Anne Houdusse

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 34

Top Topics

Plasmodium Falciparum

Hypertrophic Cardiomyopathy

Endoplasmic Reticulum

Single Molecule

Top Venues

Nature communications

PLoS computational biology

Nature cardiovascular research

This page only lists publications with an associated author ORCID identifier.

Publications

James J Hartman, Darren T Hwee, Julien Robert-Paganin, Chihyuan Chuang, Eva R Chin, Samantha Edell, Ken H Lee, Roshni Madhvani, Preeti Paliwal, Julien Pernier, Saswata Sankar Sarkar, Julia Schaletzky, Kristine Schauer, Khanha D Taheri, Jingying Wang, Eddie Wehri, Yangsong Wu, Anne Houdusse, Bradley P Morgan, Fady I Malik
Aficamten is a small-molecule cardiac myosin inhibitor designed to treat hypertrophic cardiomyopathy. Nature cardiovascular research 3 (8) (2024)
Florian E C Blanc, Anne Houdusse, Marco Cecchini
A weak coupling mechanism for the early steps of the recovery stroke of myosin VI: A free energy simulation and string method analysis. PLoS computational biology 20 (4) (2024)
James J Hartman, Darren T Hwee, Julien Robert-Paganin, Chihyuan Chuang, Eva R Chin, Samantha Edell, Ken H Lee, Roshni Madhvani, Preeti Paliwal, Julien Pernier, Saswata Sankar Sarkar, Julia Schaletzky, Kristine Schauer, Khanha D Taheri, Jingying Wang, Eddie Wehri, Yangsong Wu, Anne Houdusse, Bradley P Morgan, Fady I Malik
Aficamten is a small-molecule cardiac myosin inhibitor designed to treat hypertrophic cardiomyopathy. Nature cardiovascular research 3 (8) (2024)
Daniel Auguin, Julien Robert-Paganin, Stéphane Réty, Carlos Kikuti, Amandine David, Gabriele Theumer, Arndt W Schmidt, Hans-Joachim Knölker, Anne Houdusse
Omecamtiv mecarbil and Mavacamten target the same myosin pocket despite opposite effects in heart contraction. Nature communications 15 (1) (2024)
James A Spudich, Neha Nandwani, Julien Robert-Paganin, Anne Houdusse, Kathleen M Ruppel
Reassessing the unifying hypothesis for hypercontractility caused by myosin mutations in hypertrophic cardiomyopathy. The EMBO journal (2024)
Daniel Auguin, Julien Robert-Paganin, Stéphane Réty, Carlos Kikuti, Amandine David, Gabriele Theumer, Arndt W Schmidt, Hans-Joachim Knölker, Anne Houdusse
Omecamtiv mecarbil and Mavacamten target the same myosin pocket despite opposite effects in heart contraction. Nature communications 15 (1) (2024)
Florian E C Blanc, Anne Houdusse, Marco Cecchini
A weak coupling mechanism for the early steps of the recovery stroke of myosin VI: A free energy simulation and string method analysis. PLoS computational biology 20 (4) (2024)
Daniel Auguin, Julien Robert-Paganin, Stéphane Réty, Carlos Kikuti, Amandine David, Gabriele Theumer, Arndt W Schmidt, Hans-Joachim Knölker, Anne Houdusse
Omecamtiv mecarbil and Mavacamten target the same myosin pocket despite opposite effects in heart contraction. Nature communications 15 (1) (2024)
James J Hartman, Darren T Hwee, Julien Robert-Paganin, Chihyuan Chuang, Eva R Chin, Samantha Edell, Ken H Lee, Roshni Madhvani, Preeti Paliwal, Julien Pernier, Saswata Sankar Sarkar, Julia Schaletzky, Kristine Schauer, Khanha D Taheri, Jingying Wang, Eddie Wehri, Yangsong Wu, Anne Houdusse, Bradley P Morgan, Fady I Malik
Aficamten is a small-molecule cardiac myosin inhibitor designed to treat hypertrophic cardiomyopathy. Nature cardiovascular research 3 (8) (2024)
Florian E C Blanc, Anne Houdusse, Marco Cecchini
