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David J Craik (David Craik, D J Craik)

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 126

Top Venues

Journal of medicinal chemistry

ACS chemical biology

Journal of natural products

Angewandte Chemie (International ed. in English)

This page only lists publications with an associated author ORCID identifier.

Publications

Edin Muratspahić, Kristine Deibler, Jianming Han, Nataša Tomašević, Kirtikumar B Jadhav, Aina-Leonor Olivé-Marti, Nadine Hochrainer, Roland Hellinger, Johannes Koehbach, Jonathan F Fay, Mohammad Homaidur Rahman, Lamees Hegazy, Timothy W Craven, Balazs R Varga, Gaurav Bhardwaj, Kevin Appourchaux, Susruta Majumdar, Markus Muttenthaler, Parisa Hosseinzadeh, David J Craik, Mariana Spetea, Tao Che, Julien S Baker, Christian W Gruber
Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor. Nature communications 14 (1) (2023)
Tristan J Tyler, Thomas Durek, David J Craik
Native and Engineered Cyclic Disulfide-Rich Peptides as Drug Leads. Molecules (Basel, Switzerland) 28 (7) (2023)
Pan Xu, Panpan Zhang, Xiaopeng Zhu, Yong Wu, Peta J Harvey, Quentin Kaas, Dongting Zhangsun, David J Craik, Sulan Luo
Structure-Activity Relationships of Alanine Scan Mutants αO-Conotoxins GeXIVA[1,2] and GeXIVA[1,4]. Journal of medicinal chemistry (2023)
Linh T T Nguyen, David J Craik, Quentin Kaas
Bibliometric Review of the Literature on Cone Snail Peptide Toxins from 2000 to 2022. Marine drugs 21 (3) (2023)
Linh T T Nguyen, David J Craik, Quentin Kaas
Bibliometric Review of the Literature on Cone Snail Peptide Toxins from 2000 to 2022. Marine drugs 21 (3) (2023)
Xiaopeng Zhu, Shuai Wang, Quentin Kaas, Jinpeng Yu, Yong Wu, Peta J Harvey, Dongting Zhangsun, David J Craik, Sulan Luo
Discovery, Characterization, and Engineering of LvIC, an α4/4-Conotoxin That Selectively Blocks Rat α6/α3β4 Nicotinic Acetylcholine Receptors. Journal of medicinal chemistry 66 (3) (2023)
Mark A Jackson, Jing Xie, Linh T T Nguyen, Xiaohan Wang, Kuok Yap, Peta J Harvey, Edward K Gilding, David J Craik
Plant-based production of an orally active cyclotide for the treatment of multiple sclerosis. Transgenic research (2023)
Zhian Chen, Yanfang Cui, Yin Yao, Bo Liu, Joseph Yunis, Xin Gao, Naiqi Wang, Pablo F Cañete, Zewen Kelvin Tuong, Hongjian Sun, Hao Wang, Si-Ling Yang, Runli Wang, Yew Ann Leong, David Simon Davis, Jiahuan Qin, Kaili Liang, Jun Deng, Conan K Wang, Yen-Hua Huang, Jonathan A Roco, Sam Nettelfield, Huaming Zhu, Huajun Xu, Zhijia Yu, David J Craik, Zheng Liu, Hai Qi, Christopher R Parish, Di Yu
Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology 8 (80) (2023)
Zhian Chen, Yanfang Cui, Yin Yao, Bo Liu, Joseph Yunis, Xin Gao, Naiqi Wang, Pablo F Cañete, Zewen Kelvin Tuong, Hongjian Sun, Hao Wang, Si-Ling Yang, Runli Wang, Yew Ann Leong, David Simon Davis, Jiahuan Qin, Kaili Liang, Jun Deng, Conan K Wang, Yen-Hua Huang, Jonathan A Roco, Sam Nettelfield, Huaming Zhu, Huajun Xu, Zhijia Yu, David J Craik, Zheng Liu, Hai Qi, Christopher R Parish, Di Yu
Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology 8 (80) (2023)
Xiaorong Liu, Sónia T Henriques, David J Craik, Lai Yue Chan
Unlocking the Potential of the Antimicrobial Peptide Gomesin: From Discovery and Structure-Activity Relationships to Therapeutic Applications. International journal of molecular sciences 24 (6) (2023)
Edin Muratspahić, Despoina Aslanoglou, Andrew M White, Claudia Draxler, Xaver Kozisek, Zara Farooq, David J Craik, Peter J McCormick, Thomas Durek, Christian W Gruber
