Anthony Maxwell

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 37

Top Venues

Journal of medicinal chemistry

eLife

NAR genomics and bioinformatics

BMC research notes

John Innes Centre

University of Bristol (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

John Innes Centre Aug 01 2000

United Kingdom

Project Leader :: Biological Chemistry

University of Leicester Feb 01 1986 - Jul 31 2000

United Kingdom

Lecturer :: Biochemistry

National Institutes of Health Feb 01 1982 - Jan 31 1986

United States

Postdoc :: NIADDK

University of Bristol Aug 01 1981 - Jan 31 1982

United Kingdom

Research Assistant :: Biochemistry

Education History

University of Bristol Aug 01 1978 - Jul 31 1981

United Kingdom

PHD :: Biochemistry

Publications

Adam M B Allen, Anthony Maxwell
Phylogenetic distribution of DNA topoisomerase VI and its distinction from SPO11. NAR genomics and bioinformatics 6 (3) (2024)
Thomas R M Germe, Natassja G Bush, Victoria M Baskerville, Dominik Saman, Justin L P Benesch, Anthony Maxwell
Rapid, DNA-induced interface swapping by DNA gyrase. eLife 12 (2024)
Adam M B Allen, Anthony Maxwell
Phylogenetic distribution of DNA topoisomerase VI and its distinction from SPO11. NAR genomics and bioinformatics 6 (3) (2024)
Thomas R M Germe, Natassja G Bush, Victoria M Baskerville, Dominik Saman, Justin L P Benesch, Anthony Maxwell
Rapid, DNA-induced interface swapping by DNA gyrase. eLife 12 (2024)
Thomas R M Germe, Natassja G Bush, Victoria M Baskerville, Dominik Saman, Justin L P Benesch, Anthony Maxwell
Rapid, DNA-induced interface swapping by DNA gyrase. eLife 12 (2024)
Thomas R M Germe, Natassja G Bush, Victoria M Baskerville, Dominik Saman, Justin L P Benesch, Anthony Maxwell
Rapid, DNA-induced interface swapping by DNA gyrase. eLife 12 (2024)
Thomas R M Germe, Natassja G Bush, Victoria M Baskerville, Dominik Saman, Justin L P Benesch, Anthony Maxwell
Rapid, DNA-induced interface swapping by DNA gyrase. eLife 12 (2024)
Thomas R M Germe, Natassja G Bush, Victoria M Baskerville, Dominik Saman, Justin L P Benesch, Anthony Maxwell
Rapid, DNA-induced interface swapping by DNA gyrase. eLife 12 (2024)
Thomas R M Germe, Natassja G Bush, Victoria M Baskerville, Dominik Saman, Justin L P Benesch, Anthony Maxwell
Rapid, DNA-induced interface swapping by DNA gyrase. eLife 12 (2024)
Ian L Morgan, Shannon J McKie, Rachel Kim, Yeonee Seol, Jing Xu, Gabor M Harami, Anthony Maxwell, Keir C Neuman
Highly sensitive mapping of in vitro type II topoisomerase DNA cleavage sites with SHAN-seq. Nucleic acids research (2024)
Ian L Morgan, Shannon J McKie, Rachel Kim, Yeonee Seol, Jing Xu, Gabor M Harami, Anthony Maxwell, Keir C Neuman
Highly sensitive mapping of in vitro type II topoisomerase DNA cleavage sites with SHAN-seq. Nucleic acids research (2024)
Adam M B Allen, Anthony Maxwell
Phylogenetic distribution of DNA topoisomerase VI and its distinction from SPO11. NAR genomics and bioinformatics 6 (3) (2024)
Thomas R M Germe, Natassja G Bush, Victoria M Baskerville, Dominik Saman, Justin L P Benesch, Anthony Maxwell
Rapid, DNA-induced interface swapping by DNA gyrase. eLife 12 (2024)
Martina Durcik, Andrej Emanuel Cotman, Žan Toplak, Štefan Možina, Žiga Skok, Petra Eva Szili, Márton Czikkely, Elvin Maharramov, Thu Hien Vu, Maria Vittoria Piras, Nace Zidar, Janez Ilaš, Anamarija Zega, Jurij Trontelj, Luis A Pardo, Diarmaid Hughes, Douglas L Huseby, Talía Berruga Fernández, Sha Cao, Ivailo Simoff, Richard Svensson, Sergiy V Korol, Zhe Jin, Francisca Vicente, Maria C Ramos, Julia E A Mundy, Anthony Maxwell, Clare E M Stevenson, David M Lawson, Björn Glinghammar, Eva Sjöström, Martin Bohlin, Joanna Oreskär, Sofie Alvér, Guido V Janssen, Geert Jan Sterk, Danijel Kikelj, Csaba Pal, Tihomir Tomašič, Lucija Peterlin Mašič
