Fred H Gage

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 84

Top Topics

Duchenne Muscular Dystrophy

Bipolar Disorder

Top Venues

Molecular psychiatry

Science (New York, N.Y.)

NPJ Parkinson's disease

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Sonia Podvin, Jeffrey R Jones, Austin Kang, Ryan Goodman, Patrick Reed, Christopher B Lietz, Joshua Then, Kelly C Lee, Lisa T Eyler, Dilip V Jeste, Fred H Gage, Vivian Hook
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures. Molecular psychiatry (2024)
Sara Zocher, Asako McCloskey, Anne Karasinsky, Roberta Schulte, Ulrike Anne Friedrich, Matthias Lesche, Nicole Rund, Fred H Gage, Martin W Hetzer, Tomohisa Toda
Lifelong persistence of nuclear RNAs in the mouse brain. Science (New York, N.Y.) 384 (6691) (2024)
Sara Zocher, Asako McCloskey, Anne Karasinsky, Roberta Schulte, Ulrike Anne Friedrich, Matthias Lesche, Nicole Rund, Fred H Gage, Martin W Hetzer, Tomohisa Toda
Lifelong persistence of nuclear RNAs in the mouse brain. Science (New York, N.Y.) 384 (6691) (2024)
Sonia Podvin, Jeffrey R Jones, Austin Kang, Ryan Goodman, Patrick Reed, Christopher B Lietz, Joshua Then, Kelly C Lee, Lisa T Eyler, Dilip V Jeste, Fred H Gage, Vivian Hook
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures. Molecular psychiatry 29 (5) (2024)
Tobias T Schmidt, Carly Tyer, Preeyesh Rughani, Candy Haggblom, Jeffrey R Jones, Xiaoguang Dai, Kelly A Frazer, Fred H Gage, Sissel Juul, Scott Hickey, Jan Karlseder
High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer. Nature communications 15 (1) (2024)
Idan Rosh, Utkarsh Tripathi, Yara Hussein, Wote Amelo Rike, Jose Djamus, Boris Shklyar, Andreea Manole, Henry Houlden, Jurgen Winkler, Fred H Gage, Shani Stern
Synaptic dysfunction and extracellular matrix dysregulation in dopaminergic neurons from sporadic and E326K-GBA1 Parkinson's disease patients. NPJ Parkinson's disease 10 (1) (2024)
Shani Stern, Lei Zhang, Meiyan Wang, Rebecca Wright, Idan Rosh, Yara Hussein, Tchelet Stern, Ashwani Choudhary, Utkarsh Tripathi, Patrick Reed, Hagit Sadis, Ritu Nayak, Aviram Shemen, Karishma Agarwal, Diogo Cordeiro, David Peles, Yuqing Hang, Ana P D Mendes, Tithi D Baul, Julien George Roth, Shashank Coorapati, Marco P M Boks, W Richard McCombie, Hilleke E Hulshoff Pol, Kristen J Brennand, János M Réthelyi, Rene S Kahn, Maria C Marchetto, Fred H Gage
Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission. Molecular psychiatry (2024)
Paras S Minhas, Jeffrey R Jones, Amira Latif-Hernandez, Yuki Sugiura, Aarooran S Durairaj, Qian Wang, Siddhita D Mhatre, Takeshi Uenaka, Joshua Crapser, Travis E Conley, Hannah E Ennerfelt, Yoo Jin Jung, Ling Liu, Praveena Prasad, Brenita C Jenkins, Yeonglong Albert Ay, Matthew Matrongolo, Ryan Goodman, Traci Newmeyer, Kelly J Heard, Austin Kang, Edward N Wilson, Tao Yang, Erik M Ullian, Geidy E Serrano, Thomas G Beach, Marius Wernig, Joshua D Rabinowitz, Makoto Suematsu, Frank M Longo, Melanie R McReynolds, Fred H Gage, Katrin I Andreasson
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies. Science (New York, N.Y.) 385 (6711) (2024)
Sonia Podvin, Jeffrey R Jones, Austin Kang, Ryan Goodman, Patrick Reed, Christopher B Lietz, Joshua Then, Kelly C Lee, Lisa T Eyler, Dilip V Jeste, Fred H Gage, Vivian Hook
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures. Molecular psychiatry (2024)
Paras S Minhas, Jeffrey R Jones, Amira Latif-Hernandez, Yuki Sugiura, Aarooran S Durairaj, Qian Wang, Siddhita D Mhatre, Takeshi Uenaka, Joshua Crapser, Travis E Conley, Hannah E Ennerfelt, Yoo Jin Jung, Ling Liu, Praveena Prasad, Brenita C Jenkins, Yeonglong Albert Ay, Matthew Matrongolo, Ryan Goodman, Traci Newmeyer, Kelly J Heard, Austin Kang, Edward N Wilson, Tao Yang, Erik M Ullian, Geidy E Serrano, Thomas G Beach, Marius Wernig, Joshua D Rabinowitz, Makoto Suematsu, Frank M Longo, Melanie R McReynolds, Fred H Gage, Katrin I Andreasson