Development of Melanocortin 4 Receptor Agonists by Exploiting Animal-Derived Macrocyclic, Disulfide-Rich Peptide Scaffolds. ACS pharmacology & translational science 6 (10) (2023)
Xiaopeng Zhu, Shuai Wang, Quentin Kaas, Jinpeng Yu, Yong Wu, Peta J Harvey, Dongting Zhangsun, David J Craik, Sulan Luo
Discovery, Characterization, and Engineering of LvIC, an α4/4-Conotoxin That Selectively Blocks Rat α6/α3β4 Nicotinic Acetylcholine Receptors. Journal of medicinal chemistry 66 (3) (2023)
Edin Muratspahić, Andrew M White, Cosmin I Ciotu, Nadine Hochrainer, Nataša Tomašević, Johannes Koehbach, Richard James Lewis, Mariana Spetea, Michael J M Fischer, David J Craik, Christian W Gruber
Development of a Selective Peptide κ-Opioid Receptor Antagonist by Late-Stage Functionalization with Cysteine Staples. Journal of medicinal chemistry (2023)
Xiaorong Liu, Sónia T Henriques, David J Craik, Lai Yue Chan
Unlocking the Potential of the Antimicrobial Peptide Gomesin: From Discovery and Structure-Activity Relationships to Therapeutic Applications. International journal of molecular sciences 24 (6) (2023)
Abhishek Bajpai, Mark A Jackson, Yen-Hua Huang, Kuok Yap, Qingdan Du, Tevin Chui-Ying Chau, David J Craik, Edward K Gilding
Nematicidal Activity of Cyclotides: Toxicity Against Caenorhabditis elegans . Journal of natural products (2023)
Linh T T Nguyen, David J Craik, Quentin Kaas
Bibliometric Review of the Literature on Cone Snail Peptide Toxins from 2000 to 2022. Marine drugs 21 (3) (2023)
Xiaopeng Zhu, Shuai Wang, Quentin Kaas, Jinpeng Yu, Yong Wu, Peta J Harvey, Dongting Zhangsun, David J Craik, Sulan Luo
Discovery, Characterization, and Engineering of LvIC, an α4/4-Conotoxin That Selectively Blocks Rat α6/α3β4 Nicotinic Acetylcholine Receptors. Journal of medicinal chemistry 66 (3) (2023)
Nicole L van der Weerden, Kathy Parisi, James A McKenna, Brigitte M Hayes, Peta J Harvey, Pedro Quimbar, Sean R Wevrett, Prem K Veneer, Owen McCorkelle, Shaily Vasa, Rosemary Guarino, Simon Poon, Yolanda M Gaspar, Michael J Baker, David J Craik, Rob B Turner, Marc B Brown, Mark R Bleackley, Marilyn A Anderson
The Plant Defensin Ppdef1 Is a Novel Topical Treatment for Onychomycosis. Journal of fungi (Basel, Switzerland) 9 (11) (2023)
Linh T T Nguyen, David J Craik, Quentin Kaas
Bibliometric Review of the Literature on Cone Snail Peptide Toxins from 2000 to 2022. Marine drugs 21 (3) (2023)
Xiaorong Liu, Sónia T Henriques, David J Craik, Lai Yue Chan
Unlocking the Potential of the Antimicrobial Peptide Gomesin: From Discovery and Structure-Activity Relationships to Therapeutic Applications. International journal of molecular sciences 24 (6) (2023)
Isabella R Palombi, Nicole Lawrence, Andrew M White, Caitlin L Gare, David J Craik, Brendan J McMorran, Lara R Malins
Development of Antiplasmodial Peptide-Drug Conjugates Using a Human Protein-Derived Cell-Penetrating Peptide with Selectivity for Infected Cells. Bioconjugate chemistry (2023)
Xiaopeng Zhu, Shuai Wang, Quentin Kaas, Jinpeng Yu, Yong Wu, Peta J Harvey, Dongting Zhangsun, David J Craik, Sulan Luo
Discovery, Characterization, and Engineering of LvIC, an α4/4-Conotoxin That Selectively Blocks Rat α6/α3β4 Nicotinic Acetylcholine Receptors. Journal of medicinal chemistry (2023)
Zhian Chen, Yanfang Cui, Yin Yao, Bo Liu, Joseph Yunis, Xin Gao, Naiqi Wang, Pablo F Cañete, Zewen Kelvin Tuong, Hongjian Sun, Hao Wang, Si-Ling Yang, Runli Wang, Yew Ann Leong, David Simon Davis, Jiahuan Qin, Kaili Liang, Jun Deng, Conan K Wang, Yen-Hua Huang, Jonathan A Roco, Sam Nettelfield, Huaming Zhu, Huajun Xu, Zhijia Yu, David J Craik, Zheng Liu, Hai Qi, Christopher R Parish, Di Yu
Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology 8 (80) (2023)
Zhian Chen, Yanfang Cui, Yin Yao, Bo Liu, Joseph Yunis, Xin Gao, Naiqi Wang, Pablo F Cañete, Zewen Kelvin Tuong, Hongjian Sun, Hao Wang, Si-Ling Yang, Runli Wang, Yew Ann Leong, David Simon Davis, Jiahuan Qin, Kaili Liang, Jun Deng, Conan K Wang, Yen-Hua Huang, Jonathan A Roco, Sam Nettelfield, Huaming Zhu, Huajun Xu, Zhijia Yu, David J Craik, Zheng Liu, Hai Qi, Christopher R Parish, Di Yu
Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology 8 (80) (2023)
Kirsten L McMahon, Hue N T Tran, Jennifer R Deuis, David J Craik, Irina Vetter, Christina I Schroeder
µ-Conotoxins Targeting the Human Voltage-Gated Sodium Channel Subtype Na V 1.7. Toxins 14 (9) (2022)
Fabian B H Rehm, Tristan J Tyler, Simon J de Veer, David J Craik, Thomas Durek
Enzymatic C-to-C Protein Ligation. Angewandte Chemie (International ed. in English) 61 (11) (2022)
Choi Yi Li, Fabian B H Rehm, Kuok Yap, Christina N Zdenek, Maxim D Harding, Bryan G Fry, Thomas Durek, David J Craik, Simon J de Veer
Cystine Knot Peptides with Tuneable Activity and Mechanism. Angewandte Chemie (International ed. in English) 61 (19) (2022)
Marlon Henrique Cardoso, Lai Yue Chan, Elizabete S Cândido, Danieli F Buccini, Samilla B Rezende, Marcelo Der Torossian Torres, Karen G N Oshiro, Ítala C Silva, Sónia Gonçalves, Timothy K Lu, Nuno C Santos, de la Fuente-Nunez Cesar, David J Craik, Octávio Luiz Franco
An N-capping asparagine-lysine-proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold. Chemical science 13 (32) (2022)
Yuhui Zhang, Li Wang, Benjamin J Tombling, Carmen Lammi, Yen-Hua Huang, Yue Li, Martina Bartolomei, Bin Hong, David J Craik, Conan K Wang
Improving Stability Enhances In Vivo Efficacy of a PCSK9 Inhibitory Peptide. Journal of the American Chemical Society 144 (42) (2022)
Yue Wu, Zhenling Cui, Yen-Hua Huang, Simon J de Veer, Mikhail S Baranov, Zhong Guo, Shayli V Moradi, Alexandra O Hinton, Jennifer R Deuis, Shaodong Guo, Kai-En Chen, Brett M Collins, Irina Vetter, Volker Herzig, Alun Jones, Matthew A Cooper, Glenn F King, David J Craik, Kirill Alexandrov, Sergey Mureev
Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system. Nature communications 13 (1) (2022)
Andrew M White, Anita Dellsén, Niklas Larsson, Quentin Kaas, Frank Jansen, Alleyn T Plowright, Laurent Knerr, Thomas Durek, David J Craik
Late-Stage Functionalization with Cysteine Staples Generates Potent and Selective Melanocortin Receptor-1 Agonists. Journal of medicinal chemistry 65 (19) (2022)
Mark A Jackson, Lai Yue Chan, Maxim D Harding, David J Craik, Edward K Gilding
Rational domestication of a plant-based recombinant expression system expands its biosynthetic range. Journal of experimental botany 73 (18) (2022)
Susana A Dias, Sandra N Pinto, Ana S Silva-Herdade, Olivier Cheneval, David J Craik, Ana Coutinho, Miguel A R B Castanho, Sónia T Henriques, Ana Salomé Veiga
A designed cyclic analogue of gomesin has potent activity against Staphylococcus aureus biofilms. The Journal of antimicrobial chemotherapy 77 (12) (2022)
Sixin Tian, Thomas Durek, Conan K Wang, Christina N Zdenek, Bryan G Fry, David J Craik, Simon J de Veer
Engineering the Cyclization Loop of MCoTI-II Generates Targeted Cyclotides that Potently Inhibit Factor XIIa. Journal of medicinal chemistry 65 (23) (2022)
