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April L Risinger (April Risinger)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2022
Publications (10 Years): 28

Top Venues

Journal of natural products

Cancers

Proceedings of the National Academy of Sciences of the United States of America

Molecules (Basel, Switzerland)

Massachusetts Institute of Technology (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

Massachusetts Institute of Technology Sep 1o 2001 - May 1o 2007

United States

PHD :: Biology

Publications

Shuo Li, Mattia Mori, Mingyan Yang, Soumia Elfazazi, Rafael Hortigüela, Peter Chan, Xinyue Feng, April L Risinger, Zhiyou Yang, María Ángela Oliva, José Fernando Díaz, Wei-Shuo Fang
Targeting the tubulin C-terminal tail by charged small molecules. Organic & biomolecular chemistry (2022)
Joseph D Morris, Leila Takahashi-Ruiz, Lauren N Persi, Jonathan C Summers, Erin P McCauley, Peter Y W Chan, Gabriella Amberchan, Itzel Lizama-Chamu, David A Coppage, Phillip Crews, April L Risinger, Tyler A Johnson
Re-evaluation of the Fijianolide/Laulimalide Chemotype Suggests an Alternate Mechanism of Action for C-15/C-20 Analogs. ACS omega 7 (10) (2022)
Leila Takahashi-Ruiz, Charles S Fermaintt, Nancy J Wilkinson, Peter Y W Chan, Susan L Mooberry, April L Risinger
The Microtubule Destabilizer Eribulin Synergizes with STING Agonists to Promote Antitumor Efficacy in Triple-Negative Breast Cancer Models. Cancers 14 (23) (2022)
Leila Takahashi-Ruiz, Charles S Fermaintt, Nancy J Wilkinson, Peter Y W Chan, Susan L Mooberry, April L Risinger
The Microtubule Destabilizer Eribulin Synergizes with STING Agonists to Promote Antitumor Efficacy in Triple-Negative Breast Cancer Models. Cancers 14 (23) (2022)
Leila Takahashi-Ruiz, Joseph D Morris, Phillip Crews, Tyler A Johnson, April L Risinger
In Vivo Evaluation of (-)-Zampanolide Demonstrates Potent and Persistent Antitumor Efficacy When Targeted to the Tumor Site. Molecules (Basel, Switzerland) 27 (13) (2022)
Leila Takahashi-Ruiz, Charles S Fermaintt, Nancy J Wilkinson, Peter Y W Chan, Susan L Mooberry, April L Risinger
The Microtubule Destabilizer Eribulin Synergizes with STING Agonists to Promote Antitumor Efficacy in Triple-Negative Breast Cancer Models. Cancers 14 (23) (2022)
Han Sun, Samantha S Yee, Habtom B Gobeze, Ru He, Daniel Martinez, April L Risinger, Kirk S Schanze
One- and Two-Photon Activated Release of Oxaliplatin from a Pt(IV)-Functionalized Poly(phenylene ethynylene). ACS applied materials & interfaces 14 (14) (2022)
Leila Takahashi-Ruiz, Charles S Fermaintt, Nancy J Wilkinson, Peter Y W Chan, Susan L Mooberry, April L Risinger
The Microtubule Destabilizer Eribulin Synergizes with STING Agonists to Promote Antitumor Efficacy in Triple-Negative Breast Cancer Models. Cancers 14 (23) (2022)
Susan Matthew, Qi-Yin Chen, Ranjala Ratnayake, Charles S Fermaintt, Daniel Lucena-Agell, Francesca Bonato, Andrea E Prota, Seok Ting Lim, Xiaomeng Wang, José Fernando Díaz, April L Risinger, Valerie J Paul, María Ángela Oliva, Hendrik Luesch
Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site. Proceedings of the National Academy of Sciences of the United States of America 118 (9) (2021)
Andrew J Robles, Wentao Dai, Saikat Haldar, Hongyan Ma, Victoria M Anderson, Ross D Overacker, April L Risinger, Sandra Loesgen, Peter J Houghton, Robert H Cichewicz, Susan L Mooberry
Altertoxin II, a Highly Effective and Specific Compound against Ewing Sarcoma. Cancers 13 (24) (2021)
Charles S Fermaintt, Thilini Peramuna, Shengxin Cai, Leila Takahashi-Ruiz, Jacob Nathaniel Essif, Corena V Grant, Barry R Oâ Keefe, Susan L Mooberry, Robert H Cichewicz, April L Risinger
Yuanhuacine Is a Potent and Selective Inhibitor of the Basal-Like 2 Subtype of Triple Negative Breast Cancer with Immunogenic Potential. Cancers 13 (11) (2021)
Samantha S Yee, April L Risinger
Efficacy of a Covalent Microtubule Stabilizer in Taxane-Resistant Ovarian Cancer Models. Molecules (Basel, Switzerland) 26 (13) (2021)
April L Risinger, Shayne D Hastings, Lin Du
Taccalonolide C-6 Analogues, Including Paclitaxel Hybrids, Demonstrate Improved Microtubule Polymerizing Activities. Journal of natural products 84 (6) (2021)
Petra J Pederson, Shengxin Cai, Chase Carver, Douglas R Powell, April L Risinger, Tanja Grkovic, Barry R Oâ Keefe, Susan L Mooberry, Robert H Cichewicz
