Ibrahim H Eissa

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 88

Top Venues

Molecules (Basel, Switzerland)

Archiv der Pharmazie

Journal of enzyme inhibition and medicinal chemistry

RSC advances

Al-Azhar University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Al-Azhar University Nov 28 2017

Egypt

Associate professor :: Medicinal Chemistry

Publications

Ibrahim H Eissa, Reda G Yousef, Eslam B Elkaeed, Aisha A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Ahmed Ismail, Hazem Elkady, Ahmed M Metwaly
New Theobromine Apoptotic Analogue with Anticancer Potential Targeting the EGFR Protein: Computational and In Vitro Studies. ACS omega 9 (14) (2024)
Maged S Abdel-Kader, Mohamed M Radwan, Ahmed M Metwaly, Ibrahim H Eissa, Arno Hazekamp, Mahmoud A ElSohly
Chemistry and Pharmacology of Delta-8-Tetrahydrocannabinol. Molecules (Basel, Switzerland) 29 (6) (2024)
Maged S Abdel-Kader, Mohamed M Radwan, Ahmed M Metwaly, Ibrahim H Eissa, Arno Hazekamp, Mahmoud A ElSohly
Chemistry and Pharmacology of Delta-8-Tetrahydrocannabinol. Molecules (Basel, Switzerland) 29 (6) (2024)
Maged S Abdel-Kader, Mohamed M Radwan, Ahmed M Metwaly, Ibrahim H Eissa, Arno Hazekamp, Mahmoud A ElSohly
Chemistry and Pharmacology of Delta-8-Tetrahydrocannabinol. Molecules (Basel, Switzerland) 29 (6) (2024)
Mohamed H Abd El-Razek, Ibrahim H Eissa, Ahmed Ali Al-Karmalawy, Ahmed A Elrashedy, Ahmed H El-Desoky, Mohamed Aboelmagd, Tarik A Mohamed, Mohamed-Elamir F Hegazy
epi -Magnolin, a tetrahydrofurofuranoid lignan from the oleo-gum resin of Commiphora wightii , as inhibitor of pancreatic cancer cell proliferation, in-vitro and in-silico study. Journal of biomolecular structure & dynamics (2024)
Ibrahim H Eissa, Reda G Yousef, Eslam B Elkaeed, Aisha A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Ahmed Ismail, Hazem Elkady, Ahmed M Metwaly
New Theobromine Apoptotic Analogue with Anticancer Potential Targeting the EGFR Protein: Computational and In Vitro Studies. ACS omega 9 (14) (2024)
Ibrahim H Eissa, Reda G Yousef, Eslam B Elkaeed, Aisha A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Ahmed Ismail, Hazem Elkady, Ahmed M Metwaly
New Theobromine Apoptotic Analogue with Anticancer Potential Targeting the EGFR Protein: Computational and In Vitro Studies. ACS omega 9 (14) (2024)
Eman A Sobh, Mohammed A Dahab, Eslam B Elkaeed, Aisha A Alsfouk, Ibrahim M Ibrahim, Ahmed M Metwaly, Ibrahim H Eissa
Discovery of new thieno[2,3- d ]pyrimidines as EGFR tyrosine kinase inhibitors for cancer treatment. Future medicinal chemistry (2023)
Anas Ramadan Kotb, Abdallah E Abdallah, Hazem Elkady, Ibrahim H Eissa, Mohammed S Taghour, Dina Abed Bakhotmah, Tamer M Abdelghany, Mohamed Ayman El-Zahabi
Design, synthesis, anticancer evaluation, and in silico ADMET analysis of novel thalidomide analogs as promising immunomodulatory agents. RSC advances 13 (16) (2023)
Hazem Elkady, Osama A El-Dardir, Elwan Alaa, Mohammed S Taghour, Hazem A Mahdy, Mohammed A Dahab, Eslam B Elkaeed, Bshra A Alsfouk, Ibrahim M Ibrahim, Dalal Z Husein, Elsayed E Hafez, Amira Muhammad Galal Darwish, Ahmed M Metwaly, Ibrahim H Eissa
Synthesis, biological evaluation and computer-aided discovery of new thiazolidine-2,4-dione derivatives as potential antitumor VEGFR-2 inhibitors. RSC advances 13 (40) (2023)
Sara Shokry, Akram Hegazy, Ahmad M Abbas, Islam Mostafa, Ibrahim H Eissa, Ahmed M Metwaly, Galal Yahya, Assem M El-Shazly, Khaled M A Aboshanab, Ahmed Mostafa
Phytoestrogen β -Sitosterol Exhibits Potent In Vitro Antiviral Activity against Influenza A Viruses. Vaccines 11 (2) (2023)