Vivian Cody, Jia Q Truong, Bruce A Holdsworth, Jessica K Holien, Samantha J Richardson, David K Chalmers, David J Craik
Structural Analysis of the Complex of Human Transthyretin with 3',5'-Dichlorophenylanthranilic Acid at 1.5 Å Resolution. Molecules (Basel, Switzerland) 27 (21) (2022)
Hue N T Tran, Poanna Tran, Jennifer R Deuis, Kirsten L McMahon, Kuok Yap, David J Craik, Irina Vetter, Christina I Schroeder
Evaluation of Efficient Non-reducing Enzymatic and Chemical Ligation Strategies for Complex Disulfide-Rich Peptides. Bioconjugate chemistry 32 (11) (2021)
Benjamin J Tombling, Carmen Lammi, Carlotta Bollati, Anna Anoldi, David J Craik, Conan K Wang
Increased Valency Improves Inhibitory Activity of Peptides Targeting Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9). Chembiochem : a European journal of chemical biology 22 (12) (2021)
Anna S Amiss, Jessica B von Pein, Jessica R Webb, Nicholas D Condon, Peta J Harvey, Minh Duy Phan, Mark A Schembri, Bart J Currie, Matthew J Sweet, David J Craik, Ronan Kapetanovic, Sónia Troeira Henriques, Nicole Lawrence
Modified horseshoe crab peptides target and kill bacteria inside host cells. Cellular and molecular life sciences : CMLS 79 (1) (2021)
Arik J Hone, Quentin Kaas, Ireland Kearns, Fuaad Hararah, Joanna Gajewiak, Sean Christensen, David J Craik, J Michael McIntosh
Computational and Functional Mapping of Human and Rat α6β4 Nicotinic Acetylcholine Receptors Reveals Species-Specific Ligand-Binding Motifs. Journal of medicinal chemistry 64 (3) (2021)
Roland Hellinger, Edin Muratspahić, Seema Devi, Johannes Koehbach, Mina Vasileva, Peta J Harvey, David J Craik, Carsten Gründemann, Christian W Gruber
Importance of the Cyclic Cystine Knot Structural Motif for Immunosuppressive Effects of Cyclotides. ACS chemical biology 16 (11) (2021)
Tien T Dang, Lai Yue Chan, Benjamin J Tombling, Peta J Harvey, Edward K Gilding, David J Craik
In Planta Discovery and Chemical Synthesis of Bracelet Cystine Knot Peptides from Rinorea bengalensis. Journal of natural products 84 (2) (2021)
Grégoire J-B Philippe, Anna Mittermeier, Nicole Lawrence, Yen-Hua Huang, Nicholas D Condon, Alexander Loewer, David J Craik, Sónia Troeira Henriques
Angler Peptides: Macrocyclic Conjugates Inhibit p53:MDM2/X Interactions and Activate Apoptosis in Cancer Cells. ACS chemical biology 16 (2) (2021)
Huawu Yin, Yen-Hua Huang, Sarah A Best, Kate D Sutherland, David J Craik, Conan K Wang
An Integrated Molecular Grafting Approach for the Design of Keap1-Targeted Peptide Inhibitors. ACS chemical biology 16 (7) (2021)
Yen-Hua Huang, Qingdan Du, Zhihao Jiang, Gordon J King, Brett M Collins, Conan K Wang, David J Craik
Enabling Efficient Folding and High-Resolution Crystallographic Analysis of Bracelet Cyclotides. Molecules (Basel, Switzerland) 26 (18) (2021)
Thomas Durek, Quentin Kaas, Andrew M White, Joachim Weidmann, Abdullah Ahmad Fuaad, Olivier Cheneval, Christina I Schroeder, Simon J de Veer, Anita Dellsén, Torben Österlund, Niklas Larsson, Laurent Knerr, Udo Bauer, Alleyn T Plowright, David J Craik
Melanocortin 1 Receptor Agonists Based on a Bivalent, Bicyclic Peptide Framework. Journal of medicinal chemistry 64 (14) (2021)
Huawu Yin, Xiuman Zhou, Yen-Hua Huang, Gordon J King, Brett M Collins, Yanfeng Gao, David J Craik, Conan K Wang
Rational Design of Potent Peptide Inhibitors of the PD-1:PD-L1 Interaction for Cancer Immunotherapy. Journal of the American Chemical Society 143 (44) (2021)
Xiaosa Wu, David J Craik, Quentin Kaas