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies. Science (New York, N.Y.) 385 (6711) (2024)
Utkarsh Tripathi, Idan Rosh, Ran Ben Ezer, Ritu Nayak, Yara Hussein, Ashwani Choudhary, Jose Djamus, Andreea Manole, Henry Houlden, Fred H Gage, Shani Stern
Upregulated ECM genes and increased synaptic activity in Parkinson's human DA neurons with PINK1/ PRKN mutations. NPJ Parkinson's disease 10 (1) (2024)
Sara Zocher, Asako McCloskey, Anne Karasinsky, Roberta Schulte, Ulrike Anne Friedrich, Matthias Lesche, Nicole Rund, Fred H Gage, Martin W Hetzer, Tomohisa Toda
Lifelong persistence of nuclear RNAs in the mouse brain. Science (New York, N.Y.) 384 (6691) (2024)
Sonia Podvin, Jeffrey R Jones, Austin Kang, Ryan Goodman, Patrick Reed, Christopher B Lietz, Joshua Then, Kelly C Lee, Lisa T Eyler, Dilip V Jeste, Fred H Gage, Vivian Hook
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures. Molecular psychiatry 29 (5) (2024)
Idan Rosh, Utkarsh Tripathi, Yara Hussein, Wote Amelo Rike, Jose Djamus, Boris Shklyar, Andreea Manole, Henry Houlden, Jurgen Winkler, Fred H Gage, Shani Stern
Synaptic dysfunction and extracellular matrix dysregulation in dopaminergic neurons from sporadic and E326K-GBA1 Parkinson's disease patients. NPJ Parkinson's disease 10 (1) (2024)
Utkarsh Tripathi, Idan Rosh, Ran Ben Ezer, Ritu Nayak, Yara Hussein, Ashwani Choudhary, Jose Djamus, Andreea Manole, Henry Houlden, Fred H Gage, Shani Stern
Upregulated ECM genes and increased synaptic activity in Parkinson's human DA neurons with PINK1/ PRKN mutations. NPJ Parkinson's disease 10 (1) (2024)
Idan Rosh, Utkarsh Tripathi, Yara Hussein, Wote Amelo Rike, Jose Djamus, Boris Shklyar, Andreea Manole, Henry Houlden, Jurgen Winkler, Fred H Gage, Shani Stern
Synaptic dysfunction and extracellular matrix dysregulation in dopaminergic neurons from sporadic and E326K-GBA1 Parkinson's disease patients. NPJ Parkinson's disease 10 (1) (2024)
Meiyan Wang, Lei Zhang, Sammy Weiser Novak, Jingting Yu, Iryna S Gallina, Lynne L Xu, Christina K Lim, Sarah Fernandes, Maxim N Shokhirev, April E Williams, Monisha D Saxena, Shashank Coorapati, Sarah L Parylak, Cristian Quintero, Elsa Molina, Leonardo R Andrade, Uri Manor, Fred H Gage
Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain. Nature biotechnology (2024)
Meiyan Wang, Lei Zhang, Sammy Weiser Novak, Jingting Yu, Iryna S Gallina, Lynne L Xu, Christina K Lim, Sarah Fernandes, Maxim N Shokhirev, April E Williams, Monisha D Saxena, Shashank Coorapati, Sarah L Parylak, Cristian Quintero, Elsa Molina, Leonardo R Andrade, Uri Manor, Fred H Gage
Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain. Nature biotechnology (2024)
Meiyan Wang, Lei Zhang, Sammy Weiser Novak, Jingting Yu, Iryna S Gallina, Lynne L Xu, Christina K Lim, Sarah Fernandes, Maxim N Shokhirev, April E Williams, Monisha D Saxena, Shashank Coorapati, Sarah L Parylak, Cristian Quintero, Elsa Molina, Leonardo R Andrade, Uri Manor, Fred H Gage
Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain. Nature biotechnology (2024)
Sonia Podvin, Jeffrey R Jones, Austin Kang, Ryan Goodman, Patrick Reed, Christopher B Lietz, Joshua Then, Kelly C Lee, Lisa T Eyler, Dilip V Jeste, Fred H Gage, Vivian Hook
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures. Molecular psychiatry (2024)
Meiyan Wang, Lei Zhang, Sammy Weiser Novak, Jingting Yu, Iryna S Gallina, Lynne L Xu, Christina K Lim, Sarah Fernandes, Maxim N Shokhirev, April E Williams, Monisha D Saxena, Shashank Coorapati, Sarah L Parylak, Cristian Quintero, Elsa Molina, Leonardo R Andrade, Uri Manor, Fred H Gage
Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain. Nature biotechnology (2024)
Tobias T Schmidt, Carly Tyer, Preeyesh Rughani, Candy Haggblom, Jeffrey R Jones, Xiaoguang Dai, Kelly A Frazer, Fred H Gage, Sissel Juul, Scott Hickey, Jan Karlseder
High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer. Nature communications 15 (1) (2024)