A weak coupling mechanism for the early steps of the recovery stroke of myosin VI: A free energy simulation and string method analysis. PLoS computational biology 20 (4) (2024)
Florian E C Blanc, Anne Houdusse, Marco Cecchini
A weak coupling mechanism for the early steps of the recovery stroke of myosin VI: A free energy simulation and string method analysis. PLoS computational biology 20 (4) (2024)
Daniel Auguin, Julien Robert-Paganin, Stéphane Réty, Carlos Kikuti, Amandine David, Gabriele Theumer, Arndt W Schmidt, Hans-Joachim Knölker, Anne Houdusse
Omecamtiv mecarbil and Mavacamten target the same myosin pocket despite opposite effects in heart contraction. Nature communications 15 (1) (2024)
Alessandro Grinzato, Daniel Auguin, Carlos Kikuti, Neha Nandwani, Dihia Moussaoui, Divya Pathak, Eaazhisai Kandiah, Kathleen M Ruppel, James A Spudich, Anne Houdusse, Julien Robert-Paganin
Cryo-EM structure of the folded-back state of human β-cardiac myosin. Nature communications 14 (1) (2023)
Alessandro Grinzato, Daniel Auguin, Carlos Kikuti, Neha Nandwani, Dihia Moussaoui, Divya Pathak, Eaazhisai Kandiah, Kathleen M Ruppel, James A Spudich, Anne Houdusse, Julien Robert-Paganin
Cryo-EM structure of the folded-back state of human β-cardiac myosin. bioRxiv : the preprint server for biology (2023)
Alessandro Grinzato, Daniel Auguin, Carlos Kikuti, Neha Nandwani, Dihia Moussaoui, Divya Pathak, Eaazhisai Kandiah, Kathleen M Ruppel, James A Spudich, Anne Houdusse, Julien Robert-Paganin
Cryo-EM structure of the folded-back state of human β-cardiac myosin. bioRxiv : the preprint server for biology (2023)
Dihia Moussaoui, James P Robblee, Julien Robert-Paganin, Daniel Auguin, Fabio Fisher, Patricia M Fagnant, Jill E Macfarlane, Julia Schaletzky, Eddie Wehri, Christoph Mueller-Dieckmann, Jake Baum, Kathleen M Trybus, Anne Houdusse
Mechanism of small molecule inhibition of Plasmodium falciparum myosin A informs antimalarial drug design. Nature communications 14 (1) (2023)
Fanomezana Moutse Ranaivoson, Vincent Crozet, Matthieu P M H Benoit, Amna Abdalla Mohammed Khalid, Carlos Kikuti, Helena Sirkia, Ahmed El Marjou, Stéphanie Miserey-Lenkei, Ana B Asenjo, Hernando Sosa, Christoph F Schmidt, Steven S Rosenfeld, Anne Houdusse
Nucleotide-free structures of KIF20A illuminate atypical mechanochemistry in this kinesin-6. Open biology 13 (9) (2023)
Daniel Auguin, Julien Robert-Paganin, Stéphane Réty, Carlos Kikuti, Amandine David, Gabriele Theumer, Arndt W Schmidt, Hans-Joachim Knölker, Anne Houdusse
Omecamtiv mecarbil and Mavacamten target the same myosin pocket despite antagonistic effects in heart contraction. bioRxiv : the preprint server for biology (2023)
Louise Canon, Carlos Kikuti, Vicente Jose Planelles-Herrero, Tianming Lin, Franck Mayeux, Helena Sirkia, Young Il Lee, Leila Heidsieck, Léonid Velikovsky, Amandine David, Xiaoyan Liu, Dihia Moussaoui, Emma Forest, Peter Höök, Karl J Petersen, Tomos E Morgan, Aurélie Di Cicco, Julia Sirés-Campos, Emmanuel Derivery, Daniel Lévy, Cédric Delevoye, H Lee Sweeney, Anne Houdusse
How myosin VI traps its off-state, is activated and dimerizes. Nature communications 14 (1) (2023)
Lara Katharina Krüger, Matthieu Gélin, Liang Ji, Carlos Kikuti, Anne Houdusse, Manuel Théry, Laurent Blanchoin, Phong Thanh Tran
Kinesin-6 Klp9 orchestrates spindle elongation by regulating microtubule sliding and growth. eLife 10 (2021)
