Aisha A Alsfouk (Aisha Alsfouk)

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 42

Top Topics

Molecular Docking

Tyrosine Kinase

Top Venues

Molecules (Basel, Switzerland)

Life (Basel, Switzerland)

Journal of enzyme inhibition and medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Ibrahim H Eissa, Reda G Yousef, Eslam B Elkaeed, Aisha A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Ahmed Ismail, Hazem Elkady, Ahmed M Metwaly
New Theobromine Apoptotic Analogue with Anticancer Potential Targeting the EGFR Protein: Computational and In Vitro Studies. ACS omega 9 (14) (2024)
Aya Soudi, Onur Bender, İsmail Çelik, Amer Ali Abd El-Hafeez, Rumeysa Dogan, Arzu Atalay, Eslam B Elkaeed, Aisha A Alsfouk, El Shimaa M N Abdelhafez, Omar M Aly, Wolfgang Sippl, Taha Farouk Shehata Ali
Discovery and Anticancer Screening of Novel Oxindole-Based Derivative Bearing Pyridyl Group as Potent and Selective Dual FLT3/CDK2 Kinase Inhibitor. Pharmaceuticals (Basel, Switzerland) 17 (5) (2024)
Aisha A Alsfouk
Pyrazine-based small molecule kinase inhibitors: clinical applications and patent review (2019-2023). Future medicinal chemistry (2024)
Ibrahim H Eissa, Reda G Yousef, Eslam B Elkaeed, Aisha A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Ahmed Ismail, Hazem Elkady, Ahmed M Metwaly
New Theobromine Apoptotic Analogue with Anticancer Potential Targeting the EGFR Protein: Computational and In Vitro Studies. ACS omega 9 (14) (2024)
Aya Soudi, Onur Bender, İsmail Çelik, Amer Ali Abd El-Hafeez, Rumeysa Dogan, Arzu Atalay, Eslam B Elkaeed, Aisha A Alsfouk, El Shimaa M N Abdelhafez, Omar M Aly, Wolfgang Sippl, Taha Farouk Shehata Ali
Discovery and Anticancer Screening of Novel Oxindole-Based Derivative Bearing Pyridyl Group as Potent and Selective Dual FLT3/CDK2 Kinase Inhibitor. Pharmaceuticals (Basel, Switzerland) 17 (5) (2024)
Michael Atef Fawzy, Karim Hagag Ibrahim, Ashraf A Aly, Asmaa H Mohamed, Sara Mohamed Naguib Abdel Hafez, Walaa Yehia Abdelzaher, Eslam B Elkaeed, Aisha A Alsfouk, El Shimaa M N Abdelhafez
One-pot synthesis and pharmacological evaluation of new quinoline/pyrimido-diazepines as pulmonary antifibrotic agents. Future medicinal chemistry (2024)
Ibrahim H Eissa, Reda G Yousef, Eslam B Elkaeed, Aisha A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Ahmed Ismail, Hazem Elkady, Ahmed M Metwaly
New Theobromine Apoptotic Analogue with Anticancer Potential Targeting the EGFR Protein: Computational and In Vitro Studies. ACS omega 9 (14) (2024)
Christopher Riley, Usama M Ammar, Aisha A Alsfouk, Nahoum G Anthony, Jessica Baiget, Giacomo Berretta, David Breen, Judith Huggan, Christopher P Lawson, Kathryn McIntosh, Robin Plevin, Colin J Suckling, Louise C Young, Andrew Paul, Simon P Mackay
Design and Synthesis of Novel Aminoindazole-pyrrolo[2,3- b ]pyridine Inhibitors of IKKα That Selectively Perturb Cellular Non-Canonical NF-κB Signalling. Molecules (Basel, Switzerland) 29 (15) (2024)
Christopher Riley, Usama M Ammar, Aisha A Alsfouk, Nahoum G Anthony, Jessica Baiget, Giacomo Berretta, David Breen, Judith Huggan, Christopher P Lawson, Kathryn McIntosh, Robin Plevin, Colin J Suckling, Louise C Young, Andrew Paul, Simon P Mackay
Design and Synthesis of Novel Aminoindazole-pyrrolo[2,3- b ]pyridine Inhibitors of IKKα That Selectively Perturb Cellular Non-Canonical NF-κB Signalling. Molecules (Basel, Switzerland) 29 (15) (2024)