Souad A El-Metwally, Hazem Elkady, Muhammad A Hagras, Eslam B Elkaeed, Bshra Ali A Alsfouk, Ahmed S Doghish, Ibrahim M Ibrahim, Mohammed S Taghour, Dalal Z Husein, Ahmed M Metwaly, Ibrahim H Eissa
Discovery of new VEGFR-2 inhibitors and apoptosis inducer-based thieno[2,3- d ]pyrimidine. Future medicinal chemistry (2023)
Abdulrahman M Saleh, Hazem A Mahdy, Mohamed Ayman El-Zahabi, Ahmed B M Mehany, Mohamed M Khalifa, Ibrahim H Eissa
Design, synthesis, in silico studies, and biological evaluation of novel pyrimidine-5-carbonitrile derivatives as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers. RSC advances 13 (32) (2023)
Ibrahim H Eissa, Reda G Yousef, Hazem Elkady, Eslam B Elkaeed, Aisha A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Mostafa A Elhendawy, Murrell Godfrey, Ahmed M Metwaly
Identification of new theobromine-based derivatives as potent VEGFR-2 inhibitors: design, semi-synthesis, biological evaluation, and in silico studies. RSC advances 13 (33) (2023)
Mohammed S Taghour, Hazem Elkady, Wagdy M Eldehna, Nehal El-Deeb, Ahmed M Kenawy, Abeer E Abd El-Wahab, Eslam B Elkaeed, Bshra A Alsfouk, Ahmed M Metwaly, Ibrahim H Eissa
Discovery of new quinoline and isatine derivatives as potential VEGFR-2 inhibitors: design, synthesis, antiproliferative, docking and MD simulation studies. Journal of biomolecular structure & dynamics (2023)
Eman A Sobh, Mohammed A Dahab, Eslam B Elkaeed, Bshra A Alsfouk, Ibrahim M Ibrahim, Ahmed M Metwaly, Ibrahim H Eissa
A novel thieno[2,3-d]pyrimidine derivative inhibiting vascular endothelial growth factor receptor-2: A story of computer-aided drug discovery. Drug development research (2023)
Ibrahim H Eissa, Reda G Yousef, Hazem Elkady, Aisha A Alsfouk, Bshra Ali A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Eslam B Elkaeed, Ahmed M Metwaly
A New Anticancer Semisynthetic Theobromine Derivative Targeting EGFR Protein: CADDD Study. Life (Basel, Switzerland) 13 (1) (2023)
Walid E Elgammal, Hazem Elkady, Hazem A Mahdy, Dalal Z Husein, Aisha A Alsfouk, Bshra A Alsfouk, Ibrahim M Ibrahim, Eslam B Elkaeed, Ahmed M Metwaly, Ibrahim H Eissa
Rationale design and synthesis of new apoptotic thiadiazole derivatives targeting VEGFR-2: computational and in vitro studies. RSC advances 13 (51) (2023)
Hazem A Mahdy, Hazem Elkady, Mohammed S Taghour, Elwan Alaa, Mohammed A Dahab, Mohamed A Elkady, Elsayed Ge Elsakka, Eslam B Elkaeed, Bshra Ali A Alsfouk, Ibrahim M Ibrahim, Ibrahim H Eissa, Ahmed M Metwaly
New theobromine derivatives inhibiting VEGFR-2: design, synthesis, antiproliferative, docking and molecular dynamics simulations. Future medicinal chemistry (2023)
Eman A Sobh, Mohammed A Dahab, Eslam B Elkaeed, Aisha A Alsfouk, Ibrahim M Ibrahim, Ahmed M Metwaly, Ibrahim H Eissa
Computer aided drug discovery (CADD) of a thieno[2,3- d ]pyrimidine derivative as a new EGFR inhibitor targeting the ribose pocket. Journal of biomolecular structure & dynamics (2023)
Ahmed A Gaber, Mohamed Sobhy, Abdallah Turky, Wagdy M Eldehna, Samiha A El-Sebaey, Souad A El-Metwally, Abeer M El-Naggar, Ibrahim M Ibrahim, Eslam B Elkaeed, Ahmed M Metwaly, Ibrahim H Eissa
New [1,2,4]triazolo[4,3-c]quinazolines as intercalative Topo II inhibitors: Design, synthesis, biological evaluation, and in silico studies. PloS one 18 (1) (2023)
Faez Ahmmed, Samiah Hamad Al-Mijalli, Ahmed M E Elkhalifa, Ibrahim H Eissa, Ferdausi Ali, Ajmal R Bhat, Joazaizulfazli Jamalis, Taibi Ben Hadda, Sarkar Mohammad Abe Kawsar
Galactoside-Based Molecule Enhanced Antimicrobial Activity through Acyl Moiety Incorporation: Synthesis and In Silico Exploration for Therapeutic Target. Pharmaceuticals (Basel, Switzerland) 16 (7) (2023)
