Alysson Renato Muotri (Alysson R Muotri, A R Muotri)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 51

Top Topics

Autism Spectrum Disorder

Top Venues

Molecular psychiatry

Nature protocols

Science (New York, N.Y.)

Genetics and molecular biology

This page only lists publications with an associated author ORCID identifier.

Publications

Michael Q Fitzgerald, Tiffany Chu, Francesca Puppo, Rebeca Blanch, Miguel Chillón, Shankar Subramaniam, Alysson Renato Muotri
Generation of 'semi-guided' cortical organoids with complex neural oscillations. Nature protocols (2024)
Michael Q Fitzgerald, Tiffany Chu, Francesca Puppo, Rebeca Blanch, Miguel Chillón, Shankar Subramaniam, Alysson Renato Muotri
Generation of 'semi-guided' cortical organoids with complex neural oscillations. Nature protocols (2024)
Michael Q Fitzgerald, Tiffany Chu, Francesca Puppo, Rebeca Blanch, Miguel Chillón, Shankar Subramaniam, Alysson Renato Muotri
Generation of 'semi-guided' cortical organoids with complex neural oscillations. Nature protocols (2024)
Hyeon-Yeol Cho, Myungsik Yoo, Thanapat Pongkulapa, Hudifah Rabie, Alysson Renato Muotri, Perry T Yin, Jeong-Woo Choi, Ki-Bum Lee
Magnetic Nanoparticle-Assisted Non-Viral CRISPR-Cas9 for Enhanced Genome Editing to Treat Rett Syndrome. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (24) (2024)
Michael Q Fitzgerald, Tiffany Chu, Francesca Puppo, Rebeca Blanch, Miguel Chillón, Shankar Subramaniam, Alysson Renato Muotri
Generation of 'semi-guided' cortical organoids with complex neural oscillations. Nature protocols (2024)
Hyeon-Yeol Cho, Myungsik Yoo, Thanapat Pongkulapa, Hudifah Rabie, Alysson Renato Muotri, Perry T Yin, Jeong-Woo Choi, Ki-Bum Lee
Magnetic Nanoparticle-Assisted Non-Viral CRISPR-Cas9 for Enhanced Genome Editing to Treat Rett Syndrome. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2024)
Hyeon-Yeol Cho, Myungsik Yoo, Thanapat Pongkulapa, Hudifah Rabie, Alysson Renato Muotri, Perry T Yin, Jeong-Woo Choi, Ki-Bum Lee
Magnetic Nanoparticle-Assisted Non-Viral CRISPR-Cas9 for Enhanced Genome Editing to Treat Rett Syndrome. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (24) (2024)
Michael Q Fitzgerald, Tiffany Chu, Francesca Puppo, Rebeca Blanch, Miguel Chillón, Shankar Subramaniam, Alysson Renato Muotri
Generation of 'semi-guided' cortical organoids with complex neural oscillations. Nature protocols (2024)
Michael Q Fitzgerald, Tiffany Chu, Francesca Puppo, Rebeca Blanch, Miguel Chillón, Shankar Subramaniam, Alysson Renato Muotri
Generation of 'semi-guided' cortical organoids with complex neural oscillations. Nature protocols (2024)
Roberto Hirochi Herai, Katerina Semendeferi, Alysson Renato Muotri
Comment on "Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals". Science (New York, N.Y.) 379 (6636) (2023)
Alysson Renato Muotri
Interchromosomal translocation in neural progenitor cells exposed to L1 retrotransposition. Genetics and molecular biology 46 (1) (2023)
Gabriela Goldberg, Luisa Coelho, Guoya Mo, Laura A Adang, Meenakshi Patne, Zhoutao Chen, Ivan Garcia-Bassets, Pinar Mesci, Alysson Renato Muotri
TREX1 is required for microglial cholesterol homeostasis and oligodendrocyte terminal differentiation in human neural assembloids. Molecular psychiatry 29 (3) (2023)
Gabriela Goldberg, Luisa Coelho, Guoya Mo, Laura A Adang, Meenakshi Patne, Zhoutao Chen, Ivan Garcia-Bassets, Pinar Mesci, Alysson Renato Muotri
TREX1 is required for microglial cholesterol homeostasis and oligodendrocyte terminal differentiation in human neural assembloids. Molecular psychiatry (2023)
Gabriela Goldberg, Luisa Coelho, Guoya Mo, Laura A Adang, Meenakshi Patne, Zhoutao Chen, Ivan Garcia-Bassets, Pinar Mesci, Alysson Renato Muotri
TREX1 is required for microglial cholesterol homeostasis and oligodendrocyte terminal differentiation in human neural assembloids. Molecular psychiatry 29 (3) (2023)
