Alexandre Houy

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 23

Top Topics

Advanced Non Small Cell Lung Cancer

Histone Deacetylase

Gene Expression

Top Venues

Science immunology

The Journal of experimental medicine

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

David Rombaut, Carine Lefèvre, Tony Rached, Sabrina Bondu, Anne Letessier, Raphaël M Mangione, Batoul Farhat, Auriane Lesieur-Pasquier, Daisy Castillo-Guzman, Ismael Boussaid, Chloé Friedrich, Aurore Tourville, Magali De Carvalho, Francoise Levavasseur, Marjorie Leduc, Morgane Le-Gall, Sarah Battault, Marie Temple, Alexandre Houy, Didier Bouscary, Lise Willems, Sophie Park, Sophie Raynaud, Thomas Cluzeau, Emmanuelle Clappier, Pierre Fenaux, Lionel Ades, Raphaël Margueron, Michel Wassef, Samar Alsafadi, Nicolas Chapuis, Olivier Kosmider, Eric Solary, Angelos Constantinou, Marc-Henri Stern, Nathalie M Droin, Benoit Palancade, Benoit Miotto, Frédéric Chedin, Michaela Fontenay
Accelerated DNA replication fork speed due to loss of R-loops in myelodysplastic syndromes with SF3B1 mutation. Nature communications 15 (1) (2024)
David Rombaut, Carine Lefèvre, Tony Rached, Sabrina Bondu, Anne Letessier, Raphaël M Mangione, Batoul Farhat, Auriane Lesieur-Pasquier, Daisy Castillo-Guzman, Ismael Boussaid, Chloé Friedrich, Aurore Tourville, Magali De Carvalho, Francoise Levavasseur, Marjorie Leduc, Morgane Le-Gall, Sarah Battault, Marie Temple, Alexandre Houy, Didier Bouscary, Lise Willems, Sophie Park, Sophie Raynaud, Thomas Cluzeau, Emmanuelle Clappier, Pierre Fenaux, Lionel Ades, Raphaël Margueron, Michel Wassef, Samar Alsafadi, Nicolas Chapuis, Olivier Kosmider, Eric Solary, Angelos Constantinou, Marc-Henri Stern, Nathalie M Droin, Benoit Palancade, Benoit Miotto, Frédéric Chedin, Michaela Fontenay
Accelerated DNA replication fork speed due to loss of R-loops in myelodysplastic syndromes with SF3B1 mutation. Nature communications 15 (1) (2024)
Francesca Lucibello, Ana Ines Lalanne, Anne-Laure Le Gac, Abdoulaye Soumare, Setareh Aflaki, Joanna Cyrta, Lea Dubreuil, Martin Mestdagh, Marion Salou, Alexandre Houy, Christina Ekwegbara, Camille Jamet, Sophie Gardrat, Anais Le Ven, Karine Bernardeau, Nathalie Cassoux, Alexandre Matet, Denis Malaise, Gaëlle Pierron, Sophie Piperno-Neumann, Marc-Henri Stern, Manuel J Rodrigues, Olivier Lantz
Divergent local and systemic antitumor response in primary uveal melanomas. The Journal of experimental medicine 221 (6) (2024)
Francesca Lucibello, Ana Ines Lalanne, Anne-Laure Le Gac, Abdoulaye Soumare, Setareh Aflaki, Joanna Cyrta, Lea Dubreuil, Martin Mestdagh, Marion Salou, Alexandre Houy, Christina Ekwegbara, Camille Jamet, Sophie Gardrat, Anais Le Ven, Karine Bernardeau, Nathalie Cassoux, Alexandre Matet, Denis Malaise, Gaëlle Pierron, Sophie Piperno-Neumann, Marc-Henri Stern, Manuel J Rodrigues, Olivier Lantz
Divergent local and systemic antitumor response in primary uveal melanomas. The Journal of experimental medicine 221 (6) (2024)
Francesca Lucibello, Ana Ines Lalanne, Anne-Laure Le Gac, Abdoulaye Soumare, Setareh Aflaki, Joanna Cyrta, Lea Dubreuil, Martin Mestdagh, Marion Salou, Alexandre Houy, Christina Ekwegbara, Camille Jamet, Sophie Gardrat, Anais Le Ven, Karine Bernardeau, Nathalie Cassoux, Alexandre Matet, Denis Malaise, Gaëlle Pierron, Sophie Piperno-Neumann, Marc-Henri Stern, Manuel J Rodrigues, Olivier Lantz
