James R Heath (James Heath)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 29

Top Venues

Communications chemistry

Nature

Nature communications

bioRxiv : the preprint server for biology

California Institute of Technology

This page only lists publications with an associated author ORCID identifier.

Affiliation History

California Institute of Technology Jan 02 2003

United States

Professor :: Chemistry

Publications

Jungwoo Kim, Rachel H Ng, JingXin Liang, Dazy Johnson, Young Shik Shin, Arion F Chatziioannou, Michael E Phelps, Wei Wei, Raphael D Levine, James R Heath
Kinetic Trajectories of Glucose Uptake in Single Cancer Cells Reveal a Drug-Induced Cell-State Change Within Hours of Drug Treatment. The journal of physical chemistry. B 128 (33) (2024)
Cameron T Flower, Chunmei Liu, Hui-Yu Chuang, Xiaoyang Ye, Hanjun Cheng, James R Heath, Wei Wei, Forest M White
Signaling and transcriptional dynamics underlying early adaptation to oncogenic BRAF inhibition. bioRxiv : the preprint server for biology (2024)
Jungwoo Kim, Rachel H Ng, JingXin Liang, Dazy Johnson, Young Shik Shin, Arion F Chatziioannou, Michael E Phelps, Wei Wei, Raphael D Levine, James R Heath
Kinetic Trajectories of Glucose Uptake in Single Cancer Cells Reveal a Drug-Induced Cell-State Change Within Hours of Drug Treatment. The journal of physical chemistry. B (2024)
Arundhati Nag, Amirhossein Mafi, Samir Das, Mary Beth Yu, Belen Alvarez-Villalonga, Soo-Kyung Kim, Yapeng Su, William A Goddard, James R Heath
Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions. Communications chemistry 6 (1) (2023)
William Chour, Jongchan Choi, Jingyi Xie, Mary E Chaffee, Thomas M Schmitt, Kathryn Finton, Diana C DeLucia, Alexander M Xu, Yapeng Su, Daniel G Chen, Rongyu Zhang, Dan Yuan, Sunga Hong, Alphonsus H C Ng, Jonah Z Butler, Rick A Edmark, Lesley C Jones, Kim M Murray, Songming Peng, Guideng Li, Roland K Strong, John K Lee, Jason D Goldman, Philip D Greenberg, James R Heath
Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis. Communications biology 6 (1) (2023)
Arundhati Nag, Amirhossein Mafi, Samir Das, Mary Beth Yu, Belen Alvarez-Villalonga, Soo-Kyung Kim, Yapeng Su, William A Goddard, James R Heath
Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions. Communications chemistry 6 (1) (2023)
Arundhati Nag, Amirhossein Mafi, Samir Das, Mary Beth Yu, Belen Alvarez-Villalonga, Soo-Kyung Kim, Yapeng Su, William A Goddard, James R Heath
Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions. Communications chemistry 6 (1) (2023)
James R Heath, Daniel G Chen, Jingyi Xie, Jongchan Choi, Rachel H Ng, Rongyu Zhang, Sarah Li, Rick Edmark, Hong Zheng, Benjamin D Solomon, Katie M Campbell, Egmidio Medina, Antoni Ribas, Purvesh Khatri, Lewis L Lanier, Philip Mease, Jason D Goldman, Yapeng Su
An NKG2A biased immune response confers protection for infection, autoimmune disease, and cancer. Research square (2023)
William Chour, Jongchan Choi, Jingyi Xie, Mary E Chaffee, Thomas M Schmitt, Kathryn Finton, Diana C DeLucia, Alexander M Xu, Yapeng Su, Daniel G Chen, Rongyu Zhang, Dan Yuan, Sunga Hong, Alphonsus H C Ng, Jonah Z Butler, Rick A Edmark, Lesley C Jones, Kim M Murray, Songming Peng, Guideng Li, Roland K Strong, John K Lee, Jason D Goldman, Philip D Greenberg, James R Heath
Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis. Communications biology 6 (1) (2023)