Alysson Renato Muotri
Interchromosomal translocation in neural progenitor cells exposed to L1 retrotransposition. Genetics and molecular biology 46 (1) (2023)
Gabriela Goldberg, Luisa Coelho, Guoya Mo, Laura A Adang, Meenakshi Patne, Zhoutao Chen, Ivan Garcia-Bassets, Pinar Mesci, Alysson Renato Muotri
TREX1 is required for microglial cholesterol homeostasis and oligodendrocyte terminal differentiation in human neural assembloids. Molecular psychiatry (2023)
Gabriela Goldberg, Luisa Coelho, Guoya Mo, Laura A Adang, Meenakshi Patne, Zhoutao Chen, Ivan Garcia-Bassets, Pinar Mesci, Alysson Renato Muotri
TREX1 is required for microglial cholesterol homeostasis and oligodendrocyte terminal differentiation in human neural assembloids. Molecular psychiatry 29 (3) (2023)
Gabriela Goldberg, Luisa Coelho, Guoya Mo, Laura A Adang, Meenakshi Patne, Zhoutao Chen, Ivan Garcia-Bassets, Pinar Mesci, Alysson Renato Muotri
TREX1 is required for microglial cholesterol homeostasis and oligodendrocyte terminal differentiation in human neural assembloids. Molecular psychiatry (2023)
Gabriela Goldberg, Luisa Coelho, Guoya Mo, Laura A Adang, Meenakshi Patne, Zhoutao Chen, Ivan Garcia-Bassets, Pinar Mesci, Alysson Renato Muotri
TREX1 is required for microglial cholesterol homeostasis and oligodendrocyte terminal differentiation in human neural assembloids. Molecular psychiatry 29 (3) (2023)
Alysson Renato Muotri
Brain Model Technology and Its Implications. Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees (2023)
Alysson Renato Muotri
Interchromosomal translocation in neural progenitor cells exposed to L1 retrotransposition. Genetics and molecular biology 46 (1) (2023)
Gabriela Goldberg, Luisa Coelho, Guoya Mo, Laura A Adang, Meenakshi Patne, Zhoutao Chen, Ivan Garcia-Bassets, Pinar Mesci, Alysson Renato Muotri
TREX1 is required for microglial cholesterol homeostasis and oligodendrocyte terminal differentiation in human neural assembloids. Molecular psychiatry 29 (3) (2023)
Roberto Hirochi Herai, Katerina Semendeferi, Alysson Renato Muotri
Comment on "Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals". Science (New York, N.Y.) 379 (6636) (2023)
Alysson Renato Muotri
Interchromosomal translocation in neural progenitor cells exposed to L1 retrotransposition. Genetics and molecular biology 46 (1) (2023)
Roberto Hirochi Herai, Katerina Semendeferi, Alysson Renato Muotri
Comment on "Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals". Science (New York, N.Y.) 379 (6636) (2023)
Rebecca S F Mok, Wenbo Zhang, Taimoor I Sheikh, Kartik Pradeepan, Isabella R Fernandes, Leah C DeJong, Gabriel Benigno, Matthew R Hildebrandt, Marat Mufteev, Deivid C Rodrigues, Wei Wei, Alina Piekna, Jiajie Liu, Alysson Renato Muotri, John B Vincent, Lyle E Muller, Julio C Martinez-Trujillo, Michael W Salter, James Ellis
Wide spectrum of neuronal and network phenotypes in human stem cell-derived excitatory neurons with Rett syndrome-associated MECP2 mutations. Translational psychiatry 12 (1) (2022)
Pinar Mesci, Janaina S de Souza, Laura Martin-Sancho, Angela Macia, Aurian Saleh, Xin Yin, Cedric Snethlage, Jason W Adams, Simoni H Avansini, Roberto H Herai, Angels Almenar-Queralt, Yuan Pu, Ryan A Szeto, Gabriela Goldberg, Patrick T Bruck, Fabio Papes, Sumit K Chanda, Alysson Renato Muotri
SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir. PLoS biology 20 (11) (2022)
Danny Antaki, James Guevara, Adam X Maihofer, Marieke Klein, Madhusudan Gujral, Jakob Grove, Caitlin E Carey, Oanh Hong, María Jesús Arranz, Amaia Hervas, Christina Corsello, Keith K Vaux, Alysson Renato Muotri, Lilia M Iakoucheva, Eric Courchesne, Karen Pierce, Joseph G Gleeson, Elise B Robinson, Caroline M Nievergelt, Jonathan Sebat
A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex. Nature genetics 54 (9) (2022)
Alysson Renato Muotri