New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus . Journal of medicinal chemistry 66 (6) (2023)
Andrej Emanuel Cotman, Martina Durcik, Davide Benedetto Tiz, Federica Fulgheri, Daniela Secci, Maša Sterle, Štefan Možina, Žiga Skok, Nace Zidar, Anamarija Zega, Janez Ilaš, Lucija Peterlin Mašič, Tihomir Tomašič, Diarmaid Hughes, Douglas L Huseby, Sha Cao, Linnéa Garoff, Talía Berruga Fernández, Paraskevi Giachou, Lisa Crone, Ivailo Simoff, Richard Svensson, Bryndis Birnir, Sergiy V Korol, Zhe Jin, Francisca Vicente, Maria C Ramos, Mercedes de la Cruz, Björn Glinghammar, Lena Lenhammar, Sara R Henderson, Julia E A Mundy, Anthony Maxwell, Clare E M Stevenson, David M Lawson, Guido V Janssen, Geert Jan Sterk, Danijel Kikelj
Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa . Journal of medicinal chemistry 66 (2) (2023)
Martina Durcik, Andrej Emanuel Cotman, Žan Toplak, Štefan Možina, Žiga Skok, Petra Eva Szili, Márton Czikkely, Elvin Maharramov, Thu Hien Vu, Maria Vittoria Piras, Nace Zidar, Janez Ilaš, Anamarija Zega, Jurij Trontelj, Luis A Pardo, Diarmaid Hughes, Douglas L Huseby, Talía Berruga Fernández, Sha Cao, Ivailo Simoff, Richard Svensson, Sergiy V Korol, Zhe Jin, Francisca Vicente, Maria C Ramos, Julia E A Mundy, Anthony Maxwell, Clare E M Stevenson, David M Lawson, Björn Glinghammar, Eva Sjöström, Martin Bohlin, Joanna Oreskär, Sofie Alvér, Guido V Janssen, Geert Jan Sterk, Danijel Kikelj, Csaba Pal, Tihomir Tomašič, Lucija Peterlin Mašič
New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus . Journal of medicinal chemistry 66 (6) (2023)
Maša Sterle, Martina Durcik, Clare E M Stevenson, Sara R Henderson, Petra Eva Szili, Marton Czikkely, David M Lawson, Anthony Maxwell, Dominique Cahard, Danijel Kikelj, Nace Zidar, Csaba Pal, Lucija Peterlin Mašič, Janez Ilaš, Tihomir Tomašič, Andrej Emanuel Cotman, Anamarija Zega
Exploring the 5-Substituted 2-Aminobenzothiazole-Based DNA Gyrase B Inhibitors Active against ESKAPE Pathogens. ACS omega 8 (27) (2023)
Andrej Emanuel Cotman, Martina Durcik, Davide Benedetto Tiz, Federica Fulgheri, Daniela Secci, Maša Sterle, Štefan Možina, Žiga Skok, Nace Zidar, Anamarija Zega, Janez Ilaš, Lucija Peterlin Mašič, Tihomir Tomašič, Diarmaid Hughes, Douglas L Huseby, Sha Cao, Linnéa Garoff, Talía Berruga Fernández, Paraskevi Giachou, Lisa Crone, Ivailo Simoff, Richard Svensson, Bryndis Birnir, Sergiy V Korol, Zhe Jin, Francisca Vicente, Maria C Ramos, Mercedes de la Cruz, Björn Glinghammar, Lena Lenhammar, Sara R Henderson, Julia E A Mundy, Anthony Maxwell, Clare E M Stevenson, David M Lawson, Guido V Janssen, Geert Jan Sterk, Danijel Kikelj
Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa . Journal of medicinal chemistry 66 (2) (2023)
Andrej Emanuel Cotman, Martina Durcik, Davide Benedetto Tiz, Federica Fulgheri, Daniela Secci, Maša Sterle, Štefan Možina, Žiga Skok, Nace Zidar, Anamarija Zega, Janez Ilaš, Lucija Peterlin Mašič, Tihomir Tomašič, Diarmaid Hughes, Douglas L Huseby, Sha Cao, Linnéa Garoff, Talía Berruga Fernández, Paraskevi Giachou, Lisa Crone, Ivailo Simoff, Richard Svensson, Bryndis Birnir, Sergiy V Korol, Zhe Jin, Francisca Vicente, Maria C Ramos, Mercedes de la Cruz, Björn Glinghammar, Lena Lenhammar, Sara R Henderson, Julia E A Mundy, Anthony Maxwell, Clare E M Stevenson, David M Lawson, Guido V Janssen, Geert Jan Sterk, Danijel Kikelj
Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa . Journal of medicinal chemistry 66 (2) (2023)
Andrej Emanuel Cotman, Martina Durcik, Davide Benedetto Tiz, Federica Fulgheri, Daniela Secci, Maša Sterle, Štefan Možina, Žiga Skok, Nace Zidar, Anamarija Zega, Janez Ilaš, Lucija Peterlin Mašič, Tihomir Tomašič, Diarmaid Hughes, Douglas L Huseby, Sha Cao, Linnéa Garoff, Talía Berruga Fernández, Paraskevi Giachou, Lisa Crone, Ivailo Simoff, Richard Svensson, Bryndis Birnir, Sergiy V Korol, Zhe Jin, Francisca Vicente, Maria C Ramos, Mercedes de la Cruz, Björn Glinghammar, Lena Lenhammar, Sara R Henderson, Julia E A Mundy, Anthony Maxwell, Clare E M Stevenson, David M Lawson, Guido V Janssen, Geert Jan Sterk, Danijel Kikelj
Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa . Journal of medicinal chemistry (2023)
Martina Durcik, Andrej Emanuel Cotman, Žan Toplak, Štefan Možina, Žiga Skok, Petra Eva Szili, Márton Czikkely, Elvin Maharramov, Thu Hien Vu, Maria Vittoria Piras, Nace Zidar, Janez Ilaš, Anamarija Zega, Jurij Trontelj, Luis A Pardo, Diarmaid Hughes, Douglas L Huseby, Talía Berruga Fernández, Sha Cao, Ivailo Simoff, Richard Svensson, Sergiy V Korol, Zhe Jin, Francisca Vicente, Maria C Ramos, Julia E A Mundy, Anthony Maxwell, Clare E M Stevenson, David M Lawson, Björn Glinghammar, Eva Sjöström, Martin Bohlin, Joanna Oreskär, Sofie Alvér, Guido V Janssen, Geert Jan Sterk, Danijel Kikelj, Csaba Pal, Tihomir Tomašič, Lucija Peterlin Mašič
New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus . Journal of medicinal chemistry (2023)
Andrej Emanuel Cotman, Martina Durcik, Davide Benedetto Tiz, Federica Fulgheri, Daniela Secci, Maša Sterle, Štefan Možina, Žiga Skok, Nace Zidar, Anamarija Zega, Janez Ilaš, Lucija Peterlin Mašič, Tihomir Tomašič, Diarmaid Hughes, Douglas L Huseby, Sha Cao, Linnéa Garoff, Talía Berruga Fernández, Paraskevi Giachou, Lisa Crone, Ivailo Simoff, Richard Svensson, Bryndis Birnir, Sergiy V Korol, Zhe Jin, Francisca Vicente, Maria C Ramos, Mercedes de la Cruz, Björn Glinghammar, Lena Lenhammar, Sara R Henderson, Julia E A Mundy, Anthony Maxwell, Clare E M Stevenson, David M Lawson, Guido V Janssen, Geert Jan Sterk, Danijel Kikelj
Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa . Journal of medicinal chemistry 66 (2) (2023)
Andrej Emanuel Cotman, Martina Durcik, Davide Benedetto Tiz, Federica Fulgheri, Daniela Secci, Maša Sterle, Štefan Možina, Žiga Skok, Nace Zidar, Anamarija Zega, Janez Ilaš, Lucija Peterlin Mašič, Tihomir Tomašič, Diarmaid Hughes, Douglas L Huseby, Sha Cao, Linnéa Garoff, Talía Berruga Fernández, Paraskevi Giachou, Lisa Crone, Ivailo Simoff, Richard Svensson, Bryndis Birnir, Sergiy V Korol, Zhe Jin, Francisca Vicente, Maria C Ramos, Mercedes de la Cruz, Björn Glinghammar, Lena Lenhammar, Sara R Henderson, Julia E A Mundy, Anthony Maxwell, Clare E M Stevenson, David M Lawson, Guido V Janssen, Geert Jan Sterk, Danijel Kikelj
Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa . Journal of medicinal chemistry 66 (2) (2023)
Kyle M Orritt, Lipeng Feng, Juliette F Newell, Jack N Sutton, Scott Grossman, Thomas R M Germe, Lauren R Abbott, Holly L Jackson, Benjamin K L Bury, Anthony Maxwell, Martin J McPhillie, Colin W G Fishwick
De novo design of type II topoisomerase inhibitors as potential antimicrobial agents targeting a novel binding region. RSC medicinal chemistry 13 (7) (2022)
