Adrian J Thrasher (A J Thrasher)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 18

Top Topics

Acute Myeloid Leukemia

Endoplasmic Reticulum Stress

Top Venues

Human gene therapy

Nature medicine

European journal of immunology

The Journal of experimental medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Rajeev Rai, Zohar Steinberg, Marianna Romito, Federica Zinghirino, Yi-Ting Hu, Nathan White, Asma Naseem, Adrian J Thrasher, Giandomenico Turchiano, Alessia Cavazza
CRISPR/Cas9-Based Disease Modeling and Functional Correction of Interleukin 7 Receptor Alpha Severe Combined Immunodeficiency in T-Lymphocytes and Hematopoietic Stem Cells. Human gene therapy 35 (7-8) (2024)
Teng-Cheong Ha, Michael A Morgan, Adrian J Thrasher, Axel Schambach
Alpharetroviral Vector-Mediated Gene Therapy for IL7RA-Deficient Severe Combined Immunodeficiency. Human gene therapy (2024)
Rajeev Rai, Zohar Steinberg, Marianna Romito, Federica Zinghirino, Yi-Ting Hu, Nathan White, Asma Naseem, Adrian J Thrasher, Giandomenico Turchiano, Alessia Cavazza
CRISPR/Cas9-Based Disease Modeling and Functional Correction of Interleukin 7 Receptor Alpha Severe Combined Immunodeficiency in T-Lymphocytes and Hematopoietic Stem Cells. Human gene therapy (2024)
Rajeev Rai, Zohar Steinberg, Marianna Romito, Federica Zinghirino, Yi-Ting Hu, Nathan White, Asma Naseem, Adrian J Thrasher, Giandomenico Turchiano, Alessia Cavazza
CRISPR/Cas9-Based Disease Modeling and Functional Correction of Interleukin 7 Receptor Alpha Severe Combined Immunodeficiency in T-Lymphocytes and Hematopoietic Stem Cells. Human gene therapy 35 (7-8) (2024)
A Magnani, M Semeraro, Frédéric Adam, C Booth, L Dupré, Emma Catherine Morris, A Gabrion, C Roudaut, D Borgel, Antoine Toubert, Emmanuel Clave, C Abdo, G Gorochov, R Petermann, M Guiot, M Miyara, D Moshous, E Magrin, A Denis, F Suarez, Chantal Lagresle-Peyrou, A M Roche, J Everett, A Trinquand, M Guisset, J Xu Bayford, S Hacein-Bey-Abina, Alexandre Kauskot, R Elfeky, C Rivat, S Abbas, H B Gaspar, Elizabeth A Macintyre, C Picard, Frederic D Bushman, A Galy, Alain Fischer, Emmanuelle Six, Adrian J Thrasher, Marina Cavazzana
Long-term safety and efficacy of lentiviral hematopoietic stem/progenitor cell gene therapy for Wiskott-Aldrich syndrome. Nature medicine 28 (1) (2022)
William Rae, John M Sowerby, Dorit Verhoeven, Mariam M Youssef, Prasanti Kotagiri, Natalia Savinykh, Eve L Coomber, Alexis Boneparth, Angela Chan, Chun Gong, Machiel H Jansen, Romy du Long, Giorgia Santilli, Ilenia Simeoni, Jonathan Stephens, Kejia Wu, Marta Zinicola, Hana Lango Allen, Helen Baxendale, Dinakantha Kumararatne, Effrossyni Gkrania-Klotsas, Selma Cecilia Scheffler-Mendoza, Marco Antonio Yamazaki-Nakashimada, Laura Berrón Ruiz, Cesar Mauricio Rojas-Maruri, Saul Oswaldo Lugo-Reyes, Paul A Lyons, Anthony P Williams, Daniel James Hodson, Gail A Bishop, Adrian J Thrasher, David C Thomas, Michael P Murphy, Timothy J Vyse, Joshua D Milner, Taco W Kuijpers, Kenneth G C Smith
Immunodeficiency, autoimmunity, and increased risk of B cell malignancy in humans with TRAF3 mutations. Science immunology 7 (74) (2022)
Adrian Westhaus, Marti Cabanes-Creus, Timo Jonker, Erwan Sallard, Renina Gale Navarro, Erhua Zhu, Grober Baltazar Torres, Scott Lee, Patrick Wilmott, Anai Gonzalez-Cordero, Giorgia Santilli, Adrian J Thrasher, Ian E Alexander, Leszek Lisowski
AAV-p40 Bioengineering Platform for Variant Selection Based on Transgene Expression. Human gene therapy 33 (11-12) (2022)
Natalia Izotova, Christine Rivat, Cristina Baricordi, Elena Blanco, Danilo Pellin, Eleanor Watt, Athina S Gkazi, Stuart Paul Adams, Kimberley C Gilmour, Jinhua Bayford, Claire Booth, H Bobby Gaspar, Adrian J Thrasher, Luca Biasco
Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans. Nature communications 12 (1) (2021)
Elizabeth Rivers, Ying Hong, Mona Bajaj-Elliott, Austen Worth, Adrian J Thrasher
IL-18: A potential inflammation biomarker in Wiskott-Aldrich syndrome. European journal of immunology 51 (5) (2021)
Marti Cabanes-Creus, Claus V Hallwirth, Adrian Westhaus, Boaz H Ng, Sophia H Y Liao, Erhua Zhu, Renina Gale Navarro, Grober Baltazar, Matthieu Drouyer, Suzanne Scott, Grant J Logan, Giorgia Santilli, Antonette Bennett, Samantha L Ginn, Geoff William McCaughan, Adrian J Thrasher, Mavis Agbandje-McKenna, Ian E Alexander, Leszek Lisowski
Restoring the natural tropism of AAV2 vectors for human liver. Science translational medicine 12 (560) (2021)
