Alemayehu Abebe Gorfe (Alemayehu Gorfe, Alemayehu A Gorfe, Alemayehu G Abebe)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 36

Top Venues

The journal of physical chemistry. B

Journal of the American Chemical Society

Chembiochem : a European journal of chemical biology

ACS bio & med chem Au

The University of Texas Health Science Center at Houston

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The University of Texas Health Science Center at Houston Jan 01 2009

United States

Associate Professor :: Integrative Biology and Pharmacology

Publications

Cynthia V Pagba, Amit K Gupta, Kasuni Dilsha, Parisa Sadrpour, Jacob Jakubec, Priyanka Prakash, Dharini van der Hoeven, Kwang-Jin Cho, Scott Gilbertson, Alemayehu Abebe Gorfe
Biophysical and Biochemical Characterization of Structurally Diverse Small Molecule Hits for KRAS Inhibition. Chembiochem : a European journal of chemical biology (2024)
Chase M Hutchins, Alemayehu Abebe Gorfe
Intrinsically Disordered Membrane Anchors of Rheb, RhoA, and DiRas3 Small GTPases: Molecular Dynamics, Membrane Organization, and Interactions. The journal of physical chemistry. B 128 (27) (2024)
Mussie K Araya, Wei Chen, Yuepeng Ke, Yubin Zhou, Alemayehu Abebe Gorfe, John F Hancock, Junchen Liu
Differential Lipid Binding Specificities of RAP1A and RAP1B are Encoded by the Amino Acid Sequence of the Membrane Anchors. Journal of the American Chemical Society (2024)
Mussie K Araya, Wei Chen, Yuepeng Ke, Yubin Zhou, Alemayehu Abebe Gorfe, John F Hancock, Junchen Liu
Differential Lipid Binding Specificities of RAP1A and RAP1B are Encoded by the Amino Acid Sequence of the Membrane Anchors. Journal of the American Chemical Society (2024)
Cynthia V Pagba, Amit K Gupta, Kasuni Dilsha, Parisa Sadrpour, Jacob Jakubec, Priyanka Prakash, Dharini van der Hoeven, Kwang-Jin Cho, Scott Gilbertson, Alemayehu Abebe Gorfe
Biophysical and Biochemical Characterization of Structurally Diverse Small Molecule Hits for KRAS Inhibition. Chembiochem : a European journal of chemical biology 25 (7) (2024)
Chase M Hutchins, Alemayehu Abebe Gorfe
Intrinsically Disordered Membrane Anchors of Rheb, RhoA, and DiRas3 Small GTPases: Molecular Dynamics, Membrane Organization, and Interactions. The journal of physical chemistry. B (2024)
Wei Ruan, Tao Li, Jaewoong Lee, In Hyuk Bang, Wankun Deng, Xinxin Ma, Seung-Hee Yoo, Boyun Kim, Jiwen Li, Xiaoyi Yuan, Yu A An, Yin-Ying Wang, Yafen Liang, Matthew Deberge, Dongze Zhang, Zhen Zhou, Yanyu Wang, Joshua M Gorham, Jonathan G Seidman, Christine E Seidman, Sary F Aranki, Ragini Nair, Lei Li, Jagat Narula, Zhong-Ming Zhao, Alemayehu Abebe Gorfe, Jochen Daniel Muehlschlegel, Kuang-Lei Tsai, Holger K Eltzschig
The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury. Research square (2024)
Mussie K Araya, Wei Chen, Yuepeng Ke, Yubin Zhou, Alemayehu Abebe Gorfe, John F Hancock, Junchen Liu
Differential Lipid Binding Specificities of RAP1A and RAP1B are Encoded by the Amino Acid Sequence of the Membrane Anchors. Journal of the American Chemical Society 146 (29) (2024)
Chase M Hutchins, Alemayehu Abebe Gorfe
Intrinsically Disordered Membrane Anchors of Rheb, RhoA, and DiRas3 Small GTPases: Molecular Dynamics, Membrane Organization, and Interactions. The journal of physical chemistry. B 128 (27) (2024)
Cynthia V Pagba, Amit K Gupta, Kasuni Dilsha, Parisa Sadrpour, Jacob Jakubec, Priyanka Prakash, Dharini van der Hoeven, Kwang-Jin Cho, Scott Gilbertson, Alemayehu Abebe Gorfe