Divergent local and systemic antitumor response in primary uveal melanomas. The Journal of experimental medicine 221 (6) (2024)
Francesca Lucibello, Ana Ines Lalanne, Anne-Laure Le Gac, Abdoulaye Soumare, Setareh Aflaki, Joanna Cyrta, Lea Dubreuil, Martin Mestdagh, Marion Salou, Alexandre Houy, Christina Ekwegbara, Camille Jamet, Sophie Gardrat, Anais Le Ven, Karine Bernardeau, Nathalie Cassoux, Alexandre Matet, Denis Malaise, Gaëlle Pierron, Sophie Piperno-Neumann, Marc-Henri Stern, Manuel J Rodrigues, Olivier Lantz
Divergent local and systemic antitumor response in primary uveal melanomas. The Journal of experimental medicine 221 (6) (2024)
David Rombaut, Carine Lefèvre, Tony Rached, Sabrina Bondu, Anne Letessier, Raphaël M Mangione, Batoul Farhat, Auriane Lesieur-Pasquier, Daisy Castillo-Guzman, Ismael Boussaid, Chloé Friedrich, Aurore Tourville, Magali De Carvalho, Francoise Levavasseur, Marjorie Leduc, Morgane Le-Gall, Sarah Battault, Marie Temple, Alexandre Houy, Didier Bouscary, Lise Willems, Sophie Park, Sophie Raynaud, Thomas Cluzeau, Emmanuelle Clappier, Pierre Fenaux, Lionel Ades, Raphaël Margueron, Michel Wassef, Samar Alsafadi, Nicolas Chapuis, Olivier Kosmider, Eric Solary, Angelos Constantinou, Marc-Henri Stern, Nathalie M Droin, Benoit Palancade, Benoit Miotto, Frédéric Chedin, Michaela Fontenay
Accelerated DNA replication fork speed due to loss of R-loops in myelodysplastic syndromes with SF3B1 mutation. Nature communications 15 (1) (2024)
Antonela Merlotti, Benjamin Sadacca, Yago A Arribas, Mercia Ngoma, Marianne Burbage, Christel Goudot, Alexandre Houy, Ares Rocañín-Arjó, Ana Ines Lalanne, Agathe Seguin-Givelet, Marine Lefevre, Sandrine Heurtebise-Chrétien, Blandine Baudon, Giacomo Oliveira, Damarys Loew, Montserrat Carrascal, Catherine J Wu, Olivier Lantz, Marc-Henri Stern, Nicolas Girard, Joshua J Waterfall, Sebastian Amigorena
Noncanonical splicing junctions between exons and transposable elements represent a source of immunogenic recurrent neo-antigens in patients with lung cancer. Science immunology 8 (80) (2023)
Marianne Burbage, Ares Rocañín-Arjó, Blandine Baudon, Yago A Arribas, Antonela Merlotti, Derek C Rookhuizen, Sandrine Heurtebise-Chrétien, Mengliang Ye, Alexandre Houy, Nina Burgdorf, Guadalupe Suarez, Marine Gros, Benjamin Sadacca, Montserrat Carrascal, Andrea Garmilla, Mylène Bohec, Sylvain Baulande, Berangere Lombard, Damarys Loew, Joshua J Waterfall, Marc-Henri Stern, Christel Goudot, Sebastian Amigorena
Epigenetically controlled tumor antigens derived from splice junctions between exons and transposable elements. Science immunology 8 (80) (2023)
Antonela Merlotti, Benjamin Sadacca, Yago A Arribas, Mercia Ngoma, Marianne Burbage, Christel Goudot, Alexandre Houy, Ares Rocañín-Arjó, Ana Ines Lalanne, Agathe Seguin-Givelet, Marine Lefevre, Sandrine Heurtebise-Chrétien, Blandine Baudon, Giacomo Oliveira, Damarys Loew, Montserrat Carrascal, Catherine J Wu, Olivier Lantz, Marc-Henri Stern, Nicolas Girard, Joshua J Waterfall, Sebastian Amigorena
Noncanonical splicing junctions between exons and transposable elements represent a source of immunogenic recurrent neo-antigens in patients with lung cancer. Science immunology 8 (80) (2023)