Eman A Sobh, Mohammed A Dahab, Eslam B Elkaeed, Aisha A Alsfouk, Ibrahim M Ibrahim, Ahmed M Metwaly, Ibrahim H Eissa
Discovery of new thieno[2,3- d ]pyrimidines as EGFR tyrosine kinase inhibitors for cancer treatment. Future medicinal chemistry (2023)
Ibrahim H Eissa, Reda G Yousef, Eslam B Elkaeed, Aisha A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Mohamed S Alesawy, Hazem Elkady, Ahmed M Metwaly
Anticancer derivative of the natural alkaloid, theobromine, inhibiting EGFR protein: Computer-aided drug discovery approach. PloS one 18 (3) (2023)
Ibrahim H Eissa, Reda G Yousef, Eslam B Elkaeed, Aisha A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Mohamed S Alesawy, Hazem Elkady, Ahmed M Metwaly
Anticancer derivative of the natural alkaloid, theobromine, inhibiting EGFR protein: Computer-aided drug discovery approach. PloS one 18 (3) (2023)
Ibrahim H Eissa, Reda G Yousef, Eslam B Elkaeed, Aisha A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Mohamed S Alesawy, Hazem Elkady, Ahmed M Metwaly
Anticancer derivative of the natural alkaloid, theobromine, inhibiting EGFR protein: Computer-aided drug discovery approach. PloS one 18 (3) (2023)
Ibrahim H Eissa, Reda G Yousef, Hazem Elkady, Aisha A Alsfouk, Bshra Ali A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Eslam B Elkaeed, Ahmed M Metwaly
A New Anticancer Semisynthetic Theobromine Derivative Targeting EGFR Protein: CADDD Study. Life (Basel, Switzerland) 13 (1) (2023)
Ashwag S Alanazi, Tebyan O Mirgany, Aisha A Alsfouk, Nawaf A Alsaif, A F M Motiur Rahman
Antiproliferative Activity, Multikinase Inhibition, Apoptosis- Inducing Effects and Molecular Docking of Novel Isatin-Purine Hybrids. Medicina (Kaunas, Lithuania) 59 (3) (2023)
Ibrahim H Eissa, Reda G Yousef, Hazem Elkady, Aisha A Alsfouk, Bshra Ali A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Eslam B Elkaeed, Ahmed M Metwaly
A New Anticancer Semisynthetic Theobromine Derivative Targeting EGFR Protein: CADDD Study. Life (Basel, Switzerland) 13 (1) (2023)
Ashwag S Alanazi, Tebyan O Mirgany, Aisha A Alsfouk, Nawaf A Alsaif, A F M Motiur Rahman
Antiproliferative Activity, Multikinase Inhibition, Apoptosis- Inducing Effects and Molecular Docking of Novel Isatin-Purine Hybrids. Medicina (Kaunas, Lithuania) 59 (3) (2023)
Ibrahim H Eissa, Reda G Yousef, Eslam B Elkaeed, Aisha A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Mohamed S Alesawy, Hazem Elkady, Ahmed M Metwaly
Anticancer derivative of the natural alkaloid, theobromine, inhibiting EGFR protein: Computer-aided drug discovery approach. PloS one 18 (3) (2023)
Ibrahim H Eissa, Reda G Yousef, Hazem Elkady, Aisha A Alsfouk, Bshra Ali A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Eslam B Elkaeed, Ahmed M Metwaly
A New Anticancer Semisynthetic Theobromine Derivative Targeting EGFR Protein: CADDD Study. Life (Basel, Switzerland) 13 (1) (2023)
Ashwag S Alanazi, Tebyan O Mirgany, Aisha A Alsfouk, Nawaf A Alsaif, A F M Motiur Rahman
Antiproliferative Activity, Multikinase Inhibition, Apoptosis- Inducing Effects and Molecular Docking of Novel Isatin-Purine Hybrids. Medicina (Kaunas, Lithuania) 59 (3) (2023)
Aisha A Alsfouk, Hanan M Alshibl, Najla A Altwaijry, Ashwag S Alanazi, Omkulthom Al Kamaly, Ahlam Sultan, Bshra Ali A Alsfouk