Sara Zocher, Asako McCloskey, Anne Karasinsky, Roberta Schulte, Ulrike Anne Friedrich, Matthias Lesche, Nicole Rund, Fred H Gage, Martin W Hetzer, Tomohisa Toda
Lifelong persistence of nuclear RNAs in the mouse brain. Science (New York, N.Y.) 384 (6691) (2024)
Sara Zocher, Asako McCloskey, Anne Karasinsky, Roberta Schulte, Ulrike Anne Friedrich, Matthias Lesche, Nicole Rund, Fred H Gage, Martin W Hetzer, Tomohisa Toda
Lifelong persistence of nuclear RNAs in the mouse brain. Science (New York, N.Y.) 384 (6691) (2024)
Paras S Minhas, Jeffrey R Jones, Amira Latif-Hernandez, Yuki Sugiura, Aarooran S Durairaj, Qian Wang, Siddhita D Mhatre, Takeshi Uenaka, Joshua Crapser, Travis E Conley, Hannah E Ennerfelt, Yoo Jin Jung, Ling Liu, Praveena Prasad, Brenita C Jenkins, Yeonglong Albert Ay, Matthew Matrongolo, Ryan Goodman, Traci Newmeyer, Kelly J Heard, Austin Kang, Edward N Wilson, Tao Yang, Erik M Ullian, Geidy E Serrano, Thomas G Beach, Marius Wernig, Joshua D Rabinowitz, Makoto Suematsu, Frank M Longo, Melanie R McReynolds, Fred H Gage, Katrin I Andreasson
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies. Science (New York, N.Y.) 385 (6711) (2024)
Sonia Podvin, Jeffrey R Jones, Austin Kang, Ryan Goodman, Patrick Reed, Christopher B Lietz, Joshua Then, Kelly C Lee, Lisa T Eyler, Dilip V Jeste, Fred H Gage, Vivian Hook
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures. Molecular psychiatry 29 (5) (2024)
Meiyan Wang, Lei Zhang, Sammy Weiser Novak, Jingting Yu, Iryna S Gallina, Lynne L Xu, Christina K Lim, Sarah Fernandes, Maxim N Shokhirev, April E Williams, Monisha D Saxena, Shashank Coorapati, Sarah L Parylak, Cristian Quintero, Elsa Molina, Leonardo R Andrade, Uri Manor, Fred H Gage
Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain. Nature biotechnology (2024)
Tobias T Schmidt, Carly Tyer, Preeyesh Rughani, Candy Haggblom, Jeffrey R Jones, Xiaoguang Dai, Kelly A Frazer, Fred H Gage, Sissel Juul, Scott Hickey, Jan Karlseder
High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer. Nature communications 15 (1) (2024)
Utkarsh Tripathi, Idan Rosh, Ran Ben Ezer, Ritu Nayak, Yara Hussein, Ashwani Choudhary, Jose Djamus, Andreea Manole, Henry Houlden, Fred H Gage, Shani Stern
Upregulated ECM genes and increased synaptic activity in Parkinson's human DA neurons with PINK1/ PRKN mutations. NPJ Parkinson's disease 10 (1) (2024)
McKinzie A Garrison, Yeongjun Jang, Taejeong Bae, Adriana Cherskov, Sarah B Emery, Liana Fasching, Attila Jones, John B Moldovan, Cindy Molitor, Sirisha Pochareddy, Mette A Peters, Joo-Heon Shin, Yifan Wang, Xiaoxu Yang, Schahram Akbarian, Andrew Chess, Fred H Gage, Joseph G Gleeson, Jeffrey M Kidd, Michael J McConnell, Ryan E Mills, John V Moran, Peter J Park, Nenad Sestan, Alexander Eckehart Urban, Flora M Vaccarino, Christopher A Walsh, Daniel R Weinberger, Sarah J Wheelan, Alexej Abyzov, null null
Genomic data resources of the Brain Somatic Mosaicism Network for neuropsychiatric diseases. Scientific data 10 (1) (2023)
Liron Mizrahi, Ashwani Choudhary, Polina Ofer, Gabriela Goldberg, Elena Milanesi, John R Kelsoe, David Gurwitz, Martin Alda, Fred H Gage, Shani Stern
Immunoglobulin genes expressed in lymphoblastoid cell lines discern and predict lithium response in bipolar disorder patients. Molecular psychiatry (2023)
Larissa Traxler, Raffaella Lucciola, Joseph R Herdy, Jeffrey R Jones, Jerome Mertens, Fred H Gage
Neural cell state shifts and fate loss in ageing and age-related diseases. Nature reviews. Neurology (2023)
Gerd Kempermann, Hongjun Song, Fred H Gage
Adult neurogenesis in the hippocampus. Hippocampus (2023)
Sarah L Parylak, Fan Qiu, Sara B Linker, Iryna S Gallina, Christina K Lim, David Preciado, Aidan H McDonald, Xavier Zhou, Fred H Gage
Neuronal activity-related transcription is blunted in immature compared to mature dentate granule cells. Hippocampus 33 (4) (2023)
Gerd Kempermann, Hongjun Song, Fred H Gage
Adult neurogenesis in the hippocampus. Hippocampus 33 (4) (2023)