Antonela Merlotti, Benjamin Sadacca, Yago A Arribas, Mercia Ngoma, Marianne Burbage, Christel Goudot, Alexandre Houy, Ares Rocañín-Arjó, Ana Ines Lalanne, Agathe Seguin-Givelet, Marine Lefevre, Sandrine Heurtebise-Chrétien, Blandine Baudon, Giacomo Oliveira, Damarys Loew, Montserrat Carrascal, Catherine J Wu, Olivier Lantz, Marc-Henri Stern, Nicolas Girard, Joshua J Waterfall, Sebastian Amigorena
Noncanonical splicing junctions between exons and transposable elements represent a source of immunogenic recurrent neo-antigens in patients with lung cancer. Science immunology 8 (80) (2023)
Philip Bland, Harry Saville, Patty T Wai, Lucinda Curnow, Gareth Muirhead, Jadwiga Nieminuszczy, Nivedita Ravindran, Marie Beatrix John, Somaieh Hedayat, Holly E Barker, James Wright, Lu Yu, Ioanna Mavrommati, Abigail Read, Barrie Peck, Mark Allen, Patrycja Gazinska, Helen N Pemberton, Aditi Gulati, Sarah Nash, Farzana Noor, Naomi Guppy, Ioannis Roxanis, Guy Pratt, Ceri E Oldreive, Tatjana Stankovic, Samantha Barlow, Helen Kalirai, Sarah E Coupland, Ronan Broderick, Samar Alsafadi, Alexandre Houy, Marc-Henri Stern, Stephen J Pettitt, Jyoti Sharma Choudhary, Syed Haider, Wojciech Niedzwiedz, Christopher J Lord, Rachael Natrajan
SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response. Nature genetics (2023)
Marianne Burbage, Ares Rocañín-Arjó, Blandine Baudon, Yago A Arribas, Antonela Merlotti, Derek C Rookhuizen, Sandrine Heurtebise-Chrétien, Mengliang Ye, Alexandre Houy, Nina Burgdorf, Guadalupe Suarez, Marine Gros, Benjamin Sadacca, Montserrat Carrascal, Andrea Garmilla, Mylène Bohec, Sylvain Baulande, Berangere Lombard, Damarys Loew, Joshua J Waterfall, Marc-Henri Stern, Christel Goudot, Sebastian Amigorena
Epigenetically controlled tumor antigens derived from splice junctions between exons and transposable elements. Science immunology 8 (80) (2023)
Antonela Merlotti, Benjamin Sadacca, Yago A Arribas, Mercia Ngoma, Marianne Burbage, Christel Goudot, Alexandre Houy, Ares Rocañín-Arjó, Ana Ines Lalanne, Agathe Seguin-Givelet, Marine Lefevre, Sandrine Heurtebise-Chrétien, Blandine Baudon, Giacomo Oliveira, Damarys Loew, Montserrat Carrascal, Catherine J Wu, Olivier Lantz, Marc-Henri Stern, Nicolas Girard, Joshua J Waterfall, Sebastian Amigorena
Noncanonical splicing junctions between exons and transposable elements represent a source of immunogenic recurrent neo-antigens in patients with lung cancer. Science immunology 8 (80) (2023)
Marianne Burbage, Ares Rocañín-Arjó, Blandine Baudon, Yago A Arribas, Antonela Merlotti, Derek C Rookhuizen, Sandrine Heurtebise-Chrétien, Mengliang Ye, Alexandre Houy, Nina Burgdorf, Guadalupe Suarez, Marine Gros, Benjamin Sadacca, Montserrat Carrascal, Andrea Garmilla, Mylène Bohec, Sylvain Baulande, Berangere Lombard, Damarys Loew, Joshua J Waterfall, Marc-Henri Stern, Christel Goudot, Sebastian Amigorena
Epigenetically controlled tumor antigens derived from splice junctions between exons and transposable elements. Science immunology 8 (80) (2023)
Marianne Burbage, Ares Rocañín-Arjó, Blandine Baudon, Yago A Arribas, Antonela Merlotti, Derek C Rookhuizen, Sandrine Heurtebise-Chrétien, Mengliang Ye, Alexandre Houy, Nina Burgdorf, Guadalupe Suarez, Marine Gros, Benjamin Sadacca, Montserrat Carrascal, Andrea Garmilla, Mylène Bohec, Sylvain Baulande, Berangere Lombard, Damarys Loew, Joshua J Waterfall, Marc-Henri Stern, Christel Goudot, Sebastian Amigorena
Epigenetically controlled tumor antigens derived from splice junctions between exons and transposable elements. Science immunology 8 (80) (2023)