New Imadazopyrazines with CDK9 Inhibitory Activity as Anticancer and Antiviral: Synthesis, In Silico, and In Vitro Evaluation Approaches. Pharmaceuticals (Basel, Switzerland) 16 (7) (2023)
Ibrahim H Eissa, Reda G Yousef, Hazem Elkady, Aisha A Alsfouk, Bshra Ali A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Eslam B Elkaeed, Ahmed M Metwaly
A New Anticancer Semisynthetic Theobromine Derivative Targeting EGFR Protein: CADDD Study. Life (Basel, Switzerland) 13 (1) (2023)
Zeinolla Muldakhmetov, Serik Fazylov, Oral Nurkenov, Arstan Gazaliev, Akmaral Sarsenbekova, Irina Pustolaikina, Zhangeldy Nurmaganbetov, Olzhas Seilkhanov, Aisha A Alsfouk, Eslam B Elkaeed, Ibrahim H Eissa, Ahmed M Metwaly
Combined Computational and Experimental Studies of Anabasine Encapsulation by Beta-Cyclodextrin. Plants (Basel, Switzerland) 11 (17) (2022)
Eslam B Elkaeed, Ahmed M Metwaly, Mohamed S Alesawy, Abdulrahman M Saleh, Aisha A Alsfouk, Ibrahim H Eissa
Discovery of Potential SARS-CoV-2 Papain-like Protease Natural Inhibitors Employing a Multi-Phase In Silico Approach. Life (Basel, Switzerland) 12 (9) (2022)
Yerlan M Suleimen, Rani A Jose, Raigul N Suleimen, Margarita Yu Ishmuratova, Suzanne Toppet, Wim Dehaen, Aisha A Alsfouk, Eslam B Elkaeed, Ibrahim H Eissa, Ahmed M Metwaly
Isolation and In Silico SARS-CoV-2 Main Protease Inhibition Potential of Jusan Coumarin, a New Dicoumarin from Artemisia glauca . Molecules (Basel, Switzerland) 27 (7) (2022)
Mohammed S Taghour, Hazem Elkady, Wagdy M Eldehna, Nehal M El-Deeb, Ahmed M Kenawy, Eslam B Elkaeed, Aisha A Alsfouk, Mohamed S Alesawy, Ahmed M Metwaly, Ibrahim H Eissa
Design and synthesis of thiazolidine-2,4-diones hybrids with 1,2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: in-vitro anticancer evaluation and in-silico studies. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Mohammed S Taghour, Hazem A Mahdy, Maher H Gomaa, Ahmed Aglan, Mahmoud Gomaa Eldeib, Alaa Elwan, Mohammed A Dahab, Eslam B Elkaeed, Aisha A Alsfouk, Mohamed M Khalifa, Ibrahim H Eissa, Hazem Elkady
Benzoxazole derivatives as new VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, in silico studies, and antiproliferative evaluation. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Samaher S A Mahmoud, Eslam B Elkaeed, Aisha A Alsfouk, El Shimaa M N Abdelhafez
Molecular Docking and Dynamic Simulation Revealed the Potential Inhibitory Activity of Opioid Compounds Targeting the Main Protease of SARS-CoV-2. BioMed research international 2022 (2022)
Eslam B Elkaeed, Ibrahim H Eissa, Hazem Elkady, Ahmed Abdelalim, Ahmad M Alqaisi, Aisha A Alsfouk, Elwan Alaa, Ahmed M Metwaly
A Multistage In Silico Study of Natural Potential Inhibitors Targeting SARS-CoV-2 Main Protease. International journal of molecular sciences 23 (15) (2022)
Elwan Alaa, Abdallah E Abdallah, Hazem A Mahdy, Mohammed A Dahab, Mohammed S Taghour, Eslam B Elkaeed, Ahmed B M Mehany, Ahmed Nabeeh, Mohammed Adel, Aisha A Alsfouk, Hazem Elkady, Ibrahim H Eissa
Modified Benzoxazole-Based VEGFR-2 Inhibitors and Apoptosis Inducers: Design, Synthesis, and Anti-Proliferative Evaluation. Molecules (Basel, Switzerland) 27 (15) (2022)
Yerlan M Suleimen, Rani A Jose, Raigul N Suleimen, Christoph Arenz, Margarita Yu Ishmuratova, Suzanne Toppet, Wim Dehaen, Aisha A Alsfouk, Eslam B Elkaeed, Ibrahim H Eissa, Ahmed M Metwaly
Isolation and In Silico Anti-SARS-CoV-2 Papain-Like Protease Potentialities of Two Rare 2-Phenoxychromone Derivatives from Artemisia spp. Molecules (Basel, Switzerland) 27 (4) (2022)