Interactions of Globular and Ribbon [γ4E]GID with α4β2 Neuronal Nicotinic Acetylcholine Receptor. Marine drugs 19 (9) (2021)
Benjamin J Tombling, Carmen Lammi, Nicole Lawrence, Jianqiang Li, Anna Arnoldi, David J Craik, Conan K Wang
Engineered EGF-A Peptides with Improved Affinity for Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9). ACS chemical biology 16 (2) (2021)
Wenyu Liu, Simon J de Veer, Yen-Hua Huang, Toru Sengoku, Chikako Okada, Kazuhiro Ogata, Christina N Zdenek, Bryan G Fry, Joakim E Swedberg, Toby Passioura, David J Craik, Hiroaki Suga
An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human β-Factor XIIa in a Cyclotide Scaffold. Journal of the American Chemical Society 143 (44) (2021)
Shuai Wang, Xiaopeng Zhu, Manqi Zhangsun, Yong Wu, Jinpeng Yu, Peta J Harvey, Quentin Kaas, Dongting Zhangsun, David J Craik, Sulan Luo
Engineered Conotoxin Differentially Blocks and Discriminates Rat and Human α7 Nicotinic Acetylcholine Receptors. Journal of medicinal chemistry 64 (9) (2021)
Ferran Nadal-Bufi, Jody M Mason, Lai Yue Chan, David J Craik, Quentin Kaas, Sónia Troeira Henriques
Designed β-Hairpins Inhibit LDH5 Oligomerization and Enzymatic Activity. Journal of medicinal chemistry 64 (7) (2021)
Anne-Sophie Depuydt, Jérôme Rihon, Olivier Cheneval, Michiel Vanmeert, Christina I Schroeder, David J Craik, Eveline Lescrinier, Steve Peigneur, Jan Tytgat
Cyclic Peptides as T-Type Calcium Channel Blockers: Characterization and Molecular Mapping of the Binding Site. ACS pharmacology & translational science 4 (4) (2021)
Kuok Yap, Junqiao Du, Fabian B H Rehm, Shyn Ric Tang, Yan Zhou, Jing Xie, Conan K Wang, Simon J de Veer, Linda H L Lua, Thomas Durek, David J Craik
Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases. Nature protocols 16 (3) (2021)
Edin Muratspahić, Nataša Tomašević, Johannes Koehbach, Leopold Duerrauer, Seid Hadžić, Joel Castro, Gudrun Schober, Spyridon Sideromenos, Richard J Clark, Stuart M Brierley, David J Craik, Christian W Gruber
Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain. Journal of medicinal chemistry 64 (13) (2021)
David J Craik, Meng-Wei Kan
How can we improve peptide drug discovery? Learning from the past. Expert opinion on drug discovery 16 (12) (2021)
Meri Emili F Pinto, Lai Yue Chan, Johannes Koehbach, Seema Devi, Carsten Gründemann, Christian W Gruber, Mario Gomes, Vanderlan da Silva Bolzani, Eduardo Maffud Cilli, David J Craik
Cyclotides from Brazilian Palicourea sessilis and Their Effects on Human Lymphocytes. Journal of natural products 84 (1) (2021)
Fabian B H Rehm, Tristan J Tyler, Kuok Yap, Simon J de Veer, David J Craik, Thomas Durek
Enzymatic C-Terminal Protein Engineering with Amines. Journal of the American Chemical Society 143 (46) (2021)
Johannes Koehbach, Jurnorain Gani, Kai Hilpert, David J Craik
Comparison of a Short Linear Antimicrobial Peptide with Its Disulfide-Cyclized and Cyclotide-Grafted Variants against Clinically Relevant Pathogens. Microorganisms 9 (6) (2021)
Lai Yue Chan, Junqiao Du, David J Craik
Tuning the Anti-Angiogenic Effect of the P15 Peptide Using Cyclic Trypsin Inhibitor Scaffolds. ACS chemical biology 16 (5) (2021)
Jessica A I Muller, Nicole Lawrence, Lai Yue Chan, Peta J Harvey, Alysha G Elliott, Mark A T Blaskovich, Jacqueline C Gonçalves, Priscilla Galante, Márcia Renata Mortari, Mônica C Toffoli-Kadri, Johannes Koehbach, David J Craik
Antimicrobial and Anticancer Properties of Synthetic Peptides Derived from the Wasp Parachartergus fraternus. Chembiochem : a European journal of chemical biology 22 (8) (2021)