Ibrahim H Eissa, Reda G Yousef, Hazem Elkady, Aisha A Alsfouk, Bshra Ali A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Eslam B Elkaeed, Ahmed M Metwaly
A New Anticancer Semisynthetic Theobromine Derivative Targeting EGFR Protein: CADDD Study. Life (Basel, Switzerland) 13 (1) (2023)
Mohammed A Dahab, Hazem A Mahdy, Hazem Elkady, Mohammed S Taghour, Alaa Elwan, Mohamed A Elkady, Elsayed G E Elsakka, Eslam B Elkaeed, Aisha A Alsfouk, Ibrahim M Ibrahim, Ahmed M Metwaly, Ibrahim H Eissa
Semi-synthesized anticancer theobromine derivatives targeting VEGFR-2: in silico and in vitro evaluations. Journal of biomolecular structure & dynamics (2023)
Omnia R Elbatrawy, Mohamed Hagras, Moshira A El Deeb, Fatimah Agili, Maghawry Hegazy, Ahmed A El-Husseiny, Mahmoud Mohamed Mokhtar, Samy Y Elkhawaga, Ibrahim H Eissa, Samar A El-Kalyoubi
Discovery of New Uracil and Thiouracil Derivatives as Potential HDAC Inhibitors. Pharmaceuticals (Basel, Switzerland) 16 (7) (2023)
Ahmed A Gaber, Mohamed Sobhy, Abdallah Turky, Wagdy M Eldehna, Samiha A El-Sebaey, Souad A El-Metwally, Abeer M El-Naggar, Ibrahim M Ibrahim, Eslam B Elkaeed, Ahmed M Metwaly, Ibrahim H Eissa
New [1,2,4]triazolo[4,3-c]quinazolines as intercalative Topo II inhibitors: Design, synthesis, biological evaluation, and in silico studies. PloS one 18 (1) (2023)
Walid E Elgammal, Hazem Elkady, Hazem A Mahdy, Dalal Z Husein, Aisha A Alsfouk, Bshra A Alsfouk, Ibrahim M Ibrahim, Eslam B Elkaeed, Ahmed M Metwaly, Ibrahim H Eissa
Rationale design and synthesis of new apoptotic thiadiazole derivatives targeting VEGFR-2: computational and in vitro studies. RSC advances 13 (51) (2023)
Ahmed A Gaber, Mohamed Sobhy, Abdallah Turky, Wagdy M Eldehna, Samiha A El-Sebaey, Souad A El-Metwally, Abeer M El-Naggar, Ibrahim M Ibrahim, Eslam B Elkaeed, Ahmed M Metwaly, Ibrahim H Eissa
New [1,2,4]triazolo[4,3-c]quinazolines as intercalative Topo II inhibitors: Design, synthesis, biological evaluation, and in silico studies. PloS one 18 (1) (2023)
Sara Shokry, Akram Hegazy, Ahmad M Abbas, Islam Mostafa, Ibrahim H Eissa, Ahmed M Metwaly, Galal Yahya, Assem M El-Shazly, Khaled M A Aboshanab, Ahmed Mostafa
Phytoestrogen β -Sitosterol Exhibits Potent In Vitro Antiviral Activity against Influenza A Viruses. Vaccines 11 (2) (2023)
Ahmed A Gaber, Mohamed Sobhy, Abdallah Turky, Wagdy M Eldehna, Samiha A El-Sebaey, Souad A El-Metwally, Abeer M El-Naggar, Ibrahim M Ibrahim, Eslam B Elkaeed, Ahmed M Metwaly, Ibrahim H Eissa
New [1,2,4]triazolo[4,3-c]quinazolines as intercalative Topo II inhibitors: Design, synthesis, biological evaluation, and in silico studies. PloS one 18 (1) (2023)
Eman A Sobh, Mohammed A Dahab, Eslam B Elkaeed, Aisha A Alsfouk, Ibrahim M Ibrahim, Ahmed M Metwaly, Ibrahim H Eissa
Design, synthesis, docking, MD simulations, and anti-proliferative evaluation of thieno[2,3- d ]pyrimidine derivatives as new EGFR inhibitors. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Ibrahim H Eissa, Reda G Yousef, Hazem Elkady, Aisha A Alsfouk, Bshra Ali A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Eslam B Elkaeed, Ahmed M Metwaly
A New Anticancer Semisynthetic Theobromine Derivative Targeting EGFR Protein: CADDD Study. Life (Basel, Switzerland) 13 (1) (2023)
Omnia R Elbatrawy, Moshira A El Deeb, Mohamed Hagras, Fatimah Agili, Maghawry Hegazy, Ahmed A El-Husseiny, Mohamed A Elkady, Ibrahim H Eissa, Samar A El-Kalyoubi
New thiouracil derivatives as histone deacetylase inhibitors and apoptosis inducers: design, synthesis and anticancer evaluation. Future medicinal chemistry (2023)