Raquel Vivet-Noguer, Malcy Tarin, Christine Canbezdi, Stephane Dayot, Lisseth Silva, Alexandre Houy, Sylvain Martineau, Virginie Mieulet, Geraldine Gentric, Damarys Loew, Bérangère Lombard, Fariba Nemati, Sophie Richon, Lea Guyonnet, Vincent Servois, Stéphan Vagner, Marc-Henri Stern, Sergio Roman-Roman, Samar Alsafadi
Glycolysis Dependency as a Hallmark of SF3B1 -Mutated Cells. Cancers 14 (9) (2022)
Jeremy Bigot, Ana I Lalanne, Francesca Lucibello, Paul Gueguen, Alexandre Houy, Stephane Dayot, Olivier Ganier, Jules Gilet, Jimena Tosello, Fariba Nemati, Gaëlle Pierron, Joshua J Waterfall, Raymond L Barnhill, Sophie Gardrat, Sophie Piperno-Neumann, Tatiana Popova, Vanessa Masson, Damarys Loew, Pascale Mariani, Nathalie Cassoux, Sebastian Amigorena, Manuel J Rodrigues, Samar Alsafadi, Marc-Henri Stern, Olivier Lantz
Splicing Patterns in SF3B1-Mutated Uveal Melanoma Generate Shared Immunogenic Tumor-Specific Neoepitopes. Cancer discovery 11 (8) (2021)
Sophie Gardrat, Alexandre Houy, Kelly Brooks, Nathalie Cassoux, Raymond Barnhill, Stéphane Dayot, Ivan Bièche, Virginie Raynal, Sylvain Baulande, Richard Marais, Sergio Roman-Roman, Marc-Henri Stern, Manuel J Rodrigues
Definition of Biologically Distinct Groups of Conjunctival Melanomas According to Etiological Factors and Implications for Precision Medicine. Cancers 13 (15) (2021)
Sabrina Bondu, Anne-Sophie Alary, Carine Lefèvre, Alexandre Houy, Grace C-L Jung, Thibaud Lefèbvre, David Rombaut, Ismael Boussaid, Abderrahmane Bousta, François Guillonneau, Prunelle Perrier, Samar Alsafadi, Michel Wassef, Raphaël Margueron, Alice Rousseau, Nathalie M Droin, Nicolas Cagnard, Sophie Kaltenbach, Susann Winter, Anne-Sophie Kubasch, Didier Bouscary, Valeria Santini, Andrea Toma, Mathilde Hunault, Aspasia Stamatoullas, Emmanuel Gyan, Thomas Cluzeau, Uwe Platzbecker, Lionel Ades, Hervé Puy, Marc-Henri Stern, Zoubida Karim, Patrick Mayeux, Elizabeta Nemeth, Sophie Park, Tomas Ganz, Léon Kautz, Olivier Kosmider, Michaela Fontenay
A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome. Science translational medicine 11 (500) (2020)
Samar Alsafadi, Stephane Dayot, Malcy Tarin, Alexandre Houy, Dorine Bellanger, Michele Cornella, Michel Wassef, Joshua J Waterfall, Erik Lehnert, Sergio Roman-Roman, Marc-Henri Stern, Tatiana Popova
Genetic alterations of SUGP1 mimic mutant-SF3B1 splice pattern in lung adenocarcinoma and other cancers. Oncogene 40 (1) (2020)
Petros K Tsantoulis, Mauro Delorenzi, Ivan Bièche, Sophie Vacher, Pascale Mariani, Nathalie Cassoux, Alexandre Houy, Marc-Henri Stern, Sergio Roman-Roman, Pierre-Yves Dietrich, Arnaud Roth, Wulfran Cacheux
Prospective validation in epithelial tumors of a gene expression predictor of liver metastasis derived from uveal melanoma. Scientific reports 9 (1) (2019)
Manuel Rodrigues, Lenha Mobuchon, Alexandre Houy, Samar Alsafadi, Sylvain Baulande, Odette Mariani, Benjamin Marande, Khadija Ait Rais, Monique K Van der Kooij, Ellen H W Kapiteijn, Sieta Gassama, Sophie Gardrat, Raymond L Barnhill, Vincent Servois, Rémi Dendale, Marc Putterman, Sarah Tick, Sophie Piperno-Neumann, Nathalie Cassoux, Gaëlle Pierron, Joshua J Waterfall, Sergio Roman-Roman, Marc-Henri Stern
Evolutionary Routes in Metastatic Uveal Melanomas Depend on MBD4 Alterations. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (18) (2019)