Hayden Peacock, Sónia Troeira Henriques, Aurélie H Benfield, Alysha G Elliott, Jinghui Luo, James Luccarelli, Masanobu Nagano, David J Craik, Andrew D Hamilton
Antimicrobial Peptide Mimetics Based on a Diphenylacetylene Scaffold: Synthesis, Conformational Analysis, and Activity. ChemMedChem 15 (20) (2020)
Andrew M White, Simon J de Veer, Guojie Wu, Peta J Harvey, Kuok Yap, Gordon J King, Joakim E Swedberg, Conan K Wang, Ruby H P Law, Thomas Durek, David J Craik
Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides. Angewandte Chemie (International ed. in English) 59 (28) (2020)
Ida K Ø Hansen, Johan Isaksson, Aaron G Poth, Kine Østnes Hansen, Aaron John Christian Andersen, Céline S M Richard, Hans-Matti Blencke, Klara Stensvåg, David J Craik, Tor Haug
Isolation and Characterization of Antimicrobial Peptides with Unusual Disulfide Connectivity from the Colonial Ascidian Synoicum turgens. Marine drugs 18 (1) (2020)
Junqiao Du, Kuok Yap, Lai Yue Chan, Fabian B H Rehm, Fong Yang Looi, Aaron G Poth, Edward K Gilding, Quentin Kaas, Thomas Durek, David J Craik
A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors. Nature communications 11 (1) (2020)
Benjamin J Tombling, Carmen Lammi, Nicole Lawrence, Edward K Gilding, Giovanni Grazioso, David J Craik, Conan K Wang
Bioactive Cyclization Optimizes the Affinity of a Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Peptide Inhibitor. Journal of medicinal chemistry 64 (5) (2020)
Fabian B H Rehm, Tristan J Tyler, Kuok Yap, Thomas Durek, David J Craik
Improved Asparaginyl-Ligase-Catalyzed Transpeptidation via Selective Nucleophile Quenching. Angewandte Chemie (International ed. in English) 60 (8) (2020)
Thomas N G Handley, Conan K Wang, Peta J Harvey, Nicole Lawrence, David J Craik
Cyclotide Structures Revealed by NMR, with a Little Help from X-ray Crystallography. Chembiochem : a European journal of chemical biology 21 (24) (2020)
Mathilde R Israel, Thomas S Dash, Stefanie N Bothe, Samuel D Robinson, Jennifer R Deuis, David J Craik, Angelika Lampert, Irina Vetter, Thomas Durek
Characterization of Synthetic Tf2 as a NaV1.3 Selective Pharmacological Probe. Biomedicines 8 (6) (2020)
Choi Yi Li, Kuok Yap, Joakim E Swedberg, David J Craik, Simon J de Veer
Binding Loop Substitutions in the Cyclic Peptide SFTI-1 Generate Potent and Selective Chymase Inhibitors. Journal of medicinal chemistry 63 (2) (2020)
Nicole Lawrence, Grégoire J-B Philippe, Peta J Harvey, Nicholas D Condon, Aurélie H Benfield, Olivier Cheneval, David J Craik, Sónia Troeira Henriques
Cyclic peptide scaffold with ability to stabilize and deliver a helical cell-impermeable cargo across membranes of cultured cancer cells. RSC chemical biology 1 (5) (2020)
Bronwyn J Smithies, Yen-Hua Huang, Mark A Jackson, Kuok Yap, Edward K Gilding, Karen S Harris, Marilyn A Anderson, David J Craik
Circular Permutation of the Native Enzyme-Mediated Cyclization Position in Cyclotides. ACS chemical biology 15 (4) (2020)
Benjamin J Tombling, Conan K Wang, David J Craik
EGF-like and Other Disulfide-rich Microdomains as Therapeutic Scaffolds. Angewandte Chemie (International ed. in English) 59 (28) (2020)
Edward K Gilding, Sina Jami, Jennifer R Deuis, Mathilde R Israel, Peta J Harvey, Aaron G Poth, Fabian B H Rehm, Jennifer L Stow, Samuel D Robinson, Kuok Yap, Darren L Brown, Brett R Hamilton, David A Andersson, David J Craik, Irina Vetter, Thomas Durek
Neurotoxic peptides from the venom of the giant Australian stinging tree. Science advances 6 (38) (2020)