Anne Houdusse
Biological nanomotors, driving forces of life. Comptes rendus biologies 343 (4) (2021)
Sabrina Pospich, H Lee Sweeney, Anne Houdusse, Stefan Raunser
High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. eLife 10 (2021)
Julien Robert-Paganin, Xiao-Ping Xu, Mark F Swift, Daniel Auguin, James P Robblee, Hailong Lu, Patricia M Fagnant, Elena B Krementsova, Kathleen M Trybus, Anne Houdusse, Niels Volkmann, Dorit Hanein
The actomyosin interface contains an evolutionary conserved core and an ancillary interface involved in specificity. Nature communications 12 (1) (2021)
Ashley L Arthur, Amy Crawford, Anne Houdusse, Margaret A Titus
VASP-mediated actin dynamics activate and recruit a filopodia myosin. eLife 10 (2021)
Dihia Moussaoui, James P Robblee, Daniel Auguin, Elena B Krementsova, Silvia Haase, Thomas C A Blake, Jake Baum, Julien Robert-Paganin, Kathleen M Trybus, Anne Houdusse
Full-length Plasmodium falciparum myosin A and essential light chain PfELC structures provide new anti-malarial targets. eLife 9 (2020)
Julien Robert-Paganin, James P Robblee, Daniel Auguin, Thomas C A Blake, Carol S Bookwalter, Elena B Krementsova, Dihia Moussaoui, Michael J Previs, Guillaume Jousset, Jake Baum, Kathleen M Trybus, Anne Houdusse
Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism. Nature communications 10 (1) (2019)
Ashley L Arthur, Livia D Songster, Helena Sirkia, Akash Bhattacharya, Carlos Kikuti, Fernanda Pires Borrega, Anne Houdusse, Margaret A Titus
Optimized filopodia formation requires myosin tail domain cooperation. Proceedings of the National Academy of Sciences of the United States of America 116 (44) (2019)
Julien Robert-Paganin, Olena Pylypenko, Carlos Kikuti, H Lee Sweeney, Anne Houdusse
Force Generation by Myosin Motors: A Structural Perspective. Chemical reviews 120 (1) (2019)
Florian E C Blanc, Tatiana Isabet, Hannah Benisty, H Lee Sweeney, Marco Cecchini, Anne Houdusse
An intermediate along the recovery stroke of myosin VI revealed by X-ray crystallography and molecular dynamics. Proceedings of the National Academy of Sciences of the United States of America 115 (24) (2018)
Julien Robert-Paganin, Daniel Auguin, Anne Houdusse
Hypertrophic cardiomyopathy disease results from disparate impairments of cardiac myosin function and auto-inhibition. Nature communications 9 (1) (2018)
Sara Bizzotto, Ana Uzquiano, Florent Dingli, Dmitry Ershov, Anne Houllier, Guillaume Arras, Mark Richards, Damarys Loew, Nicolas Minc, Alexandre Croquelois, Anne Houdusse, Fiona Francis
Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex. Scientific reports 7 (1) (2017)
I-Mei Yu, Vicente J Planelles-Herrero, Yannick Sourigues, Dihia Moussaoui, Helena Sirkia, Carlos Kikuti, David Stroebel, Margaret A Titus, Anne Houdusse
Myosin 7 and its adaptors link cadherins to actin. Nature communications 8 (2017)
Vicente Jose Planelles-Herrero, James J Hartman, Julien Robert-Paganin, Fady I Malik, Anne Houdusse
Mechanistic and structural basis for activation of cardiac myosin force production by omecamtiv mecarbil. Nature communications 8 (1) (2017)
Stéphanie Miserey-Lenkei, Hugo Bousquet, Olena Pylypenko, Sabine Bardin, Ariane Dimitrov, Gaëlle Bressanelli, Raja Bonifay, Vincent Fraisier, Catherine Guillou, Cécile Bougeret, Anne Houdusse, Arnaud Echard, Bruno Goud
Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions. Nature communications 8 (1) (2017)