Kenneth G C Smith (Ken G C Smith)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 29

Top Topics

Respiratory Syndrome Coronavirus

Patients With Inflammatory Bowel Disease

Lipopolysaccharide Induced

Immune Response

Top Venues

Science advances

Nature immunology

Science immunology

The Journal of experimental medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Aimee L Hanson, Matthew P Mulè, Hélène Ruffieux, Frederica Mescia, Laura Bergamaschi, Victoria S Pelly, Lorinda Turner, Prasanti Kotagiri, null null, Berthold Göttgens, Christoph Hess, Nicholas Gleadall, John R Bradley, James A Nathan, Paul A Lyons, Alexander Drakesmith, Kenneth G C Smith
Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19. Nature immunology 25 (3) (2024)
Benjamin A Krishna, Eleanor Y Lim, Marina Metaxaki, Sarah E Jackson, Lenette Mactavous, null null, Paul A Lyons, Rainer Doffinger, John R Bradley, Kenneth G C Smith, John H Sinclair, Nicholas J Matheson, Paul J Lehner, Nyaradzai Sithole, Mark R Wills
Spontaneous, persistent, T cell-dependent IFN-γ release in patients who progress to Long Covid. Science advances 10 (8) (2024)
Benjamin A Krishna, Eleanor Y Lim, Marina Metaxaki, Sarah E Jackson, Lenette Mactavous, null null, Paul A Lyons, Rainer Doffinger, John R Bradley, Kenneth G C Smith, John H Sinclair, Nicholas J Matheson, Paul J Lehner, Nyaradzai Sithole, Mark R Wills
Spontaneous, persistent, T cell-dependent IFN-γ release in patients who progress to Long Covid. Science advances 10 (8) (2024)
Benjamin A Krishna, Eleanor Y Lim, Marina Metaxaki, Sarah E Jackson, Lenette Mactavous, null null, Paul A Lyons, Rainer Doffinger, John R Bradley, Kenneth G C Smith, John H Sinclair, Nicholas J Matheson, Paul J Lehner, Nyaradzai Sithole, Mark R Wills
Spontaneous, persistent, T cell-dependent IFN-γ release in patients who progress to Long Covid. Science advances 10 (8) (2024)
Munetomo Takahashi, Tsz Y So, Vitalina Chamberlain-Evans, Robert Hughes, Juan Carlos Yam-Puc, Katarzyna Kania, Michelle Ruhle, Tiffeney Mann, Martijn J Schuijs, Paul Coupland, Dean John Naisbitt, Timotheus Y F Halim, Paul A Lyons, Pietro Lió, Rahul Roychoudhuri, Klaus Okkenhaug, David J Adams, Kenneth G C Smith, Duncan Ian Jodrell, Michael A Chapman, James E D Thaventhiran
Intratumoral antigen signaling traps CD8 + T cells to confine exhaustion to the tumor site. Science immunology 9 (95) (2024)
Munetomo Takahashi, Tsz Y So, Vitalina Chamberlain-Evans, Robert Hughes, Juan Carlos Yam-Puc, Katarzyna Kania, Michelle Ruhle, Tiffeney Mann, Martijn J Schuijs, Paul Coupland, Dean John Naisbitt, Timotheus Y F Halim, Paul A Lyons, Pietro Lió, Rahul Roychoudhuri, Klaus Okkenhaug, David J Adams, Kenneth G C Smith, Duncan Ian Jodrell, Michael A Chapman, James E D Thaventhiran
Intratumoral antigen signaling traps CD8 + T cells to confine exhaustion to the tumor site. Science immunology 9 (95) (2024)
Munetomo Takahashi, Tsz Y So, Vitalina Chamberlain-Evans, Robert Hughes, Juan Carlos Yam-Puc, Katarzyna Kania, Michelle Ruhle, Tiffeney Mann, Martijn J Schuijs, Paul Coupland, Dean John Naisbitt, Timotheus Y F Halim, Paul A Lyons, Pietro Lió, Rahul Roychoudhuri, Klaus Okkenhaug, David J Adams, Kenneth G C Smith, Duncan Ian Jodrell, Michael A Chapman, James E D Thaventhiran
Intratumoral antigen signaling traps CD8 + T cells to confine exhaustion to the tumor site. Science immunology 9 (95) (2024)
Aimee L Hanson, Matthew P Mulè, Hélène Ruffieux, Frederica Mescia, Laura Bergamaschi, Victoria S Pelly, Lorinda Turner, Prasanti Kotagiri, null null, Berthold Göttgens, Christoph Hess, Nicholas Gleadall, John R Bradley, James A Nathan, Paul A Lyons, Alexander Drakesmith, Kenneth G C Smith
Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19. Nature immunology 25 (3) (2024)
Benjamin A Krishna, Eleanor Y Lim, Marina Metaxaki, Sarah E Jackson, Lenette Mactavous, null null, Paul A Lyons, Rainer Doffinger, John R Bradley, Kenneth G C Smith, John H Sinclair, Nicholas J Matheson, Paul J Lehner, Nyaradzai Sithole, Mark R Wills
Spontaneous, persistent, T cell-dependent IFN-γ release in patients who progress to Long Covid. Science advances 10 (8) (2024)
Aimee L Hanson, Matthew P Mulè, Hélène Ruffieux, Frederica Mescia, Laura Bergamaschi, Victoria S Pelly, Lorinda Turner, Prasanti Kotagiri, null null, Berthold Göttgens, Christoph Hess, Nicholas Gleadall, John R Bradley, James A Nathan, Paul A Lyons, Alexander Drakesmith, Kenneth G C Smith
Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19. Nature immunology 25 (3) (2024)
Aimee L Hanson, Matthew P Mulè, Hélène Ruffieux, Frederica Mescia, Laura Bergamaschi, Victoria S Pelly, Lorinda Turner, Prasanti Kotagiri, null null, Berthold Göttgens, Christoph Hess, Nicholas Gleadall, John R Bradley, James A Nathan, Paul A Lyons, Alexander Drakesmith, Kenneth G C Smith
Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19. Nature immunology 25 (3) (2024)
Aimee L Hanson, Matthew P Mulè, Hélène Ruffieux, Frederica Mescia, Laura Bergamaschi, Victoria S Pelly, Lorinda Turner, Prasanti Kotagiri, null null, Berthold Göttgens, Christoph Hess, Nicholas Gleadall, John R Bradley, James A Nathan, Paul A Lyons, Alexander Drakesmith, Kenneth G C Smith
Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19. Nature immunology 25 (3) (2024)
Munetomo Takahashi, Tsz Y So, Vitalina Chamberlain-Evans, Robert Hughes, Juan Carlos Yam-Puc, Katarzyna Kania, Michelle Ruhle, Tiffeney Mann, Martijn J Schuijs, Paul Coupland, Dean John Naisbitt, Timotheus Y F Halim, Paul A Lyons, Pietro Lió, Rahul Roychoudhuri, Klaus Okkenhaug, David J Adams, Kenneth G C Smith, Duncan Ian Jodrell, Michael A Chapman, James E D Thaventhiran
Intratumoral antigen signaling traps CD8 + T cells to confine exhaustion to the tumor site. Science immunology 9 (95) (2024)
Benjamin A Krishna, Eleanor Y Lim, Marina Metaxaki, Sarah E Jackson, Lenette Mactavous, null null, Paul A Lyons, Rainer Doffinger, John R Bradley, Kenneth G C Smith, John H Sinclair, Nicholas J Matheson, Paul J Lehner, Nyaradzai Sithole, Mark R Wills
Spontaneous, persistent, T cell-dependent IFN-γ release in patients who progress to Long Covid. Science advances 10 (8) (2024)
Aimee L Hanson, Matthew P Mulè, Hélène Ruffieux, Frederica Mescia, Laura Bergamaschi, Victoria S Pelly, Lorinda Turner, Prasanti Kotagiri, null null, Berthold Göttgens, Christoph Hess, Nicholas Gleadall, John R Bradley, James A Nathan, Paul A Lyons, Alexander Drakesmith, Kenneth G C Smith
Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19. Nature immunology 25 (3) (2024)
Benjamin A Krishna, Eleanor Y Lim, Marina Metaxaki, Sarah E Jackson, Lenette Mactavous, null null, Paul A Lyons, Rainer Doffinger, John R Bradley, Kenneth G C Smith, John H Sinclair, Nicholas J Matheson, Paul J Lehner, Nyaradzai Sithole, Mark R Wills
Spontaneous, persistent, T cell-dependent IFN-γ release in patients who progress to Long Covid. Science advances 10 (8) (2024)
William Rae, John M Sowerby, Dorit Verhoeven, Mariam M Youssef, Prasanti Kotagiri, Natalia Savinykh, Eve L Coomber, Alexis Boneparth, Angela Chan, Chun Gong, Machiel H Jansen, Romy du Long, Giorgia Santilli, Ilenia Simeoni, Jonathan Stephens, Kejia Wu, Marta Zinicola, Hana Lango Allen, Helen Baxendale, Dinakantha Kumararatne, Effrossyni Gkrania-Klotsas, Selma Cecilia Scheffler-Mendoza, Marco Antonio Yamazaki-Nakashimada, Laura Berrón Ruiz, Cesar Mauricio Rojas-Maruri, Saul Oswaldo Lugo-Reyes, Paul A Lyons, Anthony P Williams, Daniel James Hodson, Gail A Bishop, Adrian J Thrasher, David C Thomas, Michael P Murphy, Timothy J Vyse, Joshua D Milner, Taco W Kuijpers, Kenneth G C Smith