Pan Xu, Quentin Kaas, Yong Wu, Xiaopeng Zhu, Xincan Li, Peta J Harvey, Dongting Zhangsun, David J Craik, Sulan Luo
Structure and Activity Studies of Disulfide-Deficient Analogues of αO-Conotoxin GeXIVA. Journal of medicinal chemistry 63 (4) (2020)
Akello Joanna Agwa, Poanna Tran, Alexander Mueller, Hue N T Tran, Jennifer R Deuis, Mathilde R Israel, Kirsten L McMahon, David J Craik, Irina Vetter, Christina I Schroeder
Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7. The Journal of biological chemistry 295 (15) (2020)
Edin Muratspahić, Johannes Koehbach, Christian W Gruber, David J Craik
Harnessing cyclotides to design and develop novel peptide GPCR ligands. RSC chemical biology 1 (4) (2020)
Tien T Dang, Lai Yue Chan, Yen-Hua Huang, Linh T T Nguyen, Quentin Kaas, Tien T Huynh, David J Craik
Exploring the Sequence Diversity of Cyclotides from Vietnamese Viola Species. Journal of natural products 83 (6) (2020)
Ashlin H Turner, Quentin Kaas, David J Craik
Hormone-like conopeptides - new tools for pharmaceutical design. RSC medicinal chemistry 11 (11) (2020)
Simon J de Veer, Andrew M White, David J Craik
Sunflower Trypsin Inhibitor-1 (SFTI-1): Sowing Seeds in the Fields of Chemistry and Biology. Angewandte Chemie (International ed. in English) 60 (15) (2020)
Qingdan Du, Yen-Hua Huang, Abhishek Bajpai, Majbrit Frosig-Jorgensen, Guangzu Zhao, David J Craik
Evaluation of the in Vivo Aphrodisiac Activity of a Cyclotide Extract from Hybanthus enneaspermus. Journal of natural products 83 (12) (2020)
Ri-Lei Yu, Jiayi Wang, Lok-Yan So, Peta J Harvey, Juan Shi, Jiazhen Liang, Qin Dou, Xiao Li, Xiayi Yan, Yen-Hua Huang, Qingliang Xu, Quentin Kaas, Ho-Yin Chow, Kwok-Yin Wong, David J Craik, Xiao-Hua Zhang, Tao Jiang, Yan Wang
Enhanced Activity against Multidrug-Resistant Bacteria through Coapplication of an Analogue of Tachyplesin I and an Inhibitor of the QseC/B Signaling Pathway. Journal of medicinal chemistry 63 (7) (2020)
Haiou Qu, Mark A Jackson, Kuok Yap, Peta J Harvey, Edward K Gilding, David J Craik
Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme. Planta 252 (6) (2020)
Huawu Yin, Yen-Hua Huang, Kirsten Deprey, Nicholas D Condon, Joshua A Kritzer, David J Craik, Conan K Wang
Cellular Uptake and Cytosolic Delivery of a Cyclic Cystine Knot Scaffold. ACS chemical biology 15 (6) (2020)
Qingdan Du, Lai Yue Chan, Edward K Gilding, Sónia Troeira Henriques, Nicholas D Condon, Anjaneya S Ravipati, Quentin Kaas, Yen-Hua Huang, David J Craik
Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus. The Journal of biological chemistry 295 (32) (2020)
Karen G N Oshiro, Elizabete de Souza Cândido, Lai Yue Chan, Marcelo D T Torres, Bruna E D Monges, Silvia G Rodrigues, William F Porto, Suzana M Ribeiro, Sónia Troeira Henriques, Timothy K Lu, de la Fuente-Nunez Cesar, David J Craik, Octávio Luiz Franco, Marlon Henrique Cardoso
Computer-Aided Design of Mastoparan-like Peptides Enables the Generation of Nontoxic Variants with Extended Antibacterial Properties. Journal of medicinal chemistry 62 (17) (2019)
Simon J de Veer, Meng-Wei Kan, David J Craik
Cyclotides: From Structure to Function. Chemical reviews 119 (24) (2019)
Felicitas Vernen, Peta J Harvey, Susana A Dias, Ana Salomé Veiga, Yen-Hua Huang, David J Craik, Nicole Lawrence, Sónia Troeira Henriques
Characterization of Tachyplesin Peptides and Their Cyclized Analogues to Improve Antimicrobial and Anticancer Properties. International journal of molecular sciences 20 (17) (2019)
