaas, Sónia Troeira Henriques
Designed β-Hairpins Inhibit LDH5 Oligomerization and Enzymatic Activity. Journal of medicinal chemistry 64 (7) (2021)
Anne-Sophie Depuydt, Jérôme Rihon, Olivier Cheneval, Michiel Vanmeert, Christina I Schroeder, David J Craik, Eveline Lescrinier, Steve Peigneur, Jan Tytgat
Cyclic Peptides as T-Type Calcium Channel Blockers: Characterization and Molecular Mapping of the Binding Site. ACS pharmacology & translational science 4 (4) (2021)
Kuok Yap, Junqiao Du, Fabian B H Rehm, Shyn Ric Tang, Yan Zhou, Jing Xie, Conan K Wang, Simon J de Veer, Linda H L Lua, Thomas Durek, David J Craik
Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases. Nature protocols 16 (3) (2021)
Edin Muratspahić, Nataša Tomašević, Johannes Koehbach, Leopold Duerrauer, Seid Hadžić, Joel Castro, Gudrun Schober, Spyridon Sideromenos, Richard J Clark, Stuart M Brierley, David J Craik, Christian W Gruber
Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain. Journal of medicinal chemistry 64 (13) (2021)
David J Craik, Meng-Wei Kan
How can we improve peptide drug discovery? Learning from the past. Expert opinion on drug discovery 16 (12) (2021)
Meri Emili F Pinto, Lai Yue Chan, Johannes Koehbach, Seema Devi, Carsten Gründemann, Christian W Gruber, Mario Gomes, Vanderlan da Silva Bolzani, Eduardo Maffud Cilli, David J Craik
Cyclotides from Brazilian Palicourea sessilis and Their Effects on Human Lymphocytes. Journal of natural products 84 (1) (2021)
Fabian B H Rehm, Tristan J Tyler, Kuok Yap, Simon J de Veer, David J Craik, Thomas Durek
Enzymatic C-Terminal Protein Engineering with Amines. Journal of the American Chemical Society 143 (46) (2021)
Johannes Koehbach, Jurnorain Gani, Kai Hilpert, David J Craik
Comparison of a Short Linear Antimicrobial Peptide with Its Disulfide-Cyclized and Cyclotide-Grafted Variants against Clinically Relevant Pathogens. Microorganisms 9 (6) (2021)
Lai Yue Chan, Junqiao Du, David J Craik
Tuning the Anti-Angiogenic Effect of the P15 Peptide Using Cyclic Trypsin Inhibitor Scaffolds. ACS chemical biology 16 (5) (2021)
Jessica A I Muller, Nicole Lawrence, Lai Yue Chan, Peta J Harvey, Alysha G Elliott, Mark A T Blaskovich, Jacqueline C Gonçalves, Priscilla Galante, Márcia Renata Mortari, Mônica C Toffoli-Kadri, Johannes Koehbach, David J Craik
Antimicrobial and Anticancer Properties of Synthetic Peptides Derived from the Wasp Parachartergus fraternus. Chembiochem : a European journal of chemical biology 22 (8) (2021)
Hayden Peacock, Sónia Troeira Henriques, Aurélie H Benfield, Alysha G Elliott, Jinghui Luo, James Luccarelli, Masanobu Nagano, David J Craik, Andrew D Hamilton
Antimicrobial Peptide Mimetics Based on a Diphenylacetylene Scaffold: Synthesis, Conformational Analysis, and Activity. ChemMedChem 15 (20) (2020)
Andrew M White, Simon J de Veer, Guojie Wu, Peta J Harvey, Kuok Yap, Gordon J King, Joakim E Swedberg, Conan K Wang, Ruby H P Law, Thomas Durek, David J Craik
Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides. Angewandte Chemie (International ed. in English) 59 (28) (2020)
Ida K Ø Hansen, Johan Isaksson, Aaron G Poth, Kine Østnes Hansen, Aaron John Christian Andersen, Céline S M Richard, Hans-Matti Blencke, Klara Stensvåg, David J Craik, Tor Haug
Isolation and Characterization of Antimicrobial Peptides with Unusual Disulfide Connectivity from the Colonial Ascidian Synoicum turgens. Marine drugs 18 (1) (2020)
Junqiao Du, Kuok Yap, Lai Yue Chan, Fabian B H Rehm, Fong Yang Looi, Aaron G Poth, Edward K Gilding, Quentin Kaas, Thomas Durek, David J Craik
A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors. Nature communications 11 (1) (2020)
Benjamin J Tombling, Carmen Lammi, Nicole Lawrence, Edward K Gilding, Giovanni Grazioso, David J Craik, Conan K Wang
Bioactive Cyclization Optimizes the Affinity of a Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Peptide Inhibitor. Journal of medicinal chemistry 64 (5) (2020)
Fabian B H Rehm, Tristan J Tyler, Kuok Yap, Thomas Durek, David J Craik
Improved Asparaginyl-Ligase-Catalyzed Transpeptidation via Selective Nucleophile Quenching. Angewandte Chemie (International ed. in English) 60 (8) (2020)

David J Craik.css-eqlu8i{font-size:small;padding-left:4px;} (David Craik, D J Craik)

Publication Activity (10 Years)

Top Topics

Top Venues

David J Craik (David Craik, D J Craik)