Biophysical and Biochemical Characterization of Structurally Diverse Small Molecule Hits for KRAS Inhibition. Chembiochem : a European journal of chemical biology 25 (7) (2024)
Mussie K Araya, Wei Chen, Yuepeng Ke, Yubin Zhou, Alemayehu Abebe Gorfe, John F Hancock, Junchen Liu
Differential Lipid Binding Specificities of RAP1A and RAP1B are Encoded by the Amino Acid Sequence of the Membrane Anchors. Journal of the American Chemical Society 146 (29) (2024)
Chase M Hutchins, Alemayehu Abebe Gorfe
Intrinsically Disordered Membrane Anchors of Rheb, RhoA, and DiRas3 Small GTPases: Molecular Dynamics, Membrane Organization, and Interactions. The journal of physical chemistry. B 128 (27) (2024)
Chase M Hutchins, Alemayehu Abebe Gorfe
Intrinsically Disordered Membrane Anchors of Rheb, RhoA, and DiRas3 Small GTPases: Molecular Dynamics, Membrane Organization, and Interactions. The journal of physical chemistry. B 128 (27) (2024)
Mussie K Araya, Wei Chen, Yuepeng Ke, Yubin Zhou, Alemayehu Abebe Gorfe, John F Hancock, Junchen Liu
Differential Lipid Binding Specificities of RAP1A and RAP1B are Encoded by the Amino Acid Sequence of the Membrane Anchors. Journal of the American Chemical Society 146 (29) (2024)
Chase M Hutchins, Alemayehu Abebe Gorfe
Intrinsically Disordered Membrane Anchors of Rheb, RhoA, and DiRas3 Small GTPases: Molecular Dynamics, Membrane Organization, and Interactions. The journal of physical chemistry. B (2024)
Holger K Eltzschig, Wei Ruan, Tao Li, Jaewoong Lee, In Hyuk Bang, Wankun Deng, Xinxin Ma, Seung-Hee Yoo, Boyun Kim, Jiwen Li, Xiaoyi Yuan, Yu An, Yin-Ying Wang, Yafen Liang, Matthew Deberge, Dongze Zhang, Zhen Zhou, Yanyu Wang, Joshua M Gorham, Jonathan G Seidman, Christine E Seidman, Sary Aranki, Ragini Nair, Lei Li, Jagat Narula, Zhong-Ming Zhao, Alemayehu Abebe Gorfe, Jochen Muehlschlegel, Kuang-Lei Tsai
The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury. Research square (2024)
Chase M Hutchins, Alemayehu Abebe Gorfe
Intrinsically Disordered Membrane Anchors of Rheb, RhoA, and DiRas3 Small GTPases: Molecular Dynamics, Membrane Organization, and Interactions. The journal of physical chemistry. B 128 (27) (2024)
Mussie K Araya, Wei Chen, Yuepeng Ke, Yubin Zhou, Alemayehu Abebe Gorfe, John F Hancock, Junchen Liu
Differential Lipid Binding Specificities of RAP1A and RAP1B are Encoded by the Amino Acid Sequence of the Membrane Anchors. Journal of the American Chemical Society 146 (29) (2024)
Mussie K Araya, Alemayehu Abebe Gorfe
Conformational ensemble-dependent lipid recognition and segregation by prenylated intrinsically disordered regions in small GTPases. Communications biology 6 (1) (2023)
Cynthia V Pagba, Amit K Gupta, Alemayehu Abebe Gorfe
Small-Molecule Inhibition of KRAS through Conformational Selection. ACS omega 8 (34) (2023)
Mussie K Araya, Alemayehu Abebe Gorfe
Phosphatidylserine and Phosphatidylethanolamine Asymmetry Have a Negligible Effect on the Global Structure, Dynamics, and Interactions of the KRAS Lipid Anchor. The journal of physical chemistry. B 126 (24) (2022)
Cynthia V Pagba, Amit K Gupta, Ali K Naji, Dharini van der Hoeven, Kelly Churion, Xiaowen Liang, Jacob Jakubec, Magnus Hook, Yan Zuo, Marisela Martinez de Kraatz, Jeffrey A Frost, Alemayehu Abebe Gorfe
KRAS Inhibitor that Simultaneously Inhibits Nucleotide Exchange Activity and Effector Engagement. ACS bio & med chem Au 2 (6) (2022)