Karen S Harris, Rosemary F Guarino, Ravindu S Dissanayake, Pedro Quimbar, Owen C McCorkelle, Simon Poon, Quentin Kaas, Thomas Durek, Edward K Gilding, Mark A Jackson, David J Craik, Nicole L van der Weerden, Robin F Anders, Marilyn A Anderson
A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein. Scientific reports 9 (1) (2019)
Fabian B H Rehm, Mark A Jackson, Ewout De Geyter, Kuok Yap, Edward K Gilding, Thomas Durek, David J Craik
Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization. Proceedings of the National Academy of Sciences of the United States of America 116 (16) (2019)
Grégoire J-B Philippe, Diana Gaspar, Caibin Sheng, Yen-Hua Huang, Aurélie H Benfield, Nicholas D Condon, Joachim Weidmann, Nicole Lawrence, Alexander Löwer, Miguel A R B Castanho, David J Craik, Sónia Troeira Henriques
Cell Membrane Composition Drives Selectivity and Toxicity of Designed Cyclic Helix-Loop-Helix Peptides with Cell Penetrating and Tumor Suppressor Properties. ACS chemical biology 14 (9) (2019)
Fabian B H Rehm, Thibault J Harmand, Kuok Yap, Thomas Durek, David J Craik, Hidde L Ploegh
Site-Specific Sequential Protein Labeling Catalyzed by a Single Recombinant Ligase. Journal of the American Chemical Society 141 (43) (2019)
Junqiao Du, Lai Yue Chan, Aaron G Poth, David J Craik
Discovery and Characterization of Cyclic and Acyclic Trypsin Inhibitors from Momordica dioica. Journal of natural products 82 (2) (2019)
Huawu Yin, David J Craik, Conan K Wang
Anchor Residues Guide Form and Function in Grafted Peptides. Angewandte Chemie (International ed. in English) 58 (23) (2019)
Sónia Troeira Henriques, Hayden Peacock, Aurélie H Benfield, Conan K Wang, David J Craik
Is the Mirror Image a True Reflection? Intrinsic Membrane Chirality Modulates Peptide Binding. Journal of the American Chemical Society 141 (51) (2019)
Ri-Lei Yu, Han-Shen Tae, Qingliang Xu, David J Craik, David J Adams, Tao Jiang, Quentin Kaas
Molecular dynamics simulations of dihydro-β-erythroidine bound to the human α4β2 nicotinic acetylcholine receptor. British journal of pharmacology 176 (15) (2019)
Elizabete S Cândido, Marlon Henrique Cardoso, Lai Yue Chan, Marcelo D T Torres, Karen G N Oshiro, William F Porto, Suzana M Ribeiro, Evan F Haney, Robert E W Hancock, Timothy K Lu, de la Fuente-Nunez Cesar, David J Craik, Octávio Luiz Franco
Short Cationic Peptide Derived from Archaea with Dual Antibacterial Properties and Anti-Infective Potential. ACS infectious diseases 5 (7) (2019)
Ai-Hua Jin, Markus Muttenthaler, Sebastien Dutertre, S W A Himaya, Quentin Kaas, David J Craik, Richard J Lewis, Paul F Alewood
Conotoxins: Chemistry and Biology. Chemical reviews 119 (21) (2019)
Conan K Wang, David J Craik
Toward Structure Determination of Disulfide-Rich Peptides Using Chemical Shift-Based Methods. The journal of physical chemistry. B 123 (9) (2019)
Choi Yi Li, Simon J de Veer, Andrew M White, Xingchen Chen, Jonathan M Harris, Joakim E Swedberg, David J Craik
Amino Acid Scanning at P5' within the Bowman-Birk Inhibitory Loop Reveals Specificity Trends for Diverse Serine Proteases. Journal of medicinal chemistry 62 (7) (2019)
Felicitas Vernen, David J Craik, Nicole Lawrence, Sónia Troeira Henriques
Cyclic Analogues of Horseshoe Crab Peptide Tachyplesin I with Anticancer and Cell Penetrating Properties. ACS chemical biology 14 (12) (2019)

David J Craik.css-eqlu8i{font-size:small;padding-left:4px;} (David Craik, D J Craik)

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David J Craik (David Craik, D J Craik)