Immunodeficiency, autoimmunity, and increased risk of B cell malignancy in humans with TRAF3 mutations. Science immunology 7 (74) (2022)
Carlos Perez-Sanchez, Ariana Barbera Betancourt, Paul A Lyons, Zinan Z Zhang, Chenqu Suo, James C Lee, Eoin F McKinney, Louise K Modis, Christian Ellson, Kenneth G C Smith
miR-374a-5p regulates inflammatory genes and monocyte function in patients with inflammatory bowel disease. The Journal of experimental medicine 219 (5) (2022)
Dami Aderonke Collier, Isabella A T M Ferreira, Prasanti Kotagiri, Rawlings P Datir, Eleanor Y Lim, Emma Touizer, Bo Meng, Adam Abdullahi, null null, Anne Elmer, Nathalie Kingston, Barbara Graves, Emma Le Gresley, Daniela Caputo, Laura Bergamaschi, Kenneth G C Smith, John R Bradley, Lourdes Ceron-Gutierrez, Paulina Cortes-Acevedo, Gabriela Barcenas-Morales, Michelle A Linterman, Laura E McCoy, Chris Davis, Emma C Thomson, Paul A Lyons, Eoin McKinney, Rainer Doffinger, Mark Wills, Ravindra Kumar Gupta
Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2. Nature 596 (7872) (2021)
Louis-Pascal Xhonneux, Oliver Knight, Lernmark Åke, Ezio Bonifacio, William A Hagopian, Marian J Rewers, Jin Xiong She, Jorma Toppari, Hemang M Parikh, Kenneth G C Smith, Anette-Gabriele Ziegler, Beena Akolkar, Jeffrey P Krischer, Eoin F McKinney
Transcriptional networks in at-risk individuals identify signatures of type 1 diabetes progression. Science translational medicine 13 (587) (2021)
Emily Stephenson, Gary Reynolds, Rachel A Botting, Fernando J Calero-Nieto, Michael D Morgan, Zewen Kelvin Tuong, Karsten Bach, Waradon Sungnak, Kaylee B Worlock, Masahiro Yoshida, Natushiko Kumasaka, Katarzyna Kania, Justin Engelbert, Bayanne Olabi, Jarmila Stremenova Spegarova, Nicola K Wilson, Nicole Mende, Laura Jardine, Louis C S Gardner, Issac Goh, David Horsfall, Jim McGrath, Simone Webb, Michael William Mather, Rik G H Lindeboom, Emma Dann, Ni Huang, Krzysztof Polański, Elena Prigmore, Florian Gothe, Jonathan Scott, Rebecca P Payne, Kenneth F Baker, Aidan T Hanrath, Ina Schim van der Loeff, Andrew S Barr, Amada Sanchez-Gonzalez, Laura Bergamaschi, Frederica Mescia, Josephine L Barnes, Eliz Kilich, Angus de Wilton, Anita Saigal, Aarash Saleh, Samuel M Janes, Claire Mary Smith, Nusayhah Gopee, Caroline Wilson, Paul Coupland, Jonathan M Coxhead, Vladimir Yu Kiselev, Stijn van Dongen, Jaume Bacardit, Hamish W King, null null, Anthony J Rostron, A John Simpson, Sophie Hambleton, Elisa Laurenti, Paul A Lyons, Kerstin B Meyer, Marko Z Nikolić, Christopher J A Duncan, Kenneth G C Smith, Sarah A Teichmann, Menna R Clatworthy, John C Marioni, Berthold Göttgens, Muzlifah A Haniffa
Single-cell multi-omics analysis of the immune response in COVID-19. Nature medicine 27 (5) (2021)
Thomas S Fulford, Raelene Grumont, Rushika C Wirasinha, Darcy Ellis, Adele Barugahare, Stephen J Turner, Haroon Naeem, David Powell, Paul A Lyons, Kenneth G C Smith, Sebastian Scheer, Colby Zaph, Ulf Klein, Stephen R Daley, Steve Gerondakis
c-Rel employs multiple mechanisms to promote the thymic development and peripheral function of regulatory T cells in mice. European journal of immunology 51 (8) (2021)
Dami Aderonke Collier, Anna De Marco, Isabella A T M Ferreira, Bo Meng, Rawlings P Datir, Alexandra C Walls, Steven A Kemp, Jessica Bassi, Dora Pinto, Chiara Silacci-Fregni, Siro Bianchi, M Alejandra Tortorici, John Bowen, Katja Culap, Stefano Jaconi, Elisabetta Cameroni, Gyorgy Snell, Matteo S Pizzuto, Alessandra Franzetti Pellanda, Christian Garzoni, Agostino Riva, null null, Anne Elmer, Nathalie Kingston, Barbara Graves, Laura E McCoy, Kenneth G C Smith, John R Bradley, Nigel Temperton, Lourdes Ceron-Gutierrez, Gabriela Barcenas-Morales, null null, William Harvey, Herbert W Virgin, Antonio Lanzavecchia, Luca Piccoli, Rainer Doffinger, Mark Wills, David J Veesler, Davide Corti, Ravindra Kumar Gupta