Souad A El-Metwally, Hazem Elkady, Mohamed Hagras, Dalal Z Husein, Ibrahim M Ibrahim, Mohammed S Taghour, Hesham A El-Mahdy, Ahmed Ismail, Bshra A Alsfouk, Eslam B Elkaeed, Ahmed M Metwaly, Ibrahim H Eissa
Design, synthesis, anti-proliferative evaluation, docking, and MD simulation studies of new thieno[2,3- d ]pyrimidines targeting VEGFR-2. RSC advances 13 (33) (2023)
Reda G Yousef, Ibrahim H Eissa, Hazem Elkady, Wagdy M Eldehna, Ahmed B M Mehany, Ahmed Nabeeh, Ibrahim M Ibrahim, Alaa Elwan, Mohamed Ayman El-Zahabi
New nicotinamide derivatives as potential anticancer agents targeting VEGFR-2: design, synthesis, in vitro , and in silico studies. Journal of biomolecular structure & dynamics (2023)
Ibrahim H Eissa, Reda G Yousef, Hazem Elkady, Aisha A Alsfouk, Bshra Ali A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Eslam B Elkaeed, Ahmed M Metwaly
A New Anticancer Semisynthetic Theobromine Derivative Targeting EGFR Protein: CADDD Study. Life (Basel, Switzerland) 13 (1) (2023)
Eslam B Elkaeed, Reda G Yousef, Mohamed M Khalifa, Albaraa Ibrahim, Ahmed B M Mehany, Ibraheem M M Gobaara, Bshra Ali A Alsfouk, Wagdy M Eldehna, Ahmed M Metwaly, Ibrahim H Eissa, Mohamed Ayman El-Zahabi
Discovery of New VEGFR-2 Inhibitors: Design, Synthesis, Anti-Proliferative Evaluation, Docking, and MD Simulation Studies. Molecules (Basel, Switzerland) 27 (19) (2022)
Mohammed S Taghour, Hazem Elkady, Wagdy M Eldehna, Nehal El-Deeb, Ahmed M Kenawy, Eslam B Elkaeed, Bshra A Alsfouk, Mohamed S Alesawy, Dalal Z Husein, Ahmed M Metwaly, Ibrahim H Eissa
Design, synthesis, anti-proliferative evaluation, docking, and MD simulations studies of new thiazolidine-2,4-diones targeting VEGFR-2 and apoptosis pathway. PloS one 17 (9) (2022)
Salih Osman Mohammed, Sayed H El El Ashry, Asaad Khalid, Mohamed R Amer, Ahmed M Metwaly, Ibrahim H Eissa, Eslam B Elkaeed, Ahmed Elshobaky, Elsayed E Hafez
Expression, Purification, and Comparative Inhibition of Helicobacter pylori Urease by Regio-Selectively Alkylated Benzimidazole 2-Thione Derivatives. Molecules (Basel, Switzerland) 27 (3) (2022)
Zeinolla Muldakhmetov, Serik Fazylov, Oral Nurkenov, Arstan Gazaliev, Akmaral Sarsenbekova, Irina Pustolaikina, Zhangeldy Nurmaganbetov, Olzhas Seilkhanov, Aisha A Alsfouk, Eslam B Elkaeed, Ibrahim H Eissa, Ahmed M Metwaly
Combined Computational and Experimental Studies of Anabasine Encapsulation by Beta-Cyclodextrin. Plants (Basel, Switzerland) 11 (17) (2022)
Ibrahim H Eissa, Radwan El-Haggar, Mohammed A Dahab, Marwa F Ahmed, Hazem A Mahdy, Reem I Alsantali, Alaa Elwan, Nicolas Masurier, Samar S Fatahala
Design, synthesis, molecular modeling and biological evaluation of novel Benzoxazole-Benzamide conjugates via a 2-Thioacetamido linker as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Eslam B Elkaeed, Reda G Yousef, Hazem Elkady, Ibraheem M M Gobaara, Bshra Ali A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Ahmed M Metwaly, Ibrahim H Eissa
Design, Synthesis, Docking, DFT, MD Simulation Studies of a New Nicotinamide-Based Derivative: In Vitro Anticancer and VEGFR-2 Inhibitory Effects. Molecules (Basel, Switzerland) 27 (14) (2022)
Mohamed S Alesawy, Mohamed-Kamal Ibrahim, Ibrahim H Eissa, Khaled El-Adl
Design, synthesis, in silico ADMET, docking, and antiproliferative evaluations of [1,2,4]triazolo[4,3-c]quinazolines as classical DNA intercalators. Archiv der Pharmazie 355 (4) (2022)
Ahmed A Gaber, Mohamed Sobhy, Abdallah Turky, Hanan Gaber Abdulwahab, Ahmed Ali Al-Karmalawy, Mostafa A Elhendawy, Mohamed M Radwan, Eslam B Elkaeed, Ibrahim M Ibrahim, Heba S A Elzahabi, Ibrahim H Eissa