Triple-Negative Breast Cancer Cells Exhibit Differential Sensitivity to Cardenolides from Calotropis gigantea. Journal of natural products 83 (7) (2020)
Corena V Grant, Shengxin Cai, April L Risinger, Huiyun Liang, Barry R Oâ Keefe, John G Doench, Robert H Cichewicz, Susan L Mooberry
CRISPR-Cas9 Genome-Wide Knockout Screen Identifies Mechanism of Selective Activity of Dehydrofalcarinol in Mesenchymal Stem-like Triple-Negative Breast Cancer Cells. Journal of natural products 83 (10) (2020)
Yun-Seo Kil, April L Risinger, Cora L Petersen, Susan L Mooberry, Robert H Cichewicz
Leucinostatins from Ophiocordyceps spp. and Purpureocillium spp. Demonstrate Selective Antiproliferative Effects in Cells Representing the Luminal Androgen Receptor Subtype of Triple Negative Breast Cancer. Journal of natural products 83 (6) (2020)
Lin Du, Samantha S Yee, Karthik Ramachandran, April L Risinger
Elucidating target specificity of the taccalonolide covalent microtubule stabilizers employing a combinatorial chemical approach. Nature communications 11 (1) (2020)
Yun-Seo Kil, April L Risinger, Cora L Petersen, Huiyun Liang, Tanja Grkovic, Barry R Oâ Keefe, Susan L Mooberry, Robert H Cichewicz
Using the Cancer Dependency Map to Identify the Mechanism of Action of a Cytotoxic Alkenyl Derivative from the Fruit of Choerospondias axillaris. Journal of natural products 83 (3) (2020)
Francisco de Asís Balaguer, Tobias Mühlethaler, Juan Estévez-Gallego, Enrique Calvo, Juan Francisco Giménez-Abián, April L Risinger, Erik J Sorensen, Christopher D Vanderwal, Karl-Heinz Altmann, Susan L Mooberry, Michel O Steinmetz, María Ángela Oliva, Andrea E Prota, José Fernando Díaz
Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands. International journal of molecular sciences 20 (6) (2019)
Adam C Carter, Cora L Petersen, Karen L Wendt, Sara K Helff, April L Risinger, Susan L Mooberry, Robert H Cichewicz
In Situ Ring Contraction and Transformation of the Rhizoxin Macrocycle through an Abiotic Pathway. Journal of natural products 82 (4) (2019)
Shengxin Cai, April L Risinger, Cora L Petersen, Tanja Grkovic, Barry R Oâ Keefe, Susan L Mooberry, Robert H Cichewicz
Anacolosins A-F and Corymbulosins X and Y, Clerodane Diterpenes from Anacolosa clarkii Exhibiting Cytotoxicity toward Pediatric Cancer Cell Lines. Journal of natural products 82 (4) (2019)
Lin Du, April L Risinger, Samantha S Yee, Antonius R B Ola, Cynthia L Zammiello, Robert H Cichewicz, Susan L Mooberry
Identification of C-6 as a New Site for Linker Conjugation to the Taccalonolide Microtubule Stabilizers. Journal of natural products 82 (3) (2019)
Roma Kaul, April L Risinger, Susan L Mooberry
Microtubule-Targeting Drugs: More than Antimitotics. Journal of natural products 82 (3) (2019)
Corena V Grant, Chase M Carver, Shayne D Hastings, Karthik Ramachandran, Madesh Muniswamy, April L Risinger, John A Beutler, Susan L Mooberry
Triple-negative breast cancer cell line sensitivity to englerin A identifies a new, targetable subtype. Breast cancer research and treatment 177 (2) (2019)
Yun Huang, Zhiliang Li, April L Risinger, Benjamin T Enslow, Charles J Zeman, Jiang Gong, Yajing Yang, Kirk S Schanze
Fluorescence spectral shape analysis for nucleotide identification. Proceedings of the National Academy of Sciences of the United States of America 116 (31) (2019)
Antonius R B Ola, April L Risinger, Lin Du, Cynthia L Zammiello, Jiangnan Peng, Robert H Cichewicz, Susan L Mooberry
Taccalonolide Microtubule Stabilizers Generated Using Semisynthesis Define the Effects of Mono Acyloxy Moieties at C-7 or C-15 and Disubstitutions at C-7 and C-25. Journal of natural products 81 (3) (2018)
Peter Manning Lococo, April L Risinger, Hudson R Smith, Teresa S Chavera, Kelly A Berg, William P Clarke
Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy. eLife 6 (2017)
April L Risinger, Jing Li, Lin Du, Raymond Benavides, Andrew J Robles, Robert H Cichewicz, John G Kuhn, Susan L Mooberry
Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ. Journal of natural products 80 (2) (2017)

April L Risinger.css-eqlu8i{font-size:small;padding-left:4px;} (April Risinger)

Publication Activity (10 Years)

Top Topics

Top Venues

April L Risinger (April Risinger)