Sarah L Parylak, Fan Qiu, Sara B Linker, Iryna S Gallina, Christina K Lim, David Preciado, Aidan H McDonald, Xavier Zhou, Fred H Gage
Neuronal activity-related transcription is blunted in immature compared to mature dentate granule cells. Hippocampus 33 (4) (2023)
Sarah L Parylak, Fan Qiu, Sara B Linker, Iryna S Gallina, Christina K Lim, David Preciado, Aidan H McDonald, Xavier Zhou, Fred H Gage
Neuronal activity-related transcription is blunted in immature compared to mature dentate granule cells. Hippocampus (2023)
Vipavee Niemsiri, Sara Brin Rosenthal, Caroline M Nievergelt, Adam X Maihofer, Maria C Marchetto, Renata Santos, Tatyana Shekhtman, Ney Alliey-Rodriguez, Amit Anand, Yokesh Balaraman, Wade H Berrettini, Holli Bertram, Katherine E Burdick, Joseph R Calabrese, Cynthia V Calkin, Carla Conroy, William H Coryell, Anna DeModena, Lisa T Eyler, Scott Feeder, Carrie Fisher, Nicole Frazier, Mark A Frye, Keming Gao, Julie S Garnham, Elliot S Gershon, Fernando S Goes, Toyomi Goto, Gloria J Harrington, Petter Jakobsen, Masoud Kamali, Marisa Kelly, Susan G Leckband, Falk W Lohoff, Michael J McCarthy, Melvin G McInnis, David Craig, Caitlin E Millett, Francis Mondimore, Gunnar Morken, John I Nurnberger, Claire O' Donovan, Ketil J Øedegaard, Kelly Ryan, Martha Schinagle, Paul D Shilling, Claire Slaney, Emma K Stapp, Andrea Stautland, Bruce Tarwater, Peter P Zandi, Martin Alda, Kathleen M Fisch, Fred H Gage, John R Kelsoe
Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis. Molecular psychiatry (2023)
Gerd Kempermann, Hongjun Song, Fred H Gage
Adult neurogenesis in the hippocampus. Hippocampus 33 (4) (2023)
Sergiu P Pașca, Paola Arlotta, Helen S Bateup, J Gray Camp, Silvia Cappello, Fred H Gage, Jürgen Arthur Knoblich, Arnold R Kriegstein, Madeline A Lancaster, Guo-Li Ming, Alysson R Muotri, In-Hyun Park, Orly Reiner, Hongjun Song, Lorenz Studer, Sally Temple, Giuseppe Testa, Barbara Treutlein, Flora M Vaccarino
A nomenclature consensus for nervous system organoids and assembloids. Nature 609 (7929) (2022)
Madison N Wilson, Martin Thunemann, Xin Liu, Yichen Lu, Francesca Puppo, Jason W Adams, Jeong-Hoon Kim, Mehrdad Ramezani, Donald P Pizzo, Srdjan Djurovic, Ole Andreas Andreassen, Abed AlFatah Mansour, Fred H Gage, Alysson R Muotri, Anna Devor, Duygu Kuzum
Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex. Nature communications 13 (1) (2022)
Shani Stern, Shong Lau, Andreea Manole, Idan Rosh, Menachem Mendel Percia, Ran Ben Ezer, Maxim N Shokhirev, Fan Qiu, Simon Schafer, Abed AlFatah Mansour, Kile P Mangan, Tchelet Stern, Polina Ofer, Yam Stern, Ana Paula Diniz Mendes, Jose Djamus, Lynne Randolph Moore, Ritu Nayak, Sapir Havusha Laufer, Aidan Aicher, Amanda Rhee, Thomas L Wong, Thao Nguyen, Sara B Linker, Beate Winner, Beatriz C Freitas, Eugenia Jones, Irit Sagi, Cedric Bardy, Alexis Brice, Juergen Winkler, Maria C Marchetto, Fred H Gage
Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson's disease patients. NPJ Parkinson's disease 8 (1) (2022)
Mark van den Hurk, Shong Lau, Maria C Marchetto, Jerome Mertens, Shani Stern, Olga Corti, Alexis Brice, Beate Winner, Jürgen Winkler, Fred H Gage, Cedric Bardy
Druggable transcriptomic pathways revealed in Parkinson's patient-derived midbrain neurons. NPJ Parkinson's disease 8 (1) (2022)
Madison N Wilson, Martin Thunemann, Xin Liu, Yichen Lu, Francesca Puppo, Jason W Adams, Jeong-Hoon Kim, Mehrdad Ramezani, Donald P Pizzo, Srdjan Djurovic, Ole Andreas Andreassen, Abed AlFatah Mansour, Fred H Gage, Alysson R Muotri, Anna Devor, Duygu Kuzum
Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex. Nature communications 13 (1) (2022)
Madison N Wilson, Martin Thunemann, Xin Liu, Yichen Lu, Francesca Puppo, Jason W Adams, Jeong-Hoon Kim, Mehrdad Ramezani, Donald P Pizzo, Srdjan Djurovic, Ole Andreas Andreassen, Abed AlFatah Mansour, Fred H Gage, Alysson R Muotri, Anna Devor, Duygu Kuzum
Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex. Nature communications 13 (1) (2022)
Yanhong Shi, Ronald M Evans, Fred H Gage
Oleic acid regulates hippocampal neurogenesis as a TLX ligand. Proceedings of the National Academy of Sciences of the United States of America 119 (15) (2022)
Madison N Wilson, Martin Thunemann, Xin Liu, Yichen Lu, Francesca Puppo, Jason W Adams, Jeong-Hoon Kim, Mehrdad Ramezani, Donald P Pizzo, Srdjan Djurovic, Ole Andreas Andreassen, Abed AlFatah Mansour, Fred H Gage, Alysson R Muotri, Anna Devor, Duygu Kuzum
Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex. Nature communications 13 (1) (2022)
Dylan A Reid, Patrick J Reed, Johannes C M Schlachetzki, Ioana I Nitulescu, Grace Chou, Enoch C Tsui, Jeffrey R Jones, Sahaana Chandran, Ake T Lu, Claire A McClain, Jean H Ooi, Tzu-Wen Wang, Addison J Lana, Sara B Linker, Anthony S Ricciardulli, Shong Lau, Simon T Schafer, Steve Horvath, Jesse R Dixon, Nasun Hah, Christopher K Glass, Fred H Gage
Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons. Science (New York, N.Y.) 372 (6537) (2021)
Kelly J Heard, Maxim N Shokhirev, Caroline Becronis, Callie Fredlender, Nadia Zahid, Amy T Le, Yuan Ji, Michelle K Skime, Timothy Nelson, Daniel Hall-Flavin, Richard M Weinshilboum, Fred H Gage, Krishna C Vadodaria
Chronic cortisol differentially impacts stem cell-derived astrocytes from major depressive disorder patients. Translational psychiatry 11 (1) (2021)
Nako Nakatsuka, Kelly J Heard, Alix Faillétaz, Dmitry Momotenko, János Vörös, Fred H Gage, Krishna C Vadodaria
Sensing serotonin secreted from human serotonergic neurons using aptamer-modified nanopipettes. Molecular psychiatry 26 (7) (2021)
Shinichi Fukuda, Akhil Varshney, Benjamin J Fowler, Shao-Bin Wang, Siddharth Narendran, Kameshwari Ambati, Tetsuhiro Yasuma, Joseph Magagnoli, Hannah Leung, Shuichiro Hirahara, Yosuke Nagasaka, Reo Yasuma, Ivana Apicella, Felipe Pereira, Ryan D Makin, Eamonn Magner, Xinan Liu, Jian Sun, Mo Wang, Kirstie Baker, Kenneth M Marion, Xiwen Huang, Elmira Baghdasaryan, Meenakshi Ambati, Vidya L Ambati, Akshat Pandey, Lekha Pandya, Tammy Cummings, Daipayan Banerjee, Peirong Huang, Praveen Yerramothu, Genrich V Tolstonog, Ulrike Held, Jennifer A Erwin, Apua C M Paquola, Joseph R Herdy, Yuichiro Ogura, Hiroko Terasaki, Tetsuro Oshika, Shaban Darwish, Ramendra K Singh, Saghar Mozaffari, Deepak Bhattarai, Kyung Bo Kim, James W Hardin, Charles L Bennett, David R Hinton, Timothy E Hanson, Christian Röver, Keykavous Parang, Nagaraj Kerur, Jinze Liu, Brian C Werner, S Scott Sutton, Srinivas R Sadda, Gerald G Schumann, Bradley D Gelfand, Fred H Gage, Jayakrishna Ambati
Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America 118 (6) (2021)
Himanshu K Mishra, Noelle M Ying, Angelica Luis, Heather Wei, Metta Nguyen, Timothy Nakhla, Sara Vandenburgh, Martin Alda, Wade H Berrettini, Kristen J Brennand, Joseph R Calabrese, William H Coryell, Mark A Frye, Fred H Gage, Elliot S Gershon, Melvin G McInnis, Caroline M Nievergelt, Michael C Neale, Paul D Shilling, Ketil J Oedegaard, Peter P Zandi, null null, John R Kelsoe, David K Welsh, Michael J McCarthy
Circadian rhythms in bipolar disorder patient-derived neurons predict lithium response: preliminary studies. Molecular psychiatry 26 (7) (2021)
Renata Santos, Sara B Linker, Shani Stern, Ana P D Mendes, Maxim N Shokhirev, Galina Erikson, Lynne Randolph-Moore, Vipula Racha, Yeni Kim, John R Kelsoe, Anne G Bang, Martin Alda, Maria C Marchetto, Fred H Gage
Deficient LEF1 expression is associated with lithium resistance and hyperexcitability in neurons derived from bipolar disorder patients. Molecular psychiatry 26 (6) (2021)
Kun Tan, Matthew E Kim, Hye-Won Song, David Skarbrevik, Eric Babajanian, Tracy A Bedrosian, Fred H Gage, Miles F Wilkinson
The Rhox gene cluster suppresses germline LINE1 transposition. Proceedings of the National Academy of Sciences of the United States of America 118 (23) (2021)