Discovery of new 1 H -pyrazolo[3,4- d ]pyrimidine derivatives as anticancer agents targeting EGFR WT and EGFR T790M . Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Reda G Yousef, Alaa Elwan, Ibraheem M M Gobaara, Ahmed B M Mehany, Wagdy M Eldehna, Souad A El-Metwally, Bshra A Alsfouk, Eslam B Elkaeed, Ahmed M Metwaly, Ibrahim H Eissa
Anti-cancer and immunomodulatory evaluation of new nicotinamide derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: in vitro and in silico studies. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Eslam B Elkaeed, Ahmed M Metwaly, Mohamed S Alesawy, Abdulrahman M Saleh, Aisha A Alsfouk, Ibrahim H Eissa
Discovery of Potential SARS-CoV-2 Papain-like Protease Natural Inhibitors Employing a Multi-Phase In Silico Approach. Life (Basel, Switzerland) 12 (9) (2022)
Anas Ramadan Kotb, Dina A Bakhotmah, Abdallah E Abdallah, Hazem Elkady, Mohammed S Taghour, Ibrahim H Eissa, Mohamed Ayman El-Zahabi
Design, synthesis, and biological evaluation of novel bioactive thalidomide analogs as anticancer immunomodulatory agents. RSC advances 12 (52) (2022)
Reda G Yousef, Hazem Elkady, Eslam B Elkaeed, Ibraheem M M Gobaara, Hanan A Al-Ghulikah, Dalal Z Husein, Ibrahim M Ibrahim, Ahmed M Metwaly, Ibrahim H Eissa
( E )- N -(3-(1-(2-(4-(2,2,2-Trifluoroacetamido)benzoyl)hydrazono)ethyl)phenyl)nicotinamide: A Novel Pyridine Derivative for Inhibiting Vascular Endothelial Growth Factor Receptor-2: Synthesis, Computational, and Anticancer Studies. Molecules (Basel, Switzerland) 27 (22) (2022)
Yerlan M Suleimen, Rani A Jose, Raigul N Suleimen, Margarita Yu Ishmuratova, Suzanne Toppet, Wim Dehaen, Aisha A Alsfouk, Eslam B Elkaeed, Ibrahim H Eissa, Ahmed M Metwaly
Isolation and In Silico SARS-CoV-2 Main Protease Inhibition Potential of Jusan Coumarin, a New Dicoumarin from Artemisia glauca . Molecules (Basel, Switzerland) 27 (7) (2022)
Khaled El-Adl, Helmy M Sakr, Reda G Yousef, Ahmed B M Mehany, Hamada S Abulkhair, Ibrahim H Eissa
New quinoxalin-2(1H)-one-derived VEGFR-2 inhibitors: Design, synthesis, in vitro anticancer evaluations, in silico ADMET, and docking studies. Archiv der Pharmazie 355 (7) (2022)
Eslam B Elkaeed, Mohammed S Taghour, Hazem A Mahdy, Wagdy M Eldehna, Nehal M El-Deeb, Ahmed M Kenawy, Bshra A Alsfouk, Mohammed A Dahab, Ahmed M Metwaly, Ibrahim H Eissa, Mohamed A El-Zahabi
New quinoline and isatin derivatives as apoptotic VEGFR-2 inhibitors: design, synthesis, anti-proliferative activity, docking, ADMET, toxicity, and MD simulation studies. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Mohammed S Taghour, Hazem Elkady, Wagdy M Eldehna, Nehal M El-Deeb, Ahmed M Kenawy, Eslam B Elkaeed, Aisha A Alsfouk, Mohamed S Alesawy, Ahmed M Metwaly, Ibrahim H Eissa
Design and synthesis of thiazolidine-2,4-diones hybrids with 1,2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: in-vitro anticancer evaluation and in-silico studies. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Ibrahim H Eissa, Mohamed-Kamal Ibrahim, Mohamed S Alesawy, Khaled El-Adl
Antiproliferative evaluations of triazoloquinazolines as classical DNA intercalators: Design, synthesis, ADMET profile, and molecular docking. Archiv der Pharmazie 355 (5) (2022)
Mohammed S Taghour, Hazem A Mahdy, Maher H Gomaa, Ahmed Aglan, Mahmoud Gomaa Eldeib, Alaa Elwan, Mohammed A Dahab, Eslam B Elkaeed, Aisha A Alsfouk, Mohamed M Khalifa, Ibrahim H Eissa, Hazem Elkady
