Alec M DeSimone (Alec DeSimone)

Publication Activity (10 Years)

Years Active: 2019-2023
Publications (10 Years): 7

Top Topics

Autism Spectrum Disorder

Muscular Dystrophy

Hyaluronic Acid

Top Venues

Research square

Science advances

Disease models & mechanisms

Cell death & disease

This page only lists publications with an associated author ORCID identifier.

Publications

Justin Cohen, Shushu Huang, Katherine Koczwara, Vincent Ho, Keryn Woodman, Angela Lek, Jack L Arbiser, Monkol Lek, Alec M DeSimone
Flavones provide resistance to DUX4-induced toxicity via an mTor-independent mechanism. Research square (2023)
Justin Cohen, Shushu Huang, Katherine E Koczwara, Kristen T Woods, Vincent Ho, Keryn G Woodman, Jack L Arbiser, Katelyn Daman, Monkol Lek, Charles P Emerson, Alec M DeSimone
Flavones provide resistance to DUX4-induced toxicity via an mTor-independent mechanism. Cell death & disease 14 (11) (2023)
Justin Cohen, Shushu Huang, Katherine Koczwara, Vincent Ho, Keryn Woodman, Angela Lek, Jack L Arbiser, Monkol Lek, Alec M DeSimone
Flavones provide resistance to DUX4-induced toxicity via an mTor-independent mechanism. Research square (2023)
Justin Cohen, Shushu Huang, Katherine Koczwara, Vincent Ho, Keryn Woodman, Angela Lek, Jack L Arbiser, Monkol Lek, Alec M DeSimone
Flavones provide resistance to DUX4-induced toxicity via an mTor-independent mechanism. Research square (2023)
Angela Lek, Yuanfan Zhang, Keryn G Woodman, Shushu Huang, Alec M DeSimone, Justin Cohen, Vincent Ho, James Conner, Lillian Mead, Andrew Kodani, Anna Pakula, Neville E Sanjana, Oliver D King, Peter L Jones, Kathryn R Wagner, Monkol Lek, Louis M Kunkel
Applying genome-wide CRISPR-Cas9 screens for therapeutic discovery in facioscapulohumeral muscular dystrophy. Science translational medicine 12 (536) (2021)
Alec M DeSimone, Justin Cohen, Monkol Lek, Angela Lek
Cellular and animal models for facioscapulohumeral muscular dystrophy. Disease models & mechanisms 13 (10) (2020)
Alec M DeSimone, John Leszyk, Kathryn Wagner, Charles P Emerson
Identification of the hyaluronic acid pathway as a therapeutic target for facioscapulohumeral muscular dystrophy. Science advances 5 (12) (2019)