Eslam B Elkaeed, Fadia S Youssef, Ibrahim H Eissa, Hazem Elkady, Aisha A Alsfouk, Mohamed L L Ashour, Mahmoud A El Hassab, Sahar M Abou-Seri, Ahmed M Metwaly
Multi-Step In Silico Discovery of Natural Drugs against COVID-19 Targeting Main Protease. International journal of molecular sciences 23 (13) (2022)
Samaher S A Mahmoud, Eslam B Elkaeed, Aisha A Alsfouk, El Shimaa M N Abdelhafez
Molecular Docking and Dynamic Simulation Revealed the Potential Inhibitory Activity of Opioid Compounds Targeting the Main Protease of SARS-CoV-2. BioMed research international 2022 (2022)
Eslam B Elkaeed, Reda G Yousef, Hazem Elkady, Aisha A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Ahmed M Metwaly, Ibrahim H Eissa
New Anticancer Theobromine Derivative Targeting EGFR WT and EGFR T790M : Design, Semi-Synthesis, In Silico, and In Vitro Anticancer Studies. Molecules (Basel, Switzerland) 27 (18) (2022)
Reda G Yousef, Albaraa Ibrahim, Mohamed M Khalifa, Wagdy M Eldehna, Ibraheem M M Gobaara, Ahmed B M Mehany, Eslam B Elkaeed, Aisha A Alsfouk, Ahmed M Metwaly, Ibrahim H Eissa
Discovery of new nicotinamides as apoptotic VEGFR-2 inhibitors: virtual screening, synthesis, anti-proliferative, immunomodulatory, ADMET, toxicity, and molecular dynamic simulation studies. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Aisha A Alsfouk, Hanan M Alshibl, Bshra Ali A Alsfouk, Najla A Altwaijry, Ebtehal S Al-Abdullah
Synthesis and Biological Evaluation of Imadazo[1,2- a ]pyrazines as Anticancer and Antiviral Agents through Inhibition of CDK9 and Human Coronavirus. Pharmaceuticals (Basel, Switzerland) 15 (7) (2022)
Ainara Iskineyeva, Serik Fazylov, Ryszhan Bakirova, Akmaral Sarsenbekova, Irina Pustolaikina, Olzhas Seilkhanov, Aisha A Alsfouk, Eslam B Elkaeed, Ibrahim H Eissa, Ahmed M Metwaly
Combined In Silico and Experimental Investigations of Resveratrol Encapsulation by Beta-Cyclodextrin. Plants (Basel, Switzerland) 11 (13) (2022)
Eslam B Elkaeed, Mohamed M Khalifa, Bshra Ali A Alsfouk, Aisha A Alsfouk, Abdul-Aziz M M El-Attar, Ibrahim H Eissa, Ahmed M Metwaly
The Discovery of Potential SARS-CoV-2 Natural Inhibitors among 4924 African Metabolites Targeting the Papain-like Protease: A Multi-Phase In Silico Approach. Metabolites 12 (11) (2022)
Ibrahim H Eissa, Mohamed M Khalifa, Eslam B Elkaeed, Elsayed E Hafez, Aisha A Alsfouk, Ahmed M Metwaly
In Silico Exploration of Potential Natural Inhibitors against SARS-Cov-2 nsp10. Molecules (Basel, Switzerland) 26 (20) (2021)
Heba A El Gizawy, Sylvia A Boshra, Ahmed Mostafa, Sara H Mahmoud, Muhammad I Ismail, Aisha A Alsfouk, Azza T Taher, Ahmed Ali Al-Karmalawy
Pimenta dioica (L.) Merr. Bioactive Constituents Exert Anti-SARS-CoV-2 and Anti-Inflammatory Activities: Molecular Docking and Dynamics, In Vitro, and In Vivo Studies. Molecules (Basel, Switzerland) 26 (19) (2021)
Mohamed S Alesawy, Eslam B Elkaeed, Aisha A Alsfouk, Ahmed M Metwaly, Ibrahim H Eissa
In Silico Screening of Semi-Synthesized Compounds as Potential Inhibitors for SARS-CoV-2 Papain-like Protease: Pharmacophoric Features, Molecular Docking, ADMET, Toxicity and DFT Studies. Molecules (Basel, Switzerland) 26 (21) (2021)
Aisha A Alsfouk
Small molecule inhibitors of cyclin-dependent kinase 9 for cancer therapy. Journal of enzyme inhibition and medicinal chemistry 36 (1) (2021)