Benzoxazole derivatives as new VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, in silico studies, and antiproliferative evaluation. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Ahmed E Azab, Mohamed S Alesawy, Wagdy M Eldehna, Alaa Elwan, Ibrahim H Eissa
New [1,2,4]triazolo[4,3-c]quinazoline derivatives as vascular endothelial growth factor receptor-2 inhibitors and apoptosis inducers: Design, synthesis, docking, and antiproliferative evaluation. Archiv der Pharmazie 355 (10) (2022)
Ahmed Khalil, Amany S El-Khouly, Eslam B Elkaeed, Ibrahim H Eissa
The Inhibitory Potential of 2'-dihalo Ribonucleotides against HCV: Molecular Docking, Molecular Simulations, MM-BPSA, and DFT Studies. Molecules (Basel, Switzerland) 27 (14) (2022)
Eslam B Elkaeed, Ibrahim H Eissa, Hazem Elkady, Ahmed Abdelalim, Ahmad M Alqaisi, Aisha A Alsfouk, Elwan Alaa, Ahmed M Metwaly
A Multistage In Silico Study of Natural Potential Inhibitors Targeting SARS-CoV-2 Main Protease. International journal of molecular sciences 23 (15) (2022)
Ahmed M Metwaly, Eslam B Elkaeed, Bshra Ali A Alsfouk, Abdulrahman M Saleh, Ahmad E Mostafa, Ibrahim H Eissa
The Computational Preventive Potential of the Rare Flavonoid, Patuletin, Isolated from Tagetes patula , against SARS-CoV-2. Plants (Basel, Switzerland) 11 (14) (2022)
Elwan Alaa, Abdallah E Abdallah, Hazem A Mahdy, Mohammed A Dahab, Mohammed S Taghour, Eslam B Elkaeed, Ahmed B M Mehany, Ahmed Nabeeh, Mohammed Adel, Aisha A Alsfouk, Hazem Elkady, Ibrahim H Eissa
Modified Benzoxazole-Based VEGFR-2 Inhibitors and Apoptosis Inducers: Design, Synthesis, and Anti-Proliferative Evaluation. Molecules (Basel, Switzerland) 27 (15) (2022)
Yerlan M Suleimen, Rani A Jose, Raigul N Suleimen, Christoph Arenz, Margarita Yu Ishmuratova, Suzanne Toppet, Wim Dehaen, Aisha A Alsfouk, Eslam B Elkaeed, Ibrahim H Eissa, Ahmed M Metwaly
Isolation and In Silico Anti-SARS-CoV-2 Papain-Like Protease Potentialities of Two Rare 2-Phenoxychromone Derivatives from Artemisia spp. Molecules (Basel, Switzerland) 27 (4) (2022)
Eslam B Elkaeed, Fadia S Youssef, Ibrahim H Eissa, Hazem Elkady, Aisha A Alsfouk, Mohamed L L Ashour, Mahmoud A El Hassab, Sahar M Abou-Seri, Ahmed M Metwaly
Multi-Step In Silico Discovery of Natural Drugs against COVID-19 Targeting Main Protease. International journal of molecular sciences 23 (13) (2022)
Anas Ramadan Kotb, Dina A Bakhotmah, Abdallah E Abdallah, Hazem Elkady, Mohammed S Taghour, Ibrahim H Eissa, Mohamed Ayman El-Zahabi
Design, synthesis, and biological evaluation of novel bioactive thalidomide analogs as anticancer immunomodulatory agents. RSC advances 12 (52) (2022)
Yerlan M Suleimen, Rani A Jose, Raigul N Suleimen, Christoph Arenz, Margarita Yu Ishmuratova, Suzanne Toppet, Wim Dehaen, Bshra Ali A Alsfouk, Eslam B Elkaeed, Ibrahim H Eissa, Ahmed M Metwaly
Jusanin, a New Flavonoid from Artemisia commutata with an In Silico Inhibitory Potential against the SARS-CoV-2 Main Protease. Molecules (Basel, Switzerland) 27 (5) (2022)
Eslam B Elkaeed, Reda G Yousef, Hazem Elkady, Aisha A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Ahmed M Metwaly, Ibrahim H Eissa
New Anticancer Theobromine Derivative Targeting EGFR WT and EGFR T790M : Design, Semi-Synthesis, In Silico, and In Vitro Anticancer Studies. Molecules (Basel, Switzerland) 27 (18) (2022)
Heba S A El-Zahabi, Eman S Nossier, Rania A Alasfoury, May El-Manawaty, Sara M Sayed, Eslam B Elkaeed, Ahmed M Metwaly, Mohamed Hagras, Ibrahim H Eissa
Design, synthesis, and anti-cancer evaluation of new pyrido[2,3-d]pyrimidin-4(3H)-one derivatives as potential EGFRWT and EGFRT790M inhibitors and apoptosis inducers. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Reda G Yousef, Wagdy M Eldehna, Elwan Alaa, Abdelaziz S Abdelaziz, Ahmed B M Mehany, Ibraheem M M Gobaara, Bshra Ali A Alsfouk, Eslam B Elkaeed, Ahmed M Metwaly, Ibrahim H Eissa