"Archealization" of human brain organoids. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 47 (1) (2022)
Thomas Anthony Dixon, Alysson Renato Muotri
Advancing preclinical models of psychiatric disorders with human brain organoid cultures. Molecular psychiatry (2022)
Fabio Papes, Antonio Pedro Camargo, Janaina Sena de Souza, Vinicius M A Carvalho, Ryan A Szeto, Erin LaMontagne, José Ricardo Teixeira Júnior, Alysson R Muotri, Sandra M Sánchez-Sánchez, Thiago S Nakahara, Carolina N Santo, Wei Wu, Hang Yao, Barbara M P Araújo, Paulo Eduardo Neves Ferreira Velho, Gabriel G Haddad, Alysson Renato Muotri
Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content. Nature communications 13 (1) (2022)
Jason W Adams, Priscilla D Negraes, Justin Truong, Timothy Tran, Ryan A Szeto, Bruno S Guerra, Roberto Hirochi Herai, Carmen Teodorof-Diedrich, Stephen A Spector, Miguel Del Campo, Kenneth L Jones, Alysson Renato Muotri, Cleber A Trujillo
Impact of alcohol exposure on neural development and network formation in human cortical organoids. Molecular psychiatry (2022)
Jorge Urresti, Pan Zhang, Patricia Moran-Losada, Nam-Kyung Yu, Priscilla D Negraes, Cleber A Trujillo, Danny Antaki, Megha Amar, Kevin Chau, Akula Bala Pramod, Jolene Diedrich, Leon Tejwani, Sarah Romero, Jonathan Sebat, John Yates Iii, Alysson Renato Muotri, Lilia M Iakoucheva
Cortical organoids model early brain development disrupted by 16p11.2 copy number variants in autism. Molecular psychiatry (2021)
Priscilla D Negraes, Cleber A Trujillo, Nam-Kyung Yu, Wei Wu, Hang Yao, Nicholas Liang, Jonathan D Lautz, Ellius Kwok, Daniel B McClatchy, Jolene Diedrich, Salvador Martinez de Bartolome, Justin Truong, Ryan A Szeto, Timothy Tran, Roberto H Herai, Stephen E P Smith, Gabriel G Haddad, John Yates Iii, Alysson Renato Muotri
Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy. Molecular psychiatry (2021)
Ileana L Hanganu-Opatz, Simon J B Butt, Simon Hippenmeyer, Natalia V De Marco García, Jessica A Cardin, Bradley Voytek, Alysson Renato Muotri
The Logic of Developing Neocortical Circuits in Health and Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience 41 (5) (2021)
Tomohisa Kato, Alysson Renato Muotri
Mapping the hotspots for DNA repair synthesis in human brain organoids. Cell death and differentiation 28 (11) (2021)
Megha Amar, Akula Bala Pramod, Nam-Kyung Yu, Victor Munive Herrera, Lily R Qiu, Patricia Moran-Losada, Pan Zhang, Cleber A Trujillo, Jacob Ellegood, Jorge Urresti, Kevin Chau, Jolene Diedrich, Jiaye Chen, Jessica Gutierrez, Jonathan Sebat, Dhakshin Ramanathan, Jason P Lerch, John Yates Iii, Alysson Renato Muotri, Lilia M Iakoucheva
Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling. Molecular psychiatry 26 (7) (2021)
Roberto Hirochi Herai, Ryan A Szeto, Cleber A Trujillo, Alysson Renato Muotri
Response to Comment on "Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment". Science (New York, N.Y.) 374 (6565) (2021)
G Carola, D Malagarriga, C Calatayud, Meritxell Pons-Espinal, L Blasco-Agell, Y Richaud-Patin, I Fernandez-Carasa, V Baruffi, S Beltramone, E Molina, Patrizia Dell'Era, J J Toledo-Aral, E Tolosa, Alysson Renato Muotri, Jordi García-Ojalvo, Jordi Soriano, Ángel Raya, Antonella Consiglio
Parkinson's disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration. NPJ Parkinson's disease 7 (1) (2021)
Cleber A Trujillo, Edward S Rice, Nathan K Schaefer, Isaac A Chaim, Emily C Wheeler, Assael A Madrigal, Justin Buchanan, Sebastian Preissl, Allen Wang, Priscilla D Negraes, Ryan A Szeto, Roberto Hirochi Herai, Alik Huseynov, Mariana S A Ferraz, Fernando da Silva Borges, Alexandre Hiroaki Kihara, Ashley Byrne, Maximillian G Marin, Christopher Vollmers, Angela N Brooks, Jonathan D Lautz, Katerina Semendeferi, Joshua D Kapp, Gene W Yeo, Stephen E P Smith, Richard E Green, Alysson Renato Muotri
Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment. Science (New York, N.Y.) 371 (6530) (2021)