Shannon J McKie, Parth Rakesh Desai, Yeonee Seol, Adam Mb Allen, Anthony Maxwell, Keir C Neuman
Topoisomerase VI is a chirally-selective, preferential DNA decatenase. eLife 11 (2022)
Shannon J McKie, Keir C Neuman, Anthony Maxwell
DNA topoisomerases: Advances in understanding of cellular roles and multi-protein complexes via structure-function analysis. BioEssays : news and reviews in molecular, cellular and developmental biology 43 (4) (2021)
Alice L B Pyne, Agnes Noy, Kavit H S Main, Victor Velasco-Berrelleza, Michael M Piperakis, Lesley A Mitchenall, Fiorella M Cugliandolo, Joseph G Beton, Clare E M Stevenson, Bart W Hoogenboom, Andrew D Bates, Anthony Maxwell, Sarah A Harris
Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and major groove recognition by triplex-forming oligonucleotides. Nature communications 12 (1) (2021)
Anja Kolarič, Thomas R M Germe, Martina Hrast Rambaher, Clare E M Stevenson, David M Lawson, Nicolas P Burton, Judit Vörös, Anthony Maxwell, Nikola Minovski, Marko Anderluh
Potent DNA gyrase inhibitors bind asymmetrically to their target using symmetrical bifurcated halogen bonds. Nature communications 12 (1) (2021)
Kyle M Orritt, Anthony Maxwell, Colin W G Fishwick, Martin J McPhillie
Exploitation of a novel allosteric binding region in DNA gyrase and its implications for antibacterial drug discovery. Future medicinal chemistry 13 (24) (2021)
Lipeng Feng, Julia E A Mundy, Clare E M Stevenson, Lesley A Mitchenall, David M Lawson, Kaixia Mi, Anthony Maxwell
The pentapeptide-repeat protein, MfpA, interacts with mycobacterial DNA gyrase as a DNA T-segment mimic. Proceedings of the National Academy of Sciences of the United States of America 118 (11) (2021)
Natassja G Bush, Isabel Diez-Santos, Lauren R Abbott, Anthony Maxwell
Quinolones: Mechanism, Lethality and Their Contributions to Antibiotic Resistance. Molecules (Basel, Switzerland) 25 (23) (2020)
Nidda F Waraich, Shruti Jain, Sean D Colloms, William Marshall Stark, Nicolas P Burton, Anthony Maxwell
A novel decatenation assay for DNA topoisomerases using a singly-linked catenated substrate. BioTechniques 69 (5) (2020)
Katarzyna Ignasiak, Anthony Maxwell
Oxytetracycline reduces the diversity of tetracycline-resistance genes in the Galleria mellonella gut microbiome. BMC microbiology 18 (1) (2018)
Frédéric Jeannot, Thomas Taillier, Pierre Despeyroux, Stéphane Renard, Astrid Rey, Michaël Mourez, Christoph Poeverlein, Imène Khichane, Marc-Antoine Perrin, Stéphanie Versluys, Robert A Stavenger, Jianzhong Huang, Thomas Germe, Anthony Maxwell, Sha Cao, Douglas L Huseby, Diarmaid Hughes, Eric Bacqué
Imidazopyrazinones (IPYs): Non-Quinolone Bacterial Topoisomerase Inhibitors Showing Partial Cross-Resistance with Quinolones. Journal of medicinal chemistry 61 (8) (2018)
Lesley A Mitchenall, Rachel E Hipkin, Michael M Piperakis, Nicolas P Burton, Anthony Maxwell
A rapid high-resolution method for resolving DNA topoisomers. BMC research notes 11 (1) (2018)
Katarzyna Ignasiak, Anthony Maxwell
Antibiotic-resistant bacteria in the guts of insects feeding on plants: prospects for discovering plant-derived antibiotics. BMC microbiology 17 (1) (2017)
Katarzyna Ignasiak, Anthony Maxwell
Galleria mellonella (greater wax moth) larvae as a model for antibiotic susceptibility testing and acute toxicity trials. BMC research notes 10 (1) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Anthony Maxwell