Donald B Kohn, Claire Booth, Elizabeth M Kang, Sung-Yun Pai, Kit L Shaw, Giorgia Santilli, Myriam Armant, Karen F Buckland, Uimook Choi, Suk See De Ravin, Morna J Dorsey, Caroline Y Kuo, Diego Leon-Rico, Christine Rivat, Natalia Izotova, Kimberly Gilmour, Katie Snell, Jinhua Xu-Bayford Dip, Jinan Darwish, Emma Catherine Morris, Dayna Terrazas, Leo D Wang, Christopher A Bauser, Tobias Paprotka, Douglas B Kuhns, John Gregg, Hayley E Raymond, John K Everett, Geraldine Honnet, Luca Biasco, Peter E Newburger, Frederic D Bushman, Manuel Grez, H Bobby Gaspar, David A Williams, Harry L Malech, Anne Galy, Adrian J Thrasher, null null
Lentiviral gene therapy for X-linked chronic granulomatous disease. Nature medicine 26 (2) (2020)
Elizabeth Rivers, Rajeev Rai, Jonas Lötscher, Michael Hollinshead, Gasper Markelj, James Thaventhiran, Austen J Worth, Alessia Cavazza, Christoph Hess, Mona Bajaj-Elliott, Adrian J Thrasher
Wiskott Aldrich syndrome protein regulates non-selective autophagy and mitochondrial homeostasis in human myeloid cells. eLife 9 (2020)
James E D Thaventhiran, Hana Lango Allen, Oliver S Burren, William Rae, Daniel Greene, Emily Staples, Zinan Zhang, James H R Farmery, Ilenia Simeoni, Elizabeth Rivers, Jesmeen Maimaris, Christopher J Penkett, Jonathan Stephens, Sri V V Deevi, Alba Sanchis-Juan, Nicholas S Gleadall, Moira J Thomas, Ravishankar B Sargur, Pavels Gordins, Helen E Baxendale, Matthew Brown, Paul Tuijnenburg, Austen Worth, Steven Hanson, Rachel J Linger, Matthew S Buckland, Paula J Rayner-Matthews, Kimberly C Gilmour, Crina Samarghitean, Suranjith L Seneviratne, David M Sansom, Andrew G Lynch, Karine Megy, Eva Ellinghaus, David Ellinghaus, Silje F Jorgensen, Tom H Karlsen, Kathleen E Stirrups, Antony J Cutler, Dinakantha S Kumararatne, Anita Chandra, J David M Edgar, Archana Herwadkar, Nichola Cooper, Sofia Grigoriadou, Aarnoud P Huissoon, Sarah Goddard, Stephen Jolles, Catharina Schuetz, Felix Boschann, null null, Paul A Lyons, Matthew E Hurles, Sinisa Savic, Siobhan O Burns, Taco W Kuijpers, Ernest Turro, Willem Hendrik Ouwehand, Adrian J Thrasher, Kenneth G C Smith
Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature 583 (7814) (2020)
Rajeev Rai, Marianna Romito, Elizabeth Rivers, Giandomenico Turchiano, Georges Blattner, Winston Vetharoy, Dariusz Ladon, Geoffroy Andrieux, Fang Zhang, Marta Zinicola, Diego Leon-Rico, Giorgia Santilli, Adrian J Thrasher, Alessia Cavazza
Targeted gene correction of human hematopoietic stem cells for the treatment of Wiskott - Aldrich Syndrome. Nature communications 11 (1) (2020)
Sarah Spencer, Sevgi Köstel Bal, William Egner, Hana Lango Allen, Syed I Raza, Chi A Ma, Meltem Gürel, Yuan Zhang, Guangping Sun, Ruth A Sabroe, Daniel Greene, William Rae, Tala Shahin, Katarzyna Kania, Rico Chandra Ardy, Marini Thian, Emily Staples, Annika Pecchia-Bekkum, William P M Worrall, Jonathan Stephens, Matthew Brown, Salih Tuna, Melanie York, Fiona Shackley, Diarmuid Kerrin, Ravishankar B Sargur, Alison M Condliffe, Hamid Nawaz Tipu, Hye Sun Kuehn, Sergio D Rosenzweig, Ernest Turro, Simon Tavare, Adrian J Thrasher, Duncan Ian Jodrell, Kenneth G C Smith, Kaan Boztug, Joshua D Milner, James E D Thaventhiran
Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses. The Journal of experimental medicine 216 (9) (2019)
Alexandra Y Kreins, Florence Junghanns, William Mifsud, Kathy Somana, Neil J Sebire, Dyanne Rampling, Austen J Worth, Methap Sirin, Catharina Schuetz, Ansgar S Schulz, Manfred Hoenig, Adrian J Thrasher, Edward G Davies
Correction of both immunodeficiency and hypoparathyroidism by thymus transplantation in complete DiGeorge syndrome. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20 (5) (2019)
Elizabeth Rivers, Adrian J Thrasher
Wiskott-Aldrich syndrome protein: Emerging mechanisms in immunity. European journal of immunology 47 (11) (2017)
Ariane S I Standing, Dessislava Malinova, Ying Hong, Julien Record, Dale A Moulding, Michael P Blundell, Karolin Nowak, Hannah Jones, Ebun Omoyinmi, Kimberley C Gilmour, Alan Medlar, Horia Stanescu, Robert Kleta, Glenn Anderson, Sira Nanthapisal, Sonia Melo Gomes, Nigel Klein, Despina Eleftheriou, Adrian J Thrasher, Paul A Brogan
Autoinflammatory periodic fever, immunodeficiency, and thrombocytopenia (PFIT) caused by mutation in actin-regulatory gene WDR1. The Journal of experimental medicine 214 (1) (2016)