Vera Gorbunova, Andrei Seluanov, Paolo Mita, Wilson McKerrow, David Fenyo, Jef D Boeke, Sara B Linker, Fred H Gage, Jill A Kreiling, Anna P Petrashen, Trenton A Woodham, Jackson R Taylor, Stephen L Helfand, John M Sedivy
The role of retrotransposable elements in ageing and age-associated diseases. Nature 596 (7870) (2021)
Gisele Pereira Dias, Tytus Murphy, Doris Stangl, Selda Ahmet, Benjamin Morisse, Alina Nix, Lindsey J Aimone, James B Aimone, Makoto Kuro-O, Fred H Gage, Sandrine Thuret
Intermittent fasting enhances long-term memory consolidation, adult hippocampal neurogenesis, and expression of longevity gene Klotho. Molecular psychiatry (2021)
Stephen Johnston, Sarah L Parylak, Stacy Kim, Nolan Mac, Christina Lim, Iryna Gallina, Cooper Bloyd, Alexander Newberry, Christian D Saavedra, Ondrej Novak, J Tiago Gonçalves, Fred H Gage, Matthew Shtrahman
AAV ablates neurogenesis in the adult murine hippocampus. eLife 10 (2021)
Simon T Schafer, Fred H Gage
To eat, or not to eat, that is the question: Neural stem cells escape phagocytosis in autism with macrocephaly. Proceedings of the National Academy of Sciences of the United States of America 118 (19) (2021)
Tracy A Bedrosian, Judith Houtman, Juan Sebastián Eguiguren, Saeed Ghassemzadeh, Nicole Rund, Nicole M Novaresi, Lauren Hu, Sarah L Parylak, Ahmet M Denli, Lynne Randolph-Moore, Takashi Namba, Fred H Gage, Tomohisa Toda
Lamin B1 decline underlies age-related loss of adult hippocampal neurogenesis. The EMBO journal 40 (3) (2020)
Wei Shen, Qiu-Wen Wang, Yao-Nan Liu, Maria C Marchetto, Sara Linker, Si-Yao Lu, Yun Chen, Chuihong Liu, Chongye Guo, Zhikai Xing, Wei Shi, John R Kelsoe, Martin Alda, Hongwei Wang, Yi Zhong, Sen-Fang Sui, Mei Zhao, Yiming Yang, Shuangli Mi, Liping Cao, Fred H Gage, Jun Yao
Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice. Proceedings of the National Academy of Sciences of the United States of America 117 (8) (2020)
Qiu-Wen Wang, Si-Yao Lu, Yao-Nan Liu, Yun Chen, Hui Wei, Wei Shen, Yan-Fen Chen, Chong-Lei Fu, Ying-Han Wang, Anbang Dai, Xuan Huang, Fred H Gage, Qi Xu, Jun Yao
Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity. Proceedings of the National Academy of Sciences of the United States of America 117 (49) (2020)
Thalita Figueiredo, Ana P D Mendes, Danielle P Moreira, Ernesto Goulart, Danyllo F Oliveira, Gerson S Kobayashi, Shani Stern, Fernando Kok, Maria C Marchetto, Renata Santos, Fred H Gage, Mayana Zatz
Inositol monophosphatase 1 (IMPA1) mutation in intellectual disability patients impairs neurogenesis but not gliogenesis. Molecular psychiatry 26 (7) (2020)
Wendy Wenderski, Lu Wang, Andrey Krokhotin, Jessica J Walsh, Hongjie Li, Hirotaka Shoji, Shereen Ghosh, Renee D George, Erik L Miller, Laura Elias, Mark A Gillespie, Esther Y Son, Brett T Staahl, Seung Tae Baek, Valentina Stanley, Cynthia Moncada, Zohar Shipony, Sara B Linker, Maria C N Marchetto, Fred H Gage, Dillon Chen, Tipu Sultan, Maha S Zaki, Jeffrey A Ranish, Tsuyoshi Miyakawa, Liqun Luo, Robert C Malenka, Gerald R Crabtree, Joseph G Gleeson
Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism. Proceedings of the National Academy of Sciences of the United States of America 117 (18) (2020)
Alexi Nott, Inge R Holtman, Nicole G Coufal, Johannes C M Schlachetzki, Miao Yu, Rong Hu, Claudia Z Han, Monique Pena, Jiayang Xiao, Yin Wu, Zahara Keulen, Martina P Pasillas, Carolyn O'Connor, Christian K Nickl, Simon T Schafer, Zeyang Shen, Robert A Rissman, James B Brewer, David Gosselin, David D Gonda, Michael L Levy, Michael G Rosenfeld, Graham McVicker, Fred H Gage, Bing Ren, Christopher K Glass
Brain cell type-specific enhancer-promoter interactome maps and disease-risk association. Science (New York, N.Y.) 366 (6469) (2019)
Maria Carolina Marchetto, Branka Hrvoj-Mihic, Bilal Ersen Kerman, Diana X Yu, Krishna C Vadodaria, Sara B Linker, Iñigo Narvaiza, Renata Santos, Ahmet M Denli, Ana Pd Mendes, Ruth Oefner, Jonathan Cook, Lauren McHenry, Jaeson M Grasmick, Kelly Heard, Callie Fredlender, Lynne Randolph-Moore, Rijul Kshirsagar, Rea Xenitopoulos, Grace Chou, Nasun Hah, Alysson R Muotri, Krishnan Padmanabhan, Katerina Semendeferi, Fred H Gage