Cynthia V Pagba, Amit K Gupta, Ali K Naji, Dharini van der Hoeven, Kelly Churion, Xiaowen Liang, Jacob Jakubec, Magnus Hook, Yan Zuo, Marisela Martinez de Kraatz, Jeffrey A Frost, Alemayehu Abebe Gorfe
KRAS Inhibitor that Simultaneously Inhibits Nucleotide Exchange Activity and Effector Engagement. ACS bio & med chem Au 2 (6) (2022)
Xubo Lin, Alemayehu Abebe Gorfe
Transmembrane potential of physiologically relevant model membranes: Effects of membrane asymmetry. The Journal of chemical physics 153 (10) (2021)
Priyanka Prakash, Alemayehu Abebe Gorfe
Determinants of Membrane Orientation Dynamics in Lipid-Modified Small GTPases. JACS Au 2 (1) (2021)
Yong Zhou, Priyanka S Prakash, Hong Liang, Alemayehu Abebe Gorfe, John F Hancock
The KRAS and other prenylated polybasic domain membrane anchors recognize phosphatidylserine acyl chain structure. Proceedings of the National Academy of Sciences of the United States of America 118 (6) (2021)
Vinay V Nair, Guowei Yin, Jerry Zhang, John F Hancock, Sharon L Campbell, Alemayehu Abebe Gorfe
Monoubiquitination of KRAS at Lysine104 and Lysine147 Modulates Its Dynamics and Interaction with Partner Proteins. The journal of physical chemistry. B 125 (18) (2021)
John F Hancock, Alemayehu Abebe Gorfe
Building insights into KRAS signaling complexes. Nature structural & molecular biology 28 (10) (2021)
Daniel Kwaku Abankwa, Alemayehu Abebe Gorfe
Mechanisms of Ras Membrane Organization and Signaling: Ras Rocks Again. Biomolecules 10 (11) (2020)
Shuo Lu, Zhenlong Li, Alemayehu Abebe Gorfe, Lei Zheng
Intracellular Ca2+ regulation of H+/Ca2+ antiporter YfkE mediated by a Ca2+ mini-sensor. Proceedings of the National Academy of Sciences of the United States of America 117 (19) (2020)
Shun Ying Quah, Michelle Siying Tan, Kok Lian Ho, Nizar Abdul Manan, Alemayehu Abebe Gorfe, Pran Kishore Deb, Sreenivasa Rao Sagineedu, Johnson Stanslas
In silico and saturation transfer difference NMR approaches to unravel the binding mode of an andrographolide derivative to K-Ras oncoprotein. Future medicinal chemistry 12 (18) (2020)
Priyanka Prakash, Alemayehu Abebe Gorfe
Probing the Conformational and Energy Landscapes of KRAS Membrane Orientation. The journal of physical chemistry. B 123 (41) (2019)
Xubo Lin, Alemayehu Abebe Gorfe
Understanding Membrane Domain-Partitioning Thermodynamics of Transmembrane Domains with Potential of Mean Force Calculations. The journal of physical chemistry. B 123 (5) (2019)
Mohammed Khaled, Alemayehu Abebe Gorfe, Abdallah Sayyed-Ahmad
Conformational and Dynamical Effects of Tyr32 Phosphorylation in K-Ras: Molecular Dynamics Simulation and Markov State Models Analysis. The journal of physical chemistry. B 123 (36) (2019)
Suparna Sarkar-Banerjee, Abdallah Sayyed-Ahmad, Priyanka Prakash, Kwang-Jin Cho, Melvin Neal Waxham, John F Hancock, Alemayehu Abebe Gorfe
Spatiotemporal Analysis of K-Ras Plasma Membrane Interactions Reveals Multiple High Order Homo-oligomeric Complexes. Journal of the American Chemical Society 139 (38) (2017)
Abdallah Sayyed-Ahmad, Alemayehu Abebe Gorfe
Mixed-Probe Simulation and Probe-Derived Surface Topography Map Analysis for Ligand Binding Site Identification. Journal of chemical theory and computation 13 (4) (2017)

Alemayehu Abebe Gorfe.css-eqlu8i{font-size:small;padding-left:4px;} (Alemayehu Gorfe, Alemayehu A Gorfe, Alemayehu G Abebe)

Publication Activity (10 Years)

Top Topics

Top Venues

Alemayehu Abebe Gorfe (Alemayehu Gorfe, Alemayehu A Gorfe, Alemayehu G Abebe)