Amy Shen

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 13

Top Topics

Klebsiella Pneumoniae

Top Venues

Biotechnology progress

This page only lists publications with an associated author ORCID identifier.

Publications

Kavya Ganapathy, Cynthia Lam, Joni Tsukuda, Alyssa Sargon, Adrian Nava, Peter Harms, Amy Shen, Gavin Barnard, Shahram Misaghi
SPEED-MODE cell line development (CLD): Reducing Chinese hamster ovary (CHO) CLD timelines via earlier suspension adaptation and maximizing time spent in the exponential growth phase. Biotechnology progress (2024)
Gavin C Barnard, Michelle Zhou, Amy Shen, Inn H Yuk, Michael W Laird
Utilizing targeted integration CHO pools to potentially accelerate the GMP manufacturing of monoclonal and bispecific antibodies. Biotechnology progress (2023)
Cynthia Lam, Joseph Carver, Domingos Ng, Dejin Zhan, Danming Tang, Thara Kandamkalam, Brad Snedecor, Gavin Barnard, Amy Shen, Shahram Misaghi
Combining regulated and constitutive protein expression significantly boosts protein expression by increasing productivity without affecting CHO cell growth. Biotechnology progress (2023)
Cynthia Lam, Joseph Carver, Domingos Ng, Dejin Zhan, Danming Tang, Thara Kandamkalam, Brad Snedecor, Gavin Barnard, Amy Shen, Shahram Misaghi
Combining Regulated and Constitutive Protein Expression Significantly Boosts Protein Expression by Increasing Productivity without Affecting CHO Cell Growth. Biotechnology progress (2023)
Danming Tang, Jane Gunson, Eric Tran, Cynthia Lam, Amy Shen, Brad Snedecor, Gavin Barnard, Shahram Misaghi
Expressing antigen binding fragments with high titers in a targeted integration CHO host by optimizing expression vector gene copy numbers and position: A case study. Biotechnology progress 38 (6) (2022)
Danming Tang, Jane Gunson, Eric Tran, Cynthia Lam, Amy Shen, Brad Snedecor, Gavin Barnard, Shahram Misaghi
Expressing antigen binding fragments with high titers in a targeted integration CHO host by optimizing expression vector gene copy numbers and position: A case study. Biotechnology progress 38 (6) (2022)
Danming Tang, Jane Gunson, Eric Tran, Cynthia Lam, Amy Shen, Brad Snedecor, Gavin Barnard, Shahram Misaghi
Expressing antigen binding fragments with high titers in a targeted integration CHO host by optimizing expression vector gene copy numbers and position: A case study. Biotechnology progress 38 (6) (2022)
Danming Tang, Jane Gunson, Eric Tran, Cynthia Lam, Amy Shen, Brad Snedecor, Gavin Barnard, Shahram Misaghi
Expressing antigen binding fragments with high titers in a targeted integration CHO host by optimizing expression vector gene copy numbers and position: A case study. Biotechnology progress 38 (6) (2022)
Joseph Carver, Marie Kern, Peggy Ko, Midori Greenwood-Goodwin, X Christopher Yu, Dana Duan, Danming Tang, Shahram Misaghi, Simon Auslaender, Ben Haley, Inn H Yuk, Amy Shen
A ribonucleoprotein-based decaplex CRISPR/Cas9 knockout strategy for CHO host engineering. Biotechnology progress (2021)
Domingos Ng, Meixia Zhou, Dejin Zhan, Shirley Yip, Peggy Ko, Mandy Yim, Zora Modrusan, John Joly, Brad Snedecor, Michael W Laird, Amy Shen
Development of a targeted integration Chinese hamster ovary host directly targeting either one or two vectors simultaneously to a single locus using the Cre/Lox recombinase-mediated cassette exchange system. Biotechnology progress 37 (4) (2021)
Joe Carver, Domingos Ng, Michelle Zhou, Peggy Ko, Dejin Zhan, Mandy Yim, David Shaw, Brad Snedecor, Michael W Laird, Steven Lang, Amy Shen, Zhilan Hu
Maximizing antibody production in a targeted integration host by optimization of subunit gene dosage and position. Biotechnology progress 36 (4) (2020)
Zhilan Hu, Wendy Hsu, Abby Pynn, Domingos Ng, Donna Quicho, Yilma Adem, Zephie Kwong, Brad Mauger, John Joly, Bradley Snedecor, Michael W Laird, Dana C Andersen, Amy Shen
A strategy to accelerate protein production from a pool of clones in Chinese hamster ovary cells for toxicology studies. Biotechnology progress 33 (6) (2017)
Peggy Ko, Shahram Misaghi, Zhilan Hu, Dejin Zhan, Joni Tsukuda, Mandy Yim, Mark Sanford, David Shaw, Masaru Shiratori, Brad Snedecor, Michael Laird, Amy Shen
Probing the importance of clonality: Single cell subcloning of clonally derived CHO cell lines yields widely diverse clones differing in growth, productivity, and product quality. Biotechnology progress 34 (3) (2017)