Design, Synthesis, In Silico and In Vitro Studies of New Immunomodulatory Anticancer Nicotinamide Derivatives Targeting VEGFR-2. Molecules (Basel, Switzerland) 27 (13) (2022)
Khaled El-Adl, Mohamed-Kamal Ibrahim, Mohamed S Alesawy, Ibrahim H Eissa
Triazoloquinazoline derived classical DNA intercalators: Design, synthesis, in silico ADME profile, docking, and antiproliferative evaluations. Archiv der Pharmazie 355 (6) (2022)
Ibrahim H Eissa, Mohamed S Alesawy, Abdulrahman M Saleh, Eslam B Elkaeed, Bshra Ali A Alsfouk, Abdul-Aziz M M El-Attar, Ahmed M Metwaly
Ligand and Structure-Based In Silico Determination of the Most Promising SARS-CoV-2 nsp16-nsp10 2'- o -Methyltransferase Complex Inhibitors among 3009 FDA Approved Drugs. Molecules (Basel, Switzerland) 27 (7) (2022)
Reda G Yousef, Albaraa Ibrahim, Mohamed M Khalifa, Wagdy M Eldehna, Ibraheem M M Gobaara, Ahmed B M Mehany, Eslam B Elkaeed, Aisha A Alsfouk, Ahmed M Metwaly, Ibrahim H Eissa
Discovery of new nicotinamides as apoptotic VEGFR-2 inhibitors: virtual screening, synthesis, anti-proliferative, immunomodulatory, ADMET, toxicity, and molecular dynamic simulation studies. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Mohamed Hagras, Marwa A Saleh, Rogy R Ezz Eldin, Abdelrahman A Abuelkhir, Emad Gamil Khidr, Ahmed A El-Husseiny, Hesham A El-Mahdy, Eslam B Elkaeed, Ibrahim H Eissa
1,3,4-Oxadiazole-naphthalene hybrids as potential VEGFR-2 inhibitors: design, synthesis, antiproliferative activity, apoptotic effect, and in silico studies. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Ainara Iskineyeva, Serik Fazylov, Ryszhan Bakirova, Akmaral Sarsenbekova, Irina Pustolaikina, Olzhas Seilkhanov, Aisha A Alsfouk, Eslam B Elkaeed, Ibrahim H Eissa, Ahmed M Metwaly
Combined In Silico and Experimental Investigations of Resveratrol Encapsulation by Beta-Cyclodextrin. Plants (Basel, Switzerland) 11 (13) (2022)
Yerlan M Suleimen, Rani A Jose, Gulnur K Mamytbekova, Raigul N Suleimen, Margarita Yu Ishmuratova, Wim Dehaen, Bshra Ali A Alsfouk, Eslam B Elkaeed, Ibrahim H Eissa, Ahmed M Metwaly
Isolation and In Silico Inhibitory Potential against SARS-CoV-2 RNA Polymerase of the Rare Kaempferol 3- O -(6″- O -acetyl)-Glucoside from Calligonum tetrapterum . Plants (Basel, Switzerland) 11 (15) (2022)
Eslam B Elkaeed, Mohamed M Khalifa, Bshra Ali A Alsfouk, Aisha A Alsfouk, Abdul-Aziz M M El-Attar, Ibrahim H Eissa, Ahmed M Metwaly
The Discovery of Potential SARS-CoV-2 Natural Inhibitors among 4924 African Metabolites Targeting the Papain-like Protease: A Multi-Phase In Silico Approach. Metabolites 12 (11) (2022)
Eslam B Elkaeed, Reda G Yousef, Hazem Elkady, Ahmed B M Mehany, Bshra A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Ahmed M Metwaly, Ibrahim H Eissa
In silico , in vitro VEGFR-2 inhibition, and anticancer activity of a 3-(hydrazonomethyl)naphthalene-2-ol derivative. Journal of biomolecular structure & dynamics (2022)
Fathalla Khedr, Mohamed-Kamal Ibrahim, Ibrahim H Eissa, Hamada S Abulkhair, Khaled El-Adl
Phthalazine-based VEGFR-2 inhibitors: Rationale, design, synthesis, in silico, ADMET profile, docking, and anticancer evaluations. Archiv der Pharmazie 354 (11) (2021)
Khaled El-Adl, Mohamed K Ibrahim, Fathalla Khedr, Hamada S Abulkhair, Ibrahim H Eissa
Design, synthesis, docking, and anticancer evaluations of phthalazines as VEGFR-2 inhibitors. Archiv der Pharmazie (2021)