José Ricardo Teixeira Júnior, Ryan A Szeto, Vinicius M A Carvalho, Alysson Renato Muotri, Fabio Papes
Transcription factor 4 and its association with psychiatric disorders. Translational psychiatry 11 (1) (2021)
Jorge Urresti, Pan Zhang, Patricia Moran-Losada, Nam-Kyung Yu, Priscilla D Negraes, Cleber A Trujillo, Danny Antaki, Megha Amar, Kevin Chau, Akula Bala Pramod, Jolene Diedrich, Leon Tejwani, Sarah Romero, Jonathan Sebat, John Yates Iii, Alysson Renato Muotri, Lilia M Iakoucheva
Correction: Cortical organoids model early brain development disrupted by 16p11.2 copy number variants in autism. Molecular psychiatry (2021)
Roy Maimon, Carlos Chillon-Marinas, Cedric E Snethlage, Sarthak M Singhal, Melissa McAlonis-Downes, Karen Ling, Frank Rigo, C Frank Bennett, Sandrine Da Cruz, Thomas S Hnasko, Alysson Renato Muotri, Don W Cleveland
Therapeutically viable generation of neurons with antisense oligonucleotide suppression of PTB. Nature neuroscience 24 (8) (2021)
Cleber A Trujillo, Jason W Adams, Priscilla D Negraes, Cassiano Carromeu, Leon Tejwani, Allan Acab, Ben Tsuda, Charles A Thomas, Neha Sodhi, Katherine M Fichter, Sarah Romero, Fabian Zanella, Terrence J Sejnowski, Henning Ulrich, Alysson Renato Muotri
Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoids. EMBO molecular medicine 13 (1) (2020)
Alysson Renato Muotri
Brain organoids and insights on human evolution. F1000Research 8 (2019)
Spencer M Moore, Jason S Seidman, Jacob Ellegood, Richard Gao, Alex Savchenko, Ty D Troutman, Yohei Abe, Josh Stender, Daehoon Lee, Sicong Wang, Bradley Voytek, Jason P Lerch, Hoonkyo Suh, Christopher K Glass, Alysson Renato Muotri
Setd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice. Translational psychiatry 9 (1) (2019)
Jan Strnadel, Cassiano Carromeu, Cedric Bardy, Michael Navarro, Oleksandr Platoshyn, Andreas Nørgaard Glud, Silvia Marsala, Jozef Kafka, Atsushi Miyanohara, Tomohisa Kato, Takahiro Tadokoro, Michael P Hefferan, Kota Kamizato, Tetsuya Yoshizumi, Stefan Juhas, Jana Juhasova, Chak-Sum Ho, Taba Kheradmand, PeiXi Chen, Dasa Bohaciakova, Marian Hruska-Plochan, Andrew J Todd, Shawn P Driscoll, Thomas D Glenn, Samuel L Pfaff, Jiri Klima, Joseph Ciacci, Eric Curtis, Fred H Gage, Jack D Bui, Kazuhiko Yamada, Alysson Renato Muotri, Martin Marsala
Survival of syngeneic and allogeneic iPSC-derived neural precursors after spinal grafting in minipigs. Science translational medicine 10 (440) (2019)
Alysson Renato Muotri
Autism spectrum disorders: Challenges and perspectives. Developmental neurobiology 78 (5) (2018)
Isabella R Fernandes, Ana C P Cruz, Adriano Ferrasa, Dylan Phan, Roberto H Herai, Alysson Renato Muotri
Genetic variations on SETD5 underlying autistic conditions. Developmental neurobiology 78 (5) (2018)
Lucas L Baltussen, Priscilla D Negraes, Margaux Silvestre, Suzanne Claxton, Max Moeskops, Evangelos Christodoulou, Helen R Flynn, Ambrosius P Snijders, Alysson Renato Muotri, Sila K Ultanir
Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics. The EMBO journal 37 (24) (2018)
William M Brandler, Danny Antaki, Madhusudan Gujral, Morgan L Kleiber, Joe Whitney, Michelle S Maile, Oanh Hong, Timothy R Chapman, Shirley Tan, Prateek Tandon, Timothy Pang, Shih C Tang, Keith K Vaux, Yan Yang, Eoghan Harrington, Sissel Juul, Daniel J Turner, Bhooma Thiruvahindrapuram, Gaganjot Kaur, Zhuozhi Wang, Stephen F Kingsmore, Joseph G Gleeson, Denis Bisson, Boyko Kakaradov, Amalio Telenti, J Craig Venter, Roser Corominas, Claudio Toma, Bru Cormand, Isabel Rueda, Silvina Guijarro, Karen S Messer, Caroline M Nievergelt, María Jesús Arranz, Eric Courchesne, Karen Pierce, Alysson Renato Muotri, Lilia M Iakoucheva, Amaia Hervas, Stephen W Scherer, Christina Corsello, Jonathan Sebat
Paternally inherited cis-regulatory structural variants are associated with autism. Science (New York, N.Y.) 360 (6386) (2018)