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies. Nature 593 (7857) (2021)
Eoin F McKinney, Iona Cuthbertson, Kristina M Harris, Dawn E Smilek, Christopher Connor, Giulia Manferrari, Edward J Carr, Scott S Zamvil, Kenneth G C Smith
A CD8+ NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis. Nature communications 12 (1) (2021)
Timothy J Wilson, Simon Clare, Joseph Mikulin, Christopher M Johnson, Katherine Harcourt, Paul A Lyons, Gordon Dougan, Kenneth G C Smith
Signalling lymphocyte activation molecule family member 9 is found on select subsets of antigen-presenting cells and promotes resistance to Salmonella infection. Immunology 159 (4) (2020)
Wei Wei, Salih Tuna, Michael J Keogh, Katherine R Smith, Timothy J Aitman, Philip L Beales, David L H Bennett, Daniel P Gale, Maria A K Bitner-Glindzicz, Graeme C Black, Paul Brennan, Perry Mark Elliott, Frances A Flinter, R Andres Floto, Henry Houlden, Melita Irving, Ania Koziell, Eamonn R Maher, Hugh Stephen Markus, Nicholas W Morrell, William G Newman, Irene Roberts, John Andrew Sayer, Kenneth G C Smith, Jenny C Taylor, Hugh C Watkins, Andrew R Webster, Andrew O M Wilkie, Catherine Williamson, null null, null null, Sofie Ashford, Christopher J Penkett, Kathleen E Stirrups, Augusto Rendon, Willem H Ouwehand, John R Bradley, F Lucy Raymond, Mark Caulfield, Ernest Turro, Patrick F Chinnery
Germline selection shapes human mitochondrial DNA diversity. Science (New York, N.Y.) 364 (6442) (2019)
Sarah Spencer, Sevgi Köstel Bal, William Egner, Hana Lango Allen, Syed I Raza, Chi A Ma, Meltem Gürel, Yuan Zhang, Guangping Sun, Ruth A Sabroe, Daniel Greene, William Rae, Tala Shahin, Katarzyna Kania, Rico Chandra Ardy, Marini Thian, Emily Staples, Annika Pecchia-Bekkum, William P M Worrall, Jonathan Stephens, Matthew Brown, Salih Tuna, Melanie York, Fiona Shackley, Diarmuid Kerrin, Ravishankar B Sargur, Alison M Condliffe, Hamid Nawaz Tipu, Hye Sun Kuehn, Sergio D Rosenzweig, Ernest Turro, Simon Tavare, Adrian J Thrasher, Duncan Ian Jodrell, Kenneth G C Smith, Kaan Boztug, Joshua D Milner, James E D Thaventhiran
Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses. The Journal of experimental medicine 216 (9) (2019)
Zinan Z Zhang, Florian Gothe, Perrine Pennamen, John R James, David McDonald, Carlos P Mata, Yorgo Modis, Anas M Alazami, Meghan Acres, Wolfram Haller, Claire Bowen, Rainer Döffinger, Jan Sinclair, Shannon Brothers, Yu Zhang, Helen F Matthews, Sophie Naudion, Fanny Pelluard, Huda Alajlan, Yasuhiro Yamazaki, Luigi Daniele Notarangelo, James E D Thaventhiran, Karin R Engelhardt, Hamoud Al-Mousa, Sophie Hambleton, Caroline Rooryck, Kenneth G C Smith, Michael J Lenardo
Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance. The Journal of experimental medicine 216 (6) (2019)
David C Thomas, Simon Clare, John M Sowerby, Mercedes Calvo Pardo, Jatinder K Juss, David A Goulding, Louise van der Weyden, Daniel M L Storisteanu, Ananth Prakash, Marion Espéli, Shaun M Flint, James C Lee, Kim Hoenderdos, Leanne Kane, Katherine Harcourt, Subhankar Mukhopadhyay, Yagnesh Umrania, Robin Antrobus, James A Nathan, David J Adams, Alex Bateman, Jyoti Sharma Choudhary, Paul A Lyons, Alison M Condliffe, Edwin R Chilvers, Gordon Dougan, Kenneth G C Smith
Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity. The Journal of experimental medicine 214 (4) (2017)