Cristina Puig-Saus, Barbara Sennino, Songming Peng, Clifford L Wang, Zheng Pan, Benjamin Yuen, Bhamini Purandare, Duo An, Boi B Quach, Diana Nguyen, Huiming Xia, Sameeha Jilani, Kevin Shao, Claire McHugh, John Greer, Phillip Peabody, Saparya Nayak, Jonathan Hoover, Sara Said, Kyle Jacoby, Olivier Dalmas, Susan P Foy, Andrew Conroy, Michael C Yi, Christine Shieh, William Lu, Katharine Heeringa, Yan Ma, Shahab Chizari, Melissa J Pilling, Marc Ting, Ramya Tunuguntla, Salemiz Sandoval, Robert Moot, Theresa Hunter, Sidi Zhao, Justin D Saco, Ivan Perez-Garcilazo, Egmidio Medina, Agustin Vega-Crespo, Ignacio Baselga-Carretero, Gabriel Abril-Rodriguez, Grace Cherry, Deborah J Wong, Jasreet Hundal, Bartosz Chmielowski, Daniel E Speiser, Michael T Bethune, Xiaoyan R Bao, Alena Gros, Malachi Griffith, Malachi Griffith, James R Heath, Alex Franzusoff, Stefanie J Mandl, Antoni Ribas
Neoantigen-targeted CD8 + T cell responses with PD-1 blockade therapy. Nature 615 (7953) (2023)
Arundhati Nag, Amirhossein Mafi, Samir Das, Mary Beth Yu, Belen Alvarez-Villalonga, Soo-Kyung Kim, Yapeng Su, William A Goddard, James R Heath
Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions. Communications chemistry 6 (1) (2023)
Cristina Puig-Saus, Barbara Sennino, Songming Peng, Clifford L Wang, Zheng Pan, Benjamin Yuen, Bhamini Purandare, Duo An, Boi B Quach, Diana Nguyen, Huiming Xia, Sameeha Jilani, Kevin Shao, Claire McHugh, John Greer, Phillip Peabody, Saparya Nayak, Jonathan Hoover, Sara Said, Kyle Jacoby, Olivier Dalmas, Susan P Foy, Andrew Conroy, Michael C Yi, Christine Shieh, William Lu, Katharine Heeringa, Yan Ma, Shahab Chizari, Melissa J Pilling, Marc Ting, Ramya Tunuguntla, Salemiz Sandoval, Robert Moot, Theresa Hunter, Sidi Zhao, Justin D Saco, Ivan Perez-Garcilazo, Egmidio Medina, Agustin Vega-Crespo, Ignacio Baselga-Carretero, Gabriel Abril-Rodriguez, Grace Cherry, Deborah J Wong, Jasreet Hundal, Bartosz Chmielowski, Daniel E Speiser, Michael T Bethune, Xiaoyan R Bao, Alena Gros, Malachi Griffith, Malachi Griffith, James R Heath, Alex Franzusoff, Stefanie J Mandl, Antoni Ribas
Neoantigen-targeted CD8 + T cell responses with PD-1 blockade therapy. Nature 615 (7953) (2023)
Cristina Puig-Saus, Barbara Sennino, Songming Peng, Clifford L Wang, Zheng Pan, Benjamin Yuen, Bhamini Purandare, Duo An, Boi B Quach, Diana Nguyen, Huiming Xia, Sameeha Jilani, Kevin Shao, Claire McHugh, John Greer, Phillip Peabody, Saparya Nayak, Jonathan Hoover, Sara Said, Kyle Jacoby, Olivier Dalmas, Susan P Foy, Andrew Conroy, Michael C Yi, Christine Shieh, William Lu, Katharine Heeringa, Yan Ma, Shahab Chizari, Melissa J Pilling, Marc Ting, Ramya Tunuguntla, Salemiz Sandoval, Robert Moot, Theresa Hunter, Sidi Zhao, Justin D Saco, Ivan Perez-Garcilazo, Egmidio Medina, Agustin Vega-Crespo, Ignacio Baselga-Carretero, Gabriel Abril-Rodriguez, Grace Cherry, Deborah J Wong, Jasreet Hundal, Bartosz Chmielowski, Daniel E Speiser, Michael T Bethune, Xiaoyan R Bao, Alena Gros, Malachi Griffith, Malachi Griffith, James R Heath, Alex Franzusoff, Stefanie J Mandl, Antoni Ribas
Neoantigen-targeted CD8 + T cell responses with PD-1 blockade therapy. Nature (2023)
William Chour, Jongchan Choi, Jingyi Xie, Mary E Chaffee, Thomas M Schmitt, Kathryn Finton, Diana C DeLucia, Alexander M Xu, Yapeng Su, Daniel G Chen, Rongyu Zhang, Dan Yuan, Sunga Hong, Alphonsus H C Ng, Jonah Z Butler, Rick A Edmark, Lesley C Jones, Kim M Murray, Songming Peng, Guideng Li, Roland K Strong, John K Lee, Jason D Goldman, Philip D Greenberg, James R Heath
Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis. Communications biology 6 (1) (2023)
Avishai Shemesh, Yapeng Su, Daniel R Calabrese, Daniel G Chen, Janice S Arakawa-Hoyt, Kole T Roybal, James R Heath, John R Greenland, Lewis L Lanier
Diminished cell proliferation promotes natural killer cell adaptive-like phenotype by limiting FcεRIγ expression. The Journal of experimental medicine 219 (11) (2022)
Jing Li, Maxim E Zaslavsky, Yapeng Su, Jing Guo, Michael J Sikora, Vincent van Unen, Asbjørn O Christophersen, Shin-Heng Chiou, Liang Chen, Jiefu Li, Xuhuai Ji, Julie Wilhelmy, Alana M McSween, Brad A Palanski, Venkata Vamsee Aditya Mallajosyula, Nathan A Bracey, Gopal Krishna R Dhondalay, Kartik Bhamidipati, Joy Pai, Lucas B Kipp, Jeffrey E Dunn, Stephen L Hauser, Jorge R Oksenberg, Ansuman T Satpathy, William H Robinson, Cornelia L Dekker, Lars M Steinmetz, Chaitan Khosla, Paul J Utz, Ludvig M Sollid, Yueh-Hsiu Chien, James R Heath, Nielsen Q Fernandez-Becker, Kari Christine Nadeau, Naresha Saligrama, Mark M Davis
KIR + CD8 + T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19. Science (New York, N.Y.) 376 (6590) (2022)
Maxim E Zaslavsky, Nikhil Ram-Mohan, Joel M Guthridge, Joan T Merrill, Jason D Goldman, Ji-Yeun Lee, Krishna M Roskin, Charlotte Cunningham-Rundles, M Anthony Moody, Barton F Haynes, Benjamin A Pinsky, James R Heath, Judith A James, Samuel Yang, Catherine A Blish, Robert Tibshirani, Anshul Kundaje, Scott D Boyd
Disease diagnostics using machine learning of immune receptors. bioRxiv : the preprint server for biology (2022)
Susan P Foy, Kyle Jacoby, Daniela A Bota, Theresa Hunter, Zheng Pan, Eric Stawiski, Yan Ma, William Lu, Songming Peng, Clifford L Wang, Benjamin Yuen, Olivier Dalmas, Katharine Heeringa, Barbara Sennino, Andy Conroy, Michael T Bethune, Ines Mende, William White, Monica Kukreja, Swetha Gunturu, Emily Humphrey, Adeel Hussaini, Duo An, Adam J Litterman, Boi Bryant Quach, Alphonsus H C Ng, Yue Lu, Chad Smith, Katie M Campbell, Daniel Anaya, Lindsey Skrdlant, Eva Yi-Hsuan Huang, Ventura Mendoza, Jyoti Mathur, Luke Dengler, Bhamini Purandare, Robert Moot, Michael C Yi, Roel Funke, Alison Sibley, Todd Stallings-Schmitt, David Y Oh, Bartosz Chmielowski, Mehrdad Abedi, Yuan Yuan, Jeffrey A Sosman, Sylvia M Lee, Adam J Schoenfeld, David Baltimore, James R Heath, Alex Franzusoff, Antoni Ribas, Arati V Rao, Stefanie J Mandl
Non-viral precision T cell receptor replacement for personalized cell therapy. Nature (2022)
James R Heath, William Chour, Jongchan Choi, Jingyi Xie, Mary Chaffee, Thomas Schmitt, Kathryn Finton, Diana C DeLucia, Alexander M Xu, Yapeng Su, Daniel G Chen, Rongyu Zhang, Dan Yuan, Sunga Hong, Alphonsus Ng, Jonah Butler, Rick Edmark, Lesley Jones, Kim Murray, Songming Peng, Guideng Li, Roland Strong, John K Lee, Jason D Goldman, Philip D Greenberg
Large libraries of single-chain trimer peptide-MHCs enable rapid antigen-specific CD8+ T cell discovery and analysis. Research square (2022)
Jihoon W Lee, Yapeng Su, Priyanka Baloni, Daniel G Chen, Ana Jimena Pavlovitch-Bedzyk, Dan Yuan, Venkata R Duvvuri, Rachel H Ng, Jongchan Choi, Jingyi Xie, Rongyu Zhang, Kim Murray, Sergey Kornilov, Brett Smith, Andrew T Magis, Dave S B Hoon, Jennifer J Hadlock, Jason D Goldman, Nathan D Price, Raphaël Gottardo, Mark M Davis, Leroy Hood, Philip D Greenberg, James R Heath
Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19. Nature biotechnology (2021)
Yue Lu, Alphonsus H C Ng, Frances E Chow, Richard G Everson, Beth A Helmink, Michael T Tetzlaff, Rohit Thakur, Jennifer A Wargo, Timothy F Cloughesy, Robert M Prins, James R Heath
Resolution of tissue signatures of therapy response in patients with recurrent GBM treated with neoadjuvant anti-PD1. Nature communications 12 (1) (2021)
Jing Li, Maxim E Zaslavsky, Yapeng Su, Michael J Sikora, Vincent van Unen, Asbjørn O Christophersen, Shin-Heng Chiou, Liang Chen, Jiefu Li, Xuhuai Ji, Julie Wilhelmy, Alana M McSween, Brad A Palanski, Venkata Vamsee Aditya Mallajosyula, Gopal Krishna R Dhondalay, Kartik Bhamidipati, Joy Pai, Lucas B Kipp, Jeffrey E Dunn, Stephen L Hauser, Jorge R Oksenberg, Ansuman T Satpathy, William H Robinson, Lars M Steinmetz, Chaitan Khosla, Paul J Utz, Ludvig M Sollid, James R Heath, Nielsen Q Fernandez-Becker, Kari Christine Nadeau, Naresha Saligrama, Mark M Davis
Human KIR + CD8 + T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19. bioRxiv : the preprint server for biology (2021)
Yapeng Su, Melissa E Ko, Hanjun Cheng, Ronghui Zhu, Min Xue, Jessica K Wang, Jihoon W Lee, Luke Frankiw, Alexander Xu, Stephanie Wong, Lidia Robert, Kaitlyn Takata, Dan Yuan, Yue Lu, Sui Huang, Antoni Ribas, Raphael Levine, Garry P Nolan, Wei Wei, Sylvia K Plevritis, Guideng Li, David Baltimore, James R Heath
Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line. Nature communications 11 (1) (2020)
Matthew N Idso, Ajay Suresh Akhade, Mario L Arrieta-Ortiz, Bert T Lai, Vivek Srinivas, James P Hopkins, Ana Oliveira Gomes, Naeha Subramanian, Nitin Baliga, James R Heath
Antibody-recruiting protein-catalyzed capture agents to combat antibiotic-resistant bacteria. Chemical science 11 (11) (2020)
Jiajun Du, Yapeng Su, Chenxi Qian, Dan Yuan, Kun Miao, Dongkwan Lee, Alphonsus H C Ng, Reto S Wijker, Antoni Ribas, Raphael D Levine, James R Heath, Lu Wei
Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells. Nature communications 11 (1) (2020)
Heather D Agnew, Matthew B Coppock, Matthew N Idso, Bert T Lai, Jingxin Liang, Amy M McCarthy-Torrens, Carmen M Warren, James R Heath
Protein-Catalyzed Capture Agents. Chemical reviews 119 (17) (2019)
Jingxin Liang, David N Bunck, Anvita Mishra, Sunga Hong, Matthew N Idso, James R Heath
Inhibition of heme sequestration of histidine-rich protein 2 using multiple epitope-targeted peptides. Journal of peptide science : an official publication of the European Peptide Society 25 (9) (2019)
David N Bunck, Beatriz Atsavapranee, Anna K Museth, David VanderVelde, James R Heath
Modulating the Folding Landscape of Superoxide Dismutase 1 with Targeted Molecular Binders. Angewandte Chemie (International ed. in English) 57 (21) (2018)
Jing Zhou, Michael T Bethune, Natalia Malkova, Alexander M Sutherland, Begonya Comin-Anduix, Yapeng Su, David Baltimore, Antoni Ribas, James R Heath
A kinetic investigation of interacting, stimulated T cells identifies conditions for rapid functional enhancement, minimal phenotype differentiation, and improved adoptive cell transfer tumor eradication. PloS one 13 (1) (2018)

James R Heath.css-eqlu8i{font-size:small;padding-left:4px;} (James Heath)

Publication Activity (10 Years)

Top Topics

Top Venues

James R Heath (James Heath)