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells. eLife 8 (2019)
Jan Strnadel, Cassiano Carromeu, Cedric Bardy, Michael Navarro, Oleksandr Platoshyn, Andreas Nørgaard Glud, Silvia Marsala, Jozef Kafka, Atsushi Miyanohara, Tomohisa Kato, Takahiro Tadokoro, Michael P Hefferan, Kota Kamizato, Tetsuya Yoshizumi, Stefan Juhas, Jana Juhasova, Chak-Sum Ho, Taba Kheradmand, PeiXi Chen, Dasa Bohaciakova, Marian Hruska-Plochan, Andrew J Todd, Shawn P Driscoll, Thomas D Glenn, Samuel L Pfaff, Jiri Klima, Joseph Ciacci, Eric Curtis, Fred H Gage, Jack D Bui, Kazuhiko Yamada, Alysson Renato Muotri, Martin Marsala
Survival of syngeneic and allogeneic iPSC-derived neural precursors after spinal grafting in minipigs. Science translational medicine 10 (440) (2019)
Paul J Lucassen, Nicolas Toni, Gerd Kempermann, Jonas Frisen, Fred H Gage, Dick F Swaab
Limits to human neurogenesis-really? Molecular psychiatry 25 (10) (2019)
Joseph R Herdy, Simon Schafer, Yongsung Kim, Zoya Ansari, Dina Zangwill, Manching Ku, Apua Paquola, Hyungjun Lee, Jerome Mertens, Fred H Gage
Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons. eLife 8 (2019)
Krishna C Vadodaria, Yuan Ji, Michelle Skime, Apua C Paquola, Timothy Nelson, Daniel Hall-Flavin, Kelly J Heard, Callie Fredlender, Yalin Deng, James Elkins, Komal Dani, Amy T Le, Maria C Marchetto, Richard Weinshilboum, Fred H Gage
Altered serotonergic circuitry in SSRI-resistant major depressive disorder patient-derived neurons. Molecular psychiatry 24 (6) (2019)
Meiyan Wang, Lei Zhang, Fred H Gage
Microglia, complement and schizophrenia. Nature neuroscience 22 (3) (2019)
Meiyan Wang, Lei Zhang, Fred H Gage
Modeling neuropsychiatric disorders using human induced pluripotent stem cells. Protein & cell 11 (1) (2019)
Simon T Schafer, Apua C M Paquola, Shani Stern, David Gosselin, Manching Ku, Monique Pena, Thomas J M Kuret, Marvin Liyanage, Abed AlFatah Mansour, Baptiste N Jaeger, Maria C Marchetto, Christopher K Glass, Jerome Mertens, Fred H Gage
Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons. Nature neuroscience 22 (2) (2019)
Krishna C Vadodaria, Yuan Ji, Michelle Skime, Apua Paquola, Timothy Nelson, Daniel Hall-Flavin, Callie Fredlender, Kelly J Heard, Yalin Deng, Amy T Le, Sonia Dave, Lianna Fung, Xinyi Li, Maria C Marchetto, Richard Weinshilboum, Fred H Gage
Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons. Molecular psychiatry 24 (6) (2019)
Michael J McCarthy, Heather Wei, Caroline M Nievergelt, Andrea Stautland, Adam X Maihofer, David K Welsh, Paul Shilling, Martin Alda, Ney Alliey-Rodriguez, Amit Anand, Ole A Andreasson, Yokesh Balaraman, Wade H Berrettini, Holli Bertram, Kristen J Brennand, Joseph R Calabrese, Cynthia V Calkin, Ana Claasen, Clara Conroy, William H Coryell, David W Craig, Nicole D'Arcangelo, Anna Demodena, Srdjan Djurovic, Scott Feeder, Carrie Fisher, Nicole Frazier, Mark A Frye, Fred H Gage, Keming Gao, Julie Garnham, Elliot S Gershon, Kara Glazer, Fernando Goes, Toyomi Goto, Gloria Harrington, Petter Jakobsen, Masoud Kamali, Elizabeth Karberg, Marisa Kelly, Susan G Leckband, Falk Lohoff, Melvin G McInnis, Francis Mondimore, Gunnar Morken, John I Nurnberger, Sarah Obral, Ketil J Oedegaard, Abigail Ortiz, Megan Ritchey, Kelly Ryan, Martha Schinagle, Helle Schoeyen, Candice Schwebel, Martha Shaw, Tatyana Shekhtman, Claire Slaney, Emma K Stapp, Szabolcs Szelinger, Bruce Tarwater, Peter P Zandi, John R Kelsoe
Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 44 (3) (2018)
Se Hoon Choi, Enjana Bylykbashi, Zena K Chatila, Star W Lee, Benjamin Pulli, Gregory D Clemenson, Eunhee Kim, Alexander Rompala, Mary K Oram, Caroline Asselin, Jenna Aronson, Can Martin Zhang, Sean J Miller, Andrea Lesinski, John W Chen, Doo Yeon Kim, Henriette van Praag, Bruce M Spiegelman, Fred H Gage, Rudolph E Tanzi
Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model. Science (New York, N.Y.) 361 (6406) (2018)
Tracy A Bedrosian, Carolina Quayle, Nicole M Novaresi, Fred H Gage
Early life experience drives structural variation of neural genomes in mice. Science (New York, N.Y.) 359 (6382) (2018)
Zev N Kronenberg, Ian T Fiddes, David Gordon, Shwetha Murali, Stuart Cantsilieris, Olivia S Meyerson, Jason G Underwood, Bradley J Nelson, Mark J P Chaisson, Max L Dougherty, Katherine M Munson, Alex R Hastie, Mark E Diekhans, Fereydoun Hormozdiari, Nicola Lorusso, Kendra Hoekzema, Ruolan Qiu, Karen Clark, Archana Raja, AnneMarie E Welch, Melanie Sorensen, Carl Baker, Robert S Fulton, Joel Armstrong, Tina A Graves-Lindsay, Ahmet M Denli, Emma R Hoppe, PingHsun Hsieh, Christopher M Hill, Andy Wing Chun Pang, Joyce Lee, Ernest T Lam, Susan K Dutcher, Fred H Gage, Wesley C Warren, Jay Shendure, David Haussler, Valerie A Schneider, Han Cao, Mario Ventura, Richard K Wilson, Benedict Paten, Alex Aaron Pollen, Evan E Eichler
High-resolution comparative analysis of great ape genomes. Science (New York, N.Y.) 360 (6393) (2018)
Baptiste N Jaeger, Sara B Linker, Sarah L Parylak, Jerika J Barron, Iryna S Gallina, Christian D Saavedra, Conor Fitzpatrick, Christina K Lim, Simon T Schafer, Benjamin Lacar, Sebastian Jessberger, Fred H Gage
A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons. Nature communications 9 (1) (2018)
Michael J McConnell, John V Moran, Alexej Abyzov, Schahram Akbarian, Taejeong Bae, Isidro Cortes-Ciriano, Jennifer A Erwin, Liana Fasching, Diane A Flasch, Donald Freed, Javier Ganz, Andrew E Jaffe, Kenneth Y Kwan, Minseok Kwon, Michael A Lodato, Ryan E Mills, Apua C M Paquola, Rachel E Rodin, Chaggai Rosenbluh, Nenad Sestan, Maxwell A Sherman, Joo-Heon Shin, Saera Song, Richard E Straub, Jeremy Thorpe, Daniel R Weinberger, Alexander Eckehart Urban, Bo Zhou, Fred H Gage, Thomas Lehner, Geetha Senthil, Christopher A Walsh, Andrew Chess, Eric Courchesne, Joseph G Gleeson, Jeffrey M Kidd, Peter J Park, Jonathan Pevsner, Flora M Vaccarino, null null
Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network. Science (New York, N.Y.) 356 (6336) (2017)
Krishnan Padmanabhan, Fumitaka Osakada, Anna Tarabrina, Erin Kizer, Edward M Callaway, Fred H Gage, Terrence J Sejnowski
Diverse Representations of Olfactory Information in Centrifugal Feedback Projections. The Journal of neuroscience : the official journal of the Society for Neuroscience 36 (28) (2017)
David Gosselin, Dylan Skola, Nicole G Coufal, Inge R Holtman, Johannes C M Schlachetzki, Eniko Sajti, Baptiste N Jaeger, Carolyn O'Connor, Conor Fitzpatrick, Martina P Pasillas, Monique Pena, Amy Adair, David D Gonda, Michael L Levy, Richard M Ransohoff, Fred H Gage, Christopher K Glass
An environment-dependent transcriptional network specifies human microglia identity. Science (New York, N.Y.) 356 (6344) (2017)
David H Adamowicz, Subhojit Roy, David P Salmon, Douglas R Galasko, Lawrence A Hansen, Eliezer Masliah, Fred H Gage
Hippocampal α-Synuclein in Dementia with Lewy Bodies Contributes to Memory Impairment and Is Consistent with Spread of Pathology. The Journal of neuroscience : the official journal of the Society for Neuroscience 37 (7) (2016)
Benjamin J Harrison, Gayathri Venkat, James L Lamb, Tom H Hutson, Cassa Drury, Kristofer K Rau, Mary Barlett Bunge, Lorne M Mendell, Fred H Gage, Richard D Johnson, Caitlin E Hill, Eric C Rouchka, Lawrence David Falcon Moon, Jeffrey C Petruska
The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience 36 (15) (2016)
Hyung Joon Kim, Ahmet M Denli, Rebecca Wright, Tithi D Baul, Gregory D Clemenson, Ari S Morcos, Chunmei Zhao, Simon T Schafer, Fred H Gage, Mohamedi N Kagalwala
REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II. The Journal of neuroscience : the official journal of the Society for Neuroscience 35 (44) (2016)