Ibrahim H Eissa, Mohamed M Khalifa, Eslam B Elkaeed, Elsayed E Hafez, Aisha A Alsfouk, Ahmed M Metwaly
In Silico Exploration of Potential Natural Inhibitors against SARS-Cov-2 nsp10. Molecules (Basel, Switzerland) 26 (20) (2021)
A F M Motiur Rahman, Elwan Alaa, Nawaf A Alsaif, Ahmad J Obaidullah, Hamad M Al Kahtani, Abdulrahman A Al-Mehizia, Sultan M Alsubaie, Mohammed S Taghour, Ibrahim H Eissa
Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies. Journal of enzyme inhibition and medicinal chemistry 36 (1) (2021)
Amr El-Demerdash, Ahmed M Metwaly, Afnan Hassan, Tarek Mohamed Abd El-Aziz, Eslam B Elkaeed, Ibrahim H Eissa, Reem K Arafa, James D Stockand
Comprehensive Virtual Screening of the Antiviral Potentialities of Marine Polycyclic Guanidine Alkaloids against SARS-CoV-2 (COVID-19). Biomolecules 11 (3) (2021)
Feng Ran, Wendong Li, Yi Qin, Tong Yu, Zhao Liu, Min Zhou, Cheng Liu, Tong Qiao, Xiaoqiang Li, Reda G Yousef, Ibrahim H Eissa, Mohamed M Khalifa
Inhibition of Vascular Smooth Muscle and Cancer Cell Proliferation by New VEGFR Inhibitors and Their Immunomodulator Effect: Design, Synthesis, and Biological Evaluation. Oxidative medicine and cellular longevity 2021 (2021)
Mohamed S Alesawy, Abdallah E Abdallah, Mohammed S Taghour, Eslam B Elkaeed, Ibrahim H Eissa, Ahmed M Metwaly
In Silico Studies of Some Isoflavonoids as Potential Candidates against COVID-19 Targeting Human ACE2 (hACE2) and Viral Main Protease (Mpro). Molecules (Basel, Switzerland) 26 (9) (2021)
Mohamed S Alesawy, Eslam B Elkaeed, Aisha A Alsfouk, Ahmed M Metwaly, Ibrahim H Eissa
In Silico Screening of Semi-Synthesized Compounds as Potential Inhibitors for SARS-CoV-2 Papain-like Protease: Pharmacophoric Features, Molecular Docking, ADMET, Toxicity and DFT Studies. Molecules (Basel, Switzerland) 26 (21) (2021)
Mohammed M Alanazi, Hazem Elkady, Nawaf A Alsaif, Ahmad J Obaidullah, Hamad M Al Kahtani, Manal M Alanazi, Madhawi A Alharbi, Ibrahim H Eissa, Mohammed A Dahab
New quinoxaline-based VEGFR-2 inhibitors: design, synthesis, and antiproliferative evaluation with in silico docking, ADMET, toxicity, and DFT studies. RSC advances 11 (48) (2021)
Khaled El-Adl, Mohamed-Kamal Ibrahim, Fathalla Khedr, Hamada S Abulkhair, Ibrahim H Eissa
N-Substituted-4-phenylphthalazin-1-amine-derived VEGFR-2 inhibitors: Design, synthesis, molecular docking, and anticancer evaluation studies. Archiv der Pharmazie 354 (3) (2020)
Abeer M El-Naggar, Ibrahim H Eissa, Amany Belal, Amira A El-Sayed
Design, eco-friendly synthesis, molecular modeling and anticancer evaluation of thiazol-5(4 H )-ones as potential tubulin polymerization inhibitors targeting the colchicine binding site. RSC advances 10 (5) (2020)
Mohamed S Alesawy, Ahmed Ali Al-Karmalawy, Eslam B Elkaeed, Mohamed Alswah, Ahmed B M Mehany, Mohammed S Taghour, Ibrahim H Eissa
Design and discovery of new 1,2,4-triazolo[4,3-c]quinazolines as potential DNA intercalators and topoisomerase II inhibitors. Archiv der Pharmazie 354 (3) (2020)
Ibrahim H Eissa, Ahmed M Metwaly, Amany Belal, Ahmed B M Mehany, Rezk R Ayyad, Khaled El-Adl, Hazem A Mahdy, Mohammed S Taghour, Kamal M A El-Gamal, Mohamad E El-Sawah, Souad A Elmetwally, Mostafa A Elhendawy, Mohamed M Radwan, Mahmoud A ElSohly
Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors. Archiv der Pharmazie 352 (11) (2019)
Abdel-Ghany A El-Helby, Helmy Sakr, Ibrahim H Eissa, Ahmed A Al-Karmalawy, Khaled El-Adl
Benzoxazole/benzothiazole-derived VEGFR-2 inhibitors: Design, synthesis, molecular docking, and anticancer evaluations. Archiv der Pharmazie 352 (12) (2019)

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Ibrahim H Eissa